금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
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Total 1642 papers

Systematic Review Mental Health

Systematic Review of Acupuncture for Cortisol Dysregulation in Chronic Stress

Cha YR, Lee DH, Kang BK, et al.

Psychoneuroendocrinology (2023)

22 studies Analyzed papers
Cortisol normalized HPA axis modulation
DHEA-S increased Stress recovery

Acupuncture improves neuroendocrine dysregulation in chronic stress through HPA axis modulation.

Systematic Review Mental Health

Systematic Review of Acupuncture for Cortisol Dysregulation in Chronic Stress

Cha YR, Lee DH, Kang BK, et al. Psychoneuroendocrinology (2023)
22 studies Analyzed papers
Cortisol normalized HPA axis modulation
DHEA-S increased Stress recovery

Summary

Twenty-two studies evaluating acupuncture for HPA axis dysregulation in chronic stress were systematically reviewed. Acupuncture showed significant effects in normalizing cortisol diurnal variation and increasing DHEA-S.

Key Conclusion

Acupuncture improves neuroendocrine dysregulation in chronic stress through HPA axis modulation.

Narrative Review Mental Health

Korean Medicine for Depression Comorbid with Alcohol Dependence: A Narrative Review

Ryu BH, Yoo TW, Park EJ, et al.

Addictive Behaviors (2023)

15 studies Reviewed papers
Craving reduced Dependence management
Depression reduced Emotional improvement

Korean medicine is a useful adjunctive therapy for the integrated management of depression comorbid with alcohol dependence.

Narrative Review Mental Health

Korean Medicine for Depression Comorbid with Alcohol Dependence: A Narrative Review

Ryu BH, Yoo TW, Park EJ, et al. Addictive Behaviors (2023)
15 studies Reviewed papers
Craving reduced Dependence management
Depression reduced Emotional improvement

Summary

Fifteen studies on Korean medicine treatment for patients with alcohol dependence comorbid with depression were reviewed. Combination of herbal medicine (Galgeun-tang, Hwangryeonhaedok-tang) with acupuncture showed efficacy in reducing alcohol craving and depressive symptoms.

Key Conclusion

Korean medicine is a useful adjunctive therapy for the integrated management of depression comorbid with alcohol dependence.

RCT Mental Health

Randomized Controlled Trial of Acupuncture Treatment for COVID-19 Sequelae Brain Fog

Lee AR, Park SJ, Kim GH, et al.

Journal of Neurology (2023)

32% TMT-B Improvement
80 subjects Participants
8 weeks Treatment Period

Acupuncture treatment is effective for cognitive function recovery in COVID-19 sequelae brain fog.

RCT Mental Health

Randomized Controlled Trial of Acupuncture Treatment for COVID-19 Sequelae Brain Fog

Lee AR, Park SJ, Kim GH, et al. Journal of Neurology (2023)
32% TMT-B Improvement
80 subjects Participants
8 weeks Treatment Period

Summary

Eighty patients complaining of cognitive decline (brain fog) after COVID-19 were compared between acupuncture treatment and waiting list groups for 8 weeks. TMT-B performance time was shortened by 32% and subjective cognitive function significantly improved in the acupuncture group.

Key Conclusion

Acupuncture treatment is effective for cognitive function recovery in COVID-19 sequelae brain fog.

Before-After Mental Health

Sleep Architecture Changes with Ondam-tang in Chronic Insomnia Patients: A Pre-Post Comparison Study

Cho WS, Kwon CY, Song MY, et al.

Sleep and Breathing (2024)

50% Latency Shortened
REM↑ Sleep Architecture Improvement
50 subjects Participants

Ondam-tang is effective for sleep latency shortening and REM sleep normalization.

Before-After Mental Health

Sleep Architecture Changes with Ondam-tang in Chronic Insomnia Patients: A Pre-Post Comparison Study

Cho WS, Kwon CY, Song MY, et al. Sleep and Breathing (2024)
50% Latency Shortened
REM↑ Sleep Architecture Improvement
50 subjects Participants

Summary

Ondam-tang was administered for 8 weeks to 50 chronic insomnia patients, and sleep architecture was evaluated by PSG. Sleep latency was shortened from 28 minutes to 14 minutes, and REM sleep proportion increased.

Key Conclusion

Ondam-tang is effective for sleep latency shortening and REM sleep normalization.

Case Study Pediatric / Adolescent Care

Korean Medicine Intervention Case Series for Stress in School-Maladjusted Adolescents

Lee SG, Bae HS, Jung WS, et al.

Adolescent Health, Medicine and Therapeutics (2023)

12 cases Number of Cases
43% Stress↓
Adaptability↑ School Life Improvement

Korean medicine intervention is effective for stress management and adaptability improvement in school-maladjusted adolescents.

Case Study Pediatric / Adolescent Care

Korean Medicine Intervention Case Series for Stress in School-Maladjusted Adolescents

Lee SG, Bae HS, Jung WS, et al. Adolescent Health, Medicine and Therapeutics (2023)
12 cases Number of Cases
43% Stress↓
Adaptability↑ School Life Improvement

Summary

Herbal medicine + auricular acupuncture + counseling were applied for 10 weeks to 12 adolescents showing school maladjustment. PSS stress (-43%) and school adaptation scale (+35%) all improved.

Key Conclusion

Korean medicine intervention is effective for stress management and adaptability improvement in school-maladjusted adolescents.

RCT Mental Health

Effect of Combined Acupuncture Treatment and Cognitive Training for Elderly with Cognitive Decline: A Randomized Controlled Trial

Oh SE, Kim YS, Cho AR, et al.

Neuropsychology (2024)

MoCA +3.1 Cognitive function↑
90 subjects Participants
16 weeks Treatment Period

The combination of acupuncture treatment and cognitive training shows synergistic effects on cognitive function improvement in elderly with mild cognitive impairment.

RCT Mental Health

Effect of Combined Acupuncture Treatment and Cognitive Training for Elderly with Cognitive Decline: A Randomized Controlled Trial

Oh SE, Kim YS, Cho AR, et al. Neuropsychology (2024)
MoCA +3.1 Cognitive function↑
90 subjects Participants
16 weeks Treatment Period

Summary

Ninety elderly with mild cognitive impairment were divided into acupuncture + cognitive training and cognitive training alone groups and compared for 16 weeks. MoCA (+3.1 points) and instrumental activities of daily living (K-IADL) significantly improved in the combined group.

Key Conclusion

The combination of acupuncture treatment and cognitive training shows synergistic effects on cognitive function improvement in elderly with mild cognitive impairment.

Cohort Study Women's Health / Infertility

Cohort Study of Moxibustion Treatment for Menopausal Insomnia

Noh HM, Park MJ, Yun YG, et al.

Climacteric (2023)

5.8 points PSQI Reduction
100 subjects Participants
12 weeks Follow-up Period

Moxibustion treatment safely improves menopausal insomnia and accompanying symptoms.

Cohort Study Women's Health / Infertility

Cohort Study of Moxibustion Treatment for Menopausal Insomnia

Noh HM, Park MJ, Yun YG, et al. Climacteric (2023)
5.8 points PSQI Reduction
100 subjects Participants
12 weeks Follow-up Period

Summary

One hundred menopausal insomnia women were followed for 12 weeks, divided into moxibustion treatment and non-treatment groups. PSQI decreased by 5.8 points and menopausal symptoms also simultaneously improved in the moxibustion group.

Key Conclusion

Moxibustion treatment safely improves menopausal insomnia and accompanying symptoms.

Cross-Sectional ENT Disorders

Effect of Thread Embedding Therapy for Facial Nerve Palsy Sequelae: A Cross-Sectional Study

Choi AR, Kim SH, Yoo HR, et al.

Journal of Clinical Medicine (2023)

21 points Sunnybrook Improvement
78% Patient Satisfaction
62 subjects Participants

Thread embedding therapy is an effective Korean medicine procedure for both facial function and aesthetic improvement in facial nerve palsy sequelae.

Cross-Sectional ENT Disorders

Effect of Thread Embedding Therapy for Facial Nerve Palsy Sequelae: A Cross-Sectional Study

Choi AR, Kim SH, Yoo HR, et al. Journal of Clinical Medicine (2023)
21 points Sunnybrook Improvement
78% Patient Satisfaction
62 subjects Participants

Summary

Sixty-two patients with sequelae (synkinesis, facial contracture) persisting more than 3 months after Bell's palsy received thread embedding therapy, with Sunnybrook facial grading and patient satisfaction evaluated. After 8 weeks of treatment, Sunnybrook scores improved by an average of 21 points, with facial symmetry satisfaction reaching 78%.

Key Conclusion

Thread embedding therapy is an effective Korean medicine procedure for both facial function and aesthetic improvement in facial nerve palsy sequelae.

Before-After ENT Disorders

Olfactory Recovery Effect of Tonggyu-tang for Olfactory Dysfunction After Chronic Sinusitis: A Pre-Post Comparison Study

Cho YS, Jung DH, Byun JY, et al.

Chemical Senses (2024)

7.8 points TDI Score Improvement
42% Olfactory Normalization
47 subjects Participants

Tonggyu-tang is an effective herbal treatment that promotes recovery from olfactory dysfunction after chronic sinusitis surgery.

Before-After ENT Disorders

Olfactory Recovery Effect of Tonggyu-tang for Olfactory Dysfunction After Chronic Sinusitis: A Pre-Post Comparison Study

Cho YS, Jung DH, Byun JY, et al. Chemical Senses (2024)
7.8 points TDI Score Improvement
42% Olfactory Normalization
47 subjects Participants

Summary

Forty-seven patients with persistent olfactory dysfunction after chronic sinusitis surgery received Tonggyu-tang for 12 weeks, with pre- and post-treatment KVSS II olfactory testing compared. TDI scores improved by an average of 7.8 points, with 42% reaching normosmia criteria (TDI≥30.5).

Key Conclusion

Tonggyu-tang is an effective herbal treatment that promotes recovery from olfactory dysfunction after chronic sinusitis surgery.

RCT ENT Disorders

Immunomodulatory Effect of Moxibustion at Yingxiang for Allergic Rhinitis: A Randomized Controlled Trial

Son JY, Lee AR, Moon PD, et al.

Immunology Letters (2023)

28% IgE Reduction Rate
54% Symptom Reduction Rate
104 subjects Participants

Moxibustion at Yingxiang simultaneously improves immunological markers and clinical symptoms in allergic rhinitis.

RCT ENT Disorders

Immunomodulatory Effect of Moxibustion at Yingxiang for Allergic Rhinitis: A Randomized Controlled Trial

Son JY, Lee AR, Moon PD, et al. Immunology Letters (2023)
28% IgE Reduction Rate
54% Symptom Reduction Rate
104 subjects Participants

Summary

One hundred four patients with allergic rhinitis were assigned to moxibustion at Yingxiang (LI20) or sham moxibustion control groups for 6 weeks of treatment. The moxibustion group demonstrated an average 28% reduction in serum IgE and improvement in IL-4/IFN-γ ratio toward normalization, with sneezing and rhinorrhea symptoms decreasing by 54%.

Key Conclusion

Moxibustion at Yingxiang simultaneously improves immunological markers and clinical symptoms in allergic rhinitis.

Case Study ENT Disorders

Hearing Recovery Effect of Adjunctive Astragalus Pharmacopuncture for Sudden Sensorineural Hearing Loss: A Case Series

Kang MS, Lee CK, Woo HJ, et al.

Journal of Acupuncture and Meridian Studies (2023)

23.4 dB Hearing Improvement
56% Complete Recovery Rate
18 cases Case Number

Adjunctive Astragalus pharmacopuncture increases hearing recovery rates in sudden sensorineural hearing loss, with effects particularly notable in moderate hearing loss.

Case Study ENT Disorders

Hearing Recovery Effect of Adjunctive Astragalus Pharmacopuncture for Sudden Sensorineural Hearing Loss: A Case Series

Kang MS, Lee CK, Woo HJ, et al. Journal of Acupuncture and Meridian Studies (2023)
23.4 dB Hearing Improvement
56% Complete Recovery Rate
18 cases Case Number

Summary

Eighteen patients with sudden sensorineural hearing loss received adjunctive Astragalus pharmacopuncture at Fengchi, Wangu, and Yifeng three times weekly for 4 weeks alongside steroid treatment. Pure tone audiometry showed an average 23.4 dB improvement, with a 56% complete recovery rate (within 25 dB).

Key Conclusion

Adjunctive Astragalus pharmacopuncture increases hearing recovery rates in sudden sensorineural hearing loss, with effects particularly notable in moderate hearing loss.

Systematic Review Neurological Disorders

Therapeutic Effect of Chuna Manipulation for Cervicogenic Vertigo: A Systematic Review

Hong KE, Choi YB, Shin MS, et al.

Manual Therapy (2024)

46% DHI Reduction Rate
13 studies Reviewed Studies
ROM Improvement Cervical Range of Motion

Chuna manipulation is an effective manual therapy that simultaneously improves vertigo symptoms and cervical function in cervicogenic vertigo.

Systematic Review Neurological Disorders

Therapeutic Effect of Chuna Manipulation for Cervicogenic Vertigo: A Systematic Review

Hong KE, Choi YB, Shin MS, et al. Manual Therapy (2024)
46% DHI Reduction Rate
13 studies Reviewed Studies
ROM Improvement Cervical Range of Motion

Summary

Thirteen clinical studies evaluating chuna manipulation effects for cervicogenic dizziness were systematically reviewed. The chuna manipulation group demonstrated an average 46% reduction in DHI scores, with significant improvement in cervical range of motion (ROM). Effects were maximized when chuna was combined with acupuncture.

Key Conclusion

Chuna manipulation is an effective manual therapy that simultaneously improves vertigo symptoms and cervical function in cervicogenic vertigo.