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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
RCT ENT Disorders

Immunomodulatory Effect of Moxibustion at Yingxiang for Allergic Rhinitis: A Randomized Controlled Trial

Son JY, Lee AR, Moon PD, et al.

Immunology Letters (2023)

28% IgE Reduction Rate
54% Symptom Reduction Rate
104 subjects Participants

Moxibustion at Yingxiang simultaneously improves immunological markers and clinical symptoms in allergic rhinitis.

View Source 2023
RCT ENT Disorders

Immunomodulatory Effect of Moxibustion at Yingxiang for Allergic Rhinitis: A Randomized Controlled Trial

Son JY, Lee AR, Moon PD, et al. Immunology Letters (2023)
28% IgE Reduction Rate
54% Symptom Reduction Rate
104 subjects Participants

Summary

One hundred four patients with allergic rhinitis were assigned to moxibustion at Yingxiang (LI20) or sham moxibustion control groups for 6 weeks of treatment. The moxibustion group demonstrated an average 28% reduction in serum IgE and improvement in IL-4/IFN-γ ratio toward normalization, with sneezing and rhinorrhea symptoms decreasing by 54%.

Key Conclusion

Moxibustion at Yingxiang simultaneously improves immunological markers and clinical symptoms in allergic rhinitis.

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Before-After ENT Disorders

Olfactory Recovery Effect of Tonggyu-tang for Olfactory Dysfunction After Chronic Sinusitis: A Pre-Post Comparison Study

Cho YS, Jung DH, Byun JY, et al.

Chemical Senses (2024)

7.8 points TDI Score Improvement
42% Olfactory Normalization
47 subjects Participants

Tonggyu-tang is an effective herbal treatment that promotes recovery from olfactory dysfunction after chronic sinusitis surgery.

View Source 2024
Before-After ENT Disorders

Olfactory Recovery Effect of Tonggyu-tang for Olfactory Dysfunction After Chronic Sinusitis: A Pre-Post Comparison Study

Cho YS, Jung DH, Byun JY, et al. Chemical Senses (2024)
7.8 points TDI Score Improvement
42% Olfactory Normalization
47 subjects Participants

Summary

Forty-seven patients with persistent olfactory dysfunction after chronic sinusitis surgery received Tonggyu-tang for 12 weeks, with pre- and post-treatment KVSS II olfactory testing compared. TDI scores improved by an average of 7.8 points, with 42% reaching normosmia criteria (TDI≥30.5).

Key Conclusion

Tonggyu-tang is an effective herbal treatment that promotes recovery from olfactory dysfunction after chronic sinusitis surgery.

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Cross-Sectional ENT Disorders

Effect of Thread Embedding Therapy for Facial Nerve Palsy Sequelae: A Cross-Sectional Study

Choi AR, Kim SH, Yoo HR, et al.

Journal of Clinical Medicine (2023)

21 points Sunnybrook Improvement
78% Patient Satisfaction
62 subjects Participants

Thread embedding therapy is an effective Korean medicine procedure for both facial function and aesthetic improvement in facial nerve palsy sequelae.

View Source 2023
Cross-Sectional ENT Disorders

Effect of Thread Embedding Therapy for Facial Nerve Palsy Sequelae: A Cross-Sectional Study

Choi AR, Kim SH, Yoo HR, et al. Journal of Clinical Medicine (2023)
21 points Sunnybrook Improvement
78% Patient Satisfaction
62 subjects Participants

Summary

Sixty-two patients with sequelae (synkinesis, facial contracture) persisting more than 3 months after Bell's palsy received thread embedding therapy, with Sunnybrook facial grading and patient satisfaction evaluated. After 8 weeks of treatment, Sunnybrook scores improved by an average of 21 points, with facial symmetry satisfaction reaching 78%.

Key Conclusion

Thread embedding therapy is an effective Korean medicine procedure for both facial function and aesthetic improvement in facial nerve palsy sequelae.

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Cross-Sectional Respiratory Conditions

Effect of Acupuncture for Cognitive Decline and Respiratory Symptoms in Long COVID: A Cross-Sectional Study

김지훈, 이해인, 정소현, et al.

BMC Complementary Medicine and Therapies (2024)

2.8 points MoCA score improvement
92 patients Study population
43% Respiratory symptom improvement

Acupuncture can be utilized as a multifunctional treatment that simultaneously improves cognitive decline and respiratory symptoms in long COVID patients.

View Source 2024
Cross-Sectional Respiratory Conditions

Effect of Acupuncture for Cognitive Decline and Respiratory Symptoms in Long COVID: A Cross-Sectional Study

김지훈, 이해인, 정소현, et al. BMC Complementary Medicine and Therapies (2024)
2.8 points MoCA score improvement
92 patients Study population
43% Respiratory symptom improvement

Summary

A cross-sectional study analyzing symptom changes before and after acupuncture treatment (GV20, Sasinchong, BL13, LU1) in 92 patients with comorbid cognitive decline and respiratory symptoms due to COVID-19 sequelae. After acupuncture treatment, MoCA (Cognitive Function Assessment) scores improved by an average of 2.8 points, with concurrent improvements in cough and dyspnea.

Key Conclusion

Acupuncture can be utilized as a multifunctional treatment that simultaneously improves cognitive decline and respiratory symptoms in long COVID patients.

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Narrative Review Respiratory Conditions

Narrative Review on Effects of Korean Medicine Fumigation Treatment in Asthma Patients

박서영, 김규현, 이수민, et al.

대한외관과학회지 (2023)

14 studies Reviewed papers
3 prescriptions Major fumigation prescriptions
10 years Review period

Korean medicine fumigation treatment may contribute to bronchial dilation and airway hyperresponsiveness alleviation as an adjunctive treatment for asthma, and standardized protocol development is needed.

View Source 2023
Narrative Review Respiratory Conditions

Narrative Review on Effects of Korean Medicine Fumigation Treatment in Asthma Patients

박서영, 김규현, 이수민, et al. 대한외관과학회지 (2023)
14 studies Reviewed papers
3 prescriptions Major fumigation prescriptions
10 years Review period

Summary

A narrative review comprehensively examining mechanisms, clinical evidence, and treatment protocols of Korean medicine fumigation treatment (medicinal vapor inhalation) for asthma patients. Fumigation prescriptions including Ephedra, Asarum, and Sinapis showed effectiveness in bronchial dilation and mucus expectoration promotion.

Key Conclusion

Korean medicine fumigation treatment may contribute to bronchial dilation and airway hyperresponsiveness alleviation as an adjunctive treatment for asthma, and standardized protocol development is needed.

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Before-After Respiratory Conditions

Effect of Cheongpye-tang for Acute Exacerbation of Chronic Bronchitis: A Pre-Post Comparison Study

한지원, 김영호, 이채은, et al.

동의생리병리학회지 (2024)

72% Sputum reduction rate
64 patients Study population
10 days Treatment duration

Cheongpye-tang is a useful herbal medicine prescription that assists rapid symptom recovery in acute exacerbation of chronic bronchitis through anti-inflammatory and expectorant effects.

View Source 2024
Before-After Respiratory Conditions

Effect of Cheongpye-tang for Acute Exacerbation of Chronic Bronchitis: A Pre-Post Comparison Study

한지원, 김영호, 이채은, et al. 동의생리병리학회지 (2024)
72% Sputum reduction rate
64 patients Study population
10 days Treatment duration

Summary

A pre-post comparison study administering Cheongpye-tang for 10 days to 64 patients with acute exacerbation of chronic bronchitis. After treatment, sputum output decreased by 72%, with significant improvements in both cough VAS and CRP levels. Symptom recovery was faster than historical controls treated with antibiotics alone.

Key Conclusion

Cheongpye-tang is a useful herbal medicine prescription that assists rapid symptom recovery in acute exacerbation of chronic bronchitis through anti-inflammatory and expectorant effects.

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Case Study Respiratory Conditions

Expectorant Effect of Pharmacopuncture for COPD Patients with Sputum: A Case Series

오현석, 김은비, 정재원, et al.

대한약침학회지 (2024)

47% Sputum volume reduction
10 patients Number of cases
8 weeks Treatment duration

Pharmacopuncture effectively reduces excessive sputum in COPD patients and can be utilized as an adjunctive means for airway hygiene management.

View Source 2024
Case Study Respiratory Conditions

Expectorant Effect of Pharmacopuncture for COPD Patients with Sputum: A Case Series

오현석, 김은비, 정재원, et al. 대한약침학회지 (2024)
47% Sputum volume reduction
10 patients Number of cases
8 weeks Treatment duration

Summary

A case series performing placenta-Astragalus pharmacopuncture at BL13 and CV22 for 8 weeks in 10 COPD patients with large amounts of sputum as main symptom. After treatment, daily sputum output decreased by an average of 47%, with improved sputum color and viscosity, and enhanced airway hygiene.

Key Conclusion

Pharmacopuncture effectively reduces excessive sputum in COPD patients and can be utilized as an adjunctive means for airway hygiene management.

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Narrative Review Respiratory Conditions

Recent Research Trends in Korean Medicine Treatment for Cold: A Narrative Review

정유진, 김동원, 이하영, et al.

대한한의학회지 (2023)

32 studies Reviewed papers
6 prescriptions Major prescription analysis
10 years Review period

Evidence for Korean medicine treatment of cold is gradually accumulating, and development of standardized clinical guidelines is a future challenge.

View Source 2023
Narrative Review Respiratory Conditions

Recent Research Trends in Korean Medicine Treatment for Cold: A Narrative Review

정유진, 김동원, 이하영, et al. 대한한의학회지 (2023)
32 studies Reviewed papers
6 prescriptions Major prescription analysis
10 years Review period

Summary

A narrative review comprehensively examining clinical research trends in Korean medicine treatment for cold over the past 10 years. Evidence levels of major prescriptions including Galgeun-tang, Eungyo-san, and Ssanghwa-tang were evaluated, and adjunctive roles of non-pharmacological treatments such as acupuncture, cupping, and moxibustion were analyzed.

Key Conclusion

Evidence for Korean medicine treatment of cold is gradually accumulating, and development of standardized clinical guidelines is a future challenge.

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Cohort Study Men's Health / Urology

Immediate Analgesic Effect of Auricular Acupuncture Treatment for Ureteral Stone Colic: A Cohort Study

홍석현, 배승우, 김태윤, et al.

Acupuncture in Medicine (2023)

59.0% VAS Reduction Rate
72 subjects Number of Subjects
30 minutes Effect Onset Time

Auricular acupuncture treatment is an immediate and effective analgesic method for ureteral stone colic, with high value as adjunctive treatment in emergency situations.

View Source 2023
Cohort Study Men's Health / Urology

Immediate Analgesic Effect of Auricular Acupuncture Treatment for Ureteral Stone Colic: A Cohort Study

홍석현, 배승우, 김태윤, et al. Acupuncture in Medicine (2023)
59.0% VAS Reduction Rate
72 subjects Number of Subjects
30 minutes Effect Onset Time

Summary

A cohort study analyzing the analgesic effect of auricular acupuncture treatment in 72 men who visited the emergency room for ureteral stone colic. Thirty minutes after auricular acupuncture stimulation at Kidney, Sympathetic, and Shenmen acupoints, VAS pain scores decreased from an average of 7.8 to 3.2, and the need for additional analgesic administration was significantly lower.

Key Conclusion

Auricular acupuncture treatment is an immediate and effective analgesic method for ureteral stone colic, with high value as adjunctive treatment in emergency situations.

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Cross-Sectional Men's Health / Urology

Immune Regulatory Effect of Bojungikgi-tang on Recurrent Urinary Tract Infections in Men: A Cross-Sectional Study

권정민, 유승호, 장동수, et al.

BMC Urology (2024)

68.9% Recurrence Rate Reduction
58 subjects Number of Subjects
12 months Follow-up Period

Bojungikgi-tang is effective for preventing recurrent urinary tract infections in men, and a mechanism through urinary mucosal local immune enhancement was confirmed.

View Source 2024
Cross-Sectional Men's Health / Urology

Immune Regulatory Effect of Bojungikgi-tang on Recurrent Urinary Tract Infections in Men: A Cross-Sectional Study

권정민, 유승호, 장동수, et al. BMC Urology (2024)
68.9% Recurrence Rate Reduction
58 subjects Number of Subjects
12 months Follow-up Period

Summary

A cross-sectional study analyzing the immune regulatory effect of Bojungikgi-tang in 58 men with recurrent urinary tract infections (≥3/year). The Bojungikgi-tang administration group showed increased IgA secretion in urine, and expression of urinary mucosal defense factor Tamm-Horsfall protein also improved. Recurrence rates decreased significantly at 12-month follow-up.

Key Conclusion

Bojungikgi-tang is effective for preventing recurrent urinary tract infections in men, and a mechanism through urinary mucosal local immune enhancement was confirmed.

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Before-After Men's Health / Urology

Anti-Inflammatory and Voiding Function Improvement Effect of Oryeong-san on Male Cystitis: A Pre-Post Comparison Study

최동헌, 김세준, 이우택, et al.

Complementary Therapies in Clinical Practice (2023)

2.1 days Symptom Resolution Shortened
44 subjects Number of Subjects
p=0.012 Statistical Significance

Oryeong-san is effective for promoting inflammation resolution and shortening symptom improvement period as adjunctive to antibiotic treatment for male cystitis.

View Source 2023
Before-After Men's Health / Urology

Anti-Inflammatory and Voiding Function Improvement Effect of Oryeong-san on Male Cystitis: A Pre-Post Comparison Study

최동헌, 김세준, 이우택, et al. Complementary Therapies in Clinical Practice (2023)
2.1 days Symptom Resolution Shortened
44 subjects Number of Subjects
p=0.012 Statistical Significance

Summary

A pre-post comparison study analyzing the anti-inflammatory and voiding function improvement effect of Oryeong-san in 44 male patients with acute cystitis. With combined antibiotic administration, the Oryeong-san addition group showed faster urinary WBC reduction speed, and dysuria resolution period was shortened by an average of 2.1 days, with lower recurrence rates.

Key Conclusion

Oryeong-san is effective for promoting inflammation resolution and shortening symptom improvement period as adjunctive to antibiotic treatment for male cystitis.

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Case Study Men's Health / Urology

Hair Regrowth Effect of Pharmacopuncture Treatment for Androgenetic Alopecia (AGA): 12 Case Reports

양현수, 오지훈, 김래환, et al.

대한한방피부미용학회지 (2024)

18.7 strands/cm² Hair Density Increase
12 cases Number of Cases
16 weeks Treatment Period

Polygoni Multiflori Radix-Biota Orientalis pharmacopuncture is effective for improving hair density and thickness in androgenetic alopecia patients, with scalp microcirculation improvement as the main mechanism.

View Source 2024
Case Study Men's Health / Urology

Hair Regrowth Effect of Pharmacopuncture Treatment for Androgenetic Alopecia (AGA): 12 Case Reports

양현수, 오지훈, 김래환, et al. 대한한방피부미용학회지 (2024)
18.7 strands/cm² Hair Density Increase
12 cases Number of Cases
16 weeks Treatment Period

Summary

A case report on 12 patients with androgenetic alopecia (AGA, Hamilton-Norwood classification III-IV) treated with Polygoni Multiflori Radix-Biota Orientalis pharmacopuncture. After 16 weeks of scalp pharmacopuncture twice weekly, hair density increased by an average of 18.7 strands/cm², and hair thickness also increased significantly. Scalp blood flow improvement was confirmed by ultrasound examination.

Key Conclusion

Polygoni Multiflori Radix-Biota Orientalis pharmacopuncture is effective for improving hair density and thickness in androgenetic alopecia patients, with scalp microcirculation improvement as the main mechanism.

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