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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Case Study Pediatric / Adolescent Care

Case Report of 8 Pediatric Atopic Dermatitis Cases Treated with Heat-Clearing Herbal Medicine

Lim EH, Go SY, et al.

대한한방안이비인후피부과학회지 (2024)

53.2% EASI reduction rate
8 cases Number of cases
Pruritus -61% Pruritus reduction

After combined oral herbal medicine and topical Jaungo treatment, EASI scores decreased by an average of 53.2% and nocturnal pruritus significantly improved, with concurrent improvement in sleep quality.

View Source 2024
Case Study Pediatric / Adolescent Care

Case Report of 8 Pediatric Atopic Dermatitis Cases Treated with Heat-Clearing Herbal Medicine

Lim EH, Go SY, et al. 대한한방안이비인후피부과학회지 (2024)
53.2% EASI reduction rate
8 cases Number of cases
Pruritus -61% Pruritus reduction

Summary

A case report on 8 children with moderate-to-severe atopic dermatitis treated with modified Hwangryeonhaedok-tang and topical Jaungo. EASI scores, pruritus VAS, and sleep quality were followed over 12 weeks.

Key Conclusion

After combined oral herbal medicine and topical Jaungo treatment, EASI scores decreased by an average of 53.2% and nocturnal pruritus significantly improved, with concurrent improvement in sleep quality.

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Cross-Sectional Pediatric / Adolescent Care

Cross-Sectional Analysis of Herbal Medicine and Acupuncture Treatment for Pediatric Myopia Progression Suppression

Cho HM, Lee WJ, et al.

대한한방안이비인후피부과학회지 (2024)

47.2% Myopia progression suppression rate
173 patients Analysis population
-0.38D/year Annual refractive change

Pediatric myopia patients receiving combined herbal medicine and acupuncture treatment showed annual refractive power change of -0.38D, suppressed by 47.2% compared to untreated group (-0.72D), with significantly reduced axial length elongation rate.

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Cross-Sectional Pediatric / Adolescent Care

Cross-Sectional Analysis of Herbal Medicine and Acupuncture Treatment for Pediatric Myopia Progression Suppression

Cho HM, Lee WJ, et al. 대한한방안이비인후피부과학회지 (2024)
47.2% Myopia progression suppression rate
173 patients Analysis population
-0.38D/year Annual refractive change

Summary

A cross-sectional analysis of medical records from 173 children with myopia progression. Refractive power and axial length changes after modified Gigukjihwang-tang and periocular acupuncture (BL2, ST2, EX-HN5) were investigated.

Key Conclusion

Pediatric myopia patients receiving combined herbal medicine and acupuncture treatment showed annual refractive power change of -0.38D, suppressed by 47.2% compared to untreated group (-0.72D), with significantly reduced axial length elongation rate.

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Case Study Pediatric / Adolescent Care

Case Report of 9 Children with Recurrent Upper Respiratory Tract Infections Treated with Herbal Medicine and Moxibustion

Woo SJ, Lee KH, et al.

대한한방소아과학회지 (2024)

62.5% Infection frequency reduction
71.4% Antibiotic use reduction
9 cases Number of cases

After combined herbal medicine and moxibustion treatment, upper respiratory tract infection frequency decreased by an average of 62.5% and antibiotic use also decreased by 71.4%, confirming the efficacy of Korean medicine treatment in managing recurrent upper respiratory tract infections.

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Case Study Pediatric / Adolescent Care

Case Report of 9 Children with Recurrent Upper Respiratory Tract Infections Treated with Herbal Medicine and Moxibustion

Woo SJ, Lee KH, et al. 대한한방소아과학회지 (2024)
62.5% Infection frequency reduction
71.4% Antibiotic use reduction
9 cases Number of cases

Summary

A case report on 9 children with recurrent upper respiratory tract infections (8 or more per year) treated with modified Samso-eum and moxibustion at GV14 and BL12. Infection frequency and antibiotic use changes were followed over 6 months.

Key Conclusion

After combined herbal medicine and moxibustion treatment, upper respiratory tract infection frequency decreased by an average of 62.5% and antibiotic use also decreased by 71.4%, confirming the efficacy of Korean medicine treatment in managing recurrent upper respiratory tract infections.

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Before-After Neurological Disorders

Peripheral Nerve Protective Effect of Herbal Medicine for Diabetic Foot Ulcer: A Pre-Post Comparison

Suh JW, Bae GE, Park YC, et al.

Diabetic Medicine (2024)

15% Conduction velocity↑
25 subjects Participants
Ulcer↓ Healing Promotion

Herbal medicine supports peripheral nerve protection and ulcer healing in diabetic feet.

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Before-After Neurological Disorders

Peripheral Nerve Protective Effect of Herbal Medicine for Diabetic Foot Ulcer: A Pre-Post Comparison

Suh JW, Bae GE, Park YC, et al. Diabetic Medicine (2024)
15% Conduction velocity↑
25 subjects Participants
Ulcer↓ Healing Promotion

Summary

Herbal medicine (Samul-tang + Ucha-Sinki-hwan) was administered for 16 weeks to 25 patients with diabetic foot ulcer, and nerve conduction and ulcer healing were tracked. Sensory nerve conduction improved by 15%, and ulcer area decreased.

Key Conclusion

Herbal medicine supports peripheral nerve protection and ulcer healing in diabetic feet.

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Narrative Review Neurological Disorders

Antiplatelet and Antioxidant Effects of Herbal Medicine for Stroke Prevention: A Narrative Review

Park BS, Kang JH, Lee EH, et al.

Cerebrovascular Diseases (2024)

22 sources Reviewed Literature
Antiplatelet Thrombosis Prevention
Antioxidant Brain Protection

Herbal medicine is promising as adjunctive antiplatelet and antioxidant treatment for secondary stroke prevention.

View Source 2024
Narrative Review Neurological Disorders

Antiplatelet and Antioxidant Effects of Herbal Medicine for Stroke Prevention: A Narrative Review

Park BS, Kang JH, Lee EH, et al. Cerebrovascular Diseases (2024)
22 sources Reviewed Literature
Antiplatelet Thrombosis Prevention
Antioxidant Brain Protection

Summary

Twenty-two articles on the antiplatelet and antioxidant effects of herbal medicine for stroke prevention were reviewed. Danshen, Cnidium, and other herbs showed effects on platelet aggregation inhibition and oxidative stress reduction.

Key Conclusion

Herbal medicine is promising as adjunctive antiplatelet and antioxidant treatment for secondary stroke prevention.

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Case Study Neurological Disorders

Case Report of Herbal Medicine (Cheonmaguodeung-eum) for Parkinson's Disease

Shin JH, Kang YH, Oh MS, et al.

Parkinson Disease (2024)

6 cases Number of Cases
Non-motor↓ Sleep, Constipation, Depression
24 weeks Administration Period

Cheonmaguodeung-eum may be useful as an adjunct for non-motor symptom management in Parkinson's disease.

View Source 2024
Case Study Neurological Disorders

Case Report of Herbal Medicine (Cheonmaguodeung-eum) for Parkinson's Disease

Shin JH, Kang YH, Oh MS, et al. Parkinson Disease (2024)
6 cases Number of Cases
Non-motor↓ Sleep, Constipation, Depression
24 weeks Administration Period

Summary

A case report of Cheonmaguodeung-eum administration for 24 weeks in 6 patients with Parkinson's disease. While maintaining L-dopa dose, UPDRS non-motor symptoms (sleep, constipation, depression) improved.

Key Conclusion

Cheonmaguodeung-eum may be useful as an adjunct for non-motor symptom management in Parkinson's disease.

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Cohort Study Neurological Disorders

Preventive Effect of Herbal Medicine for Chronic Headache: A Cohort Study

Noh HM, Ahn YJ, Cho HJ, et al.

Headache (2024)

55% Headache days↓
100 subjects Participants
Medication overuse↓ Dose Reduction Effect

Cheongung-Dajo-san is effective for long-term preventive treatment of chronic headache.

View Source 2024
Cohort Study Neurological Disorders

Preventive Effect of Herbal Medicine for Chronic Headache: A Cohort Study

Noh HM, Ahn YJ, Cho HJ, et al. Headache (2024)
55% Headache days↓
100 subjects Participants
Medication overuse↓ Dose Reduction Effect

Summary

One hundred patients with chronic headache were followed for 24 weeks, divided into herbal medicine (Cheongung-Dajo-san) and non-administration groups. The herbal medicine group showed 55% reduction in monthly headache days and decreased acute medication overuse.

Key Conclusion

Cheongung-Dajo-san is effective for long-term preventive treatment of chronic headache.

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RCT Neurological Disorders

Randomized Controlled Trial of Combined Herbal Medicine and Acupuncture for Carpal Tunnel Syndrome

Kim TH, Song MY, Park CW, et al.

Muscle & Nerve (2023)

48% BQ↓
65 subjects Participants
Conduction↑ Nerve Improvement

Combined herbal medicine and acupuncture is superior to splinting for carpal tunnel syndrome.

View Source 2023
RCT Neurological Disorders

Randomized Controlled Trial of Combined Herbal Medicine and Acupuncture for Carpal Tunnel Syndrome

Kim TH, Song MY, Park CW, et al. Muscle & Nerve (2023)
48% BQ↓
65 subjects Participants
Conduction↑ Nerve Improvement

Summary

Sixty-five patients with carpal tunnel syndrome were compared between herbal medicine + acupuncture and splint groups for 8 weeks. The Korean medicine treatment group showed significantly greater improvements in BQ symptom scores (-48%) and median nerve conduction.

Key Conclusion

Combined herbal medicine and acupuncture is superior to splinting for carpal tunnel syndrome.

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Before-After Neurological Disorders

Pre-Post Comparison Study of Herbal Medicine (Cheongsim-Yeonja-eum) for Post-Stroke Cognitive Impairment

Kwon CY, Song JH, Lee DH, et al.

Stroke (2024)

MoCA +4.2 Cognition↑
40 subjects Participants
TMT↑ Executive Function

Cheongsim-Yeonja-eum is effective for recovery from post-stroke cognitive impairment.

View Source 2024
Before-After Neurological Disorders

Pre-Post Comparison Study of Herbal Medicine (Cheongsim-Yeonja-eum) for Post-Stroke Cognitive Impairment

Kwon CY, Song JH, Lee DH, et al. Stroke (2024)
MoCA +4.2 Cognition↑
40 subjects Participants
TMT↑ Executive Function

Summary

Cheongsim-Yeonja-eum was administered for 16 weeks to 40 patients with post-stroke cognitive impairment. MoCA (+4.2 points) and Trail Making Test significantly improved.

Key Conclusion

Cheongsim-Yeonja-eum is effective for recovery from post-stroke cognitive impairment.

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Case Study Neurological Disorders

Case Report of Herbal Medicine (Modified Samul-tang) for Paresthesia (Burning Sensation)

Kim GH, Cho WS, Park HJ, et al.

Pain Medicine (2023)

8 cases Number of Cases
70%↓ Burning Sensation Reduction
Sleep↑ Additional Effect

Modified Samul-tang may be effective for Korean medicine management of paresthesia (burning sensation).

View Source 2023
Case Study Neurological Disorders

Case Report of Herbal Medicine (Modified Samul-tang) for Paresthesia (Burning Sensation)

Kim GH, Cho WS, Park HJ, et al. Pain Medicine (2023)
8 cases Number of Cases
70%↓ Burning Sensation Reduction
Sleep↑ Additional Effect

Summary

A case report of modified Samul-tang administration for 12 weeks in 8 patients with unexplained limb burning sensation. Burning sensation decreased by more than 70% in 6 patients, with sleep improvement.

Key Conclusion

Modified Samul-tang may be effective for Korean medicine management of paresthesia (burning sensation).

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Before-After Neurological Disorders

Hippocampal Volume Changes with Herbal Medicine (Jogudeung-san) for Mild Cognitive Impairment: A Pre-Post Comparison

Kang YH, Moon SJ, Cho WS, et al.

Neurobiology of Aging (2024)

Hippocampal protection Atrophy Suppression
35 subjects Participants
MoCA↑ Cognition↑

Jogudeung-san shows neuroprotective effects of suppressing hippocampal atrophy in mild cognitive impairment.

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Before-After Neurological Disorders

Hippocampal Volume Changes with Herbal Medicine (Jogudeung-san) for Mild Cognitive Impairment: A Pre-Post Comparison

Kang YH, Moon SJ, Cho WS, et al. Neurobiology of Aging (2024)
Hippocampal protection Atrophy Suppression
35 subjects Participants
MoCA↑ Cognition↑

Summary

Jogudeung-san was administered for 24 weeks to 35 elderly patients with mild cognitive impairment, and hippocampal volume was compared by MRI. Hippocampal volume reduction was significantly attenuated compared with the control group, and MoCA improved.

Key Conclusion

Jogudeung-san shows neuroprotective effects of suppressing hippocampal atrophy in mild cognitive impairment.

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Cohort Study Neurological Disorders

Differences in Treatment Response by Sasang Constitution-Specific Herbal Medicine for Headache: A Cohort Study

Moon PD, Kang BK, Cho WS, et al.

Journal of Korean Medicine (2023)

180 subjects Participants
28% Additional Improvement
Constitution customization Personalized Treatment

Sasang constitution-specific customized herbal medicine improves treatment response for headache.

View Source 2023
Cohort Study Neurological Disorders

Differences in Treatment Response by Sasang Constitution-Specific Herbal Medicine for Headache: A Cohort Study

Moon PD, Kang BK, Cho WS, et al. Journal of Korean Medicine (2023)
180 subjects Participants
28% Additional Improvement
Constitution customization Personalized Treatment

Summary

One hundred eighty patients with headache were followed for 12 weeks, divided into Sasang constitution-specific customized herbal medicine and standard herbal medicine groups. The customized group showed 28% additional improvement in HIT-6 headache impact scores.

Key Conclusion

Sasang constitution-specific customized herbal medicine improves treatment response for headache.

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