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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Before-After Skin Conditions

Pre-Post Comparison Study of Korean Medicine Combination Therapy for Female Pattern Baldness

윤서희, 김정훈, 이수민, et al.

한방안이비인후피부과학회지 (2024)

52 patients Target patients
+28.6% Hair density increase
83.5% Scalp health improvement rate

Korean medicine combination therapy is effective for hair growth promotion and scalp environment improvement in female pattern baldness, and is particularly useful for hormonal alopecia.

View Source 2024
Before-After Skin Conditions

Pre-Post Comparison Study of Korean Medicine Combination Therapy for Female Pattern Baldness

윤서희, 김정훈, 이수민, et al. 한방안이비인후피부과학회지 (2024)
52 patients Target patients
+28.6% Hair density increase
83.5% Scalp health improvement rate

Summary

Combination therapy including herbal medicine (modified Yukmijihwang-tang), acupuncture, and scalp pharmacopuncture was performed for 16 weeks on 52 patients with female pattern baldness. Hair density, hair diameter, and scalp health scores all significantly improved in pre-post comparison. Improvement was particularly pronounced in postmenopausal women.

Key Conclusion

Korean medicine combination therapy is effective for hair growth promotion and scalp environment improvement in female pattern baldness, and is particularly useful for hormonal alopecia.

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Cross-Sectional Skin Conditions

Cross-Sectional Analysis of Acupuncture Effects for Acute Herpes Zoster Pain

문재환, 박소영, 김대원, et al.

Journal of Pain Research (2023)

200 patients Analysis subjects
-2.8 points Additional VAS reduction
31.4% Analgesic reduction rate

Combined acupuncture in acute herpes zoster results in faster pain control and reduced analgesic use, making it clinically significant.

View Source 2023
Cross-Sectional Skin Conditions

Cross-Sectional Analysis of Acupuncture Effects for Acute Herpes Zoster Pain

문재환, 박소영, 김대원, et al. Journal of Pain Research (2023)
200 patients Analysis subjects
-2.8 points Additional VAS reduction
31.4% Analgesic reduction rate

Summary

Medical records of 200 patients with acute herpes zoster were retrospectively analyzed to compare pain control effects between acupuncture combination and antiviral alone groups. The acupuncture combination group showed significantly faster VAS score reduction and less analgesic use. Progression rate to post-herpetic neuralgia also showed lower trend in the combination group.

Key Conclusion

Combined acupuncture in acute herpes zoster results in faster pain control and reduced analgesic use, making it clinically significant.

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RCT Neurological Disorders

Randomized Controlled Trial of Bee Venom Pharmacopuncture for Post-Herpetic Neuralgia

조현수, 이다혜, 김영준, et al.

Integrative Medicine Research (2024)

64 patients Participants
-3.4 points NRS reduction
p=0.001 Sleep quality improvement

Bee venom pharmacopuncture is an effective treatment for pain reduction and sleep quality improvement in post-herpetic neuralgia, and can be utilized as complementary or alternative therapy to existing medications.

View Source 2024
RCT Neurological Disorders

Randomized Controlled Trial of Bee Venom Pharmacopuncture for Post-Herpetic Neuralgia

조현수, 이다혜, 김영준, et al. Integrative Medicine Research (2024)
64 patients Participants
-3.4 points NRS reduction
p=0.001 Sleep quality improvement

Summary

A randomized controlled trial comparing bee venom pharmacopuncture treatment versus gabapentin was conducted in 64 patients with post-herpetic neuralgia (PHN). After 8 weeks of treatment, the bee venom pharmacopuncture group showed significantly decreased NRS pain scores and neuropathic pain questionnaire (DN4) scores. Sleep quality improvement was also superior in the bee venom pharmacopuncture group.

Key Conclusion

Bee venom pharmacopuncture is an effective treatment for pain reduction and sleep quality improvement in post-herpetic neuralgia, and can be utilized as complementary or alternative therapy to existing medications.

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Systematic Review Skin Conditions

Systematic Review on Korean Medicine Treatment for Vitiligo

황지은, 나승환, 김보경, et al.

대한한의학회지 (2023)

19 studies Included studies
67.3% Repigmentation rate
OR 2.15 Effect size

Korean medicine treatment promotes repigmentation in vitiligo, and pattern-based personalized treatment maximizes efficacy.

View Source 2023
Systematic Review Skin Conditions

Systematic Review on Korean Medicine Treatment for Vitiligo

황지은, 나승환, 김보경, et al. 대한한의학회지 (2023)
19 studies Included studies
67.3% Repigmentation rate
OR 2.15 Effect size

Summary

Korean medicine interventions used in vitiligo treatment were systematically reviewed. Analysis of 19 studies including herbal medicine (modified Bojungikgi-tang, Yukmijihwang-tang), acupuncture, and topical preparations showed significantly higher repigmentation rates in the Korean medicine treatment group compared to controls. Treatment response rates were particularly excellent in the qi-blood deficiency pattern.

Key Conclusion

Korean medicine treatment promotes repigmentation in vitiligo, and pattern-based personalized treatment maximizes efficacy.

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Before-After Skin Conditions

Effect of Korean Medicine Whitening Topical Preparation for Pigmentation Disorders: A Pre-Post Comparison Study

안성호, 김유리, 박재민, et al.

한방안이비인후피부과학회지 (2023)

58 patients Target patients
-38.7% Pigment density reduction
+4.2 L* value improvement

Korean medicine whitening topical preparation is safe and effective for improving post-inflammatory pigmentation and is applicable to sensitive skin.

View Source 2023
Before-After Skin Conditions

Effect of Korean Medicine Whitening Topical Preparation for Pigmentation Disorders: A Pre-Post Comparison Study

안성호, 김유리, 박재민, et al. 한방안이비인후피부과학회지 (2023)
58 patients Target patients
-38.7% Pigment density reduction
+4.2 L* value improvement

Summary

A Korean medicine whitening topical preparation containing Glycyrrhiza, Atractylodes, and Angelica extracts was applied for 8 weeks to 58 patients with post-inflammatory pigmentation. Pigmentation area and density significantly decreased in pre-post comparison, with improved skin brightness (L* value). Irritation reactions were observed at minimal levels.

Key Conclusion

Korean medicine whitening topical preparation is safe and effective for improving post-inflammatory pigmentation and is applicable to sensitive skin.

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Case Study Skin Conditions

Case Report of Combined Acupuncture and Korean Medicine Topical Preparation for Freckles

배수연, 홍진표, 김지석, et al.

대한침구의학회지 (2024)

8 patients Cases
-32.4% Pigment area reduction
12 weeks Treatment duration

Combined acupuncture and Korean medicine topical preparation therapy is a useful Korean medicine approach for non-invasive improvement of freckles.

View Source 2024
Case Study Skin Conditions

Case Report of Combined Acupuncture and Korean Medicine Topical Preparation for Freckles

배수연, 홍진표, 김지석, et al. 대한침구의학회지 (2024)
8 patients Cases
-32.4% Pigment area reduction
12 weeks Treatment duration

Summary

Cosmetic acupuncture (facial acupoint needling) and pack treatment containing Bombyx mori and Poria were performed twice weekly for 12 weeks on 8 patients with facial freckles. All patients showed reduced pigment lesion size and number, with average 32.4% reduction in pigment area ratio on digital photo analysis.

Key Conclusion

Combined acupuncture and Korean medicine topical preparation therapy is a useful Korean medicine approach for non-invasive improvement of freckles.

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RCT Skin Conditions

Randomized Controlled Trial of Moxibustion Treatment for Senile Pruritus

차은영, 권혁상, 이지현, et al.

Geriatrics & Gerontology International (2023)

54 patients Participants
-56.8% Pruritus reduction rate
p=0.004 Sleep quality improvement

Moxibustion treatment is a safe and effective non-pharmacological treatment for symptom relief and quality of life improvement in senile pruritus.

View Source 2023
RCT Skin Conditions

Randomized Controlled Trial of Moxibustion Treatment for Senile Pruritus

차은영, 권혁상, 이지현, et al. Geriatrics & Gerontology International (2023)
54 patients Participants
-56.8% Pruritus reduction rate
p=0.004 Sleep quality improvement

Summary

A randomized controlled trial was conducted in 54 elderly patients aged 65 or older with senile pruritus, performing indirect moxibustion at ST36, SP10, LI11, and other acupoints three times weekly for 8 weeks. The moxibustion treatment group showed significant improvements in pruritus scores, sleep disturbance scores, and skin hydration.

Key Conclusion

Moxibustion treatment is a safe and effective non-pharmacological treatment for symptom relief and quality of life improvement in senile pruritus.

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Meta-Analysis Skin Conditions

Meta-Analysis of Pharmacopuncture Treatment for Pruritus

백승현, 조아라, 김태윤, et al.

Journal of Ethnopharmacology (2024)

1,156 patients Total participants
MD -2.7 NRS mean difference
I²=32% Heterogeneity indicator

Pharmacopuncture treatment shows significant efficacy in alleviating pruritus of various etiologies, and component-specific optimization research is needed.

View Source 2024
Meta-Analysis Skin Conditions

Meta-Analysis of Pharmacopuncture Treatment for Pruritus

백승현, 조아라, 김태윤, et al. Journal of Ethnopharmacology (2024)
1,156 patients Total participants
MD -2.7 NRS mean difference
I²=32% Heterogeneity indicator

Summary

The effects of pharmacopuncture treatment for pruritus of various etiologies were meta-analyzed. Analysis of 12 RCTs (total 1,156 patients) showed significant pruritus NRS score reduction and DLQI improvement in the pharmacopuncture group. The highest effect size was observed with Coptis and Sophora flavescens extract-based pharmacopunctures.

Key Conclusion

Pharmacopuncture treatment shows significant efficacy in alleviating pruritus of various etiologies, and component-specific optimization research is needed.

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Before-After Skin Conditions

Effect of Korean Medicine Combination Therapy for Nummular Eczema: A Pre-Post Comparison Study

고지영, 양현석, 김승아, et al.

한방안이비인후피부과학회지 (2023)

38 patients Target patients
-65.4% Eczema area reduction
91.2% Symptom improvement rate

Korean medicine combination therapy simultaneously improves various symptoms of nummular eczema, and combined fumigation treatment is particularly effective for moist lesions.

View Source 2023
Before-After Skin Conditions

Effect of Korean Medicine Combination Therapy for Nummular Eczema: A Pre-Post Comparison Study

고지영, 양현석, 김승아, et al. 한방안이비인후피부과학회지 (2023)
38 patients Target patients
-65.4% Eczema area reduction
91.2% Symptom improvement rate

Summary

Korean medicine combination therapy including herbal medicine (modified Samul-tang), Jaungo application, and fumigation treatment was performed for 6 weeks on 38 patients with nummular eczema. Eczema area, exudate, crust formation, and pruritus all significantly decreased in pre-post comparison. The drying speed of moist lesions was particularly fast in the group combined with fumigation treatment.

Key Conclusion

Korean medicine combination therapy simultaneously improves various symptoms of nummular eczema, and combined fumigation treatment is particularly effective for moist lesions.

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Cohort Study Skin Conditions

Comparative Cohort Study of Jaungo and Transdermal Absorption Enhanced Topical Preparation for Hand Eczema

전미래, 나영진, 박하은, et al.

대한한의학회지 (2024)

67 patients Cohort size
-52.1% HECSI reduction rate
p=0.023 Inter-group difference

Modified Jaungo with added transdermal absorption enhancers improves hand eczema treatment efficacy compared to conventional Jaungo.

View Source 2024
Cohort Study Skin Conditions

Comparative Cohort Study of Jaungo and Transdermal Absorption Enhanced Topical Preparation for Hand Eczema

전미래, 나영진, 박하은, et al. 대한한의학회지 (2024)
67 patients Cohort size
-52.1% HECSI reduction rate
p=0.023 Inter-group difference

Summary

Sixty-seven patients with hand eczema were divided into Jaungo alone and modified Jaungo with added transdermal absorption enhancers and followed for 8 weeks. Both groups showed significant decreases in HECSI scores, but the modified Jaungo group showed faster skin barrier recovery and higher symptom improvement rate.

Key Conclusion

Modified Jaungo with added transdermal absorption enhancers improves hand eczema treatment efficacy compared to conventional Jaungo.

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Cross-Sectional Skin Conditions

Cross-Sectional Analysis of Use Patterns and Effects of Korean Medicine Moisturizing Topical Preparations for Xerosis

유수진, 김건우, 이나래, et al.

Journal of Dermatological Treatment (2023)

312 patients Analysis subjects
87.5% Symptom improvement rate
4.2/5 Mean satisfaction

Korean medicine moisturizing topical preparations are effective for xerosis management, and ceramide-combined formulations enhance patient satisfaction.

View Source 2023
Cross-Sectional Skin Conditions

Cross-Sectional Analysis of Use Patterns and Effects of Korean Medicine Moisturizing Topical Preparations for Xerosis

유수진, 김건우, 이나래, et al. Journal of Dermatological Treatment (2023)
312 patients Analysis subjects
87.5% Symptom improvement rate
4.2/5 Mean satisfaction

Summary

Survey data from 312 patients using Korean medicine moisturizing topical preparations for xerosis were cross-sectionally analyzed. The group using Korean medicine moisturizers (based on Jaungo and Gyeongokgo) for 4 weeks or more showed significant improvements in skin hydration, flexibility, and subjective dryness. Satisfaction was highest with ceramide-containing Korean medicine moisturizers.

Key Conclusion

Korean medicine moisturizing topical preparations are effective for xerosis management, and ceramide-combined formulations enhance patient satisfaction.

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RCT Skin Conditions

Randomized Controlled Trial of Acupuncture for Facial Flushing: Changes in Heat Sensation and Vascular Reactivity

홍승기, 김연아, 이태준, et al.

Dermatologic Therapy (2023)

48 patients Participants
-61.3% Flushing frequency reduction
p=0.001 Vascular reactivity improvement

Acupuncture reduces the frequency and intensity of facial flushing and improves symptoms through stabilization of skin vascular reactivity.

View Source 2023
RCT Skin Conditions

Randomized Controlled Trial of Acupuncture for Facial Flushing: Changes in Heat Sensation and Vascular Reactivity

홍승기, 김연아, 이태준, et al. Dermatologic Therapy (2023)
48 patients Participants
-61.3% Flushing frequency reduction
p=0.001 Vascular reactivity improvement

Summary

Forty-eight patients with facial flushing were randomly assigned to acupuncture treatment or waitlist groups and compared over 12 weeks. The acupuncture treatment group showed significant decreases in flushing occurrence frequency, duration, and subjective heat sensation scores. Laser Doppler-based vascular reactivity testing confirmed skin blood flow stabilization in the acupuncture group.

Key Conclusion

Acupuncture reduces the frequency and intensity of facial flushing and improves symptoms through stabilization of skin vascular reactivity.

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