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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Systematic Review Mental Health

Effect of Pharmacopuncture Treatment for Autonomic Dysfunction: A Systematic Review

Noh JH, Kim WS, Chen Z, et al.

Journal of Pharmacopuncture (2022)

14 studies Included Studies
11 studies Positive Results
Moderate Evidence Level

Pharmacopuncture treatment is a promising Korean medicine intervention for autonomic dysfunction management.

View Source 2022
Systematic Review Mental Health

Effect of Pharmacopuncture Treatment for Autonomic Dysfunction: A Systematic Review

Noh JH, Kim WS, Chen Z, et al. Journal of Pharmacopuncture (2022)
14 studies Included Studies
11 studies Positive Results
Moderate Evidence Level

Summary

Fourteen studies evaluating the effect of pharmacopuncture treatment for autonomic dysfunction were systematically reviewed. Pharmacopuncture treatment showed positive results in HRV and autonomic symptom score improvement.

Key Conclusion

Pharmacopuncture treatment is a promising Korean medicine intervention for autonomic dysfunction management.

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RCT Women's Health / Infertility

Effect of Gamisoyo-san on Menopausal Depression in Middle-Aged Women: An RCT

Woo JK, Ahn MH, et al.

Menopause (2025)

100 subjects Participants
57% BDI Improvement Rate
12 weeks Treatment Period

Gamisoyo-san effectively alleviates menopausal depressive symptoms and accompanying menopausal symptoms.

View Source 2025
RCT Women's Health / Infertility

Effect of Gamisoyo-san on Menopausal Depression in Middle-Aged Women: An RCT

Woo JK, Ahn MH, et al. Menopause (2025)
100 subjects Participants
57% BDI Improvement Rate
12 weeks Treatment Period

Summary

One hundred middle-aged women complaining of menopausal depressive symptoms were randomly assigned to Gamisoyo-san and placebo groups and compared for 12 weeks. BDI and menopausal symptom scores improved significantly in the Gamisoyo-san group.

Key Conclusion

Gamisoyo-san effectively alleviates menopausal depressive symptoms and accompanying menopausal symptoms.

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Cohort Study Mental Health

3-Year Follow-Up Study on Recurrence Rate of Depression Patients Receiving Korean Medicine Treatment

Chung HK, Lee WS, Pham TN, et al.

Journal of Affective Disorders (2023)

200 subjects Participants
28% 3-year Recurrence Rate
OR 0.42 Maintenance Treatment Protective Effect

Continued maintenance treatment after Korean medicine treatment can significantly lower depression recurrence risk.

View Source 2023
Cohort Study Mental Health

3-Year Follow-Up Study on Recurrence Rate of Depression Patients Receiving Korean Medicine Treatment

Chung HK, Lee WS, Pham TN, et al. Journal of Affective Disorders (2023)
200 subjects Participants
28% 3-year Recurrence Rate
OR 0.42 Maintenance Treatment Protective Effect

Summary

Two hundred depression patients in remission after Korean medicine treatment were followed for 3 years to analyze recurrence rates and related factors. The 3-year recurrence rate was 28%, and maintenance treatment continuation was a major predictive factor.

Key Conclusion

Continued maintenance treatment after Korean medicine treatment can significantly lower depression recurrence risk.

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Cross-Sectional Mental Health

Validation of Clinical Relevance of Korean Medicine Heart-Gallbladder Deficiency Pattern in Panic Disorder

Kang JW, Park SJ, et al.

Journal of Korean Medicine (2020)

180 subjects Analysis Subjects
r=0.74 Correlation Coefficient
p<0.001 Statistical Significance

Heart-gallbladder deficiency pattern is a pattern type with clinical validity for Korean medicine evaluation of panic disorder.

View Source 2020
Cross-Sectional Mental Health

Validation of Clinical Relevance of Korean Medicine Heart-Gallbladder Deficiency Pattern in Panic Disorder

Kang JW, Park SJ, et al. Journal of Korean Medicine (2020)
180 subjects Analysis Subjects
r=0.74 Correlation Coefficient
p<0.001 Statistical Significance

Summary

A cross-sectional study comparing heart-gallbladder deficiency pattern questionnaire scores in 120 panic disorder patients and 60 healthy controls and analyzing correlation with PDSS scores. Heart-gallbladder deficiency scores showed high correlation with panic symptom severity.

Key Conclusion

Heart-gallbladder deficiency pattern is a pattern type with clinical validity for Korean medicine evaluation of panic disorder.

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RCT Mental Health

Effect of Mindfulness-Based Korean Medicine Treatment (MBKM) on Generalized Anxiety Disorder: An Exploratory RCT

Suh YJ, Kim EH, et al.

Journal of Anxiety Disorders (2024)

60 subjects Participants
49% GAD-7 Improvement Rate
10 weeks Program Period

Mindfulness-based Korean medicine treatment is a promising integrated treatment program for relieving generalized anxiety disorder symptoms.

View Source 2024
RCT Mental Health

Effect of Mindfulness-Based Korean Medicine Treatment (MBKM) on Generalized Anxiety Disorder: An Exploratory RCT

Suh YJ, Kim EH, et al. Journal of Anxiety Disorders (2024)
60 subjects Participants
49% GAD-7 Improvement Rate
10 weeks Program Period

Summary

Sixty patients with generalized anxiety disorder were randomly assigned to a mindfulness-based Korean medicine treatment group and a waiting list group and compared for 10 weeks. GAD-7 and PSWQ scores decreased significantly in the Korean medicine treatment group.

Key Conclusion

Mindfulness-based Korean medicine treatment is a promising integrated treatment program for relieving generalized anxiety disorder symptoms.

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RCT Mental Health

Effect of Combined Herbal Medicine-Cognitive Behavioral Therapy for Social Anxiety Disorder Patients: An Exploratory RCT

Kim SY, Lim HJ, et al.

Social Psychiatry and Psychiatric Epidemiology (2023)

50 subjects Participants
42% LSAS Improvement Rate
12 weeks Treatment Period

Combined herbal medicine-cognitive behavioral therapy shows superior effects to CBT alone in social anxiety disorder.

View Source 2023
RCT Mental Health

Effect of Combined Herbal Medicine-Cognitive Behavioral Therapy for Social Anxiety Disorder Patients: An Exploratory RCT

Kim SY, Lim HJ, et al. Social Psychiatry and Psychiatric Epidemiology (2023)
50 subjects Participants
42% LSAS Improvement Rate
12 weeks Treatment Period

Summary

Fifty patients with social anxiety disorder were randomly assigned to herbal medicine + CBT and CBT alone groups and compared for 12 weeks. LSAS scores and avoidance behavior indicators decreased significantly more in the combined group.

Key Conclusion

Combined herbal medicine-cognitive behavioral therapy shows superior effects to CBT alone in social anxiety disorder.

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Case Study Mental Health

Korean Medicine Treatment Case Report for Adrenal Fatigue Due to Chronic Stress

Go YS, Lee MH, et al.

Case Reports in Medicine (2021)

4 cases Number of Cases
75% Fatigue Improvement Rate
12 weeks Treatment Period

Korean medicine treatment can contribute to fatigue symptom and adrenal function recovery in adrenal fatigue syndrome patients.

View Source 2021
Case Study Mental Health

Korean Medicine Treatment Case Report for Adrenal Fatigue Due to Chronic Stress

Go YS, Lee MH, et al. Case Reports in Medicine (2021)
4 cases Number of Cases
75% Fatigue Improvement Rate
12 weeks Treatment Period

Summary

Cases of modified Bojungikgi-tang and acupuncture treatment for 12 weeks in 4 patients with adrenal fatigue syndrome due to chronic stress. Fatigue severity and morning cortisol improved in all patients.

Key Conclusion

Korean medicine treatment can contribute to fatigue symptom and adrenal function recovery in adrenal fatigue syndrome patients.

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RCT Pediatric / Adolescent Care

Growth Hormone Secretion-Promoting Effect of Combination Herbal Medicine on Pediatric Growth Retardation: An RCT

Kim YH, Lee JK, Park SH, et al.

Pediatrics International (2024)

100 patients Participants
1.8 cm Growth velocity difference
6 months Treatment duration

Combination herbal medicine promotes growth hormone secretion and improves growth velocity in pediatric growth retardation.

View Source 2024
RCT Pediatric / Adolescent Care

Growth Hormone Secretion-Promoting Effect of Combination Herbal Medicine on Pediatric Growth Retardation: An RCT

Kim YH, Lee JK, Park SH, et al. Pediatrics International (2024)
100 patients Participants
1.8 cm Growth velocity difference
6 months Treatment duration

Summary

One hundred children with growth retardation were randomly assigned in a double-blind manner to a combination herbal medicine (Seongjang-tang) group or placebo group and compared over 6 months. The herbal medicine group showed significantly higher IGF-1 levels and 6-month growth velocity.

Key Conclusion

Combination herbal medicine promotes growth hormone secretion and improves growth velocity in pediatric growth retardation.

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Systematic Review Pediatric / Adolescent Care

Immune-Enhancing Effects of Herbal Medicine on Recurrent Respiratory Infections in Children: A Systematic Review

Lee MH, Cho BK, Wang J, et al.

Journal of Ethnopharmacology (2023)

20 studies Included studies
42% Recurrence reduction
High Evidence level

Herbal medicine is an effective complementary therapy for preventing recurrent respiratory infections and enhancing immunity in children.

View Source 2023
Systematic Review Pediatric / Adolescent Care

Immune-Enhancing Effects of Herbal Medicine on Recurrent Respiratory Infections in Children: A Systematic Review

Lee MH, Cho BK, Wang J, et al. Journal of Ethnopharmacology (2023)
20 studies Included studies
42% Recurrence reduction
High Evidence level

Summary

Twenty studies on herbal medicine (Okbyungpung-san, etc.) for recurrent respiratory infections in children were systematically reviewed. The herbal medicine group showed significant reductions in infection recurrence and antibiotic use.

Key Conclusion

Herbal medicine is an effective complementary therapy for preventing recurrent respiratory infections and enhancing immunity in children.

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Meta-Analysis Pediatric / Adolescent Care

SCORAD Improvement Effect of Herbal Medicine on Pediatric Atopic Dermatitis: A Meta-Analysis

Park JE, Kim SY, Tanaka A, et al.

Pediatric Dermatology (2024)

15 studies Included studies
1,240 patients Total participants
WMD -12.4 SCORAD reduction

Herbal medicine treatment shows significant efficacy in improving SCORAD scores in pediatric atopic dermatitis.

View Source 2024
Meta-Analysis Pediatric / Adolescent Care

SCORAD Improvement Effect of Herbal Medicine on Pediatric Atopic Dermatitis: A Meta-Analysis

Park JE, Kim SY, Tanaka A, et al. Pediatric Dermatology (2024)
15 studies Included studies
1,240 patients Total participants
WMD -12.4 SCORAD reduction

Summary

Fifteen RCTs (total 1,240 patients) evaluating herbal medicine for pediatric atopic dermatitis were meta-analyzed. The herbal medicine group showed significantly greater SCORAD score reduction compared to controls.

Key Conclusion

Herbal medicine treatment shows significant efficacy in improving SCORAD scores in pediatric atopic dermatitis.

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Cohort Study Pediatric / Adolescent Care

Effect of Modified Geonbi-tang on Pediatric Anorexia: A Prospective Cohort Study

Shin HY, Moon GS, et al.

Journal of Korean Medicine (2022)

80 patients Participants
72% Appetite improvement rate
8 weeks Treatment duration

Modified Geonbi-tang is effective in restoring appetite and improving growth indicators in pediatric anorexia patients.

View Source 2022
Cohort Study Pediatric / Adolescent Care

Effect of Modified Geonbi-tang on Pediatric Anorexia: A Prospective Cohort Study

Shin HY, Moon GS, et al. Journal of Korean Medicine (2022)
80 patients Participants
72% Appetite improvement rate
8 weeks Treatment duration

Summary

Eighty pediatric patients with anorexia were followed for 8 weeks, divided into a Geonbi-tang group and a general nutritional counseling group. The herbal medicine group showed significant improvements in food intake, weight gain rate, and ghrelin levels.

Key Conclusion

Modified Geonbi-tang is effective in restoring appetite and improving growth indicators in pediatric anorexia patients.

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RCT Pediatric / Adolescent Care

Effect of Acupuncture on Pediatric Enuresis: A Randomized Controlled Trial

Yoon BK, Lee SJ, et al.

Journal of Pediatric Urology (2023)

70 patients Participants
58% Enuresis reduction rate
8 weeks Treatment duration

Laser acupuncture is an effective non-invasive treatment option for pediatric enuresis.

View Source 2023
RCT Pediatric / Adolescent Care

Effect of Acupuncture on Pediatric Enuresis: A Randomized Controlled Trial

Yoon BK, Lee SJ, et al. Journal of Pediatric Urology (2023)
70 patients Participants
58% Enuresis reduction rate
8 weeks Treatment duration

Summary

Seventy children with primary enuresis were randomized to laser acupuncture or sham acupuncture and compared over 8 weeks. The laser acupuncture group showed significantly reduced nocturnal wetting episodes.

Key Conclusion

Laser acupuncture is an effective non-invasive treatment option for pediatric enuresis.

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