금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
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Total 1642 papers

Cohort Study Mental Health

Korean Medicine Health Management Utilization and Mental Health in Academically Stressed College Students: A Cohort Study

Yang SB, Kim SH, Lee JA, et al.

BMC Psychiatry (2024)

400 patients Participants
33% Depression reduction
1 year Follow-up period

Korean medicine health management is effective for maintaining mental health and managing academic stress in college students.

Cohort Study Mental Health

Korean Medicine Health Management Utilization and Mental Health in Academically Stressed College Students: A Cohort Study

Yang SB, Kim SH, Lee JA, et al. BMC Psychiatry (2024)
400 patients Participants
33% Depression reduction
1 year Follow-up period

Summary

Four hundred college students were followed for one year, divided into Korean medicine health management users and non-users. Users showed significantly lower PHQ-9 (-33%), GAD-7 (-29%), and academic stress (-25%).

Key Conclusion

Korean medicine health management is effective for maintaining mental health and managing academic stress in college students.

Before-After Mental Health

Pre-Post Comparison Study of Auricular Acupuncture for Nocturnal Anxiety Attacks

Moon SJ, Park JY, Han SH, et al.

Journal of Anxiety Disorders (2024)

71% Attack frequency reduction
45 patients Participants
Sleep improved Additional benefit

Auricular acupuncture effectively reduces the frequency and intensity of nocturnal anxiety attacks.

Before-After Mental Health

Pre-Post Comparison Study of Auricular Acupuncture for Nocturnal Anxiety Attacks

Moon SJ, Park JY, Han SH, et al. Journal of Anxiety Disorders (2024)
71% Attack frequency reduction
45 patients Participants
Sleep improved Additional benefit

Summary

Auricular acupuncture (Shenmen, Heart point, Sympathetic point) was applied to 45 patients with nocturnal anxiety attacks for 6 weeks. Nocturnal attack frequency decreased from 4.1 to 1.2 per week and sleep efficiency improved.

Key Conclusion

Auricular acupuncture effectively reduces the frequency and intensity of nocturnal anxiety attacks.

Cohort Study ENT Disorders

Effect of Jaeumganghwa-tang for Menopausal Women with Xerostomia: A Cohort Study

Moon JH, Yeo JH, Ahn CB, et al.

Menopause (2023)

0.21 mL/min Salivary Flow Increase
58% Oral Dryness VAS Reduction
78 subjects Participants

Jaeumganghwa-tang is an effective herbal medicine that simultaneously improves xerostomia and overall quality of life in menopausal women.

Cohort Study ENT Disorders

Effect of Jaeumganghwa-tang for Menopausal Women with Xerostomia: A Cohort Study

Moon JH, Yeo JH, Ahn CB, et al. Menopause (2023)
0.21 mL/min Salivary Flow Increase
58% Oral Dryness VAS Reduction
78 subjects Participants

Summary

Seventy-eight menopausal women with xerostomia received Jaeumganghwa-tang for 12 weeks, with salivary flow rate, oral dryness VAS, and menopausal quality of life (MENQOL) measured. Unstimulated whole salivary flow rate increased by an average of 0.21 mL/min, with oral dryness VAS decreasing by 58% and MENQOL also significantly improving.

Key Conclusion

Jaeumganghwa-tang is an effective herbal medicine that simultaneously improves xerostomia and overall quality of life in menopausal women.

Narrative Review ENT Disorders

Effect of Korean Medicine Combined Treatment for Chronic Cough Accompanying Laryngopharyngeal Reflux: A Narrative Review

Han CH, Jung TY, Kim MR, et al.

Cough (2023)

14 papers Reviewed Papers
63% Cough Frequency Reduction
2 formulas Major Herbal Prescriptions

Korean medicine combined treatment provides multifaceted approach for effective symptom control of chronic cough related to laryngopharyngeal reflux.

Narrative Review ENT Disorders

Effect of Korean Medicine Combined Treatment for Chronic Cough Accompanying Laryngopharyngeal Reflux: A Narrative Review

Han CH, Jung TY, Kim MR, et al. Cough (2023)
14 papers Reviewed Papers
63% Cough Frequency Reduction
2 formulas Major Herbal Prescriptions

Summary

Fourteen articles on Korean medicine treatment (combined herbal medicine, acupuncture, lifestyle guidance) for chronic cough accompanying laryngopharyngeal reflux were narratively reviewed. Herbal medicines such as Banhahubak-tang and Banhasasim-tang and acupuncture at Tiantu (CV22) and Taiyuan (LU9) were most frequently used, with cough frequency reduction averaging 63%.

Key Conclusion

Korean medicine combined treatment provides multifaceted approach for effective symptom control of chronic cough related to laryngopharyngeal reflux.

Cross-Sectional ENT Disorders

Immunological Effect of Placental Extract Pharmacopuncture for Allergic Rhinitis: A Cross-Sectional Study

Pyo JH, Shin SY, Lee EM, et al.

Allergy (2024)

31% IgE Reduction Rate
49% TNSS Improvement
86 subjects Participants

Placental extract pharmacopuncture demonstrates simultaneous effects on immunological modulation and clinical symptom improvement in allergic rhinitis.

Cross-Sectional ENT Disorders

Immunological Effect of Placental Extract Pharmacopuncture for Allergic Rhinitis: A Cross-Sectional Study

Pyo JH, Shin SY, Lee EM, et al. Allergy (2024)
31% IgE Reduction Rate
49% TNSS Improvement
86 subjects Participants

Summary

Eighty-six patients with allergic rhinitis received placental extract pharmacopuncture at Yingxiang (LI20) and Shangxing (GV23) twice weekly for 8 weeks, with serum immune markers analyzed. Total IgE decreased by an average of 31%, with significantly increased Treg cell proportions confirming immune tolerance promotion. TNSS also improved by 49%.

Key Conclusion

Placental extract pharmacopuncture demonstrates simultaneous effects on immunological modulation and clinical symptom improvement in allergic rhinitis.

Case Study ENT Disorders

Effect of Acupuncture for Headache Accompanying Chronic Septal Deviation: 8 Case Reports

Yoon MH, Lee JE, Byun SH, et al.

한방안이비인후피부과학회지 (2024)

4.7 points Headache VAS Reduction
5.2→1.8 Weekly Headache Frequency
8 cases Case Number

Acupuncture is a conservative treatment method that significantly reduces frequency and intensity of septal deviation-related headache.

Case Study ENT Disorders

Effect of Acupuncture for Headache Accompanying Chronic Septal Deviation: 8 Case Reports

Yoon MH, Lee JE, Byun SH, et al. 한방안이비인후피부과학회지 (2024)
4.7 points Headache VAS Reduction
5.2→1.8 Weekly Headache Frequency
8 cases Case Number

Summary

Eight patients with chronic headache accompanying septal deviation received acupuncture at Hegu (LI4), Shangxing (GV23), and Yingxiang (LI20) twice weekly for 8 weeks. Headache VAS decreased by an average of 4.7 points, with weekly nasal obstruction-related headache frequency reduced from 5.2 to 1.8 episodes.

Key Conclusion

Acupuncture is a conservative treatment method that significantly reduces frequency and intensity of septal deviation-related headache.

Systematic Review ENT Disorders

Effect of Acupuncture for Pain Management After Tonsillectomy: A Systematic Review

Go GY, Shin WC, Koo BS, et al.

Laryngoscope (2023)

34% Analgesic Reduction
1.2 days Diet Initiation Reduction
8 studies Reviewed Studies

Acupuncture is a complementary method for post-tonsillectomy pain management that reduces analgesic use and promotes recovery.

Systematic Review ENT Disorders

Effect of Acupuncture for Pain Management After Tonsillectomy: A Systematic Review

Go GY, Shin WC, Koo BS, et al. Laryngoscope (2023)
34% Analgesic Reduction
1.2 days Diet Initiation Reduction
8 studies Reviewed Studies

Summary

Eight RCTs evaluating acupuncture effects for post-tonsillectomy pain were systematically reviewed. The acupuncture combination group demonstrated an average 34% reduction in postoperative analgesic use, with the time to start oral intake advanced by an average of 1.2 days.

Key Conclusion

Acupuncture is a complementary method for post-tonsillectomy pain management that reduces analgesic use and promotes recovery.

Cohort Study ENT Disorders

Long-term Prognosis of Modified Taeksa-tang for Meniere's Disease: A 5-Year Follow-up Cohort Study

Noh SH, Kwak HY, Jang SG, et al.

Otology & Neurotology (2023)

62% Complete Vertigo Remission
71% Hearing Preservation
5 years Follow-up Period

Modified Taeksa-tang is effective for long-term vertigo control and hearing preservation in Meniere's disease.

Cohort Study ENT Disorders

Long-term Prognosis of Modified Taeksa-tang for Meniere's Disease: A 5-Year Follow-up Cohort Study

Noh SH, Kwak HY, Jang SG, et al. Otology & Neurotology (2023)
62% Complete Vertigo Remission
71% Hearing Preservation
5 years Follow-up Period

Summary

Eighty-nine patients with Meniere's disease received modified Taeksa-tang for 6 months and were followed for 5 years. Complete remission rate of vertigo attacks was 62%, with 71% experiencing no hearing deterioration—a significantly superior long-term prognosis compared with natural history.

Key Conclusion

Modified Taeksa-tang is effective for long-term vertigo control and hearing preservation in Meniere's disease.

RCT ENT Disorders

Comparison of Frequency-Specific Effects of Electroacupuncture (2 Hz/100 Hz Alternating) for Tinnitus: A Randomized Controlled Trial

Im JH, Choi GH, Lee TY, et al.

Neuromodulation (2024)

48% THI Reduction (Alternating)
96 subjects Participants
6 weeks Treatment Period

2/100 Hz alternating electroacupuncture demonstrates superior efficacy over single-frequency stimulation in tinnitus symptom alleviation and brain activity normalization.

RCT ENT Disorders

Comparison of Frequency-Specific Effects of Electroacupuncture (2 Hz/100 Hz Alternating) for Tinnitus: A Randomized Controlled Trial

Im JH, Choi GH, Lee TY, et al. Neuromodulation (2024)
48% THI Reduction (Alternating)
96 subjects Participants
6 weeks Treatment Period

Summary

Ninety-six patients with chronic tinnitus were assigned to 2 Hz electroacupuncture, 100 Hz electroacupuncture, or 2/100 Hz alternating groups for 6 weeks of treatment. The 2/100 Hz alternating group demonstrated a 48% reduction in THI, significantly superior to the 2 Hz (31%) and 100 Hz (35%) groups. Auditory cortex hyperactivity on fMRI also showed the greatest reduction in the alternating group.

Key Conclusion

2/100 Hz alternating electroacupuncture demonstrates superior efficacy over single-frequency stimulation in tinnitus symptom alleviation and brain activity normalization.

Case Study Men's Health / Urology

Effect of Taeumjowi-tang on Metabolic Indicator Improvement for Visceral Fat-Type Male Obesity: A Case Study

김하준, 이채원, 정태욱, et al.

Metabolism (2023)

31.4 cm² Visceral Fat Reduction
10 cases Number of Cases
12 weeks Treatment Period

Taeumjowi-tang is an effective and safe treatment for visceral fat reduction and metabolic indicator improvement in visceral fat-type male obesity.

Case Study Men's Health / Urology

Effect of Taeumjowi-tang on Metabolic Indicator Improvement for Visceral Fat-Type Male Obesity: A Case Study

김하준, 이채원, 정태욱, et al. Metabolism (2023)
31.4 cm² Visceral Fat Reduction
10 cases Number of Cases
12 weeks Treatment Period

Summary

A case study on Taeumjowi-tang treatment in 10 male patients with visceral fat-type obesity (CT visceral fat area ≥100 cm²). After 12 weeks of administration, visceral fat area decreased by an average of 31.4 cm², and metabolic indicators including fasting blood glucose, HbA1c, triglycerides, and LDL-C also improved significantly. Liver function indicators (AST/ALT) remained within normal ranges.

Key Conclusion

Taeumjowi-tang is an effective and safe treatment for visceral fat reduction and metabolic indicator improvement in visceral fat-type male obesity.

Before-After Men's Health / Urology

Effect of Modified Dojeok-san on Residual Symptoms After Urethritis: A Pre-Post Comparison Study

안성호, 배진혁, 홍유진, et al.

대한한방내과학회지 (2024)

73.1% VAS Reduction Rate
36 subjects Number of Subjects
6 weeks Treatment Period

Modified Dojeok-san is effective for alleviating residual urethral symptoms after antibiotic treatment, with a mechanism through local inflammatory response suppression confirmed.

Before-After Men's Health / Urology

Effect of Modified Dojeok-san on Residual Symptoms After Urethritis: A Pre-Post Comparison Study

안성호, 배진혁, 홍유진, et al. 대한한방내과학회지 (2024)
73.1% VAS Reduction Rate
36 subjects Number of Subjects
6 weeks Treatment Period

Summary

A pre-post comparison study analyzing the effect of modified Dojeok-san in 36 men with persistent urethral discomfort after antibiotic treatment. After 6 weeks of administration, urethral burning VAS decreased from an average of 6.7 to 1.8, and urinary frequency and residual urine sensation also improved significantly. Urinary cytokine (IL-8, IL-1β) levels also decreased.

Key Conclusion

Modified Dojeok-san is effective for alleviating residual urethral symptoms after antibiotic treatment, with a mechanism through local inflammatory response suppression confirmed.

Cross-Sectional Men's Health / Urology

Antibacterial and Anti-Inflammatory Effect of Yongdamsagan-tang on Male Genital Infections: A Cross-Sectional Study

차현석, 김진우, 문승재, et al.

Journal of Microbiology and Biotechnology (2023)

3.8 days Treatment Period Shortened
48 subjects Number of Subjects
p=0.008 Statistical Significance

Yongdamsagan-tang enhances anti-inflammatory effects as an antibiotic adjunct treatment for male genital infections and shortens treatment duration.

Cross-Sectional Men's Health / Urology

Antibacterial and Anti-Inflammatory Effect of Yongdamsagan-tang on Male Genital Infections: A Cross-Sectional Study

차현석, 김진우, 문승재, et al. Journal of Microbiology and Biotechnology (2023)
3.8 days Treatment Period Shortened
48 subjects Number of Subjects
p=0.008 Statistical Significance

Summary

A cross-sectional study analyzing the antibacterial and anti-inflammatory effect of Yongdamsagan-tang in 48 male patients with genital infections (epididymitis, seminal vesiculitis). With antibiotic combination, the Yongdamsagan-tang addition group showed faster decreases in CRP and semen leukocyte levels, and symptom resolution period was shortened by an average of 3.8 days.

Key Conclusion

Yongdamsagan-tang enhances anti-inflammatory effects as an antibiotic adjunct treatment for male genital infections and shortens treatment duration.