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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Cross-Sectional Women's Health / Infertility

Impact of Pharmacopuncture Treatment on Hormonal Balance in Women with Oligomenorrhea: A Cross-Sectional Study

오지현, 임수아, 배소연, et al.

한방재활의학과학회지 (2024)

92 patients Study population
Normalized FSH/LH ratio
Significant Estradiol improvement

Pharmacopuncture treatment positively affects hypothalamic-pituitary-ovarian axis function modulation in women with oligomenorrhea and also contributes to stress hormone regulation.

View Source 2024
Cross-Sectional Women's Health / Infertility

Impact of Pharmacopuncture Treatment on Hormonal Balance in Women with Oligomenorrhea: A Cross-Sectional Study

오지현, 임수아, 배소연, et al. 한방재활의학과학회지 (2024)
92 patients Study population
Normalized FSH/LH ratio
Significant Estradiol improvement

Summary

A cross-sectional study analyzing hormonal changes from pharmacopuncture (Angelica, Cnidium pharmacopuncture) treatment in 92 women with oligomenorrhea (cycle 40 days or longer). The pharmacopuncture treatment experience group showed FSH/LH ratio closer to normal range, with significantly higher estradiol levels. Stress-related cortisol levels also tended to be lower.

Key Conclusion

Pharmacopuncture treatment positively affects hypothalamic-pituitary-ovarian axis function modulation in women with oligomenorrhea and also contributes to stress hormone regulation.

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Systematic Review Women's Health / Infertility

Effect of Acupuncture for Endometriosis-Related Pain: A Systematic Review

정서연, 김민주, 박유진, et al.

Acupuncture in Medicine (2024)

2.8 points VAS pain reduction
15 studies Analyzed studies
1,284 patients Total participants

Acupuncture is effective for non-pharmacological management of endometriosis-related pain and is an alternative that can avoid side effects of existing hormone treatments.

View Source 2024
Systematic Review Women's Health / Infertility

Effect of Acupuncture for Endometriosis-Related Pain: A Systematic Review

정서연, 김민주, 박유진, et al. Acupuncture in Medicine (2024)
2.8 points VAS pain reduction
15 studies Analyzed studies
1,284 patients Total participants

Summary

Fifteen RCTs (total 1,284 patients) evaluating acupuncture effects on chronic pelvic pain related to endometriosis were systematically reviewed. The acupuncture group showed average 2.8-point reduction in chronic pelvic pain VAS scores, with also significantly alleviated dyspareunia and dyschezia. Adverse events were markedly fewer compared to GnRH agonists.

Key Conclusion

Acupuncture is effective for non-pharmacological management of endometriosis-related pain and is an alternative that can avoid side effects of existing hormone treatments.

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RCT Women's Health / Infertility

Pain and Menstrual Volume Improvement Effect of Korean Medicine Combination Treatment for Adenomyosis: A Randomized Controlled Trial

서은지, 문하영, 권소희, et al.

BMC Complementary Medicine and Therapies (2024)

68% Pain reduction rate
22% Recurrence rate
96 patients Study population

Korean medicine combination treatment shows effects similar to GnRH agonists for pain management of adenomyosis, with lower recurrence rates favoring long-term management.

View Source 2024
RCT Women's Health / Infertility

Pain and Menstrual Volume Improvement Effect of Korean Medicine Combination Treatment for Adenomyosis: A Randomized Controlled Trial

서은지, 문하영, 권소희, et al. BMC Complementary Medicine and Therapies (2024)
68% Pain reduction rate
22% Recurrence rate
96 patients Study population

Summary

An RCT comparing combined herbal medicine (modified Sobokchugeo-tang) and acupuncture therapy with GnRH agonists in 96 women diagnosed with adenomyosis. After 6 months of treatment, pain reduction rate in the Korean medicine combination treatment group (68%) was similar to the GnRH group (72%), but recurrence rate after treatment completion was markedly lower in the Korean medicine group (22%) compared to GnRH group (58%).

Key Conclusion

Korean medicine combination treatment shows effects similar to GnRH agonists for pain management of adenomyosis, with lower recurrence rates favoring long-term management.

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Cohort Study Women's Health / Infertility

Recurrence Prevention Effect of Vaginal Fumigation Therapy for Chronic Vaginitis: A Prospective Cohort Study

임채린, 고유진, 신예은, et al.

대한한방부인과학회지 (2023)

18.3% Recurrence rate (fumigation)
124 patients Study population
23.6%p Recurrence rate difference

Vaginal fumigation therapy significantly reduces recurrence rates of chronic recurrent vaginitis and contributes to normalization of vaginal microbial environment.

View Source 2023
Cohort Study Women's Health / Infertility

Recurrence Prevention Effect of Vaginal Fumigation Therapy for Chronic Vaginitis: A Prospective Cohort Study

임채린, 고유진, 신예은, et al. 대한한방부인과학회지 (2023)
18.3% Recurrence rate (fumigation)
124 patients Study population
23.6%p Recurrence rate difference

Summary

A 6-month cohort study comparing vaginal fumigation combination group (62 patients) and antibiotic alone group (62 patients) in 124 women with recurrent vaginitis. Six-month recurrence rate in the vaginal fumigation combination group was 18.3%, significantly lower than the antibiotic alone group (41.9%), with also restored normal lactobacilli ratio in the vagina.

Key Conclusion

Vaginal fumigation therapy significantly reduces recurrence rates of chronic recurrent vaginitis and contributes to normalization of vaginal microbial environment.

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Cross-Sectional Women's Health / Infertility

Pain Relief and Quality of Life Improvement Effect of Chuna Treatment for Chronic Pelvic Pain: A Cross-Sectional Study

김다은, 이서진, 박하늘, et al.

Journal of Bodywork and Movement Therapies (2024)

3.2 points Chuna group NRS pain
78 patients Study population
2.6 points NRS score difference

Chuna treatment shows positive association with pain reduction and quality of life improvement in women with chronic pelvic pain, suggesting utility of musculoskeletal approach.

View Source 2024
Cross-Sectional Women's Health / Infertility

Pain Relief and Quality of Life Improvement Effect of Chuna Treatment for Chronic Pelvic Pain: A Cross-Sectional Study

김다은, 이서진, 박하늘, et al. Journal of Bodywork and Movement Therapies (2024)
3.2 points Chuna group NRS pain
78 patients Study population
2.6 points NRS score difference

Summary

A cross-sectional study comparing pain levels and quality of life between Chuna treatment experience and non-experience groups in 78 women with chronic pelvic pain. The Chuna treatment experience group had significantly lower pelvic pain NRS scores (3.2 vs 5.8), with also high scores in all SF-36 quality of life domains.

Key Conclusion

Chuna treatment shows positive association with pain reduction and quality of life improvement in women with chronic pelvic pain, suggesting utility of musculoskeletal approach.

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Meta-Analysis Women's Health / Infertility

Effect of Acupuncture for Menopausal Hot Flashes: A Systematic Review and Meta-Analysis

이주은, 김현서, 정다인, et al.

Menopause (2024)

8.4/week Flash frequency reduction
20 studies Analyzed studies
2,156 patients Total participants

Acupuncture significantly reduces frequency and severity of menopausal hot flashes and is an effective alternative for women who cannot use HRT.

View Source 2024
Meta-Analysis Women's Health / Infertility

Effect of Acupuncture for Menopausal Hot Flashes: A Systematic Review and Meta-Analysis

이주은, 김현서, 정다인, et al. Menopause (2024)
8.4/week Flash frequency reduction
20 studies Analyzed studies
2,156 patients Total participants

Summary

Twenty RCTs (total 2,156 patients) evaluating acupuncture effects on menopausal hot flashes were meta-analyzed. The acupuncture group showed an average 8.4 reduction in hot flash frequency per week, with also significantly alleviated severity. Showed similar effects to hormone replacement therapy (HRT) with almost no side effects.

Key Conclusion

Acupuncture significantly reduces frequency and severity of menopausal hot flashes and is an effective alternative for women who cannot use HRT.

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Cohort Study Women's Health / Infertility

Effect of Korean Medicine Combination Treatment for Menopausal Depression Symptoms: A Cohort Study

나현정, 유서영, 문지원, et al.

Journal of Affective Disorders (2024)

54.5% BDI score reduction rate
134 patients Study population
16 weeks Treatment duration

Korean medicine combination treatment shows effects equivalent to SSRIs for improving menopausal depression symptoms and is a treatment option with less side effect burden.

View Source 2024
Cohort Study Women's Health / Infertility

Effect of Korean Medicine Combination Treatment for Menopausal Depression Symptoms: A Cohort Study

나현정, 유서영, 문지원, et al. Journal of Affective Disorders (2024)
54.5% BDI score reduction rate
134 patients Study population
16 weeks Treatment duration

Summary

A cohort study evaluating effects of combined herbal medicine (modified Gwibi-tang) and acupuncture therapy in 134 women with menopausal depression symptoms (BDI 14 or higher). After 16 weeks of treatment, BDI scores decreased from an average of 21.3 to 9.7, with also significantly improved anxiety (BAI) scores. Showed equivalent effects compared to SSRI users.

Key Conclusion

Korean medicine combination treatment shows effects equivalent to SSRIs for improving menopausal depression symptoms and is a treatment option with less side effect burden.

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RCT Women's Health / Infertility

Sleep Improvement Effect of Electroacupuncture Treatment for Menopausal Insomnia: A Randomized Controlled Trial

심유나, 전하영, 양수빈, et al.

Sleep Medicine (2023)

52% PSQI improvement rate
89% Post-treatment sleep efficiency
96 patients Study population

Electroacupuncture treatment improves both subjective and objective sleep indicators of menopausal insomnia and is effective as a sleep medication alternative.

View Source 2023
RCT Women's Health / Infertility

Sleep Improvement Effect of Electroacupuncture Treatment for Menopausal Insomnia: A Randomized Controlled Trial

심유나, 전하영, 양수빈, et al. Sleep Medicine (2023)
52% PSQI improvement rate
89% Post-treatment sleep efficiency
96 patients Study population

Summary

An RCT comparing electroacupuncture treatment (HT7, EX-HN3, GV20) and sham acupuncture in 96 women with menopausal insomnia. After 8 weeks of treatment, PSQI total scores in the electroacupuncture group improved from 14.2 to 6.8, with sleep latency shortened by an average of 28 minutes. Objective sleep efficiency measured by actigraphy also improved from 78% to 89%.

Key Conclusion

Electroacupuncture treatment improves both subjective and objective sleep indicators of menopausal insomnia and is effective as a sleep medication alternative.

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Before-After Women's Health / Infertility

Bone Density Changes with Combined Acupuncture and Exercise Therapy in Women with Osteopenia: A Pre-Post Comparison Study

천서현, 구예린, 하소은, et al.

대한한의학회지 (2023)

2.4% Lumbar BMD increase
72 patients Study population
1.8% Femoral BMD increase

Combined acupuncture and exercise is an effective non-pharmacological strategy for bone density improvement and fall risk reduction in women with osteopenia.

View Source 2023
Before-After Women's Health / Infertility

Bone Density Changes with Combined Acupuncture and Exercise Therapy in Women with Osteopenia: A Pre-Post Comparison Study

천서현, 구예린, 하소은, et al. 대한한의학회지 (2023)
2.4% Lumbar BMD increase
72 patients Study population
1.8% Femoral BMD increase

Summary

A 12-month pre-post comparison study combining acupuncture (BL23, BL11, GB39) and weight-bearing exercise in 72 postmenopausal women with osteopenia (T-score -1.0 to -2.5). Lumbar BMD increased by an average of 2.4%, with femoral BMD also increasing by 1.8%. Fall risk assessment scores also significantly improved.

Key Conclusion

Combined acupuncture and exercise is an effective non-pharmacological strategy for bone density improvement and fall risk reduction in women with osteopenia.

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Case Study Women's Health / Infertility

Anti-Inflammatory Effect of Korean Medicine Treatment for Acute Mastitis: A Case Series

문서영, 채은비, 위소담, et al.

대한한방부인과학회지 (2024)

5.2 days Mean recovery duration
15 patients Number of cases
1.8 days Recovery shortened days

Korean medicine combination treatment promotes inflammation resolution of acute mastitis and increases recovery speed when combined with antibiotics.

View Source 2024
Case Study Women's Health / Infertility

Anti-Inflammatory Effect of Korean Medicine Treatment for Acute Mastitis: A Case Series

문서영, 채은비, 위소담, et al. 대한한방부인과학회지 (2024)
5.2 days Mean recovery duration
15 patients Number of cases
1.8 days Recovery shortened days

Summary

A combined herbal medicine (Taraxacum and Trichosanthes seed modified prescription) and acupuncture (RN17, ST18, SI1) treatment case in 15 women with acute mastitis during lactation. After average 5.2 days of treatment, fever resolved with breast swelling and erythema resolved. Symptom resolution time was an average 1.8 days faster than antibiotic alone treatment.

Key Conclusion

Korean medicine combination treatment promotes inflammation resolution of acute mastitis and increases recovery speed when combined with antibiotics.

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Systematic Review Women's Health / Infertility

Nausea and Vomiting Relief Effect of Ginger-Based Herbal Medicine for Hyperemesis Gravidarum: A Systematic Review

윤다영, 김하경, 이서현, et al.

Journal of Obstetrics and Gynaecology Research (2023)

48% Nausea reduction rate
14 studies Analyzed studies
1,186 patients Total participants

Ginger-based herbal medicine is effective for nausea and vomiting relief of hyperemesis gravidarum and is a treatment with confirmed fetal safety.

View Source 2023
Systematic Review Women's Health / Infertility

Nausea and Vomiting Relief Effect of Ginger-Based Herbal Medicine for Hyperemesis Gravidarum: A Systematic Review

윤다영, 김하경, 이서현, et al. Journal of Obstetrics and Gynaecology Research (2023)
48% Nausea reduction rate
14 studies Analyzed studies
1,186 patients Total participants

Summary

Fourteen RCTs (1,186 patients) evaluating effects of ginger-based herbal medicine (Sobanha-Gabokryeong-tang, etc.) treatment for hyperemesis gravidarum were systematically reviewed. Nausea severity (Rhodes Index) decreased by an average of 48% in the herbal medicine administration group, with vomiting frequency decreasing from an average of 3.2 to 0.8 times per day. No negative effects were observed on fetal safety indicators.

Key Conclusion

Ginger-based herbal medicine is effective for nausea and vomiting relief of hyperemesis gravidarum and is a treatment with confirmed fetal safety.

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RCT Women's Health / Infertility

Safety and Effect of Acupuncture for Pregnancy Low Back Pain: A Randomized Controlled Trial

한예지, 구다현, 성유미, et al.

Spine (2024)

63% Low back pain reduction rate
110 patients Study population
22%p Superiority over physiotherapy

Acupuncture is more effective than physiotherapy for low back pain during pregnancy and is a non-pharmacological pain management with confirmed fetal safety.

View Source 2024
RCT Women's Health / Infertility

Safety and Effect of Acupuncture for Pregnancy Low Back Pain: A Randomized Controlled Trial

한예지, 구다현, 성유미, et al. Spine (2024)
63% Low back pain reduction rate
110 patients Study population
22%p Superiority over physiotherapy

Summary

An RCT comparing acupuncture and physiotherapy in 110 pregnant women with low back pain at 20-34 weeks gestation. After 6 weeks of treatment, low back pain VAS scores decreased by 63% in the acupuncture group, superior to the physiotherapy group (41%). Oswestry Disability Index (ODI) also significantly improved, with no fetal-related adverse effects reported.

Key Conclusion

Acupuncture is more effective than physiotherapy for low back pain during pregnancy and is a non-pharmacological pain management with confirmed fetal safety.

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