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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Cohort Study Skin Conditions

Effect of Jaungo for Wound Healing: A Prospective Cohort Study

권순영, 김대한, 이예림, et al.

Wound Repair and Regeneration (2024)

83 patients Cohort size
-5.2 days Healing duration reduction
p=0.008 Scar reduction

Jaungo is an effective Korean medicine topical preparation that promotes skin wound healing and suppresses scar formation.

View Source 2024
Cohort Study Skin Conditions

Effect of Jaungo for Wound Healing: A Prospective Cohort Study

권순영, 김대한, 이예림, et al. Wound Repair and Regeneration (2024)
83 patients Cohort size
-5.2 days Healing duration reduction
p=0.008 Scar reduction

Summary

Eighty-three patients with skin wounds of various etiologies were divided into Jaungo application and silver sulfadiazine cream application groups, and wound healing process was observed. The Jaungo group showed significantly superior wound area reduction rate and epithelialization completion time, with also less scar formation.

Key Conclusion

Jaungo is an effective Korean medicine topical preparation that promotes skin wound healing and suppresses scar formation.

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Case Study Skin Conditions

Case Series of Combined Thread-Embedding and Pharmacopuncture Therapy for Keloid

서태영, 한미라, 박세종, et al.

Evidence-Based Complementary and Alternative Medicine (2023)

10 patients Cases
-47.2% Volume reduction rate
10% 6-month recurrence rate

Combined thread-embedding and pharmacopuncture therapy reduces keloid size and hardness and is a non-invasive Korean medicine treatment with low recurrence rate.

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Case Study Skin Conditions

Case Series of Combined Thread-Embedding and Pharmacopuncture Therapy for Keloid

서태영, 한미라, 박세종, et al. Evidence-Based Complementary and Alternative Medicine (2023)
10 patients Cases
-47.2% Volume reduction rate
10% 6-month recurrence rate

Summary

Ten patients with keloid developed after surgery underwent combined thread-embedding therapy and anti-inflammatory pharmacopuncture for 16 weeks. Keloid volume, hardness, and color index significantly decreased, with improvements also observed on Vancouver Scar Scale (VSS). At 6-month follow-up after treatment, only 1 case of recurrence occurred.

Key Conclusion

Combined thread-embedding and pharmacopuncture therapy reduces keloid size and hardness and is a non-invasive Korean medicine treatment with low recurrence rate.

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RCT Skin Conditions

Randomized Controlled Trial of Acupuncture for Facial Flushing: Changes in Heat Sensation and Vascular Reactivity

홍승기, 김연아, 이태준, et al.

Dermatologic Therapy (2023)

48 patients Participants
-61.3% Flushing frequency reduction
p=0.001 Vascular reactivity improvement

Acupuncture reduces the frequency and intensity of facial flushing and improves symptoms through stabilization of skin vascular reactivity.

View Source 2023
RCT Skin Conditions

Randomized Controlled Trial of Acupuncture for Facial Flushing: Changes in Heat Sensation and Vascular Reactivity

홍승기, 김연아, 이태준, et al. Dermatologic Therapy (2023)
48 patients Participants
-61.3% Flushing frequency reduction
p=0.001 Vascular reactivity improvement

Summary

Forty-eight patients with facial flushing were randomly assigned to acupuncture treatment or waitlist groups and compared over 12 weeks. The acupuncture treatment group showed significant decreases in flushing occurrence frequency, duration, and subjective heat sensation scores. Laser Doppler-based vascular reactivity testing confirmed skin blood flow stabilization in the acupuncture group.

Key Conclusion

Acupuncture reduces the frequency and intensity of facial flushing and improves symptoms through stabilization of skin vascular reactivity.

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Cross-Sectional Skin Conditions

Cross-Sectional Analysis of Use Patterns and Effects of Korean Medicine Moisturizing Topical Preparations for Xerosis

유수진, 김건우, 이나래, et al.

Journal of Dermatological Treatment (2023)

312 patients Analysis subjects
87.5% Symptom improvement rate
4.2/5 Mean satisfaction

Korean medicine moisturizing topical preparations are effective for xerosis management, and ceramide-combined formulations enhance patient satisfaction.

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Cross-Sectional Skin Conditions

Cross-Sectional Analysis of Use Patterns and Effects of Korean Medicine Moisturizing Topical Preparations for Xerosis

유수진, 김건우, 이나래, et al. Journal of Dermatological Treatment (2023)
312 patients Analysis subjects
87.5% Symptom improvement rate
4.2/5 Mean satisfaction

Summary

Survey data from 312 patients using Korean medicine moisturizing topical preparations for xerosis were cross-sectionally analyzed. The group using Korean medicine moisturizers (based on Jaungo and Gyeongokgo) for 4 weeks or more showed significant improvements in skin hydration, flexibility, and subjective dryness. Satisfaction was highest with ceramide-containing Korean medicine moisturizers.

Key Conclusion

Korean medicine moisturizing topical preparations are effective for xerosis management, and ceramide-combined formulations enhance patient satisfaction.

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Cohort Study Skin Conditions

Comparative Cohort Study of Jaungo and Transdermal Absorption Enhanced Topical Preparation for Hand Eczema

전미래, 나영진, 박하은, et al.

대한한의학회지 (2024)

67 patients Cohort size
-52.1% HECSI reduction rate
p=0.023 Inter-group difference

Modified Jaungo with added transdermal absorption enhancers improves hand eczema treatment efficacy compared to conventional Jaungo.

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Cohort Study Skin Conditions

Comparative Cohort Study of Jaungo and Transdermal Absorption Enhanced Topical Preparation for Hand Eczema

전미래, 나영진, 박하은, et al. 대한한의학회지 (2024)
67 patients Cohort size
-52.1% HECSI reduction rate
p=0.023 Inter-group difference

Summary

Sixty-seven patients with hand eczema were divided into Jaungo alone and modified Jaungo with added transdermal absorption enhancers and followed for 8 weeks. Both groups showed significant decreases in HECSI scores, but the modified Jaungo group showed faster skin barrier recovery and higher symptom improvement rate.

Key Conclusion

Modified Jaungo with added transdermal absorption enhancers improves hand eczema treatment efficacy compared to conventional Jaungo.

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Before-After Skin Conditions

Effect of Korean Medicine Combination Therapy for Nummular Eczema: A Pre-Post Comparison Study

고지영, 양현석, 김승아, et al.

한방안이비인후피부과학회지 (2023)

38 patients Target patients
-65.4% Eczema area reduction
91.2% Symptom improvement rate

Korean medicine combination therapy simultaneously improves various symptoms of nummular eczema, and combined fumigation treatment is particularly effective for moist lesions.

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Before-After Skin Conditions

Effect of Korean Medicine Combination Therapy for Nummular Eczema: A Pre-Post Comparison Study

고지영, 양현석, 김승아, et al. 한방안이비인후피부과학회지 (2023)
38 patients Target patients
-65.4% Eczema area reduction
91.2% Symptom improvement rate

Summary

Korean medicine combination therapy including herbal medicine (modified Samul-tang), Jaungo application, and fumigation treatment was performed for 6 weeks on 38 patients with nummular eczema. Eczema area, exudate, crust formation, and pruritus all significantly decreased in pre-post comparison. The drying speed of moist lesions was particularly fast in the group combined with fumigation treatment.

Key Conclusion

Korean medicine combination therapy simultaneously improves various symptoms of nummular eczema, and combined fumigation treatment is particularly effective for moist lesions.

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Meta-Analysis Skin Conditions

Meta-Analysis of Pharmacopuncture Treatment for Pruritus

백승현, 조아라, 김태윤, et al.

Journal of Ethnopharmacology (2024)

1,156 patients Total participants
MD -2.7 NRS mean difference
I²=32% Heterogeneity indicator

Pharmacopuncture treatment shows significant efficacy in alleviating pruritus of various etiologies, and component-specific optimization research is needed.

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Meta-Analysis Skin Conditions

Meta-Analysis of Pharmacopuncture Treatment for Pruritus

백승현, 조아라, 김태윤, et al. Journal of Ethnopharmacology (2024)
1,156 patients Total participants
MD -2.7 NRS mean difference
I²=32% Heterogeneity indicator

Summary

The effects of pharmacopuncture treatment for pruritus of various etiologies were meta-analyzed. Analysis of 12 RCTs (total 1,156 patients) showed significant pruritus NRS score reduction and DLQI improvement in the pharmacopuncture group. The highest effect size was observed with Coptis and Sophora flavescens extract-based pharmacopunctures.

Key Conclusion

Pharmacopuncture treatment shows significant efficacy in alleviating pruritus of various etiologies, and component-specific optimization research is needed.

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RCT Skin Conditions

Randomized Controlled Trial of Moxibustion Treatment for Senile Pruritus

차은영, 권혁상, 이지현, et al.

Geriatrics & Gerontology International (2023)

54 patients Participants
-56.8% Pruritus reduction rate
p=0.004 Sleep quality improvement

Moxibustion treatment is a safe and effective non-pharmacological treatment for symptom relief and quality of life improvement in senile pruritus.

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RCT Skin Conditions

Randomized Controlled Trial of Moxibustion Treatment for Senile Pruritus

차은영, 권혁상, 이지현, et al. Geriatrics & Gerontology International (2023)
54 patients Participants
-56.8% Pruritus reduction rate
p=0.004 Sleep quality improvement

Summary

A randomized controlled trial was conducted in 54 elderly patients aged 65 or older with senile pruritus, performing indirect moxibustion at ST36, SP10, LI11, and other acupoints three times weekly for 8 weeks. The moxibustion treatment group showed significant improvements in pruritus scores, sleep disturbance scores, and skin hydration.

Key Conclusion

Moxibustion treatment is a safe and effective non-pharmacological treatment for symptom relief and quality of life improvement in senile pruritus.

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Case Study Skin Conditions

Case Report of Combined Acupuncture and Korean Medicine Topical Preparation for Freckles

배수연, 홍진표, 김지석, et al.

대한침구의학회지 (2024)

8 patients Cases
-32.4% Pigment area reduction
12 weeks Treatment duration

Combined acupuncture and Korean medicine topical preparation therapy is a useful Korean medicine approach for non-invasive improvement of freckles.

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Case Study Skin Conditions

Case Report of Combined Acupuncture and Korean Medicine Topical Preparation for Freckles

배수연, 홍진표, 김지석, et al. 대한침구의학회지 (2024)
8 patients Cases
-32.4% Pigment area reduction
12 weeks Treatment duration

Summary

Cosmetic acupuncture (facial acupoint needling) and pack treatment containing Bombyx mori and Poria were performed twice weekly for 12 weeks on 8 patients with facial freckles. All patients showed reduced pigment lesion size and number, with average 32.4% reduction in pigment area ratio on digital photo analysis.

Key Conclusion

Combined acupuncture and Korean medicine topical preparation therapy is a useful Korean medicine approach for non-invasive improvement of freckles.

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Before-After Skin Conditions

Effect of Korean Medicine Whitening Topical Preparation for Pigmentation Disorders: A Pre-Post Comparison Study

안성호, 김유리, 박재민, et al.

한방안이비인후피부과학회지 (2023)

58 patients Target patients
-38.7% Pigment density reduction
+4.2 L* value improvement

Korean medicine whitening topical preparation is safe and effective for improving post-inflammatory pigmentation and is applicable to sensitive skin.

View Source 2023
Before-After Skin Conditions

Effect of Korean Medicine Whitening Topical Preparation for Pigmentation Disorders: A Pre-Post Comparison Study

안성호, 김유리, 박재민, et al. 한방안이비인후피부과학회지 (2023)
58 patients Target patients
-38.7% Pigment density reduction
+4.2 L* value improvement

Summary

A Korean medicine whitening topical preparation containing Glycyrrhiza, Atractylodes, and Angelica extracts was applied for 8 weeks to 58 patients with post-inflammatory pigmentation. Pigmentation area and density significantly decreased in pre-post comparison, with improved skin brightness (L* value). Irritation reactions were observed at minimal levels.

Key Conclusion

Korean medicine whitening topical preparation is safe and effective for improving post-inflammatory pigmentation and is applicable to sensitive skin.

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Systematic Review Skin Conditions

Systematic Review on Korean Medicine Treatment for Vitiligo

황지은, 나승환, 김보경, et al.

대한한의학회지 (2023)

19 studies Included studies
67.3% Repigmentation rate
OR 2.15 Effect size

Korean medicine treatment promotes repigmentation in vitiligo, and pattern-based personalized treatment maximizes efficacy.

View Source 2023
Systematic Review Skin Conditions

Systematic Review on Korean Medicine Treatment for Vitiligo

황지은, 나승환, 김보경, et al. 대한한의학회지 (2023)
19 studies Included studies
67.3% Repigmentation rate
OR 2.15 Effect size

Summary

Korean medicine interventions used in vitiligo treatment were systematically reviewed. Analysis of 19 studies including herbal medicine (modified Bojungikgi-tang, Yukmijihwang-tang), acupuncture, and topical preparations showed significantly higher repigmentation rates in the Korean medicine treatment group compared to controls. Treatment response rates were particularly excellent in the qi-blood deficiency pattern.

Key Conclusion

Korean medicine treatment promotes repigmentation in vitiligo, and pattern-based personalized treatment maximizes efficacy.

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RCT Neurological Disorders

Randomized Controlled Trial of Bee Venom Pharmacopuncture for Post-Herpetic Neuralgia

조현수, 이다혜, 김영준, et al.

Integrative Medicine Research (2024)

64 patients Participants
-3.4 points NRS reduction
p=0.001 Sleep quality improvement

Bee venom pharmacopuncture is an effective treatment for pain reduction and sleep quality improvement in post-herpetic neuralgia, and can be utilized as complementary or alternative therapy to existing medications.

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RCT Neurological Disorders

Randomized Controlled Trial of Bee Venom Pharmacopuncture for Post-Herpetic Neuralgia

조현수, 이다혜, 김영준, et al. Integrative Medicine Research (2024)
64 patients Participants
-3.4 points NRS reduction
p=0.001 Sleep quality improvement

Summary

A randomized controlled trial comparing bee venom pharmacopuncture treatment versus gabapentin was conducted in 64 patients with post-herpetic neuralgia (PHN). After 8 weeks of treatment, the bee venom pharmacopuncture group showed significantly decreased NRS pain scores and neuropathic pain questionnaire (DN4) scores. Sleep quality improvement was also superior in the bee venom pharmacopuncture group.

Key Conclusion

Bee venom pharmacopuncture is an effective treatment for pain reduction and sleep quality improvement in post-herpetic neuralgia, and can be utilized as complementary or alternative therapy to existing medications.

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