금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
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Total 1642 papers

RCT Digestive Disorders

Acupuncture Treatment for Stress-Related Irritable Bowel Syndrome with Anxiety: A Randomized Controlled Trial

Park BS, Kang JH, Lee EH, et al.

Neurogastroenterology & Motility (2023)

48% IBS symptoms↓
42% Anxiety↓
Gut-brain axis Mechanism

Acupuncture treatment simultaneously improves irritable bowel syndrome and accompanying anxiety through the gut-brain axis.

RCT Digestive Disorders

Acupuncture Treatment for Stress-Related Irritable Bowel Syndrome with Anxiety: A Randomized Controlled Trial

Park BS, Kang JH, Lee EH, et al. Neurogastroenterology & Motility (2023)
48% IBS symptoms↓
42% Anxiety↓
Gut-brain axis Mechanism

Summary

Eighty-five patients with comorbid IBS and anxiety were divided into acupuncture and sham acupuncture groups and compared for 8 weeks. Both IBS-SSS (-48%) and GAD-7 (-42%) significantly improved in the acupuncture group.

Key Conclusion

Acupuncture treatment simultaneously improves irritable bowel syndrome and accompanying anxiety through the gut-brain axis.

Meta-Analysis ENT Disorders

Meta-analysis of Korean Medicine Treatment for Pediatric Tonsillar and Adenoid Hypertrophy

Won JY, Choi SM, Lee MS, et al.

Pediatric Allergy and Immunology (2023)

18% A/N Ratio Reduction
9 studies Analyzed Studies
782 subjects Total Participants

Korean medicine treatment is an effective alternative for non-surgical management of pediatric tonsillar and adenoid hypertrophy.

Meta-Analysis ENT Disorders

Meta-analysis of Korean Medicine Treatment for Pediatric Tonsillar and Adenoid Hypertrophy

Won JY, Choi SM, Lee MS, et al. Pediatric Allergy and Immunology (2023)
18% A/N Ratio Reduction
9 studies Analyzed Studies
782 subjects Total Participants

Summary

Nine RCTs (782 subjects total) on Korean medicine treatment for pediatric tonsillar and adenoid hypertrophy were meta-analyzed. The herbal medicine (Hyungaeyongyo-tang, Bojungikgi-tang, etc.) administration group demonstrated an average 18% reduction in adenoid-to-nasopharynx (A/N) ratio, with significant improvement in snoring and mouth breathing symptoms.

Key Conclusion

Korean medicine treatment is an effective alternative for non-surgical management of pediatric tonsillar and adenoid hypertrophy.

RCT ENT Disorders

AHI Improvement Effect of Acupuncture for Obstructive Sleep Apnea: A Randomized Controlled Trial

Kim JE, Jung HJ, Park HJ, et al.

Sleep Medicine (2024)

38% AHI Reduction Rate
84 subjects Participants
p<0.001 Statistical Significance

Acupuncture is an effective complementary treatment for AHI reduction and daytime sleepiness improvement in obstructive sleep apnea.

RCT ENT Disorders

AHI Improvement Effect of Acupuncture for Obstructive Sleep Apnea: A Randomized Controlled Trial

Kim JE, Jung HJ, Park HJ, et al. Sleep Medicine (2024)
38% AHI Reduction Rate
84 subjects Participants
p<0.001 Statistical Significance

Summary

Eighty-four patients with moderate obstructive sleep apnea were assigned to acupuncture or sham acupuncture control groups for 8 weeks of treatment. The acupuncture group demonstrated an average 38% reduction in AHI (Apnea-Hypopnea Index), significantly superior to the sham group (12%), with also improvements in ESS (Epworth Sleepiness Scale).

Key Conclusion

Acupuncture is an effective complementary treatment for AHI reduction and daytime sleepiness improvement in obstructive sleep apnea.

Before-After ENT Disorders

Effect of Combined Electroacupuncture and Auricular Acupuncture for Snoring: A Pre-Post Comparison Study

Oh JY, Yang CS, Kang JH, et al.

대한한의학회지 (2023)

42% Snoring Intensity Reduction
6.8→3.2 Partner VAS
53 subjects Participants

Combined electroacupuncture and auricular acupuncture significantly reduces snoring intensity and is utilizable as a non-invasive treatment alternative.

Before-After ENT Disorders

Effect of Combined Electroacupuncture and Auricular Acupuncture for Snoring: A Pre-Post Comparison Study

Oh JY, Yang CS, Kang JH, et al. 대한한의학회지 (2023)
42% Snoring Intensity Reduction
6.8→3.2 Partner VAS
53 subjects Participants

Summary

Fifty-three patients with snoring received combined electroacupuncture at Renying (ST9) and Tiantu (CV22) plus auricular acupuncture (Internal Nose, Shenmen) three times weekly for 6 weeks. Snoring intensity (snoring index) decreased by an average of 42%, and partner-reported VAS improved from 6.8 to 3.2.

Key Conclusion

Combined electroacupuncture and auricular acupuncture significantly reduces snoring intensity and is utilizable as a non-invasive treatment alternative.

Systematic Review ENT Disorders

Systematic Review of Korean Medicine Treatment for Post-COVID-19 Olfactory Dysfunction

Lee SH, Chung JM, Ha IH, et al.

European Journal of Integrative Medicine (2024)

17 studies Reviewed Studies
8.4 points Olfactory Score Improvement
67% Complete Recovery Rate

Korean medicine combined treatment is an effective therapeutic strategy that promotes recovery in post-COVID-19 olfactory dysfunction.

Systematic Review ENT Disorders

Systematic Review of Korean Medicine Treatment for Post-COVID-19 Olfactory Dysfunction

Lee SH, Chung JM, Ha IH, et al. European Journal of Integrative Medicine (2024)
17 studies Reviewed Studies
8.4 points Olfactory Score Improvement
67% Complete Recovery Rate

Summary

Seventeen studies on Korean medicine treatment (acupuncture, herbal medicine, combined aromatherapy) for persistent olfactory dysfunction after COVID-19 infection were systematically reviewed. With combined acupuncture (Yingxiang, Shangxing, Yintang) and herbal medicines such as Tonggyu-tang, Sniffin Sticks scores improved by an average of 8.4 points, and recovery period was shortened.

Key Conclusion

Korean medicine combined treatment is an effective therapeutic strategy that promotes recovery in post-COVID-19 olfactory dysfunction.

Meta-Analysis ENT Disorders

Salivary Secretion Promotion Effect of Acupuncture for Xerostomia: A Meta-analysis

Sim HS, Cho HJ, Yoon HJ, et al.

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology (2023)

0.18 mL/min Salivary Flow Increase
14 studies Analyzed Studies
1,108 subjects Total Participants

Acupuncture is an effective treatment that simultaneously improves objective salivary flow and subjective symptoms in xerostomia patients.

Meta-Analysis ENT Disorders

Salivary Secretion Promotion Effect of Acupuncture for Xerostomia: A Meta-analysis

Sim HS, Cho HJ, Yoon HJ, et al. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology (2023)
0.18 mL/min Salivary Flow Increase
14 studies Analyzed Studies
1,108 subjects Total Participants

Summary

Fourteen RCTs (1,108 subjects total) evaluating acupuncture effects for xerostomia were meta-analyzed. The acupuncture group demonstrated an average 0.18 mL/min increase in unstimulated whole salivary flow rate (UWS), significantly higher than controls, with also significant improvement in subjective oral dryness (VAS).

Key Conclusion

Acupuncture is an effective treatment that simultaneously improves objective salivary flow and subjective symptoms in xerostomia patients.

Cohort Study ENT Disorders

Analysis of Prognostic Factors in Acute-Phase Korean Medicine Treatment for Bell's Palsy: A Cohort Study

Ko HJ, Nam BH, Yun JM, et al.

Neurology (2024)

89% Early Treatment Complete Recovery
183 subjects Participants
72 hours Recommended Onset

Korean medicine treatment for Bell's palsy demonstrates significantly better prognosis with early intervention, and treatment initiation within 72 hours of onset is recommended.

Cohort Study ENT Disorders

Analysis of Prognostic Factors in Acute-Phase Korean Medicine Treatment for Bell's Palsy: A Cohort Study

Ko HJ, Nam BH, Yun JM, et al. Neurology (2024)
89% Early Treatment Complete Recovery
183 subjects Participants
72 hours Recommended Onset

Summary

One hundred eighty-three patients with acute-phase Bell's palsy received combined acupuncture, electroacupuncture, and herbal medicine (modified Uchashinki-hwan), with House-Brackmann (HB) grade changes and prognostic factors analyzed. The complete recovery rate (HB I) was 89% in patients starting treatment within 3 days of onset, significantly higher than 62% in those starting after 7 days.

Key Conclusion

Korean medicine treatment for Bell's palsy demonstrates significantly better prognosis with early intervention, and treatment initiation within 72 hours of onset is recommended.

RCT ENT Disorders

Pain Alleviation Effect of Electroacupuncture for Trigeminal Neuralgia: A Randomized Controlled Trial

Jeong HJ, Park SJ, Kim YI, et al.

Pain Medicine (2023)

55% BPI Reduction Rate
68 subjects Participants
6 weeks Treatment Period

Electroacupuncture demonstrates equivalent efficacy to carbamazepine for pain alleviation in trigeminal neuralgia, with fewer side effects as an alternative.

RCT ENT Disorders

Pain Alleviation Effect of Electroacupuncture for Trigeminal Neuralgia: A Randomized Controlled Trial

Jeong HJ, Park SJ, Kim YI, et al. Pain Medicine (2023)
55% BPI Reduction Rate
68 subjects Participants
6 weeks Treatment Period

Summary

Sixty-eight patients with trigeminal neuralgia were assigned to electroacupuncture or carbamazepine monotherapy groups for 6 weeks of treatment. The electroacupuncture group demonstrated a 55% reduction in BPI (Brief Pain Inventory) scores, equivalent to the medication group (48%), with significantly lower adverse event rates.

Key Conclusion

Electroacupuncture demonstrates equivalent efficacy to carbamazepine for pain alleviation in trigeminal neuralgia, with fewer side effects as an alternative.

Cohort Study Respiratory Conditions

Safety and Efficacy of Long-Term Bopye-tang Administration in Elderly with Reduced Pulmonary Function: A Cohort Study

조수현, 김영진, 박지수, et al.

대한한방내과학회지 (2024)

8.7% FEV1 improvement
88 patients Study population
24 weeks Treatment duration

Long-term Bopye-tang administration is a safe Korean medicine treatment that slows the progression of reduced pulmonary function in the elderly and improves systemic physical strength.

Cohort Study Respiratory Conditions

Safety and Efficacy of Long-Term Bopye-tang Administration in Elderly with Reduced Pulmonary Function: A Cohort Study

조수현, 김영진, 박지수, et al. 대한한방내과학회지 (2024)
8.7% FEV1 improvement
88 patients Study population
24 weeks Treatment duration

Summary

A prospective cohort study administering and observing Bopye-tang for 24 weeks in 88 elderly aged 65 or older with reduced pulmonary function (FEV1 predicted 60-80%). After treatment, FEV1 improved by an average of 8.7%, with reduced COPD acute exacerbations and improved overall physical strength indicators.

Key Conclusion

Long-term Bopye-tang administration is a safe Korean medicine treatment that slows the progression of reduced pulmonary function in the elderly and improves systemic physical strength.

RCT Respiratory Conditions

Effect of Acupuncture for Patients with Anxiety Disorder Accompanied by Dyspnea: A Randomized Controlled Trial

김하은, 정민규, 이승아, et al.

Journal of Acupuncture and Meridian Studies (2023)

1.4 points mMRC scale improvement
76 patients Study population
48% BAI score reduction

Acupuncture is an effective non-pharmacological treatment that simultaneously improves both symptoms in patients with comorbid dyspnea and anxiety.

RCT Respiratory Conditions

Effect of Acupuncture for Patients with Anxiety Disorder Accompanied by Dyspnea: A Randomized Controlled Trial

김하은, 정민규, 이승아, et al. Journal of Acupuncture and Meridian Studies (2023)
1.4 points mMRC scale improvement
76 patients Study population
48% BAI score reduction

Summary

A randomized controlled trial comparing acupuncture at PC6, HT7, BL13 versus sham acupuncture in 76 patients with comorbid dyspnea and anxiety disorder. After 6 weeks, the acupuncture group showed significantly improved mMRC dyspnea scale, with concurrent reduction in BAI (anxiety scale).

Key Conclusion

Acupuncture is an effective non-pharmacological treatment that simultaneously improves both symptoms in patients with comorbid dyspnea and anxiety.

Case Study ENT Disorders

Recurrence Prevention Effect of Korean Medicine Combination Treatment for Recurrent Tonsillitis: A Case Report

한서윤, 정우진, 김태리, et al.

한방안이비인후피부과학회지 (2023)

73% Recurrence reduction rate
9 patients Number of cases
6 months Treatment duration

Korean medicine combination treatment markedly reduces recurrence rate in recurrent tonsillitis patients and may serve as an alternative to surgical treatment.

Case Study ENT Disorders

Recurrence Prevention Effect of Korean Medicine Combination Treatment for Recurrent Tonsillitis: A Case Report

한서윤, 정우진, 김태리, et al. 한방안이비인후피부과학회지 (2023)
73% Recurrence reduction rate
9 patients Number of cases
6 months Treatment duration

Summary

A case report performing herbal medicine (modified Bangpungtongseong-san), acupuncture, and pharmacopuncture for 6 months in 9 patients with recurrent tonsillitis (4 or more times annually). Tonsillitis recurrence decreased by an average of 73% during treatment period, with improvements in tonsillar hypertrophy grade.

Key Conclusion

Korean medicine combination treatment markedly reduces recurrence rate in recurrent tonsillitis patients and may serve as an alternative to surgical treatment.

Narrative Review ENT Disorders

Recent Trends in Korean Medicine Treatment for Postnasal Drip Syndrome: A Narrative Review

이다현, 김상우, 박혜린, et al.

대한한의학회지 (2024)

18 studies Reviewed papers
8 prescriptions Major herbal prescriptions
5 years Review period

Korean medicine treatment for postnasal drip syndrome focuses on nasal secretion regulation and mucosal function recovery, with effective integrative approach.

Narrative Review ENT Disorders

Recent Trends in Korean Medicine Treatment for Postnasal Drip Syndrome: A Narrative Review

이다현, 김상우, 박혜린, et al. 대한한의학회지 (2024)
18 studies Reviewed papers
8 prescriptions Major herbal prescriptions
5 years Review period

Summary

A narrative review comprehensively analyzing Korean medicine pathophysiological interpretation and treatment of postnasal drip syndrome. Clinical evidence for nasal prescriptions including Magnoliae flos and Xanthii fructus was analyzed, along with adjunctive effects of nasal irrigation and fumigation. A total of 18 related studies were reviewed.

Key Conclusion

Korean medicine treatment for postnasal drip syndrome focuses on nasal secretion regulation and mucosal function recovery, with effective integrative approach.