금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
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Total 1642 papers

Meta-Analysis Neurological Disorders

Preventive Effect of Acupuncture Treatment in Migraine Patients: A Meta-Analysis

Lim SH, Chang GT, Yamada K, et al.

Headache (2023)

16 studies Included Studies
2,340 subjects Total Participants
-2.8 days Monthly Migraine Reduction

Acupuncture treatment is effective for preventive treatment of migraine and can be considered as an alternative to pharmacological prophylaxis.

Meta-Analysis Neurological Disorders

Preventive Effect of Acupuncture Treatment in Migraine Patients: A Meta-Analysis

Lim SH, Chang GT, Yamada K, et al. Headache (2023)
16 studies Included Studies
2,340 subjects Total Participants
-2.8 days Monthly Migraine Reduction

Summary

A meta-analysis of 16 RCTs (total 2,340 subjects) evaluating the effect of acupuncture treatment for migraine prevention. Acupuncture treatment significantly reduced monthly migraine days.

Key Conclusion

Acupuncture treatment is effective for preventive treatment of migraine and can be considered as an alternative to pharmacological prophylaxis.

Cohort Study Neurological Disorders

Long-Term Effect of Combined Herbal Medicine-Acupuncture Treatment for Sensorineural Tinnitus: A 2-Year Cohort

Oh SH, Jeon MK, Lee BY, et al.

International Tinnitus Journal (2024)

180 subjects Participants
2 years Follow-up Period
43% THI Improvement Rate

Combined herbal medicine-acupuncture treatment is an effective treatment strategy for long-term management of sensorineural tinnitus.

Cohort Study Neurological Disorders

Long-Term Effect of Combined Herbal Medicine-Acupuncture Treatment for Sensorineural Tinnitus: A 2-Year Cohort

Oh SH, Jeon MK, Lee BY, et al. International Tinnitus Journal (2024)
180 subjects Participants
2 years Follow-up Period
43% THI Improvement Rate

Summary

One hundred eighty patients with sensorineural tinnitus were divided into combined herbal medicine-acupuncture treatment and standard treatment groups and followed for 2 years. THI score improvement was greater and more sustained in the combined treatment group.

Key Conclusion

Combined herbal medicine-acupuncture treatment is an effective treatment strategy for long-term management of sensorineural tinnitus.

RCT Neurological Disorders

Effect of Moxibustion Treatment for Cold Hypersensitivity: A Randomized Controlled Trial

Kang HW, Lee JA, et al.

Evidence-Based Complementary and Alternative Medicine (2022)

100 subjects Participants
3.4 points VAS Reduction
6 weeks Treatment Period

Moxibustion treatment improves both subjective cold sensation and objective blood flow indicators in cold hypersensitivity patients.

RCT Neurological Disorders

Effect of Moxibustion Treatment for Cold Hypersensitivity: A Randomized Controlled Trial

Kang HW, Lee JA, et al. Evidence-Based Complementary and Alternative Medicine (2022)
100 subjects Participants
3.4 points VAS Reduction
6 weeks Treatment Period

Summary

One hundred patients with cold hypersensitivity of hands and feet were randomly assigned to moxibustion treatment and sham moxibustion groups and compared for 6 weeks. The moxibustion treatment group showed significant improvements in cold sensation VAS and peripheral vascular resistance index.

Key Conclusion

Moxibustion treatment improves both subjective cold sensation and objective blood flow indicators in cold hypersensitivity patients.

Case Study Neurological Disorders

Effect of Thread Embedding Therapy for Facial Palsy Sequelae: A Case Series

Han GJ, Park WR, et al.

Journal of Acupuncture and Meridian Studies (2021)

12 cases Number of Cases
75% Improvement Rate
3 months Follow-up Period

Thread embedding therapy can contribute to facial function and symmetry improvement in patients with chronic facial palsy sequelae.

Case Study Neurological Disorders

Effect of Thread Embedding Therapy for Facial Palsy Sequelae: A Case Series

Han GJ, Park WR, et al. Journal of Acupuncture and Meridian Studies (2021)
12 cases Number of Cases
75% Improvement Rate
3 months Follow-up Period

Summary

A case report of thread embedding therapy in 12 patients with persistent sequelae after facial palsy for more than 6 months. After the procedure, Sunnybrook scores and facial symmetry indices improved.

Key Conclusion

Thread embedding therapy can contribute to facial function and symmetry improvement in patients with chronic facial palsy sequelae.

Systematic Review Neurological Disorders

Systematic Review of Korean Medicine Treatment for Diabetic Peripheral Neuropathy

Shin DK, Kim AR, Chen L, et al.

Journal of Diabetes Research (2023)

25 studies Included Studies
18 studies Positive Results
Moderate Evidence Level

Korean medicine treatment can be utilized as an adjunctive treatment for symptom relief and nerve function improvement in diabetic peripheral neuropathy.

Systematic Review Neurological Disorders

Systematic Review of Korean Medicine Treatment for Diabetic Peripheral Neuropathy

Shin DK, Kim AR, Chen L, et al. Journal of Diabetes Research (2023)
25 studies Included Studies
18 studies Positive Results
Moderate Evidence Level

Summary

Twenty-five studies on Korean medicine treatment (acupuncture, herbal medicine, pharmacopuncture) for diabetic peripheral neuropathy were systematically reviewed. Nerve conduction velocity (NCV) and symptom scores improved in most studies.

Key Conclusion

Korean medicine treatment can be utilized as an adjunctive treatment for symptom relief and nerve function improvement in diabetic peripheral neuropathy.

Cohort Study Neurological Disorders

Effect of Banhabaekchulcheonma-tang on Dizziness: A Prospective Cohort Study

Yoo JH, Nam ES, et al.

BMC Complementary Medicine and Therapies (2024)

120 subjects Participants
55% Attack Frequency Reduction
6 months Follow-up Period

Banhabaekchulcheonma-tang can significantly reduce symptom frequency and severity of chronic dizziness.

Cohort Study Neurological Disorders

Effect of Banhabaekchulcheonma-tang on Dizziness: A Prospective Cohort Study

Yoo JH, Nam ES, et al. BMC Complementary Medicine and Therapies (2024)
120 subjects Participants
55% Attack Frequency Reduction
6 months Follow-up Period

Summary

A cohort study following 120 chronic dizziness patients for 6 months, divided into Banhabaekchulcheonma-tang administration and non-administration groups. The herbal medicine administration group showed significant decreases in DHI scores and dizziness attack frequency.

Key Conclusion

Banhabaekchulcheonma-tang can significantly reduce symptom frequency and severity of chronic dizziness.

RCT Neurological Disorders

Comparison of Effects of Acupuncture Treatment and Regular Analgesics for Tension Headache: An RCT

Choi JY, Baek HJ, Lee MK, et al.

Cephalalgia (2023)

150 subjects Participants
62% Headache Days Reduction
8 weeks Treatment Period

Acupuncture treatment is more effective than analgesics for chronic tension headache management with fewer side effects.

RCT Neurological Disorders

Comparison of Effects of Acupuncture Treatment and Regular Analgesics for Tension Headache: An RCT

Choi JY, Baek HJ, Lee MK, et al. Cephalalgia (2023)
150 subjects Participants
62% Headache Days Reduction
8 weeks Treatment Period

Summary

One hundred fifty patients with chronic tension headache were randomly assigned to acupuncture treatment and acetaminophen groups and compared for 8 weeks. The acupuncture treatment group was significantly superior in headache days and VAS scores.

Key Conclusion

Acupuncture treatment is more effective than analgesics for chronic tension headache management with fewer side effects.

Meta-Analysis Neurological Disorders

Effect of Acupuncture Treatment for Tinnitus: A Systematic Review and Meta-Analysis

Kim SW, Jung DH, Wang Y, et al.

Otology & Neurotology (2022)

22 studies Included Studies
1,856 subjects Total Participants
SMD -0.72 Effect Size

Acupuncture treatment shows significant effects on symptom severity reduction and quality of life improvement in tinnitus patients.

Meta-Analysis Neurological Disorders

Effect of Acupuncture Treatment for Tinnitus: A Systematic Review and Meta-Analysis

Kim SW, Jung DH, Wang Y, et al. Otology & Neurotology (2022)
22 studies Included Studies
1,856 subjects Total Participants
SMD -0.72 Effect Size

Summary

A meta-analysis of 22 RCTs (total 1,856 subjects) evaluating the effect of acupuncture treatment in tinnitus patients. The acupuncture treatment group showed significant improvement in THI and VAS scores compared with the control group.

Key Conclusion

Acupuncture treatment shows significant effects on symptom severity reduction and quality of life improvement in tinnitus patients.

RCT Neurological Disorders

Peripheral Blood Flow Improvement Effect of Danggwisayeokgaosuyusaenggang-tang in Women with Cold Hypersensitivity

Lee EJ, Song YK, Ito S, et al.

Journal of Ethnopharmacology (2023)

80 subjects Participants
2.3°C Finger Temperature Rise
p<0.001 Statistical Significance

Danggwisayeokgaosuyusaenggang-tang objectively improves peripheral blood flow in cold hypersensitivity patients.

RCT Neurological Disorders

Peripheral Blood Flow Improvement Effect of Danggwisayeokgaosuyusaenggang-tang in Women with Cold Hypersensitivity

Lee EJ, Song YK, Ito S, et al. Journal of Ethnopharmacology (2023)
80 subjects Participants
2.3°C Finger Temperature Rise
p<0.001 Statistical Significance

Summary

Danggwisayeokgaosuyusaenggang-tang was administered for 8 weeks to 80 women complaining of cold hypersensitivity of hands and feet, and peripheral blood flow was evaluated by infrared thermography and laser Doppler. The treatment group showed significant increases in finger skin temperature and blood flow.

Key Conclusion

Danggwisayeokgaosuyusaenggang-tang objectively improves peripheral blood flow in cold hypersensitivity patients.

RCT Neurological Disorders

Effect of Combined Acupuncture and Herbal Medicine Treatment for Acute Facial Palsy: A Multicenter Randomized Controlled Trial

Park SY, Kim HJ, Choi MS, et al.

Neurology (2024)

240 subjects Participants
89% Complete Recovery Rate
5 institutions Multicenter Participation

Combined acupuncture-herbal medicine treatment significantly improved recovery rate and recovery speed in acute facial palsy patients.

RCT Neurological Disorders

Effect of Combined Acupuncture and Herbal Medicine Treatment for Acute Facial Palsy: A Multicenter Randomized Controlled Trial

Park SY, Kim HJ, Choi MS, et al. Neurology (2024)
240 subjects Participants
89% Complete Recovery Rate
5 institutions Multicenter Participation

Summary

Two hundred forty patients with acute Bell's palsy were recruited from 5 Korean medicine hospitals, and combined acupuncture-herbal medicine treatment was compared with steroid alone. After 12 weeks, House-Brackmann grade complete recovery rate was significantly higher in the combined treatment group.

Key Conclusion

Combined acupuncture-herbal medicine treatment significantly improved recovery rate and recovery speed in acute facial palsy patients.

Before-After Men's Health / Urology

Doppler Ultrasound Evaluation of Acupuncture Treatment Effect on Corpus Cavernosum Blood Flow: An Exploratory Study

Han WS, Kim JB, et al.

Journal of Sexual Medicine (2020)

25 subjects Participants
22% PSV Increase Rate
p<0.05 Statistical Significance

Acupuncture treatment can contribute to vasogenic erectile dysfunction treatment by improving corpus cavernosum blood flow.

Before-After Men's Health / Urology

Doppler Ultrasound Evaluation of Acupuncture Treatment Effect on Corpus Cavernosum Blood Flow: An Exploratory Study

Han WS, Kim JB, et al. Journal of Sexual Medicine (2020)
25 subjects Participants
22% PSV Increase Rate
p<0.05 Statistical Significance

Summary

Pre- and post-acupuncture penile Doppler ultrasound was performed in 25 vasogenic erectile dysfunction patients to objectively evaluate cavernosum blood flow changes. PSV and EDV indicators improved significantly.

Key Conclusion

Acupuncture treatment can contribute to vasogenic erectile dysfunction treatment by improving corpus cavernosum blood flow.

Narrative Review Men's Health / Urology

Integrated Review on the Male Hormone Regulation Mechanism of Kidney-Tonifying Herbal Medicine

Cho MH, Lee YR, Zhang L, et al.

Frontiers in Pharmacology (2025)

52 sources Reviewed Literature
4 mechanisms Main Mechanisms
High Evidence Level

Kidney-tonifying herbal medicine regulates male hormone balance through multiple mechanisms, contributing to male health enhancement.

Narrative Review Men's Health / Urology

Integrated Review on the Male Hormone Regulation Mechanism of Kidney-Tonifying Herbal Medicine

Cho MH, Lee YR, Zhang L, et al. Frontiers in Pharmacology (2025)
52 sources Reviewed Literature
4 mechanisms Main Mechanisms
High Evidence Level

Summary

Basic and clinical studies on the male hormone regulation mechanism of kidney-tonifying herbal medicine (deer antler, Epimedium, Cuscuta) were integratively reviewed. Various mechanisms including hypothalamus-pituitary-gonadal axis regulation and antioxidant action were confirmed.

Key Conclusion

Kidney-tonifying herbal medicine regulates male hormone balance through multiple mechanisms, contributing to male health enhancement.