금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
🔍

Total 1642 papers

RCT Digestive Disorders

Gastric Motility Promotion Effect of Abdominal Chuna for Functional Dyspepsia: A Randomized Controlled Trial

Lee SG, Kwak MA, Jung SY, et al.

Neurogastroenterology & Motility (2024)

28 minutes Gastric Emptying↑
52% Symptoms↓
70 subjects Participants

Abdominal chuna manipulation improves dyspepsia by directly promoting gastric motility.

RCT Digestive Disorders

Gastric Motility Promotion Effect of Abdominal Chuna for Functional Dyspepsia: A Randomized Controlled Trial

Lee SG, Kwak MA, Jung SY, et al. Neurogastroenterology & Motility (2024)
28 minutes Gastric Emptying↑
52% Symptoms↓
70 subjects Participants

Summary

Seventy patients with functional dyspepsia were compared over 6 weeks between abdominal chuna and sham acupuncture groups. The chuna group showed gastric emptying half-time shortened by 28 minutes and FD symptoms improved by 52%.

Key Conclusion

Abdominal chuna manipulation improves dyspepsia by directly promoting gastric motility.

Before-After Digestive Disorders

High-Resolution Esophageal Manometry Study of Acupuncture for Esophageal Motility in GERD Patients: A Pre-Post Comparison

Roh JD, Kim GH, Park HJ, et al.

Esophagus (2023)

22% LES Pressure↑
35 subjects Participants
Peristalsis↑ Esophageal Motility

Acupuncture alleviates GERD by strengthening the lower esophageal sphincter and improving esophageal motility.

Before-After Digestive Disorders

High-Resolution Esophageal Manometry Study of Acupuncture for Esophageal Motility in GERD Patients: A Pre-Post Comparison

Roh JD, Kim GH, Park HJ, et al. Esophagus (2023)
22% LES Pressure↑
35 subjects Participants
Peristalsis↑ Esophageal Motility

Summary

Thirty-five GERD patients underwent high-resolution manometry (HRM) before and after 8 sessions of acupuncture. Lower esophageal sphincter pressure increased by 22% and esophageal peristalsis improved.

Key Conclusion

Acupuncture alleviates GERD by strengthening the lower esophageal sphincter and improving esophageal motility.

Cohort Study Digestive Disorders

Cohort Study of Sogeonjung-tang for Pediatric Abdominal Pain

Ahn YJ, Kim CH, Choi SY, et al.

Pediatric Gastroenterology (2024)

81% Pain Frequency↓
75 subjects Participants
12 weeks Follow-up Period

Sogeonjung-tang is an effective herbal treatment for pediatric recurrent abdominal pain.

Cohort Study Digestive Disorders

Cohort Study of Sogeonjung-tang for Pediatric Abdominal Pain

Ahn YJ, Kim CH, Choi SY, et al. Pediatric Gastroenterology (2024)
81% Pain Frequency↓
75 subjects Participants
12 weeks Follow-up Period

Summary

Seventy-five children with recurrent abdominal pain were followed for 12 weeks, divided into Sogeonjung-tang and non-treatment groups. The herbal group showed abdominal pain frequency decreasing from 4.2 to 0.8 per week, with improved school attendance.

Key Conclusion

Sogeonjung-tang is an effective herbal treatment for pediatric recurrent abdominal pain.

Cross-Sectional Digestive Disorders

Korean Medicine Intervention for the Correlation Between Abdominal Obesity and Digestive Symptoms: A Cross-Sectional Analysis

Shin JH, Kang YH, Oh MS, et al.

Obesity Research (2023)

220 subjects Participants
Abdominal circumference↓ Obesity Improvement
Digestion↑ Symptom Improvement

Korean medicine intervention simultaneously manages abdominal obesity and comorbid digestive symptoms.

Cross-Sectional Digestive Disorders

Korean Medicine Intervention for the Correlation Between Abdominal Obesity and Digestive Symptoms: A Cross-Sectional Analysis

Shin JH, Kang YH, Oh MS, et al. Obesity Research (2023)
220 subjects Participants
Abdominal circumference↓ Obesity Improvement
Digestion↑ Symptom Improvement

Summary

The effect of Korean medicine intervention was analyzed in 220 adults with abdominal obesity (waist circumference ≥90 cm M / 85 cm F) and comorbid digestive symptoms. The herbal medicine plus acupuncture group showed simultaneous improvement in abdominal circumference and digestive symptoms.

Key Conclusion

Korean medicine intervention simultaneously manages abdominal obesity and comorbid digestive symptoms.

Meta-Analysis Digestive Disorders

Meta-analysis of Acupuncture for Postoperative Ileus After Digestive Surgery

Lee SY, Go GY, Park JK, et al.

Surgery (2023)

20 RCTs Analyzed RCTs
18 hours Defecation↑
12 hours Flatus↑

Acupuncture effectively promotes intestinal function recovery after digestive surgery.

Meta-Analysis Digestive Disorders

Meta-analysis of Acupuncture for Postoperative Ileus After Digestive Surgery

Lee SY, Go GY, Park JK, et al. Surgery (2023)
20 RCTs Analyzed RCTs
18 hours Defecation↑
12 hours Flatus↑

Summary

Twenty RCTs evaluating the effect of acupuncture on postoperative ileus after digestive surgery were meta-analyzed. The acupuncture group showed time to first defecation shortened by 18 hours and time to first flatus shortened by 12 hours.

Key Conclusion

Acupuncture effectively promotes intestinal function recovery after digestive surgery.

RCT Digestive Disorders

Brain Imaging Study of Moxibustion for Irritable Bowel Syndrome: A Randomized Controlled Trial

Jeon SW, Min BW, Cha YR, et al.

NeuroImage (2023)

48% IBS-SSS↓
45 subjects Participants
Brain connectivity↑ Neural Modulation

Moxibustion improves IBS symptoms by modulating brain-gut neural circuits.

RCT Digestive Disorders

Brain Imaging Study of Moxibustion for Irritable Bowel Syndrome: A Randomized Controlled Trial

Jeon SW, Min BW, Cha YR, et al. NeuroImage (2023)
48% IBS-SSS↓
45 subjects Participants
Brain connectivity↑ Neural Modulation

Summary

Forty-five IBS patients were compared over 6 weeks between moxibustion and sham moxibustion groups, with fMRI assessment. The moxibustion group demonstrated a 48% reduction in IBS-SSS along with significant improvement in prefrontal-amygdala connectivity.

Key Conclusion

Moxibustion improves IBS symptoms by modulating brain-gut neural circuits.

Systematic Review Digestive Disorders

Systematic Review of Medicinal Diet Therapy for Gastrointestinal Symptoms

Kim EH, Yoo SR, Cho AR, et al.

Nutrition Reviews (2024)

15 studies Analyzed Papers
Ginger·Jujube Active Ingredients
Digestion promotion Main Effect

Medicinal diet therapy is effective as adjunctive management of digestive symptoms.

Systematic Review Digestive Disorders

Systematic Review of Medicinal Diet Therapy for Gastrointestinal Symptoms

Kim EH, Yoo SR, Cho AR, et al. Nutrition Reviews (2024)
15 studies Analyzed Papers
Ginger·Jujube Active Ingredients
Digestion promotion Main Effect

Summary

Fifteen studies evaluating the effect of medicinal diet (yaksun) therapy on gastrointestinal symptoms were systematically reviewed. Medicinal diets based on ginger, jujube, and Chinese yam demonstrated efficacy in promoting digestion and alleviating abdominal pain.

Key Conclusion

Medicinal diet therapy is effective as adjunctive management of digestive symptoms.

Narrative Review Digestive Disorders

Narrative Review of Saam Acupuncture for Digestive Disorders

Cho WS, Park EJ, Lee JY, et al.

Journal of Acupuncture Research (2023)

18 papers Reviewed Papers
Spleen Formula Main Prescription
Saam Acupuncture Acupuncture System

Saam acupuncture provides an independent theoretical framework for Korean medicine acupuncture treatment of digestive disorders.

Narrative Review Digestive Disorders

Narrative Review of Saam Acupuncture for Digestive Disorders

Cho WS, Park EJ, Lee JY, et al. Journal of Acupuncture Research (2023)
18 papers Reviewed Papers
Spleen Formula Main Prescription
Saam Acupuncture Acupuncture System

Summary

Eighteen articles on the theory and clinical application of Saam acupuncture for digestive disorders were reviewed. Spleen-Stomach tonification and sedation (Spleen-Tonifying Formula, Stomach-Tonifying Formula) demonstrated consistent effects on dyspepsia and abdominal pain.

Key Conclusion

Saam acupuncture provides an independent theoretical framework for Korean medicine acupuncture treatment of digestive disorders.

RCT Digestive Disorders

Randomized Controlled Trial of Sogeonjung-tang for Pediatric Constipation

Son HY, Kim MJ, Park EJ, et al.

Journal of Pediatric Gastroenterology and Nutrition (2023)

5.2/week Defecation↑
60 subjects Participants
Pain↓ Additional Effect

Sogeonjung-tang is effective in improving defecation frequency and alleviating abdominal pain in pediatric functional constipation.

RCT Digestive Disorders

Randomized Controlled Trial of Sogeonjung-tang for Pediatric Constipation

Son HY, Kim MJ, Park EJ, et al. Journal of Pediatric Gastroenterology and Nutrition (2023)
5.2/week Defecation↑
60 subjects Participants
Pain↓ Additional Effect

Summary

Sixty children with functional constipation were compared over 8 weeks between Sogeonjung-tang and placebo groups. The herbal group showed weekly spontaneous bowel movements increasing from 1.8 to 5.2, with reduced abdominal pain.

Key Conclusion

Sogeonjung-tang is effective in improving defecation frequency and alleviating abdominal pain in pediatric functional constipation.

Case Study Digestive Disorders

Case Report of Daesiho-tang for Gallstone Disease

Lim JH, Shin BC, Kim CH, et al.

Journal of Hepato-Biliary-Pancreatic Sciences (2024)

8 cases Case Number
3 cleared Gallstone Removal
16 weeks Treatment Period

Daesiho-tang may contribute to size reduction and disappearance of small gallstones.

Case Study Digestive Disorders

Case Report of Daesiho-tang for Gallstone Disease

Lim JH, Shin BC, Kim CH, et al. Journal of Hepato-Biliary-Pancreatic Sciences (2024)
8 cases Case Number
3 cleared Gallstone Removal
16 weeks Treatment Period

Summary

Eight patients with gallstones received Daesiho-tang for 16 weeks in a reported case series. Five patients showed gallstone size reduction of 30% or more, and three patients had complete gallstone disappearance.

Key Conclusion

Daesiho-tang may contribute to size reduction and disappearance of small gallstones.

RCT Digestive Disorders

Randomized Controlled Trial of Herbal Sitz Bath and Topical Agents for Hemorrhoids

Go GY, Han SH, Park BS, et al.

Diseases of the Colon & Rectum (2023)

62% Bleeding↓
55% Pain↓
70 subjects Participants

Herbal sitz bath and topical agents are effective non-surgical treatments for early-stage hemorrhoids.

RCT Digestive Disorders

Randomized Controlled Trial of Herbal Sitz Bath and Topical Agents for Hemorrhoids

Go GY, Han SH, Park BS, et al. Diseases of the Colon & Rectum (2023)
62% Bleeding↓
55% Pain↓
70 subjects Participants

Summary

Seventy patients with internal hemorrhoids (Grade I-II) were compared over 6 weeks between herbal sitz bath plus topical and suppository groups. The Korean medicine group showed equivalent improvement in bleeding frequency (-62%) and pain (-55%) compared to suppositories.

Key Conclusion

Herbal sitz bath and topical agents are effective non-surgical treatments for early-stage hemorrhoids.

Cohort Study Digestive Disorders

Mucosal Healing Effect of Combined Herbal Medicine and PPI for Gastric Ulcer: A Cohort Study

Cha YR, Woo HS, Nam DH, et al.

European Journal of Gastroenterology & Hepatology (2024)

88% Healing Rate
95 subjects Participants
PPI Combination Treatment Strategy

Combined herbal medicine and PPI improves the healing rate of gastric ulcers.

Cohort Study Digestive Disorders

Mucosal Healing Effect of Combined Herbal Medicine and PPI for Gastric Ulcer: A Cohort Study

Cha YR, Woo HS, Nam DH, et al. European Journal of Gastroenterology & Hepatology (2024)
88% Healing Rate
95 subjects Participants
PPI Combination Treatment Strategy

Summary

Ninety-five patients with gastric ulcer were followed for 8 weeks, divided into PPI plus herbal medicine (Hwangnyeonhaedok-tang) and PPI-alone groups. The combined group showed an ulcer healing rate of 88%, significantly higher than 72% in the monotherapy group.

Key Conclusion

Combined herbal medicine and PPI improves the healing rate of gastric ulcers.