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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Meta-Analysis TMJ Disorder

Effect of acupuncture on temporomandibular disorder pain: a systematic review and meta-analysis

La Touche R, Goddard G, De-la-Hoz JL, et al.

Journal of Alternative and Complementary Medicine (2010)

72% Pain Improvement
4.3mm Mouth Opening Increase
7 Studies Studies Included

Acupuncture-moxibustion shows significant effects on pain relief and functional recovery in TMD patients, and may be considered as a first-line treatment option particularly in the masticatory myofascial pain subtype.

View Source 2010
Meta-Analysis TMJ Disorder

Effect of acupuncture on temporomandibular disorder pain: a systematic review and meta-analysis

La Touche R, Goddard G, De-la-Hoz JL, et al. Journal of Alternative and Complementary Medicine (2010)
72% Pain Improvement
4.3mm Mouth Opening Increase
7 Studies Studies Included

Summary

A meta-analysis of 7 RCTs on acupuncture for TMD patients showed the acupuncture group reduced VAS pain scores by an average 2.2 points (out of 10) more than controls. The largest effect size appeared in the myofascial pain subtype.

Key Conclusion

Acupuncture-moxibustion shows significant effects on pain relief and functional recovery in TMD patients, and may be considered as a first-line treatment option particularly in the masticatory myofascial pain subtype.

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RCT TMJ Disorder

Comparison of pharmacopuncture vs. physical therapy for temporomandibular disorder: a randomized controlled trial

Kim TH, Kang JW, Kim KH, et al.

Journal of Korean Medicine (2021)

41% Pressure Threshold Increase
89% Patient Satisfaction
6 Weeks Treatment Duration

Pharmacopuncture therapy demonstrates superior effects compared to physical therapy in reducing masticatory muscle tenderness and recovering function in chronic TMD patients, and can be utilized as a core component of non-surgical integrated treatment.

View Source 2021
RCT TMJ Disorder

Comparison of pharmacopuncture vs. physical therapy for temporomandibular disorder: a randomized controlled trial

Kim TH, Kang JW, Kim KH, et al. Journal of Korean Medicine (2021)
41% Pressure Threshold Increase
89% Patient Satisfaction
6 Weeks Treatment Duration

Summary

A 6-week RCT in 86 patients with chronic TMD comparing pharmacopuncture vs. physical therapy (TENS + ultrasound). The pharmacopuncture group raised masticatory muscle pain pressure threshold by an average 41% from baseline — significantly more than physical therapy (23%).

Key Conclusion

Pharmacopuncture therapy demonstrates superior effects compared to physical therapy in reducing masticatory muscle tenderness and recovering function in chronic TMD patients, and can be utilized as a core component of non-surgical integrated treatment.

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Narrative Review TMJ Disorder

Effect of combined herbal prescriptions on TMD-related tinnitus and headache: a prospective observational study

Cho SH, Kim JH, Lee YJ, et al.

Journal of Korean Medicine (2023)

46% Mouth Opening Increase
72% Accompanying Symptom Improvement
48 Patients Participants

Integrated Korean medicine treatment significantly improved not only joint function in temporomandibular disorder but also accompanying symptoms such as tinnitus and headache, confirming the validity of an integrated treatment approach.

View Source 2023
Narrative Review TMJ Disorder

Effect of combined herbal prescriptions on TMD-related tinnitus and headache: a prospective observational study

Cho SH, Kim JH, Lee YJ, et al. Journal of Korean Medicine (2023)
46% Mouth Opening Increase
72% Accompanying Symptom Improvement
48 Patients Participants

Summary

An 8-week observational study of 48 patients with TMD accompanied by tinnitus/headache receiving herbal medicine (modified So-shi-ho-tang) with acupuncture and chuna therapy. Mouth opening increased from 28mm to 41mm on average, and accompanying symptoms (tinnitus/headache) improved in 72%.

Key Conclusion

Integrated Korean medicine treatment significantly improved not only joint function in temporomandibular disorder but also accompanying symptoms such as tinnitus and headache, confirming the validity of an integrated treatment approach.

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Case Study Pediatric / Adolescent Care

Case Report of 6 Cases of Combined Chuna Therapy and Herbal Medicine for Pediatric Headache

Gong JH, Im SK, et al.

대한추나의학회지 (2024)

Headache -69.9% Headache frequency reduction
6 cases Number of cases
8 weeks Treatment duration

After combined Chuna therapy and herbal medicine treatment, headache frequency decreased from an average of 12.3 to 3.7 times per month, and cervical range of motion also significantly improved, confirming the efficacy of cervical Chuna for pediatric headache.

View Source 2024
Case Study Pediatric / Adolescent Care

Case Report of 6 Cases of Combined Chuna Therapy and Herbal Medicine for Pediatric Headache

Gong JH, Im SK, et al. 대한추나의학회지 (2024)
Headache -69.9% Headache frequency reduction
6 cases Number of cases
8 weeks Treatment duration

Summary

A case report on 6 children with chronic headache (tension-type) treated with combined cervical Chuna therapy and modified Cheonung-dajosan. Headache frequency, VAS, and headache diary were analyzed over 8 weeks.

Key Conclusion

After combined Chuna therapy and herbal medicine treatment, headache frequency decreased from an average of 12.3 to 3.7 times per month, and cervical range of motion also significantly improved, confirming the efficacy of cervical Chuna for pediatric headache.

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Before-After Pediatric / Adolescent Care

Pre-Post Comparison Study of Immune Indicator Changes After Herbal Medicine Treatment in Children with Recurrent Upper Respiratory Tract Infections

Jang HY, Kim WS, et al.

대한한방내과학회지 (2023)

NK +26.3% NK cell activity elevation
CD4/CD8 normalized T-cell ratio improvement
67 patients Study population

After modified Bojungikgi-tang treatment, CD4+/CD8+ ratio normalized and NK cell activity and IFN-g levels significantly increased, confirming cellular immune-enhancing effects.

View Source 2023
Before-After Pediatric / Adolescent Care

Pre-Post Comparison Study of Immune Indicator Changes After Herbal Medicine Treatment in Children with Recurrent Upper Respiratory Tract Infections

Jang HY, Kim WS, et al. 대한한방내과학회지 (2023)
NK +26.3% NK cell activity elevation
CD4/CD8 normalized T-cell ratio improvement
67 patients Study population

Summary

A pre-post comparison over 12 weeks of T-cell subsets (CD4+, CD8+), NK cells, and cytokines (IL-2, IFN-g) before and after modified Bojungikgi-tang administration in 67 children with recurrent upper respiratory tract infections.

Key Conclusion

After modified Bojungikgi-tang treatment, CD4+/CD8+ ratio normalized and NK cell activity and IFN-g levels significantly increased, confirming cellular immune-enhancing effects.

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Cross-Sectional Pediatric / Adolescent Care

Cross-Sectional Analysis of Gut Microbiota Changes After Herbal Medicine Treatment in Children with Anorexia

Jeong DK, Ryu SJ, et al.

대한한방소아과학회지 (2024)

Shannon +0.42 Microbial diversity increase
94 patients Analysis population
Beneficial bacteria +34.5% Beneficial bacteria ratio increase

After herbal medicine treatment, gut microbiota diversity index (Shannon index) significantly increased, and Lactobacillus and Bifidobacterium ratios rose, confirming intestinal environment improvement effects of herbal medicine.

View Source 2024
Cross-Sectional Pediatric / Adolescent Care

Cross-Sectional Analysis of Gut Microbiota Changes After Herbal Medicine Treatment in Children with Anorexia

Jeong DK, Ryu SJ, et al. 대한한방소아과학회지 (2024)
Shannon +0.42 Microbial diversity increase
94 patients Analysis population
Beneficial bacteria +34.5% Beneficial bacteria ratio increase

Summary

A cross-sectional analysis of gut microbiota community (16S rRNA sequencing) changes before and after modified Hyangsayangwi-tang treatment in 94 pediatric patients with anorexia. Microbial diversity index and beneficial bacteria ratios were investigated.

Key Conclusion

After herbal medicine treatment, gut microbiota diversity index (Shannon index) significantly increased, and Lactobacillus and Bifidobacterium ratios rose, confirming intestinal environment improvement effects of herbal medicine.

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Cohort Study Pediatric / Adolescent Care

Cohort Study of Sasang Constitution-Tailored Herbal Medicine Treatment for Pediatric Indigestion

Moon SR, Choi HJ, et al.

대한한방소아과학회지 (2023)

89.8% Overall efficacy rate
167 patients Study population
Soeumin 94.2% Soeumin efficacy rate

Sasang constitution-tailored herbal medicine treatment improved overall efficacy rate to 89.8% in pediatric dyspepsia, with the best results for Insam-yangwi-tang in the Soeumin type.

View Source 2023
Cohort Study Pediatric / Adolescent Care

Cohort Study of Sasang Constitution-Tailored Herbal Medicine Treatment for Pediatric Indigestion

Moon SR, Choi HJ, et al. 대한한방소아과학회지 (2023)
89.8% Overall efficacy rate
167 patients Study population
Soeumin 94.2% Soeumin efficacy rate

Summary

A cohort study following 167 children with functional dyspepsia classified by Sasang constitution for 6 months for constitution-tailored herbal medicine treatment efficacy. Treatment response rates were compared by Soeumin, Soyangin, and Taeumin types.

Key Conclusion

Sasang constitution-tailored herbal medicine treatment improved overall efficacy rate to 89.8% in pediatric dyspepsia, with the best results for Insam-yangwi-tang in the Soeumin type.

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RCT Pediatric / Adolescent Care

Randomized Controlled Trial of Combined Herbal Medicine and Moxibustion for Children with Frequent Colds

Lee CW, Kim HS, et al.

대한한방내과학회지 (2024)

Additional -1.4 episodes Additional cold frequency reduction
88 patients Study population
6 months Follow-up period

The combined herbal medicine and moxibustion group showed an additional 1.4 episodes reduction in cold frequency compared to the herbal medicine alone group, with significantly higher salivary IgA levels, confirming additional immune-enhancing effects of moxibustion.

View Source 2024
RCT Pediatric / Adolescent Care

Randomized Controlled Trial of Combined Herbal Medicine and Moxibustion for Children with Frequent Colds

Lee CW, Kim HS, et al. 대한한방내과학회지 (2024)
Additional -1.4 episodes Additional cold frequency reduction
88 patients Study population
6 months Follow-up period

Summary

An RCT comparing a modified Samso-eum and ST36 moxibustion combination group with an herbal medicine alone group in 88 children with 7 or more colds per year. Cold frequency and immune indicators were followed over 6 months.

Key Conclusion

The combined herbal medicine and moxibustion group showed an additional 1.4 episodes reduction in cold frequency compared to the herbal medicine alone group, with significantly higher salivary IgA levels, confirming additional immune-enhancing effects of moxibustion.

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Systematic Review Pediatric / Adolescent Care

Systematic Review of Herbal Medicine Treatment for Boys with Precocious Puberty

Shin YR, Ahn KS, et al.

대한한방소아과학회지 (2024)

Bone age slowing 0.6 years Bone age progression suppression
7 studies Included studies
p<0.01 Statistical significance

Herbal medicine treatment significantly slowed bone age progression in boys with precocious puberty and also showed effects on testosterone level stabilization, presenting potential as adjunctive treatment to GnRH agonists.

View Source 2024
Systematic Review Pediatric / Adolescent Care

Systematic Review of Herbal Medicine Treatment for Boys with Precocious Puberty

Shin YR, Ahn KS, et al. 대한한방소아과학회지 (2024)
Bone age slowing 0.6 years Bone age progression suppression
7 studies Included studies
p<0.01 Statistical significance

Summary

A systematic review of herbal medicine (modified Jibaekjihwang-tang, Daebo-eumhwan) treatment efficacy in boys with precocious puberty. Seven studies were analyzed for bone age progression rate, testicular volume, and testosterone levels.

Key Conclusion

Herbal medicine treatment significantly slowed bone age progression in boys with precocious puberty and also showed effects on testosterone level stabilization, presenting potential as adjunctive treatment to GnRH agonists.

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Case Study Pediatric / Adolescent Care

Case Report of 5 Cases of Long-Term Herbal Medicine Treatment for Tourette Syndrome in Children and Adolescents

Bae GH, Yoon CH, et al.

대한한방신경정신과학회지 (2024)

52.8% YGTSS reduction rate
4/5 cases CGI improvement
24 weeks Treatment duration

After 24 weeks of combined herbal medicine and acupuncture treatment, total YGTSS scores decreased by an average of 52.8%, and 4 of 5 cases were assessed as much improved or better on CGI, confirming efficacy of long-term treatment.

View Source 2024
Case Study Pediatric / Adolescent Care

Case Report of 5 Cases of Long-Term Herbal Medicine Treatment for Tourette Syndrome in Children and Adolescents

Bae GH, Yoon CH, et al. 대한한방신경정신과학회지 (2024)
52.8% YGTSS reduction rate
4/5 cases CGI improvement
24 weeks Treatment duration

Summary

A long-term follow-up case report on 5 children and adolescents with Tourette syndrome treated with modified Cheonmagudeung-eum and acupuncture (GV20, GB20, LR3) for 24 weeks. YGTSS, CGI, and quality of life were evaluated.

Key Conclusion

After 24 weeks of combined herbal medicine and acupuncture treatment, total YGTSS scores decreased by an average of 52.8%, and 4 of 5 cases were assessed as much improved or better on CGI, confirming efficacy of long-term treatment.

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Cohort Study Pediatric / Adolescent Care

Cohort Study on Effect of Herbal Medicine Treatment for ADHD Children on Academic Concentration

Sung JW, Chae BK, et al.

대한한방신경정신과학회지 (2023)

29.6% CPT error rate reduction
142 patients Study population
6 months Follow-up period

The modified Gwibieondam-tang treatment group showed a 29.6% reduction in CPT error rate and significantly improved response time variability, proving effective for improving academic concentration in children with ADHD.

View Source 2023
Cohort Study Pediatric / Adolescent Care

Cohort Study on Effect of Herbal Medicine Treatment for ADHD Children on Academic Concentration

Sung JW, Chae BK, et al. 대한한방신경정신과학회지 (2023)
29.6% CPT error rate reduction
142 patients Study population
6 months Follow-up period

Summary

A cohort study following 142 children with ADHD for 6 months, comparing a modified Gwibieondam-tang treatment group with a non-treatment group. CPT (Continuous Performance Test), school grades, and teacher behavior assessment were compared.

Key Conclusion

The modified Gwibieondam-tang treatment group showed a 29.6% reduction in CPT error rate and significantly improved response time variability, proving effective for improving academic concentration in children with ADHD.

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Systematic Review Pediatric / Adolescent Care

Systematic Review of Winter Herbal Medicine Treatment for Preventing Pediatric Asthma

Yoo KM, Choi JR, et al.

대한한방내과학회지 (2024)

43.8% Acute exacerbation reduction
10 studies Included studies
Hospitalization -37% Hospitalization rate reduction

Winter herbal medicine preventive treatment reduced acute exacerbation of pediatric asthma in winter by 43.8% and significantly lowered emergency room visit and hospitalization rates, presenting evidence for preventive Korean medicine treatment.

View Source 2024
Systematic Review Pediatric / Adolescent Care

Systematic Review of Winter Herbal Medicine Treatment for Preventing Pediatric Asthma

Yoo KM, Choi JR, et al. 대한한방내과학회지 (2024)
43.8% Acute exacerbation reduction
10 studies Included studies
Hospitalization -37% Hospitalization rate reduction

Summary

A systematic review of herbal medicine (Bopyejungcheon-tang, modified Yukgunja-tang) treatment efficacy for preventing winter exacerbation of pediatric asthma. Ten studies were analyzed for winter asthma attack frequency and hospitalization rates.

Key Conclusion

Winter herbal medicine preventive treatment reduced acute exacerbation of pediatric asthma in winter by 43.8% and significantly lowered emergency room visit and hospitalization rates, presenting evidence for preventive Korean medicine treatment.

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