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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
RCT Pediatric / Adolescent Care

Gastrointestinal Motility-Promoting Effect of Sogeonjung-tang on Pediatric Anorexia: An RCT

Jung SK, Woo HJ, et al.

World Journal of Gastroenterology (2024)

60 patients Participants
40% Gastric emptying improvement
6 weeks Treatment duration

Sogeonjung-tang promotes gastrointestinal motility and restores appetite in pediatric anorexia patients.

View Source 2024
RCT Pediatric / Adolescent Care

Gastrointestinal Motility-Promoting Effect of Sogeonjung-tang on Pediatric Anorexia: An RCT

Jung SK, Woo HJ, et al. World Journal of Gastroenterology (2024)
60 patients Participants
40% Gastric emptying improvement
6 weeks Treatment duration

Summary

Sixty children with functional anorexia were randomized to Sogeonjung-tang or placebo and compared over 6 weeks. The Sogeonjung-tang group showed significant improvements in gastric emptying time and food intake.

Key Conclusion

Sogeonjung-tang promotes gastrointestinal motility and restores appetite in pediatric anorexia patients.

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Narrative Review Pediatric / Adolescent Care

Effect of Korean Medicine Topical Preparations on Pediatric Atopic Dermatitis: A Literature Review

Cho SH, Im KJ, Liu F, et al.

Dermatologic Therapy (2022)

30 studies Reviewed papers
85% Positive outcomes
Jaungo Most frequent prescription

Korean medicine topical preparations are safe and effective adjunctive treatments for pediatric atopic dermatitis.

View Source 2022
Narrative Review Pediatric / Adolescent Care

Effect of Korean Medicine Topical Preparations on Pediatric Atopic Dermatitis: A Literature Review

Cho SH, Im KJ, Liu F, et al. Dermatologic Therapy (2022)
30 studies Reviewed papers
85% Positive outcomes
Jaungo Most frequent prescription

Summary

Thirty studies on Korean medicine topical preparations (Jaungo, Hwangryeonhaedok-tang lotion, etc.) for pediatric atopic dermatitis were comprehensively reviewed. Most topical preparations improved transepidermal water loss (TEWL) and pruritus.

Key Conclusion

Korean medicine topical preparations are safe and effective adjunctive treatments for pediatric atopic dermatitis.

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Before-After Pediatric / Adolescent Care

NK Cell Activity Enhancement Effect of Herbal Medicine for Pediatric Immunity: A Pre-Post Comparison

Han DY, Seo GR, et al.

Immunological Investigations (2023)

50 patients Participants
34% NK activity increase
12 weeks Treatment duration

Modified Bojungikgi-tang enhances innate immune function in children and contributes to infection prevention.

View Source 2023
Before-After Pediatric / Adolescent Care

NK Cell Activity Enhancement Effect of Herbal Medicine for Pediatric Immunity: A Pre-Post Comparison

Han DY, Seo GR, et al. Immunological Investigations (2023)
50 patients Participants
34% NK activity increase
12 weeks Treatment duration

Summary

Modified Bojungikgi-tang was administered for 12 weeks to 50 children with frequent colds, and NK cell activity, IgA levels, and cold frequency were measured. NK cell activity and IgA significantly increased and cold frequency decreased.

Key Conclusion

Modified Bojungikgi-tang enhances innate immune function in children and contributes to infection prevention.

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Cohort Study Pediatric / Adolescent Care

Final Adult Height in Children with Short Stature Receiving Korean Medicine Growth-Promoting Therapy: A Retrospective Cohort

Bae JH, Kim MN, et al.

Annals of Pediatric Endocrinology & Metabolism (2024)

200 patients Analysis subjects
2.8 cm Additional growth
10 years Follow-up period

Korean medicine growth therapy has a positive impact on achieving final adult height in children with short stature.

View Source 2024
Cohort Study Pediatric / Adolescent Care

Final Adult Height in Children with Short Stature Receiving Korean Medicine Growth-Promoting Therapy: A Retrospective Cohort

Bae JH, Kim MN, et al. Annals of Pediatric Endocrinology & Metabolism (2024)
200 patients Analysis subjects
2.8 cm Additional growth
10 years Follow-up period

Summary

Final adult height was retrospectively analyzed in 200 children with short stature who received Korean medicine growth-promoting therapy. An average additional growth of 2.8 cm over predicted adult height was confirmed.

Key Conclusion

Korean medicine growth therapy has a positive impact on achieving final adult height in children with short stature.

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RCT Pediatric / Adolescent Care

Effects of Herbal Medicine-Behavioral Therapy Combination Intervention for Pediatric Tic Disorders: A Multicenter RCT

Kwon HJ, Choi YH, Lee KM, et al.

European Child & Adolescent Psychiatry (2025)

120 patients Participants
65% YGTSS improvement rate
3 centers Multicenter participation

Combination of herbal medicine and behavioral therapy showed superior efficacy compared to monotherapy in pediatric tic disorder.

View Source 2025
RCT Pediatric / Adolescent Care

Effects of Herbal Medicine-Behavioral Therapy Combination Intervention for Pediatric Tic Disorders: A Multicenter RCT

Kwon HJ, Choi YH, Lee KM, et al. European Child & Adolescent Psychiatry (2025)
120 patients Participants
65% YGTSS improvement rate
3 centers Multicenter participation

Summary

One hundred twenty children with chronic tic disorder were randomly assigned to herbal medicine plus behavioral therapy, herbal medicine alone, or behavioral therapy alone groups and compared over 16 weeks. The combination group showed the greatest YGTSS score reduction.

Key Conclusion

Combination of herbal medicine and behavioral therapy showed superior efficacy compared to monotherapy in pediatric tic disorder.

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RCT Pediatric / Adolescent Care

Effect of Acupuncture on Pediatric Enuresis: A Randomized Controlled Trial

Yoon BK, Lee SJ, et al.

Journal of Pediatric Urology (2023)

70 patients Participants
58% Enuresis reduction rate
8 weeks Treatment duration

Laser acupuncture is an effective non-invasive treatment option for pediatric enuresis.

View Source 2023
RCT Pediatric / Adolescent Care

Effect of Acupuncture on Pediatric Enuresis: A Randomized Controlled Trial

Yoon BK, Lee SJ, et al. Journal of Pediatric Urology (2023)
70 patients Participants
58% Enuresis reduction rate
8 weeks Treatment duration

Summary

Seventy children with primary enuresis were randomized to laser acupuncture or sham acupuncture and compared over 8 weeks. The laser acupuncture group showed significantly reduced nocturnal wetting episodes.

Key Conclusion

Laser acupuncture is an effective non-invasive treatment option for pediatric enuresis.

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Cohort Study Pediatric / Adolescent Care

Effect of Modified Geonbi-tang on Pediatric Anorexia: A Prospective Cohort Study

Shin HY, Moon GS, et al.

Journal of Korean Medicine (2022)

80 patients Participants
72% Appetite improvement rate
8 weeks Treatment duration

Modified Geonbi-tang is effective in restoring appetite and improving growth indicators in pediatric anorexia patients.

View Source 2022
Cohort Study Pediatric / Adolescent Care

Effect of Modified Geonbi-tang on Pediatric Anorexia: A Prospective Cohort Study

Shin HY, Moon GS, et al. Journal of Korean Medicine (2022)
80 patients Participants
72% Appetite improvement rate
8 weeks Treatment duration

Summary

Eighty pediatric patients with anorexia were followed for 8 weeks, divided into a Geonbi-tang group and a general nutritional counseling group. The herbal medicine group showed significant improvements in food intake, weight gain rate, and ghrelin levels.

Key Conclusion

Modified Geonbi-tang is effective in restoring appetite and improving growth indicators in pediatric anorexia patients.

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Meta-Analysis Pediatric / Adolescent Care

SCORAD Improvement Effect of Herbal Medicine on Pediatric Atopic Dermatitis: A Meta-Analysis

Park JE, Kim SY, Tanaka A, et al.

Pediatric Dermatology (2024)

15 studies Included studies
1,240 patients Total participants
WMD -12.4 SCORAD reduction

Herbal medicine treatment shows significant efficacy in improving SCORAD scores in pediatric atopic dermatitis.

View Source 2024
Meta-Analysis Pediatric / Adolescent Care

SCORAD Improvement Effect of Herbal Medicine on Pediatric Atopic Dermatitis: A Meta-Analysis

Park JE, Kim SY, Tanaka A, et al. Pediatric Dermatology (2024)
15 studies Included studies
1,240 patients Total participants
WMD -12.4 SCORAD reduction

Summary

Fifteen RCTs (total 1,240 patients) evaluating herbal medicine for pediatric atopic dermatitis were meta-analyzed. The herbal medicine group showed significantly greater SCORAD score reduction compared to controls.

Key Conclusion

Herbal medicine treatment shows significant efficacy in improving SCORAD scores in pediatric atopic dermatitis.

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Systematic Review Pediatric / Adolescent Care

Immune-Enhancing Effects of Herbal Medicine on Recurrent Respiratory Infections in Children: A Systematic Review

Lee MH, Cho BK, Wang J, et al.

Journal of Ethnopharmacology (2023)

20 studies Included studies
42% Recurrence reduction
High Evidence level

Herbal medicine is an effective complementary therapy for preventing recurrent respiratory infections and enhancing immunity in children.

View Source 2023
Systematic Review Pediatric / Adolescent Care

Immune-Enhancing Effects of Herbal Medicine on Recurrent Respiratory Infections in Children: A Systematic Review

Lee MH, Cho BK, Wang J, et al. Journal of Ethnopharmacology (2023)
20 studies Included studies
42% Recurrence reduction
High Evidence level

Summary

Twenty studies on herbal medicine (Okbyungpung-san, etc.) for recurrent respiratory infections in children were systematically reviewed. The herbal medicine group showed significant reductions in infection recurrence and antibiotic use.

Key Conclusion

Herbal medicine is an effective complementary therapy for preventing recurrent respiratory infections and enhancing immunity in children.

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RCT Pediatric / Adolescent Care

Growth Hormone Secretion-Promoting Effect of Combination Herbal Medicine on Pediatric Growth Retardation: An RCT

Kim YH, Lee JK, Park SH, et al.

Pediatrics International (2024)

100 patients Participants
1.8 cm Growth velocity difference
6 months Treatment duration

Combination herbal medicine promotes growth hormone secretion and improves growth velocity in pediatric growth retardation.

View Source 2024
RCT Pediatric / Adolescent Care

Growth Hormone Secretion-Promoting Effect of Combination Herbal Medicine on Pediatric Growth Retardation: An RCT

Kim YH, Lee JK, Park SH, et al. Pediatrics International (2024)
100 patients Participants
1.8 cm Growth velocity difference
6 months Treatment duration

Summary

One hundred children with growth retardation were randomly assigned in a double-blind manner to a combination herbal medicine (Seongjang-tang) group or placebo group and compared over 6 months. The herbal medicine group showed significantly higher IGF-1 levels and 6-month growth velocity.

Key Conclusion

Combination herbal medicine promotes growth hormone secretion and improves growth velocity in pediatric growth retardation.

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Case Study Mental Health

Korean Medicine Treatment Case Report for Adrenal Fatigue Due to Chronic Stress

Go YS, Lee MH, et al.

Case Reports in Medicine (2021)

4 cases Number of Cases
75% Fatigue Improvement Rate
12 weeks Treatment Period

Korean medicine treatment can contribute to fatigue symptom and adrenal function recovery in adrenal fatigue syndrome patients.

View Source 2021
Case Study Mental Health

Korean Medicine Treatment Case Report for Adrenal Fatigue Due to Chronic Stress

Go YS, Lee MH, et al. Case Reports in Medicine (2021)
4 cases Number of Cases
75% Fatigue Improvement Rate
12 weeks Treatment Period

Summary

Cases of modified Bojungikgi-tang and acupuncture treatment for 12 weeks in 4 patients with adrenal fatigue syndrome due to chronic stress. Fatigue severity and morning cortisol improved in all patients.

Key Conclusion

Korean medicine treatment can contribute to fatigue symptom and adrenal function recovery in adrenal fatigue syndrome patients.

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RCT Mental Health

Effect of Combined Herbal Medicine-Cognitive Behavioral Therapy for Social Anxiety Disorder Patients: An Exploratory RCT

Kim SY, Lim HJ, et al.

Social Psychiatry and Psychiatric Epidemiology (2023)

50 subjects Participants
42% LSAS Improvement Rate
12 weeks Treatment Period

Combined herbal medicine-cognitive behavioral therapy shows superior effects to CBT alone in social anxiety disorder.

View Source 2023
RCT Mental Health

Effect of Combined Herbal Medicine-Cognitive Behavioral Therapy for Social Anxiety Disorder Patients: An Exploratory RCT

Kim SY, Lim HJ, et al. Social Psychiatry and Psychiatric Epidemiology (2023)
50 subjects Participants
42% LSAS Improvement Rate
12 weeks Treatment Period

Summary

Fifty patients with social anxiety disorder were randomly assigned to herbal medicine + CBT and CBT alone groups and compared for 12 weeks. LSAS scores and avoidance behavior indicators decreased significantly more in the combined group.

Key Conclusion

Combined herbal medicine-cognitive behavioral therapy shows superior effects to CBT alone in social anxiety disorder.

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