금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
🔍

Total 1642 papers

Meta-Analysis Digestive Disorders

Meta-analysis of Acupuncture for Postoperative Ileus After Digestive Surgery

Lee SY, Go GY, Park JK, et al.

Surgery (2023)

20 RCTs Analyzed RCTs
18 hours Defecation↑
12 hours Flatus↑

Acupuncture effectively promotes intestinal function recovery after digestive surgery.

Meta-Analysis Digestive Disorders

Meta-analysis of Acupuncture for Postoperative Ileus After Digestive Surgery

Lee SY, Go GY, Park JK, et al. Surgery (2023)
20 RCTs Analyzed RCTs
18 hours Defecation↑
12 hours Flatus↑

Summary

Twenty RCTs evaluating the effect of acupuncture on postoperative ileus after digestive surgery were meta-analyzed. The acupuncture group showed time to first defecation shortened by 18 hours and time to first flatus shortened by 12 hours.

Key Conclusion

Acupuncture effectively promotes intestinal function recovery after digestive surgery.

Cross-Sectional Digestive Disorders

Korean Medicine Intervention for the Correlation Between Abdominal Obesity and Digestive Symptoms: A Cross-Sectional Analysis

Shin JH, Kang YH, Oh MS, et al.

Obesity Research (2023)

220 subjects Participants
Abdominal circumference↓ Obesity Improvement
Digestion↑ Symptom Improvement

Korean medicine intervention simultaneously manages abdominal obesity and comorbid digestive symptoms.

Cross-Sectional Digestive Disorders

Korean Medicine Intervention for the Correlation Between Abdominal Obesity and Digestive Symptoms: A Cross-Sectional Analysis

Shin JH, Kang YH, Oh MS, et al. Obesity Research (2023)
220 subjects Participants
Abdominal circumference↓ Obesity Improvement
Digestion↑ Symptom Improvement

Summary

The effect of Korean medicine intervention was analyzed in 220 adults with abdominal obesity (waist circumference ≥90 cm M / 85 cm F) and comorbid digestive symptoms. The herbal medicine plus acupuncture group showed simultaneous improvement in abdominal circumference and digestive symptoms.

Key Conclusion

Korean medicine intervention simultaneously manages abdominal obesity and comorbid digestive symptoms.

Cohort Study Digestive Disorders

Cohort Study of Sogeonjung-tang for Pediatric Abdominal Pain

Ahn YJ, Kim CH, Choi SY, et al.

Pediatric Gastroenterology (2024)

81% Pain Frequency↓
75 subjects Participants
12 weeks Follow-up Period

Sogeonjung-tang is an effective herbal treatment for pediatric recurrent abdominal pain.

Cohort Study Digestive Disorders

Cohort Study of Sogeonjung-tang for Pediatric Abdominal Pain

Ahn YJ, Kim CH, Choi SY, et al. Pediatric Gastroenterology (2024)
81% Pain Frequency↓
75 subjects Participants
12 weeks Follow-up Period

Summary

Seventy-five children with recurrent abdominal pain were followed for 12 weeks, divided into Sogeonjung-tang and non-treatment groups. The herbal group showed abdominal pain frequency decreasing from 4.2 to 0.8 per week, with improved school attendance.

Key Conclusion

Sogeonjung-tang is an effective herbal treatment for pediatric recurrent abdominal pain.

Before-After Digestive Disorders

High-Resolution Esophageal Manometry Study of Acupuncture for Esophageal Motility in GERD Patients: A Pre-Post Comparison

Roh JD, Kim GH, Park HJ, et al.

Esophagus (2023)

22% LES Pressure↑
35 subjects Participants
Peristalsis↑ Esophageal Motility

Acupuncture alleviates GERD by strengthening the lower esophageal sphincter and improving esophageal motility.

Before-After Digestive Disorders

High-Resolution Esophageal Manometry Study of Acupuncture for Esophageal Motility in GERD Patients: A Pre-Post Comparison

Roh JD, Kim GH, Park HJ, et al. Esophagus (2023)
22% LES Pressure↑
35 subjects Participants
Peristalsis↑ Esophageal Motility

Summary

Thirty-five GERD patients underwent high-resolution manometry (HRM) before and after 8 sessions of acupuncture. Lower esophageal sphincter pressure increased by 22% and esophageal peristalsis improved.

Key Conclusion

Acupuncture alleviates GERD by strengthening the lower esophageal sphincter and improving esophageal motility.

RCT Digestive Disorders

Gastric Motility Promotion Effect of Abdominal Chuna for Functional Dyspepsia: A Randomized Controlled Trial

Lee SG, Kwak MA, Jung SY, et al.

Neurogastroenterology & Motility (2024)

28 minutes Gastric Emptying↑
52% Symptoms↓
70 subjects Participants

Abdominal chuna manipulation improves dyspepsia by directly promoting gastric motility.

RCT Digestive Disorders

Gastric Motility Promotion Effect of Abdominal Chuna for Functional Dyspepsia: A Randomized Controlled Trial

Lee SG, Kwak MA, Jung SY, et al. Neurogastroenterology & Motility (2024)
28 minutes Gastric Emptying↑
52% Symptoms↓
70 subjects Participants

Summary

Seventy patients with functional dyspepsia were compared over 6 weeks between abdominal chuna and sham acupuncture groups. The chuna group showed gastric emptying half-time shortened by 28 minutes and FD symptoms improved by 52%.

Key Conclusion

Abdominal chuna manipulation improves dyspepsia by directly promoting gastric motility.

Systematic Review Digestive Disorders

Updated Systematic Review of Moxibustion for Digestive Symptoms

Cho AR, Park MJ, Kim DI, et al.

BMC Complementary Medicine (2023)

28 studies Analyzed Papers
Multi-symptom application Versatility
Whole digestive system Application Scope

Moxibustion is an effective treatment universally applicable to various digestive symptoms.

Systematic Review Digestive Disorders

Updated Systematic Review of Moxibustion for Digestive Symptoms

Cho AR, Park MJ, Kim DI, et al. BMC Complementary Medicine (2023)
28 studies Analyzed Papers
Multi-symptom application Versatility
Whole digestive system Application Scope

Summary

Twenty-eight studies evaluating the effect of moxibustion on digestive symptoms were systematically reviewed. Moxibustion demonstrated significant improvement effects on dyspepsia, abdominal pain, constipation, and diarrhea.

Key Conclusion

Moxibustion is an effective treatment universally applicable to various digestive symptoms.

Cohort Study Digestive Disorders

Correlation Between Stress and Gut Symptoms in IBS Patients: An Acupuncture Effect Cohort

Hwang MS, Yoo JH, Cho HJ, et al.

Psychosomatic Medicine (2023)

35% Stress↓
42% IBS-SSS↓
110 subjects Participants

Acupuncture improves IBS by interrupting the vicious cycle of stress and gut symptoms.

Cohort Study Digestive Disorders

Correlation Between Stress and Gut Symptoms in IBS Patients: An Acupuncture Effect Cohort

Hwang MS, Yoo JH, Cho HJ, et al. Psychosomatic Medicine (2023)
35% Stress↓
42% IBS-SSS↓
110 subjects Participants

Summary

One hundred ten IBS patients were followed for 12 weeks, divided into acupuncture and non-treatment groups. The acupuncture group demonstrated significant reductions in PSS stress (-35%) and IBS-SSS (-42%).

Key Conclusion

Acupuncture improves IBS by interrupting the vicious cycle of stress and gut symptoms.

RCT Digestive Disorders

Randomized Controlled Trial of Transcutaneous Electrical Stimulation at Neiguan for Motion Sickness

Go JH, Park HJ, Lee SH, et al.

Aviation, Space and Environmental Medicine (2024)

62% Symptoms↓
50 subjects Participants
Gastric rhythm normalization Mechanism

Transcutaneous electrical stimulation at Neiguan is effective in preventing motion sickness.

RCT Digestive Disorders

Randomized Controlled Trial of Transcutaneous Electrical Stimulation at Neiguan for Motion Sickness

Go JH, Park HJ, Lee SH, et al. Aviation, Space and Environmental Medicine (2024)
62% Symptoms↓
50 subjects Participants
Gastric rhythm normalization Mechanism

Summary

Fifty adults with motion sickness tendency were compared between Neiguan transcutaneous stimulation and placebo groups. The stimulation group demonstrated a 62% reduction in motion sickness symptom scores and normalized gastric dysrhythmia.

Key Conclusion

Transcutaneous electrical stimulation at Neiguan is effective in preventing motion sickness.

Narrative Review Digestive Disorders

Brain-Gut Axis Modulation by Acupuncture for Chronic Abdominal Pain: A Narrative Review

Shin SM, Bae GE, Kim KW, et al.

Pain Research & Management (2023)

20 papers Reviewed Papers
ACC modulation Central Mechanism
Serotonin Gut Mechanism

Acupuncture modulates chronic abdominal pain at multiple levels of the brain-gut axis.

Narrative Review Digestive Disorders

Brain-Gut Axis Modulation by Acupuncture for Chronic Abdominal Pain: A Narrative Review

Shin SM, Bae GE, Kim KW, et al. Pain Research & Management (2023)
20 papers Reviewed Papers
ACC modulation Central Mechanism
Serotonin Gut Mechanism

Summary

Twenty articles on the brain-gut axis modulation mechanism of acupuncture for chronic abdominal pain were reviewed. Acupuncture demonstrated effects on ACC (anterior cingulate cortex) activity modulation and intestinal serotonin homeostasis restoration.

Key Conclusion

Acupuncture modulates chronic abdominal pain at multiple levels of the brain-gut axis.

RCT Digestive Disorders

Randomized Controlled Trial of Injinssuk-tang for Liver Function Improvement

Bae HS, Choi HS, Lee KH, et al.

Journal of Hepatology (2024)

52% ALT↓
45% GGT↓
80 subjects Participants

Injinssuk-tang demonstrates equivalent efficacy to silymarin in improving liver function.

RCT Digestive Disorders

Randomized Controlled Trial of Injinssuk-tang for Liver Function Improvement

Bae HS, Choi HS, Lee KH, et al. Journal of Hepatology (2024)
52% ALT↓
45% GGT↓
80 subjects Participants

Summary

Eighty patients with abnormal liver function (elevated ALT) were compared over 12 weeks between Injinssuk-tang and silymarin groups. The herbal group showed equivalent reductions in ALT (-52%) and GGT (-45%) compared to silymarin.

Key Conclusion

Injinssuk-tang demonstrates equivalent efficacy to silymarin in improving liver function.

Cross-Sectional Digestive Disorders

Predictive Model of Gut Microbiota and Herbal Medicine Treatment Response: A Cross-Sectional Analysis

Kang YH, Moon SJ, Cho WS, et al.

Microbiome (2023)

250 subjects Participants
78% Predictive Accuracy
P/B ratio Predictive Marker

Gut microbiota analysis can be utilized for personalized herbal medicine prescription.

Cross-Sectional Digestive Disorders

Predictive Model of Gut Microbiota and Herbal Medicine Treatment Response: A Cross-Sectional Analysis

Kang YH, Moon SJ, Cho WS, et al. Microbiome (2023)
250 subjects Participants
78% Predictive Accuracy
P/B ratio Predictive Marker

Summary

Gut microbiota composition and herbal medicine treatment response were analyzed in 250 patients with digestive disorders to develop a predictive model. The Prevotella/Bacteroides ratio predicted herbal treatment response with 78% accuracy.

Key Conclusion

Gut microbiota analysis can be utilized for personalized herbal medicine prescription.

Meta-Analysis Digestive Disorders

Effect of Auricular Acupuncture for Acid Reflux: A Meta-analysis

Yoo SR, Lee SY, Kim KW, et al.

Complementary Therapies in Medicine (2024)

12 RCTs Analyzed RCTs
-2.8 episodes Reflux↓/week
Auricular acupuncture Treatment Method

Auricular acupuncture is an effective non-pharmacological management option for acid reflux.

Meta-Analysis Digestive Disorders

Effect of Auricular Acupuncture for Acid Reflux: A Meta-analysis

Yoo SR, Lee SY, Kim KW, et al. Complementary Therapies in Medicine (2024)
12 RCTs Analyzed RCTs
-2.8 episodes Reflux↓/week
Auricular acupuncture Treatment Method

Summary

Twelve RCTs evaluating the effect of auricular acupuncture on acid reflux were meta-analyzed. Auricular acupuncture (Stomach point, Esophagus point) demonstrated significant effects on reduced reflux frequency (MD: -2.8 episodes/week) and GERD-Q score improvement.

Key Conclusion

Auricular acupuncture is an effective non-pharmacological management option for acid reflux.