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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Systematic Review Neurological Disorders

Systematic Review of Korean Medicine Treatment for Diabetic Peripheral Neuropathy

Shin DK, Kim AR, Chen L, et al.

Journal of Diabetes Research (2023)

25 studies Included Studies
18 studies Positive Results
Moderate Evidence Level

Korean medicine treatment can be utilized as an adjunctive treatment for symptom relief and nerve function improvement in diabetic peripheral neuropathy.

View Source 2023
Systematic Review Neurological Disorders

Systematic Review of Korean Medicine Treatment for Diabetic Peripheral Neuropathy

Shin DK, Kim AR, Chen L, et al. Journal of Diabetes Research (2023)
25 studies Included Studies
18 studies Positive Results
Moderate Evidence Level

Summary

Twenty-five studies on Korean medicine treatment (acupuncture, herbal medicine, pharmacopuncture) for diabetic peripheral neuropathy were systematically reviewed. Nerve conduction velocity (NCV) and symptom scores improved in most studies.

Key Conclusion

Korean medicine treatment can be utilized as an adjunctive treatment for symptom relief and nerve function improvement in diabetic peripheral neuropathy.

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Case Study Neurological Disorders

Effect of Thread Embedding Therapy for Facial Palsy Sequelae: A Case Series

Han GJ, Park WR, et al.

Journal of Acupuncture and Meridian Studies (2021)

12 cases Number of Cases
75% Improvement Rate
3 months Follow-up Period

Thread embedding therapy can contribute to facial function and symmetry improvement in patients with chronic facial palsy sequelae.

View Source 2021
Case Study Neurological Disorders

Effect of Thread Embedding Therapy for Facial Palsy Sequelae: A Case Series

Han GJ, Park WR, et al. Journal of Acupuncture and Meridian Studies (2021)
12 cases Number of Cases
75% Improvement Rate
3 months Follow-up Period

Summary

A case report of thread embedding therapy in 12 patients with persistent sequelae after facial palsy for more than 6 months. After the procedure, Sunnybrook scores and facial symmetry indices improved.

Key Conclusion

Thread embedding therapy can contribute to facial function and symmetry improvement in patients with chronic facial palsy sequelae.

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RCT Neurological Disorders

Effect of Moxibustion Treatment for Cold Hypersensitivity: A Randomized Controlled Trial

Kang HW, Lee JA, et al.

Evidence-Based Complementary and Alternative Medicine (2022)

100 subjects Participants
3.4 points VAS Reduction
6 weeks Treatment Period

Moxibustion treatment improves both subjective cold sensation and objective blood flow indicators in cold hypersensitivity patients.

View Source 2022
RCT Neurological Disorders

Effect of Moxibustion Treatment for Cold Hypersensitivity: A Randomized Controlled Trial

Kang HW, Lee JA, et al. Evidence-Based Complementary and Alternative Medicine (2022)
100 subjects Participants
3.4 points VAS Reduction
6 weeks Treatment Period

Summary

One hundred patients with cold hypersensitivity of hands and feet were randomly assigned to moxibustion treatment and sham moxibustion groups and compared for 6 weeks. The moxibustion treatment group showed significant improvements in cold sensation VAS and peripheral vascular resistance index.

Key Conclusion

Moxibustion treatment improves both subjective cold sensation and objective blood flow indicators in cold hypersensitivity patients.

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Cohort Study Neurological Disorders

Long-Term Effect of Combined Herbal Medicine-Acupuncture Treatment for Sensorineural Tinnitus: A 2-Year Cohort

Oh SH, Jeon MK, Lee BY, et al.

International Tinnitus Journal (2024)

180 subjects Participants
2 years Follow-up Period
43% THI Improvement Rate

Combined herbal medicine-acupuncture treatment is an effective treatment strategy for long-term management of sensorineural tinnitus.

View Source 2024
Cohort Study Neurological Disorders

Long-Term Effect of Combined Herbal Medicine-Acupuncture Treatment for Sensorineural Tinnitus: A 2-Year Cohort

Oh SH, Jeon MK, Lee BY, et al. International Tinnitus Journal (2024)
180 subjects Participants
2 years Follow-up Period
43% THI Improvement Rate

Summary

One hundred eighty patients with sensorineural tinnitus were divided into combined herbal medicine-acupuncture treatment and standard treatment groups and followed for 2 years. THI score improvement was greater and more sustained in the combined treatment group.

Key Conclusion

Combined herbal medicine-acupuncture treatment is an effective treatment strategy for long-term management of sensorineural tinnitus.

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Meta-Analysis Neurological Disorders

Preventive Effect of Acupuncture Treatment in Migraine Patients: A Meta-Analysis

Lim SH, Chang GT, Yamada K, et al.

Headache (2023)

16 studies Included Studies
2,340 subjects Total Participants
-2.8 days Monthly Migraine Reduction

Acupuncture treatment is effective for preventive treatment of migraine and can be considered as an alternative to pharmacological prophylaxis.

View Source 2023
Meta-Analysis Neurological Disorders

Preventive Effect of Acupuncture Treatment in Migraine Patients: A Meta-Analysis

Lim SH, Chang GT, Yamada K, et al. Headache (2023)
16 studies Included Studies
2,340 subjects Total Participants
-2.8 days Monthly Migraine Reduction

Summary

A meta-analysis of 16 RCTs (total 2,340 subjects) evaluating the effect of acupuncture treatment for migraine prevention. Acupuncture treatment significantly reduced monthly migraine days.

Key Conclusion

Acupuncture treatment is effective for preventive treatment of migraine and can be considered as an alternative to pharmacological prophylaxis.

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Before-After Neurological Disorders

Effect of Korean Medicine Combined Treatment for Benign Paroxysmal Positional Vertigo: A Pre-Post Comparison Study

Seo YM, Cho KH, et al.

Journal of Korean Medicine Rehabilitation (2020)

55 subjects Participants
18% Recurrence Rate Reduction
6 months Follow-up Period

Combined Korean medicine treatment provides additional benefits in symptom improvement and recurrence prevention in BPPV patients.

View Source 2020
Before-After Neurological Disorders

Effect of Korean Medicine Combined Treatment for Benign Paroxysmal Positional Vertigo: A Pre-Post Comparison Study

Seo YM, Cho KH, et al. Journal of Korean Medicine Rehabilitation (2020)
55 subjects Participants
18% Recurrence Rate Reduction
6 months Follow-up Period

Summary

A pre-post comparison study combining canalith repositioning maneuvers with herbal medicine and acupuncture treatment in 55 patients with benign paroxysmal positional vertigo (BPPV). DHI scores and recurrence rates were significantly superior to the canalith repositioning maneuver alone group.

Key Conclusion

Combined Korean medicine treatment provides additional benefits in symptom improvement and recurrence prevention in BPPV patients.

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RCT Neurological Disorders

Effect of Acupuncture Treatment for Chemotherapy-Induced Peripheral Neuropathy: An RCT

Jung WM, Lee HY, Park JH, et al.

JAMA Network Open (2025)

160 subjects Participants
72% Symptom Improvement Rate
12 weeks Treatment Period

Acupuncture treatment is effective for symptom and nerve function improvement in chemotherapy-induced peripheral neuropathy.

View Source 2025
RCT Neurological Disorders

Effect of Acupuncture Treatment for Chemotherapy-Induced Peripheral Neuropathy: An RCT

Jung WM, Lee HY, Park JH, et al. JAMA Network Open (2025)
160 subjects Participants
72% Symptom Improvement Rate
12 weeks Treatment Period

Summary

One hundred sixty cancer patients with chemotherapy-induced peripheral neuropathy were randomly assigned to acupuncture treatment and sham acupuncture groups and compared for 12 weeks. The acupuncture treatment group showed significant improvements in FACT/GOG-Ntx scores and NCV.

Key Conclusion

Acupuncture treatment is effective for symptom and nerve function improvement in chemotherapy-induced peripheral neuropathy.

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Cross-Sectional Neurological Disorders

Correlation Between Cold Hypersensitivity and Autonomic Function: A Korean Medicine Clinical Cross-Sectional Study

Bae GM, Kim NR, et al.

Autonomic Neuroscience (2022)

300 subjects Analysis Subjects
p<0.001 HRV Difference
LF/HF Elevation Sympathetic Hyperactivity

Cold hypersensitivity is closely related to autonomic dysfunction, and Korean medicine autonomic regulation treatment is needed.

View Source 2022
Cross-Sectional Neurological Disorders

Correlation Between Cold Hypersensitivity and Autonomic Function: A Korean Medicine Clinical Cross-Sectional Study

Bae GM, Kim NR, et al. Autonomic Neuroscience (2022)
300 subjects Analysis Subjects
p<0.001 HRV Difference
LF/HF Elevation Sympathetic Hyperactivity

Summary

A cross-sectional study comparing heart rate variability (HRV) and peripheral body temperature in 200 cold hypersensitivity patients and 100 healthy controls. Sympathetic-parasympathetic imbalance was significantly observed in cold hypersensitivity patients.

Key Conclusion

Cold hypersensitivity is closely related to autonomic dysfunction, and Korean medicine autonomic regulation treatment is needed.

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RCT Neurological Disorders

Comparison of Acupuncture Treatment and Carbamazepine for Trigeminal Neuralgia: A Non-Inferiority RCT

Yang JM, Lee KW, Patel S, et al.

Pain (2024)

120 subjects Participants
Non-inferiority confirmed Main Outcome
8 weeks Treatment Period

Acupuncture treatment shows non-inferior effects to carbamazepine in trigeminal neuralgia management with a superior side effect profile.

View Source 2024
RCT Neurological Disorders

Comparison of Acupuncture Treatment and Carbamazepine for Trigeminal Neuralgia: A Non-Inferiority RCT

Yang JM, Lee KW, Patel S, et al. Pain (2024)
120 subjects Participants
Non-inferiority confirmed Main Outcome
8 weeks Treatment Period

Summary

One hundred twenty patients with trigeminal neuralgia were randomly assigned to acupuncture treatment and carbamazepine groups, and non-inferiority was evaluated for 8 weeks. Pain relief in the acupuncture treatment group was non-inferior to carbamazepine, and side effects were significantly fewer.

Key Conclusion

Acupuncture treatment shows non-inferior effects to carbamazepine in trigeminal neuralgia management with a superior side effect profile.

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Cohort Study Neurological Disorders

Predictive Factors of Korean Medicine Treatment Outcome in Bell's Palsy Patients: A Multivariate Analysis

Cho YJ, Im JY, et al.

Journal of Neurological Sciences (2021)

380 subjects Analysis Subjects
OR 3.2 Early Treatment Effect
7 days Optimal Treatment Start Day

Early treatment initiation is the most important recovery predictive factor in Korean medicine treatment of Bell's palsy.

View Source 2021
Cohort Study Neurological Disorders

Predictive Factors of Korean Medicine Treatment Outcome in Bell's Palsy Patients: A Multivariate Analysis

Cho YJ, Im JY, et al. Journal of Neurological Sciences (2021)
380 subjects Analysis Subjects
OR 3.2 Early Treatment Effect
7 days Optimal Treatment Start Day

Summary

Medical records of 380 Bell's palsy patients receiving Korean medicine treatment were retrospectively analyzed, and recovery predictive factors were multivariate-analyzed. Treatment initiation within 7 days of onset, young age, and mild severity were independent predictive factors for rapid recovery.

Key Conclusion

Early treatment initiation is the most important recovery predictive factor in Korean medicine treatment of Bell's palsy.

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Before-After Neurological Disorders

Korean Medicine Combined Treatment for Tinnitus After Sudden Hearing Loss: A Pre-Post Comparison Study

Moon SK, Hwang WJ, et al.

Auris Nasus Larynx (2023)

40 subjects Participants
38% THI Improvement
8 weeks Treatment Period

Korean medicine combined treatment is an effective treatment option for managing residual tinnitus after sudden hearing loss.

View Source 2023
Before-After Neurological Disorders

Korean Medicine Combined Treatment for Tinnitus After Sudden Hearing Loss: A Pre-Post Comparison Study

Moon SK, Hwang WJ, et al. Auris Nasus Larynx (2023)
40 subjects Participants
38% THI Improvement
8 weeks Treatment Period

Summary

Herbal medicine (modified Imyeong-san) and auricular acupuncture were administered for 8 weeks to 40 patients with residual tinnitus after sudden hearing loss. THI scores and tinnitus matching loudness decreased significantly.

Key Conclusion

Korean medicine combined treatment is an effective treatment option for managing residual tinnitus after sudden hearing loss.

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Cross-Sectional Neurological Disorders

Concordance Analysis Between Korean Medicine Headache Classification and Western Medicine Classification

Ryu HK, Son CG, Liu M, et al.

Headache (2022)

500 subjects Analysis Subjects
κ=0.58 Concordance
8 types Pattern Types

Korean medicine pattern classification provides complementary information for distinguishing headache subtypes and can be utilized in integrated practice.

View Source 2022
Cross-Sectional Neurological Disorders

Concordance Analysis Between Korean Medicine Headache Classification and Western Medicine Classification

Ryu HK, Son CG, Liu M, et al. Headache (2022)
500 subjects Analysis Subjects
κ=0.58 Concordance
8 types Pattern Types

Summary

A cross-sectional study analyzing concordance by simultaneously performing Korean medicine pattern classification and ICHD-3 classification in 500 headache patients. Significant associations between specific pattern types and headache subtypes were confirmed.

Key Conclusion

Korean medicine pattern classification provides complementary information for distinguishing headache subtypes and can be utilized in integrated practice.

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