금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
🔍

Total 1642 papers

RCT Mental Health

Effects of Electroacupuncture on Adults with Attention Deficit: A Randomized Controlled Trial

Yoon HJ, Lee KH, Shin JH, et al.

ADHD Attention Deficit and Hyperactivity Disorders (2023)

38% Inattention reduction
65 patients Participants
Executive function improved Stroop improvement

Electroacupuncture is effective in improving inattention symptoms and executive function in adult ADHD.

RCT Mental Health

Effects of Electroacupuncture on Adults with Attention Deficit: A Randomized Controlled Trial

Yoon HJ, Lee KH, Shin JH, et al. ADHD Attention Deficit and Hyperactivity Disorders (2023)
38% Inattention reduction
65 patients Participants
Executive function improved Stroop improvement

Summary

Sixty-five adult ADHD patients were compared between electroacupuncture and sham acupuncture groups for 8 weeks. The electroacupuncture group showed a 38% reduction in CAARS inattention scores and improved executive function (Stroop test).

Key Conclusion

Electroacupuncture is effective in improving inattention symptoms and executive function in adult ADHD.

Cohort Study Pediatric / Adolescent Care

Cohort Study of Korean Medicine Intervention for Children with School Refusal

Go JH, Kim CH, Park HJ, et al.

School Psychology International (2024)

87% Attendance improvement
45 patients Participants
Anxiety reduced Emotional improvement

Korean medicine intervention is effective in improving attendance and reducing anxiety in children with school refusal.

Cohort Study Pediatric / Adolescent Care

Cohort Study of Korean Medicine Intervention for Children with School Refusal

Go JH, Kim CH, Park HJ, et al. School Psychology International (2024)
87% Attendance improvement
45 patients Participants
Anxiety reduced Emotional improvement

Summary

Forty-five children with school refusal were followed for 12 weeks, divided into a Korean medicine intervention group (herbal medicine + acupuncture + parent counseling) and a waitlist group. Attendance improved from 52% to 87% and anxiety scores decreased in the intervention group.

Key Conclusion

Korean medicine intervention is effective in improving attendance and reducing anxiety in children with school refusal.

RCT ENT Disorders

Comparison of Frequency-Specific Effects of Electroacupuncture (2 Hz/100 Hz Alternating) for Tinnitus: A Randomized Controlled Trial

Im JH, Choi GH, Lee TY, et al.

Neuromodulation (2024)

48% THI Reduction (Alternating)
96 subjects Participants
6 weeks Treatment Period

2/100 Hz alternating electroacupuncture demonstrates superior efficacy over single-frequency stimulation in tinnitus symptom alleviation and brain activity normalization.

RCT ENT Disorders

Comparison of Frequency-Specific Effects of Electroacupuncture (2 Hz/100 Hz Alternating) for Tinnitus: A Randomized Controlled Trial

Im JH, Choi GH, Lee TY, et al. Neuromodulation (2024)
48% THI Reduction (Alternating)
96 subjects Participants
6 weeks Treatment Period

Summary

Ninety-six patients with chronic tinnitus were assigned to 2 Hz electroacupuncture, 100 Hz electroacupuncture, or 2/100 Hz alternating groups for 6 weeks of treatment. The 2/100 Hz alternating group demonstrated a 48% reduction in THI, significantly superior to the 2 Hz (31%) and 100 Hz (35%) groups. Auditory cortex hyperactivity on fMRI also showed the greatest reduction in the alternating group.

Key Conclusion

2/100 Hz alternating electroacupuncture demonstrates superior efficacy over single-frequency stimulation in tinnitus symptom alleviation and brain activity normalization.

Cohort Study ENT Disorders

Long-term Prognosis of Modified Taeksa-tang for Meniere's Disease: A 5-Year Follow-up Cohort Study

Noh SH, Kwak HY, Jang SG, et al.

Otology & Neurotology (2023)

62% Complete Vertigo Remission
71% Hearing Preservation
5 years Follow-up Period

Modified Taeksa-tang is effective for long-term vertigo control and hearing preservation in Meniere's disease.

Cohort Study ENT Disorders

Long-term Prognosis of Modified Taeksa-tang for Meniere's Disease: A 5-Year Follow-up Cohort Study

Noh SH, Kwak HY, Jang SG, et al. Otology & Neurotology (2023)
62% Complete Vertigo Remission
71% Hearing Preservation
5 years Follow-up Period

Summary

Eighty-nine patients with Meniere's disease received modified Taeksa-tang for 6 months and were followed for 5 years. Complete remission rate of vertigo attacks was 62%, with 71% experiencing no hearing deterioration—a significantly superior long-term prognosis compared with natural history.

Key Conclusion

Modified Taeksa-tang is effective for long-term vertigo control and hearing preservation in Meniere's disease.

Systematic Review ENT Disorders

Effect of Acupuncture for Pain Management After Tonsillectomy: A Systematic Review

Go GY, Shin WC, Koo BS, et al.

Laryngoscope (2023)

34% Analgesic Reduction
1.2 days Diet Initiation Reduction
8 studies Reviewed Studies

Acupuncture is a complementary method for post-tonsillectomy pain management that reduces analgesic use and promotes recovery.

Systematic Review ENT Disorders

Effect of Acupuncture for Pain Management After Tonsillectomy: A Systematic Review

Go GY, Shin WC, Koo BS, et al. Laryngoscope (2023)
34% Analgesic Reduction
1.2 days Diet Initiation Reduction
8 studies Reviewed Studies

Summary

Eight RCTs evaluating acupuncture effects for post-tonsillectomy pain were systematically reviewed. The acupuncture combination group demonstrated an average 34% reduction in postoperative analgesic use, with the time to start oral intake advanced by an average of 1.2 days.

Key Conclusion

Acupuncture is a complementary method for post-tonsillectomy pain management that reduces analgesic use and promotes recovery.

Case Study ENT Disorders

Effect of Acupuncture for Headache Accompanying Chronic Septal Deviation: 8 Case Reports

Yoon MH, Lee JE, Byun SH, et al.

한방안이비인후피부과학회지 (2024)

4.7 points Headache VAS Reduction
5.2→1.8 Weekly Headache Frequency
8 cases Case Number

Acupuncture is a conservative treatment method that significantly reduces frequency and intensity of septal deviation-related headache.

Case Study ENT Disorders

Effect of Acupuncture for Headache Accompanying Chronic Septal Deviation: 8 Case Reports

Yoon MH, Lee JE, Byun SH, et al. 한방안이비인후피부과학회지 (2024)
4.7 points Headache VAS Reduction
5.2→1.8 Weekly Headache Frequency
8 cases Case Number

Summary

Eight patients with chronic headache accompanying septal deviation received acupuncture at Hegu (LI4), Shangxing (GV23), and Yingxiang (LI20) twice weekly for 8 weeks. Headache VAS decreased by an average of 4.7 points, with weekly nasal obstruction-related headache frequency reduced from 5.2 to 1.8 episodes.

Key Conclusion

Acupuncture is a conservative treatment method that significantly reduces frequency and intensity of septal deviation-related headache.

Cross-Sectional ENT Disorders

Immunological Effect of Placental Extract Pharmacopuncture for Allergic Rhinitis: A Cross-Sectional Study

Pyo JH, Shin SY, Lee EM, et al.

Allergy (2024)

31% IgE Reduction Rate
49% TNSS Improvement
86 subjects Participants

Placental extract pharmacopuncture demonstrates simultaneous effects on immunological modulation and clinical symptom improvement in allergic rhinitis.

Cross-Sectional ENT Disorders

Immunological Effect of Placental Extract Pharmacopuncture for Allergic Rhinitis: A Cross-Sectional Study

Pyo JH, Shin SY, Lee EM, et al. Allergy (2024)
31% IgE Reduction Rate
49% TNSS Improvement
86 subjects Participants

Summary

Eighty-six patients with allergic rhinitis received placental extract pharmacopuncture at Yingxiang (LI20) and Shangxing (GV23) twice weekly for 8 weeks, with serum immune markers analyzed. Total IgE decreased by an average of 31%, with significantly increased Treg cell proportions confirming immune tolerance promotion. TNSS also improved by 49%.

Key Conclusion

Placental extract pharmacopuncture demonstrates simultaneous effects on immunological modulation and clinical symptom improvement in allergic rhinitis.

Narrative Review ENT Disorders

Effect of Korean Medicine Combined Treatment for Chronic Cough Accompanying Laryngopharyngeal Reflux: A Narrative Review

Han CH, Jung TY, Kim MR, et al.

Cough (2023)

14 papers Reviewed Papers
63% Cough Frequency Reduction
2 formulas Major Herbal Prescriptions

Korean medicine combined treatment provides multifaceted approach for effective symptom control of chronic cough related to laryngopharyngeal reflux.

Narrative Review ENT Disorders

Effect of Korean Medicine Combined Treatment for Chronic Cough Accompanying Laryngopharyngeal Reflux: A Narrative Review

Han CH, Jung TY, Kim MR, et al. Cough (2023)
14 papers Reviewed Papers
63% Cough Frequency Reduction
2 formulas Major Herbal Prescriptions

Summary

Fourteen articles on Korean medicine treatment (combined herbal medicine, acupuncture, lifestyle guidance) for chronic cough accompanying laryngopharyngeal reflux were narratively reviewed. Herbal medicines such as Banhahubak-tang and Banhasasim-tang and acupuncture at Tiantu (CV22) and Taiyuan (LU9) were most frequently used, with cough frequency reduction averaging 63%.

Key Conclusion

Korean medicine combined treatment provides multifaceted approach for effective symptom control of chronic cough related to laryngopharyngeal reflux.

Cohort Study ENT Disorders

Effect of Jaeumganghwa-tang for Menopausal Women with Xerostomia: A Cohort Study

Moon JH, Yeo JH, Ahn CB, et al.

Menopause (2023)

0.21 mL/min Salivary Flow Increase
58% Oral Dryness VAS Reduction
78 subjects Participants

Jaeumganghwa-tang is an effective herbal medicine that simultaneously improves xerostomia and overall quality of life in menopausal women.

Cohort Study ENT Disorders

Effect of Jaeumganghwa-tang for Menopausal Women with Xerostomia: A Cohort Study

Moon JH, Yeo JH, Ahn CB, et al. Menopause (2023)
0.21 mL/min Salivary Flow Increase
58% Oral Dryness VAS Reduction
78 subjects Participants

Summary

Seventy-eight menopausal women with xerostomia received Jaeumganghwa-tang for 12 weeks, with salivary flow rate, oral dryness VAS, and menopausal quality of life (MENQOL) measured. Unstimulated whole salivary flow rate increased by an average of 0.21 mL/min, with oral dryness VAS decreasing by 58% and MENQOL also significantly improving.

Key Conclusion

Jaeumganghwa-tang is an effective herbal medicine that simultaneously improves xerostomia and overall quality of life in menopausal women.

Before-After Men's Health / Urology

Effect of Ugwiyin on Energy Metabolism Improvement in Vitality Decline and Yang Deficiency: A Pre-Post Comparison Study

정승호, 최원석, 양지훈, et al.

Journal of Ginseng Research (2024)

61.2% Fatigue Reduction Rate
62 subjects Number of Subjects
p<0.001 Statistical Significance

Ugwiyin activates cellular energy metabolism in yang deficiency men and significantly improves subjective fatigue.

Before-After Men's Health / Urology

Effect of Ugwiyin on Energy Metabolism Improvement in Vitality Decline and Yang Deficiency: A Pre-Post Comparison Study

정승호, 최원석, 양지훈, et al. Journal of Ginseng Research (2024)
61.2% Fatigue Reduction Rate
62 subjects Number of Subjects
p<0.001 Statistical Significance

Summary

A pre-post comparison study analyzing the effect of Ugwiyin on energy metabolism improvement in 62 men complaining of vitality decline and yang deficiency. After 8 weeks of administration, blood CoQ10 and ATP production capacity increased significantly, and thyroid function indicators (fT3, fT4) also increased within normal ranges. VAS fatigue scores decreased by an average of 61.2%.

Key Conclusion

Ugwiyin activates cellular energy metabolism in yang deficiency men and significantly improves subjective fatigue.

Narrative Review Men's Health / Urology

Semen Parameter Improvement with Korean Medicine Treatment for Varicocele-Associated Male Infertility: A Narrative Literature Review

서영민, 김도형, 이준석, et al.

Reproductive BioMedicine Online (2024)

28 studies Analyzed Studies
34.5% Natural Pregnancy Rate (Herbal Group)
10 years Analysis Period

Korean medicine treatment is promising as non-surgical management of varicocele-associated male infertility and as adjunctive treatment for surgery, and large-scale clinical trials are needed.

Narrative Review Men's Health / Urology

Semen Parameter Improvement with Korean Medicine Treatment for Varicocele-Associated Male Infertility: A Narrative Literature Review

서영민, 김도형, 이준석, et al. Reproductive BioMedicine Online (2024)
28 studies Analyzed Studies
34.5% Natural Pregnancy Rate (Herbal Group)
10 years Analysis Period

Summary

A narrative literature review comprehensively analyzing Korean medicine treatment research for varicocele-associated male infertility. Analysis of 28 studies confirmed that Gyejibongnyong-hwan-based herbal medicine was effective for improving varicocele grade and semen parameters, and herbal medicine combination before and after surgery additionally improved pregnancy rates.

Key Conclusion

Korean medicine treatment is promising as non-surgical management of varicocele-associated male infertility and as adjunctive treatment for surgery, and large-scale clinical trials are needed.

Systematic Review Men's Health / Urology

Analgesic Effect of Combined Electroacupuncture and Moxibustion Treatment for Testicular Pain: A Systematic Review

김성준, 박현우, 장태호, et al.

Pain Medicine (2023)

3.4 points NRS Pain Reduction
312 subjects Total Subjects
8 studies Included Studies

Combined electroacupuncture-moxibustion treatment is an effective non-pharmacological analgesic therapy for chronic testicular pain and contributes to alleviating neuropathic pain mechanisms.

Systematic Review Men's Health / Urology

Analgesic Effect of Combined Electroacupuncture and Moxibustion Treatment for Testicular Pain: A Systematic Review

김성준, 박현우, 장태호, et al. Pain Medicine (2023)
3.4 points NRS Pain Reduction
312 subjects Total Subjects
8 studies Included Studies

Summary

A systematic review analyzing the analgesic effect of combined electroacupuncture and moxibustion treatment in chronic testicular pain patients. Eight clinical trials (total 312 subjects) were included, and the combined electroacupuncture-moxibustion group showed an average NRS pain score reduction of 3.4 points, with significantly reduced analgesic usage. Daedun and Gwirae acupoints were the main selected points.

Key Conclusion

Combined electroacupuncture-moxibustion treatment is an effective non-pharmacological analgesic therapy for chronic testicular pain and contributes to alleviating neuropathic pain mechanisms.