금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
🔍

Total 1642 papers

RCT Respiratory Conditions

Effect of Cheongpyesagan-tang in Chronic Cough Patients: A Randomized Controlled Trial

Choi YS, Kim HM, et al.

Respiratory Medicine (2023)

70 patients Participants
55% Cough frequency reduction
8 weeks Treatment duration

Cheongpyesagan-tang is effective in reducing cough frequency and severity in patients with unexplained chronic cough.

RCT Respiratory Conditions

Effect of Cheongpyesagan-tang in Chronic Cough Patients: A Randomized Controlled Trial

Choi YS, Kim HM, et al. Respiratory Medicine (2023)
70 patients Participants
55% Cough frequency reduction
8 weeks Treatment duration

Summary

Seventy patients with unexplained chronic cough were randomly assigned to a Cheongpyesagan-tang or placebo group and compared over 8 weeks. The herbal medicine group showed significant reductions in 24-hour cough frequency and cough VAS.

Key Conclusion

Cheongpyesagan-tang is effective in reducing cough frequency and severity in patients with unexplained chronic cough.

RCT Respiratory Conditions

Synergistic Effect of Korean Medicine Breathing Exercises and Herbal Medicine for Pulmonary Function Improvement: An RCT

Ahn MH, Jung SK, et al.

Journal of Cardiopulmonary Rehabilitation and Prevention (2023)

100 patients Participants
3-arm comparison Study design
12 weeks Treatment duration

Combination of Korean medicine breathing exercises and herbal medicine shows synergistic effects on pulmonary function improvement.

RCT Respiratory Conditions

Synergistic Effect of Korean Medicine Breathing Exercises and Herbal Medicine for Pulmonary Function Improvement: An RCT

Ahn MH, Jung SK, et al. Journal of Cardiopulmonary Rehabilitation and Prevention (2023)
100 patients Participants
3-arm comparison Study design
12 weeks Treatment duration

Summary

One hundred patients with reduced pulmonary function were randomly assigned to Korean medicine breathing exercise plus herbal medicine, breathing exercise alone, or control groups and compared over 12 weeks. The combination group showed the greatest improvements in FVC, FEV1, and MIP.

Key Conclusion

Combination of Korean medicine breathing exercises and herbal medicine shows synergistic effects on pulmonary function improvement.

Narrative Review Respiratory Conditions

Korean Medicine Treatment for Post-Infectious Chronic Cough: A Literature Review

Son KJ, Park DH, et al.

Pulmonary Pharmacology & Therapeutics (2022)

25 studies Reviewed papers
3 types Major mechanisms
High Clinical applicability

Korean medicine treatment is effective in modulating cough reflex hypersensitivity and airway inflammation in post-infectious chronic cough.

Narrative Review Respiratory Conditions

Korean Medicine Treatment for Post-Infectious Chronic Cough: A Literature Review

Son KJ, Park DH, et al. Pulmonary Pharmacology & Therapeutics (2022)
25 studies Reviewed papers
3 types Major mechanisms
High Clinical applicability

Summary

Twenty-five studies on the effects and mechanisms of Korean medicine treatment for post-infectious chronic cough were comprehensively reviewed.

Key Conclusion

Korean medicine treatment is effective in modulating cough reflex hypersensitivity and airway inflammation in post-infectious chronic cough.

Case Study Respiratory Conditions

Korean Medicine Treatment Experience for Asthma-COPD Overlap Syndrome: A Case Report

Kang TY, Shin BK, et al.

Journal of Korean Medicine (2020)

5 patients Cases
60% Inhaler reduction success
6 months Follow-up period

Korean medicine treatment can contribute adjunctively to symptom management and inhaler reduction in ACO patients.

Case Study Respiratory Conditions

Korean Medicine Treatment Experience for Asthma-COPD Overlap Syndrome: A Case Report

Kang TY, Shin BK, et al. Journal of Korean Medicine (2020)
5 patients Cases
60% Inhaler reduction success
6 months Follow-up period

Summary

Pattern-differentiated herbal medicine and acupuncture were performed in 5 patients with asthma-COPD overlap syndrome (ACO). Three patients successfully reduced inhaler use and stabilized pulmonary function.

Key Conclusion

Korean medicine treatment can contribute adjunctively to symptom management and inhaler reduction in ACO patients.

RCT Respiratory Conditions

Effect of Korean Medicine Preventive Treatment on Particulate Matter Exposure and Respiratory Symptoms

Go SH, Lee MJ, et al.

Environmental Health Perspectives (2024)

200 patients Participants
41% Symptom occurrence reduction
3 months Observation period

Korean medicine preventive treatment is effective in reducing the occurrence of particulate matter-related respiratory symptoms.

RCT Respiratory Conditions

Effect of Korean Medicine Preventive Treatment on Particulate Matter Exposure and Respiratory Symptoms

Go SH, Lee MJ, et al. Environmental Health Perspectives (2024)
200 patients Participants
41% Symptom occurrence reduction
3 months Observation period

Summary

Two hundred residents of high particulate matter exposure areas were divided into a Korean medicine preventive treatment group and a control group, and respiratory symptom occurrence was compared during 3 months of high concentration periods. The Korean medicine treatment group had significantly lower respiratory symptom occurrence rates.

Key Conclusion

Korean medicine preventive treatment is effective in reducing the occurrence of particulate matter-related respiratory symptoms.

Meta-Analysis Respiratory Conditions

Meta-Analysis of Pharmacopuncture for Respiratory Diseases

Woo BH, Kim SR, Patel A, et al.

Journal of Pharmacopuncture (2025)

8 studies Included studies
620 patients Total participants
p<0.05 Pulmonary function improvement

Pharmacopuncture is an effective adjunctive intervention for respiratory disease management.

Meta-Analysis Respiratory Conditions

Meta-Analysis of Pharmacopuncture for Respiratory Diseases

Woo BH, Kim SR, Patel A, et al. Journal of Pharmacopuncture (2025)
8 studies Included studies
620 patients Total participants
p<0.05 Pulmonary function improvement

Summary

Eight RCTs (total 620 patients) evaluating pharmacopuncture for respiratory diseases (asthma, COPD, chronic cough) were meta-analyzed. The pharmacopuncture group showed significant improvements in symptom scores and pulmonary function.

Key Conclusion

Pharmacopuncture is an effective adjunctive intervention for respiratory disease management.

Case Study Respiratory Conditions

Effect of Korean Medicine Treatment in Patients with Bronchiectasis: A Case Series

Jeon HJ, Cho MK, et al.

Respiratory Medicine Case Reports (2021)

7 patients Cases
57% Sputum reduction
12 weeks Treatment duration

Korean medicine treatment can be utilized adjunctively for symptom management in bronchiectasis patients.

Case Study Respiratory Conditions

Effect of Korean Medicine Treatment in Patients with Bronchiectasis: A Case Series

Jeon HJ, Cho MK, et al. Respiratory Medicine Case Reports (2021)
7 patients Cases
57% Sputum reduction
12 weeks Treatment duration

Summary

Herbal medicine and acupuncture were performed for 12 weeks on 7 patients with bronchiectasis. Decreased sputum volume, reduced acute exacerbation frequency, and improved SGRQ scores were observed.

Key Conclusion

Korean medicine treatment can be utilized adjunctively for symptom management in bronchiectasis patients.

Systematic Review Respiratory Conditions

Antioxidant and Anti-Inflammatory Effects of Herbal Medicine in COPD: A Systematic Review

Moon SY, Kim GH, Wang Z, et al.

Oxidative Medicine and Cellular Longevity (2023)

28 studies Included studies
20 studies Positive results
Moderate-High Evidence level

Herbal medicine is effective in regulating oxidative stress and systemic inflammation in COPD.

Systematic Review Respiratory Conditions

Antioxidant and Anti-Inflammatory Effects of Herbal Medicine in COPD: A Systematic Review

Moon SY, Kim GH, Wang Z, et al. Oxidative Medicine and Cellular Longevity (2023)
28 studies Included studies
20 studies Positive results
Moderate-High Evidence level

Summary

Twenty-eight basic and clinical studies on antioxidant and anti-inflammatory effects of herbal medicine for COPD were systematically reviewed. Positive results were reported on various indicators including SOD increase, MDA reduction, and CRP reduction.

Key Conclusion

Herbal medicine is effective in regulating oxidative stress and systemic inflammation in COPD.

Before-After Respiratory Conditions

Changes in Cough Reflex Sensitivity After Herbal Medicine Treatment in Chronic Cough Patients: An Exploratory Study

Lee TH, Kang YM, et al.

Cough (2024)

35 patients Participants
2-fold Cough threshold elevation
8 weeks Treatment duration

Herbal medicine produces effects through normalization of hypersensitive cough reflex in chronic cough patients.

Before-After Respiratory Conditions

Changes in Cough Reflex Sensitivity After Herbal Medicine Treatment in Chronic Cough Patients: An Exploratory Study

Lee TH, Kang YM, et al. Cough (2024)
35 patients Participants
2-fold Cough threshold elevation
8 weeks Treatment duration

Summary

Herbal medicine was administered for 8 weeks to 35 patients with chronic cough, and changes in cough reflex sensitivity were measured by capsaicin cough provocation test. Cough threshold (C5) significantly increased after herbal medicine administration.

Key Conclusion

Herbal medicine produces effects through normalization of hypersensitive cough reflex in chronic cough patients.

Cohort Study Respiratory Conditions

Cost-Effectiveness Analysis of Korean Medicine Treatment in Asthma Management: Health Insurance Claims Data

Ryu MH, Cho KJ, Park EJ, et al.

Value in Health (2023)

4,800 patients Analysis population
22% Medical cost savings
35% ED visit reduction

Korean medicine combination treatment contributes to total medical cost reduction and decreased emergency department visits in asthma patients.

Cohort Study Respiratory Conditions

Cost-Effectiveness Analysis of Korean Medicine Treatment in Asthma Management: Health Insurance Claims Data

Ryu MH, Cho KJ, Park EJ, et al. Value in Health (2023)
4,800 patients Analysis population
22% Medical cost savings
35% ED visit reduction

Summary

Health insurance claims data were utilized to comparatively analyze medical costs and emergency department visits between Korean medicine combination treatment (1,200 patients) and Western medicine alone (3,600 patients) groups among asthma patients.

Key Conclusion

Korean medicine combination treatment contributes to total medical cost reduction and decreased emergency department visits in asthma patients.

Cohort Study Respiratory Conditions

Preventive Effects of Herbal Medicine in Children with Recurrent Bronchitis: A Cohort Study

Noh JW, Ahn SY, et al.

Pediatric Pulmonology (2024)

120 patients Participants
48% Recurrence reduction
12 months Follow-up period

Herbal medicine preventive treatment is effective for preventing recurrence in children with recurrent bronchitis.

Cohort Study Respiratory Conditions

Preventive Effects of Herbal Medicine in Children with Recurrent Bronchitis: A Cohort Study

Noh JW, Ahn SY, et al. Pediatric Pulmonology (2024)
120 patients Participants
48% Recurrence reduction
12 months Follow-up period

Summary

One hundred twenty children with recurrent bronchitis (4 or more per year) were followed for 12 months, divided into an herbal medicine preventive treatment group and a non-treatment group. The herbal medicine group showed significant reductions in bronchitis recurrence frequency and antibiotic use.

Key Conclusion

Herbal medicine preventive treatment is effective for preventing recurrence in children with recurrent bronchitis.

RCT Respiratory Conditions

Respiratory Muscle Strength Improvement Effect of Herbal Medicine in Elderly with Reduced Pulmonary Function: An RCT

Song GH, Min JK, et al.

Age and Ageing (2022)

80 patients Participants
18% MIP improvement
12 weeks Treatment duration

Herbal medicine is effective for improving respiratory muscle strength and pulmonary function decline in the elderly.

RCT Respiratory Conditions

Respiratory Muscle Strength Improvement Effect of Herbal Medicine in Elderly with Reduced Pulmonary Function: An RCT

Song GH, Min JK, et al. Age and Ageing (2022)
80 patients Participants
18% MIP improvement
12 weeks Treatment duration

Summary

Eighty elderly patients aged 65 or older with reduced pulmonary function were randomly assigned to an herbal medicine or placebo group and compared over 12 weeks. The herbal medicine group showed significant improvements in MIP (maximum inspiratory pressure) and FVC.

Key Conclusion

Herbal medicine is effective for improving respiratory muscle strength and pulmonary function decline in the elderly.