금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
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Total 1642 papers

Case Study Men's Health / Urology

Case Series of Male Infertility Patients Successfully Achieving Natural Pregnancy After Herbal Medicine Treatment

Yun JM, Choi DS, et al.

Integrative Medicine Research (2021)

8 cases Number of Cases
5.2 months Average Treatment Period
100% Pregnancy Success Rate

Herbal medicine treatment can enable natural pregnancy by improving semen parameters even in severe male infertility patients.

Case Study Men's Health / Urology

Case Series of Male Infertility Patients Successfully Achieving Natural Pregnancy After Herbal Medicine Treatment

Yun JM, Choi DS, et al. Integrative Medicine Research (2021)
8 cases Number of Cases
5.2 months Average Treatment Period
100% Pregnancy Success Rate

Summary

Case series reports of natural pregnancy success after herbal medicine treatment in 8 male infertility patients diagnosed with severe oligospermia or asthenospermia. Average treatment duration was 5.2 months.

Key Conclusion

Herbal medicine treatment can enable natural pregnancy by improving semen parameters even in severe male infertility patients.

Cross-Sectional Men's Health / Urology

Correlation Between Male Lower Urinary Tract Symptoms and Korean Medicine Pattern Types: Multivariate Analysis

Kim DY, Chung SH, Lee PW, et al.

European Urology Focus (2023)

320 subjects Analysis Subjects
5 types Pattern Types
p<0.01 Kidney Yang Deficiency Correlation

Korean medicine pattern types show significant correlation with severity of male lower urinary tract symptoms and can be utilized in personalized treatment.

Cross-Sectional Men's Health / Urology

Correlation Between Male Lower Urinary Tract Symptoms and Korean Medicine Pattern Types: Multivariate Analysis

Kim DY, Chung SH, Lee PW, et al. European Urology Focus (2023)
320 subjects Analysis Subjects
5 types Pattern Types
p<0.01 Kidney Yang Deficiency Correlation

Summary

The correlation between pattern types, symptom severity, and prostate size was multivariate-analyzed in 320 male lower urinary tract symptom patients. IPSS and prostate size were highest in the kidney yang deficiency type.

Key Conclusion

Korean medicine pattern types show significant correlation with severity of male lower urinary tract symptoms and can be utilized in personalized treatment.

RCT Men's Health / Urology

Comparison of Effects of Electroacupuncture and Body Acupuncture for Erectile Dysfunction: A Randomized Controlled Trial

Song HJ, Kang MK, et al.

Acupuncture in Medicine (2022)

80 subjects Participants
6.3 vs 3.9 points IIEF-5 Improvement Comparison
10 weeks Treatment Period

Electroacupuncture shows superior effects to body acupuncture in erectile dysfunction treatment and can be prioritized for consideration.

RCT Men's Health / Urology

Comparison of Effects of Electroacupuncture and Body Acupuncture for Erectile Dysfunction: A Randomized Controlled Trial

Song HJ, Kang MK, et al. Acupuncture in Medicine (2022)
80 subjects Participants
6.3 vs 3.9 points IIEF-5 Improvement Comparison
10 weeks Treatment Period

Summary

Eighty patients with erectile dysfunction were randomly assigned to electroacupuncture and body acupuncture groups, and treatment effects were compared for 10 weeks. The electroacupuncture group showed significantly greater IIEF-5 score improvement and faster effect onset.

Key Conclusion

Electroacupuncture shows superior effects to body acupuncture in erectile dysfunction treatment and can be prioritized for consideration.

Cohort Study Men's Health / Urology

Cost-Effectiveness Analysis of Korean Medicine Combined Treatment for Male Climacteric Symptoms

Lee BK, Han JH, Singh R, et al.

Value in Health Regional Issues (2024)

160 subjects Analysis Subjects
$2,340 Cost Savings per QALY
ICER superior Cost-Effectiveness Result

Korean medicine combined treatment can be a cost-effective alternative for male climacteric management.

Cohort Study Men's Health / Urology

Cost-Effectiveness Analysis of Korean Medicine Combined Treatment for Male Climacteric Symptoms

Lee BK, Han JH, Singh R, et al. Value in Health Regional Issues (2024)
160 subjects Analysis Subjects
$2,340 Cost Savings per QALY
ICER superior Cost-Effectiveness Result

Summary

The cost-effectiveness of Korean medicine combined treatment was comparatively analyzed with testosterone replacement therapy in 160 male climacteric syndrome patients. Korean medicine treatment showed superiority in cost per QALY.

Key Conclusion

Korean medicine combined treatment can be a cost-effective alternative for male climacteric management.

Before-After Men's Health / Urology

Effect of Korean Medicine Sitz Bath Treatment on Pelvic Pain in Chronic Prostatitis Patients

Woo SJ, Park GN, et al.

Urological Research (2019)

35 subjects Participants
48% Pain Reduction Rate
4 weeks Treatment Period

Korean medicine sitz baths are a safe and effective adjunctive treatment for pelvic pain relief in chronic prostatitis patients.

Before-After Men's Health / Urology

Effect of Korean Medicine Sitz Bath Treatment on Pelvic Pain in Chronic Prostatitis Patients

Woo SJ, Park GN, et al. Urological Research (2019)
35 subjects Participants
48% Pain Reduction Rate
4 weeks Treatment Period

Summary

Herbal medicine-based sitz baths were administered daily for 4 weeks to 35 patients with chronic prostatitis/chronic pelvic pain syndrome. Pelvic pain VAS scores and NIH-CPSI pain subscales decreased significantly.

Key Conclusion

Korean medicine sitz baths are a safe and effective adjunctive treatment for pelvic pain relief in chronic prostatitis patients.

Narrative Review Men's Health / Urology

Integrated Review on the Male Hormone Regulation Mechanism of Kidney-Tonifying Herbal Medicine

Cho MH, Lee YR, Zhang L, et al.

Frontiers in Pharmacology (2025)

52 sources Reviewed Literature
4 mechanisms Main Mechanisms
High Evidence Level

Kidney-tonifying herbal medicine regulates male hormone balance through multiple mechanisms, contributing to male health enhancement.

Narrative Review Men's Health / Urology

Integrated Review on the Male Hormone Regulation Mechanism of Kidney-Tonifying Herbal Medicine

Cho MH, Lee YR, Zhang L, et al. Frontiers in Pharmacology (2025)
52 sources Reviewed Literature
4 mechanisms Main Mechanisms
High Evidence Level

Summary

Basic and clinical studies on the male hormone regulation mechanism of kidney-tonifying herbal medicine (deer antler, Epimedium, Cuscuta) were integratively reviewed. Various mechanisms including hypothalamus-pituitary-gonadal axis regulation and antioxidant action were confirmed.

Key Conclusion

Kidney-tonifying herbal medicine regulates male hormone balance through multiple mechanisms, contributing to male health enhancement.

Before-After Men's Health / Urology

Doppler Ultrasound Evaluation of Acupuncture Treatment Effect on Corpus Cavernosum Blood Flow: An Exploratory Study

Han WS, Kim JB, et al.

Journal of Sexual Medicine (2020)

25 subjects Participants
22% PSV Increase Rate
p<0.05 Statistical Significance

Acupuncture treatment can contribute to vasogenic erectile dysfunction treatment by improving corpus cavernosum blood flow.

Before-After Men's Health / Urology

Doppler Ultrasound Evaluation of Acupuncture Treatment Effect on Corpus Cavernosum Blood Flow: An Exploratory Study

Han WS, Kim JB, et al. Journal of Sexual Medicine (2020)
25 subjects Participants
22% PSV Increase Rate
p<0.05 Statistical Significance

Summary

Pre- and post-acupuncture penile Doppler ultrasound was performed in 25 vasogenic erectile dysfunction patients to objectively evaluate cavernosum blood flow changes. PSV and EDV indicators improved significantly.

Key Conclusion

Acupuncture treatment can contribute to vasogenic erectile dysfunction treatment by improving corpus cavernosum blood flow.

RCT Neurological Disorders

Effect of Combined Acupuncture and Herbal Medicine Treatment for Acute Facial Palsy: A Multicenter Randomized Controlled Trial

Park SY, Kim HJ, Choi MS, et al.

Neurology (2024)

240 subjects Participants
89% Complete Recovery Rate
5 institutions Multicenter Participation

Combined acupuncture-herbal medicine treatment significantly improved recovery rate and recovery speed in acute facial palsy patients.

RCT Neurological Disorders

Effect of Combined Acupuncture and Herbal Medicine Treatment for Acute Facial Palsy: A Multicenter Randomized Controlled Trial

Park SY, Kim HJ, Choi MS, et al. Neurology (2024)
240 subjects Participants
89% Complete Recovery Rate
5 institutions Multicenter Participation

Summary

Two hundred forty patients with acute Bell's palsy were recruited from 5 Korean medicine hospitals, and combined acupuncture-herbal medicine treatment was compared with steroid alone. After 12 weeks, House-Brackmann grade complete recovery rate was significantly higher in the combined treatment group.

Key Conclusion

Combined acupuncture-herbal medicine treatment significantly improved recovery rate and recovery speed in acute facial palsy patients.

RCT Neurological Disorders

Peripheral Blood Flow Improvement Effect of Danggwisayeokgaosuyusaenggang-tang in Women with Cold Hypersensitivity

Lee EJ, Song YK, Ito S, et al.

Journal of Ethnopharmacology (2023)

80 subjects Participants
2.3°C Finger Temperature Rise
p<0.001 Statistical Significance

Danggwisayeokgaosuyusaenggang-tang objectively improves peripheral blood flow in cold hypersensitivity patients.

RCT Neurological Disorders

Peripheral Blood Flow Improvement Effect of Danggwisayeokgaosuyusaenggang-tang in Women with Cold Hypersensitivity

Lee EJ, Song YK, Ito S, et al. Journal of Ethnopharmacology (2023)
80 subjects Participants
2.3°C Finger Temperature Rise
p<0.001 Statistical Significance

Summary

Danggwisayeokgaosuyusaenggang-tang was administered for 8 weeks to 80 women complaining of cold hypersensitivity of hands and feet, and peripheral blood flow was evaluated by infrared thermography and laser Doppler. The treatment group showed significant increases in finger skin temperature and blood flow.

Key Conclusion

Danggwisayeokgaosuyusaenggang-tang objectively improves peripheral blood flow in cold hypersensitivity patients.

Meta-Analysis Neurological Disorders

Effect of Acupuncture Treatment for Tinnitus: A Systematic Review and Meta-Analysis

Kim SW, Jung DH, Wang Y, et al.

Otology & Neurotology (2022)

22 studies Included Studies
1,856 subjects Total Participants
SMD -0.72 Effect Size

Acupuncture treatment shows significant effects on symptom severity reduction and quality of life improvement in tinnitus patients.

Meta-Analysis Neurological Disorders

Effect of Acupuncture Treatment for Tinnitus: A Systematic Review and Meta-Analysis

Kim SW, Jung DH, Wang Y, et al. Otology & Neurotology (2022)
22 studies Included Studies
1,856 subjects Total Participants
SMD -0.72 Effect Size

Summary

A meta-analysis of 22 RCTs (total 1,856 subjects) evaluating the effect of acupuncture treatment in tinnitus patients. The acupuncture treatment group showed significant improvement in THI and VAS scores compared with the control group.

Key Conclusion

Acupuncture treatment shows significant effects on symptom severity reduction and quality of life improvement in tinnitus patients.

RCT Neurological Disorders

Comparison of Effects of Acupuncture Treatment and Regular Analgesics for Tension Headache: An RCT

Choi JY, Baek HJ, Lee MK, et al.

Cephalalgia (2023)

150 subjects Participants
62% Headache Days Reduction
8 weeks Treatment Period

Acupuncture treatment is more effective than analgesics for chronic tension headache management with fewer side effects.

RCT Neurological Disorders

Comparison of Effects of Acupuncture Treatment and Regular Analgesics for Tension Headache: An RCT

Choi JY, Baek HJ, Lee MK, et al. Cephalalgia (2023)
150 subjects Participants
62% Headache Days Reduction
8 weeks Treatment Period

Summary

One hundred fifty patients with chronic tension headache were randomly assigned to acupuncture treatment and acetaminophen groups and compared for 8 weeks. The acupuncture treatment group was significantly superior in headache days and VAS scores.

Key Conclusion

Acupuncture treatment is more effective than analgesics for chronic tension headache management with fewer side effects.

Cohort Study Neurological Disorders

Effect of Banhabaekchulcheonma-tang on Dizziness: A Prospective Cohort Study

Yoo JH, Nam ES, et al.

BMC Complementary Medicine and Therapies (2024)

120 subjects Participants
55% Attack Frequency Reduction
6 months Follow-up Period

Banhabaekchulcheonma-tang can significantly reduce symptom frequency and severity of chronic dizziness.

Cohort Study Neurological Disorders

Effect of Banhabaekchulcheonma-tang on Dizziness: A Prospective Cohort Study

Yoo JH, Nam ES, et al. BMC Complementary Medicine and Therapies (2024)
120 subjects Participants
55% Attack Frequency Reduction
6 months Follow-up Period

Summary

A cohort study following 120 chronic dizziness patients for 6 months, divided into Banhabaekchulcheonma-tang administration and non-administration groups. The herbal medicine administration group showed significant decreases in DHI scores and dizziness attack frequency.

Key Conclusion

Banhabaekchulcheonma-tang can significantly reduce symptom frequency and severity of chronic dizziness.