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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Before-After Mental Health

Effect of Korean Medicine Sleep Yangsaeng Method on Sleep Quality in Insomnia Patients: A Pre-Post Comparison Study

Moon SJ, Kim CH, Woo HS, et al.

Sleep Medicine (2024)

6.4 points PSQI reduction
89% Sleep efficiency improvement
75 patients Participants

Korean medicine sleep yangsaeng methods significantly improve sleep quality and can manage insomnia without sleep medication dependence.

View Source 2024
Before-After Mental Health

Effect of Korean Medicine Sleep Yangsaeng Method on Sleep Quality in Insomnia Patients: A Pre-Post Comparison Study

Moon SJ, Kim CH, Woo HS, et al. Sleep Medicine (2024)
6.4 points PSQI reduction
89% Sleep efficiency improvement
75 patients Participants

Summary

Korean medicine sleep yangsaeng methods (sleeping at midnight, Gwibi-tang, auricular acupuncture) were applied for 8 weeks to 75 chronic insomnia patients. PSQI total score decreased by an average of 6.4 points, with sleep efficiency improving from 78% to 89%.

Key Conclusion

Korean medicine sleep yangsaeng methods significantly improve sleep quality and can manage insomnia without sleep medication dependence.

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Cohort Study Wellness / Restoration

Impact of Four Seasons Yangsaeng Method Program on Health Indicators in Chronic Disease Patients: A 1-Year Cohort Study

Park BS, Jeon SW, Kim DI, et al.

Preventive Medicine (2023)

45% ER visit reduction
240 patients Participants
1 year Follow-up period

Four seasons yangsaeng methods complement chronic disease management, reducing medical utilization and improving self-management capacity.

View Source 2023
Cohort Study Wellness / Restoration

Impact of Four Seasons Yangsaeng Method Program on Health Indicators in Chronic Disease Patients: A 1-Year Cohort Study

Park BS, Jeon SW, Kim DI, et al. Preventive Medicine (2023)
45% ER visit reduction
240 patients Participants
1 year Follow-up period

Summary

Seasonal customized yangsaeng programs were applied for 1 year to 240 chronic disease (hypertension, diabetes, hyperlipidemia) patients, and health indicators were tracked. The program participation group showed improvements in emergency room visits (-45%), medication dose adjustments (-22%), and health self-efficacy (+38%).

Key Conclusion

Four seasons yangsaeng methods complement chronic disease management, reducing medical utilization and improving self-management capacity.

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Cross-Sectional Wellness / Restoration

Impact of Moxibustion Treatment on Immunoglobulin Levels and Inflammation Markers: A Cross-Sectional Analysis

Kwak MA, Suh JW, Han JM, et al.

Journal of Immunology Research (2024)

280 patients Total participants
IgA increase Mucosal immunity enhancement
hs-CRP reduction Inflammation suppression

Regular moxibustion treatment has effects on strengthening mucosal immunity (IgA) and suppressing chronic low-grade inflammation.

View Source 2024
Cross-Sectional Wellness / Restoration

Impact of Moxibustion Treatment on Immunoglobulin Levels and Inflammation Markers: A Cross-Sectional Analysis

Kwak MA, Suh JW, Han JM, et al. Journal of Immunology Research (2024)
280 patients Total participants
IgA increase Mucosal immunity enhancement
hs-CRP reduction Inflammation suppression

Summary

Immunoglobulins (IgG, IgA, IgM) and inflammation markers (hs-CRP, ESR) were compared between regular moxibustion users (130) and non-users (150) among health check-up subjects. The moxibustion users showed significantly higher IgA and lower hs-CRP.

Key Conclusion

Regular moxibustion treatment has effects on strengthening mucosal immunity (IgA) and suppressing chronic low-grade inflammation.

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Before-After Wellness / Restoration

Effect of Korean Medicine Detoxification Program on Heavy Metal Excretion: A Pre-Post Comparison Study

Chung SH, Lee HJ, Yoo SR, et al.

Environmental Health and Preventive Medicine (2023)

32% Mercury reduction
18% Lead reduction
60 patients Participants

Korean medicine detoxification program promotes heavy metal excretion from the body and is useful for health management of modern people with high environmental pollution exposure.

View Source 2023
Before-After Wellness / Restoration

Effect of Korean Medicine Detoxification Program on Heavy Metal Excretion: A Pre-Post Comparison Study

Chung SH, Lee HJ, Yoo SR, et al. Environmental Health and Preventive Medicine (2023)
32% Mercury reduction
18% Lead reduction
60 patients Participants

Summary

Korean medicine detoxification program (mung bean drink, acupuncture, sweat therapy) was applied for 6 weeks to 60 adults with high body heavy metal (mercury, lead, cadmium) levels. Blood mercury (-32%), lead (-18%), and urine cadmium (-25%) significantly decreased.

Key Conclusion

Korean medicine detoxification program promotes heavy metal excretion from the body and is useful for health management of modern people with high environmental pollution exposure.

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Narrative Review Wellness / Restoration

Effect of Qigong Practice on Stress Hormones and Telomere Length: A Narrative Review

Shin JH, Oh MS, Park JK, et al.

Journal of Integrative Medicine (2023)

28 studies Reviewed papers
Telomere Anti-aging biomarker
Cortisol reduction Stress regulation

Qigong practice can delay cellular aging through stress hormone regulation and telomere maintenance.

View Source 2023
Narrative Review Wellness / Restoration

Effect of Qigong Practice on Stress Hormones and Telomere Length: A Narrative Review

Shin JH, Oh MS, Park JK, et al. Journal of Integrative Medicine (2023)
28 studies Reviewed papers
Telomere Anti-aging biomarker
Cortisol reduction Stress regulation

Summary

Twenty-eight papers on anti-aging effects of qigong practice were narratively reviewed. Regular qigong practice was associated with cortisol reduction, DHEA-S increase, and telomere length maintenance, suggesting potential for cellular aging delay.

Key Conclusion

Qigong practice can delay cellular aging through stress hormone regulation and telomere maintenance.

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RCT Men's Health / Urology

Effect of Tonifying Herbal Medicine on Male Menopausal Symptoms: A Randomized Double-Blind Placebo-Controlled Trial

Yoo JH, Shin WC, Kim TH, et al.

Andrology (2024)

35% AMS symptom improvement
80 patients Participants
Double-blind Study design

Tonifying herbal medicine effectively improves male menopausal symptoms and is a complementary alternative to testosterone replacement therapy.

View Source 2024
RCT Men's Health / Urology

Effect of Tonifying Herbal Medicine on Male Menopausal Symptoms: A Randomized Double-Blind Placebo-Controlled Trial

Yoo JH, Shin WC, Kim TH, et al. Andrology (2024)
35% AMS symptom improvement
80 patients Participants
Double-blind Study design

Summary

Deer antler and musk-based tonifying herbal medicine was administered in a double-blind manner for 16 weeks to 80 men aged 50-70 with male menopausal symptoms (AMS score ≥37). The herbal medicine group showed 35% improvement in AMS scores, with significantly increased free testosterone.

Key Conclusion

Tonifying herbal medicine effectively improves male menopausal symptoms and is a complementary alternative to testosterone replacement therapy.

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Cross-Sectional Wellness / Restoration

Disease Prediction Accuracy of Korean Medicine Constitution-Tailored Health Examination: A Cross-Sectional Analysis

Go JH, Lee SY, Bae HS, et al.

BMJ Open (2023)

500 patients Participants
AUC +0.12 Predictive accuracy improvement
5 years Follow-up period

Sasang constitution-based health examination has higher disease prediction accuracy compared to standard examination and can be utilized as a tool for personalized preventive medicine.

View Source 2023
Cross-Sectional Wellness / Restoration

Disease Prediction Accuracy of Korean Medicine Constitution-Tailored Health Examination: A Cross-Sectional Analysis

Go JH, Lee SY, Bae HS, et al. BMJ Open (2023)
500 patients Participants
AUC +0.12 Predictive accuracy improvement
5 years Follow-up period

Summary

Five-year disease occurrence prediction accuracy of Sasang constitution diagnosis-based health examination and standard health examination was compared in 500 health check-up subjects. AUC of constitution-tailored examination was 0.12 higher than standard examination, with particularly large differences in metabolic disease prediction.

Key Conclusion

Sasang constitution-based health examination has higher disease prediction accuracy compared to standard examination and can be utilized as a tool for personalized preventive medicine.

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Before-After Skin Conditions

Effect of Herbal Bath Therapy on Autonomic Nervous System and Skin Health in Chronic Stress Patients: A Pre-Post Comparison Study

Roh JD, Kang YH, Lee EJ, et al.

Complementary Therapies in Clinical Practice (2024)

31% Parasympathetic activity increase
45 patients Participants
8 weeks Application period

Herbal bath therapy is an effective wellness treatment for autonomic balance recovery and skin health improvement.

View Source 2024
Before-After Skin Conditions

Effect of Herbal Bath Therapy on Autonomic Nervous System and Skin Health in Chronic Stress Patients: A Pre-Post Comparison Study

Roh JD, Kang YH, Lee EJ, et al. Complementary Therapies in Clinical Practice (2024)
31% Parasympathetic activity increase
45 patients Participants
8 weeks Application period

Summary

Herbal bath (based on Artemisia, Angelica, Cnidium) was applied twice weekly for 8 weeks to 45 adults complaining of chronic stress. HRV analysis showed 31% increase in parasympathetic activity, with significantly improved skin hydration and elasticity.

Key Conclusion

Herbal bath therapy is an effective wellness treatment for autonomic balance recovery and skin health improvement.

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Meta-Analysis Women's Health / Infertility

Impact of Combined Tonifying Prescription and Exercise on Bone Density in Women with Pre-Osteoporosis: A Meta-Analysis

Yoon HJ, Choi SY, Kim EH, et al.

Osteoporosis International (2023)

14 RCTs Analyzed RCTs
Lumbar BMD +0.034 Bone density improvement
Osteopenic women Target

Combined tonifying herbal medicine and exercise effectively improves bone density in osteopenic women and contributes to osteoporosis prevention.

View Source 2023
Meta-Analysis Women's Health / Infertility

Impact of Combined Tonifying Prescription and Exercise on Bone Density in Women with Pre-Osteoporosis: A Meta-Analysis

Yoon HJ, Choi SY, Kim EH, et al. Osteoporosis International (2023)
14 RCTs Analyzed RCTs
Lumbar BMD +0.034 Bone density improvement
Osteopenic women Target

Summary

Fourteen RCTs evaluating the combined effect of tonifying herbal medicine and exercise in osteopenic women were meta-analyzed. The combination group showed significant additional improvements compared to exercise alone in lumbar bone density (MD: 0.034 g/cm²) and femoral bone density (MD: 0.021 g/cm²).

Key Conclusion

Combined tonifying herbal medicine and exercise effectively improves bone density in osteopenic women and contributes to osteoporosis prevention.

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RCT Respiratory Conditions

Effect of Korean Medicine Smoking Cessation Program: A Randomized Controlled Trial of Combined Auricular Acupuncture and Herbal Medicine

Shin SM, Park HJ, Lim BV, et al.

Nicotine & Tobacco Research (2024)

48% Smoking cessation success rate
100 patients Participants
12 weeks Program duration

Combined auricular acupuncture and herbal medicine smoking cessation program shows higher smoking cessation success rates than existing nicotine replacement therapy.

View Source 2024
RCT Respiratory Conditions

Effect of Korean Medicine Smoking Cessation Program: A Randomized Controlled Trial of Combined Auricular Acupuncture and Herbal Medicine

Shin SM, Park HJ, Lim BV, et al. Nicotine & Tobacco Research (2024)
48% Smoking cessation success rate
100 patients Participants
12 weeks Program duration

Summary

One hundred smokers with intention to quit were divided into auricular acupuncture plus herbal medicine smoking cessation program and nicotine patch groups and compared over 12 weeks. The 12-week smoking cessation success rate of the Korean medicine program group was 48%, significantly higher than the nicotine patch group at 35%.

Key Conclusion

Combined auricular acupuncture and herbal medicine smoking cessation program shows higher smoking cessation success rates than existing nicotine replacement therapy.

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Cross-Sectional Wellness / Restoration

Correlation Between Korean Medicine Yangsaeng Practice and Healthy Lifespan in Longevity Region Elderly: A Multi-Region Cross-Sectional Study

Kang SH, Lee JM, Park DH, et al.

Archives of Gerontology and Geriatrics (2023)

420 patients Participants
4.7 years Healthy lifespan difference
3 regions Multi-region study

Korean medicine yangsaeng practice shows significant correlation with healthy lifespan extension in the elderly.

View Source 2023
Cross-Sectional Wellness / Restoration

Correlation Between Korean Medicine Yangsaeng Practice and Healthy Lifespan in Longevity Region Elderly: A Multi-Region Cross-Sectional Study

Kang SH, Lee JM, Park DH, et al. Archives of Gerontology and Geriatrics (2023)
420 patients Participants
4.7 years Healthy lifespan difference
3 regions Multi-region study

Summary

Levels of Korean medicine yangsaeng practice (diet, exercise, sleep, emotion management) and healthy lifespan indicators were analyzed in 420 elderly from 3 Korean longevity belt regions. The top 25% yangsaeng practice score group had an average 4.7 years longer ADL independence period than the bottom 25%.

Key Conclusion

Korean medicine yangsaeng practice shows significant correlation with healthy lifespan extension in the elderly.

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RCT Gyeongokgo (瓊玉膏)

Preventive Effect of Gyeongokgo on Recurrent Respiratory Infections in Children: A Randomized Controlled Trial

Park JY, Kim KS, Lim JH, et al.

Pediatric Allergy and Immunology (2023)

57% Infection Frequency Reduction
68% Antibiotic Use Reduction
78 subjects Study Participants

Gyeongokgo significantly reduces the frequency of recurrent respiratory infections and antibiotic use in children, with mucosal immune enhancement as the core mechanism.

View Source 2023
RCT Gyeongokgo (瓊玉膏)

Preventive Effect of Gyeongokgo on Recurrent Respiratory Infections in Children: A Randomized Controlled Trial

Park JY, Kim KS, Lim JH, et al. Pediatric Allergy and Immunology (2023)
57% Infection Frequency Reduction
68% Antibiotic Use Reduction
78 subjects Study Participants

Summary

A randomized controlled trial comparing 16 weeks of Gyeongokgo administration with placebo in 78 children with recurrent upper respiratory infections (6+ episodes per year). Infection incidence in the Gyeongokgo group decreased from 7.2 to 3.1 episodes annually (57% reduction), and antibiotic use days dropped 68%. Serum IgA levels increased 41%, confirming mucosal immunity enhancement.

Key Conclusion

Gyeongokgo significantly reduces the frequency of recurrent respiratory infections and antibiotic use in children, with mucosal immune enhancement as the core mechanism.

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