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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Cohort Study Respiratory Conditions

Effect of Korean Medicine Combination Therapy on Asthma Attack Prevention in Children: A Cohort Study

Kim EJ, Lee SH, Yoon HJ, et al.

Pediatric Allergy and Immunology (2023)

67% Acute exacerbation reduction
38% Steroid use reduction
124 patients Study population

Korean medicine combination therapy is effective as adjunctive treatment for reducing acute exacerbation frequency and lowering steroid dependence in pediatric asthma.

View Source 2023
Cohort Study Respiratory Conditions

Effect of Korean Medicine Combination Therapy on Asthma Attack Prevention in Children: A Cohort Study

Kim EJ, Lee SH, Yoon HJ, et al. Pediatric Allergy and Immunology (2023)
67% Acute exacerbation reduction
38% Steroid use reduction
124 patients Study population

Summary

A 2-year cohort study following 124 pediatric asthma patients. The herbal medicine plus acupuncture combination group showed annual acute exacerbation frequency decreased from 1.8 to 0.6 episodes (67% reduction) and average 38% reduction in inhaled steroid use. Pulmonary function tests (FEV1) also showed significant improvement.

Key Conclusion

Korean medicine combination therapy is effective as adjunctive treatment for reducing acute exacerbation frequency and lowering steroid dependence in pediatric asthma.

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Systematic Review Respiratory Conditions

Systematic Review of Herbal Medicine Treatment for Chronic Cough

Jiang M, Lu C, Zhang C, et al.

Journal of Ethnopharmacology (2022)

63% Cough frequency reduction
14 studies Analyzed studies
8+ weeks Target cough duration

Herbal medicine treatment shows significant efficacy for chronic cough, particularly intractable cough of unknown origin, making it suitable for patients unresponsive to conventional treatments.

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Systematic Review Respiratory Conditions

Systematic Review of Herbal Medicine Treatment for Chronic Cough

Jiang M, Lu C, Zhang C, et al. Journal of Ethnopharmacology (2022)
63% Cough frequency reduction
14 studies Analyzed studies
8+ weeks Target cough duration

Summary

Fourteen clinical studies on herbal medicine treatment for chronic cough lasting more than 8 weeks were systematically reviewed. The herbal medicine group showed an average 63% reduction in cough frequency with significant improvement in cough-related quality of life (LCQ) scores. The efficacy was particularly notable in chronic cough of unknown origin.

Key Conclusion

Herbal medicine treatment shows significant efficacy for chronic cough, particularly intractable cough of unknown origin, making it suitable for patients unresponsive to conventional treatments.

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RCT ENT Disorders

Therapeutic Effect of Socheongryong-tang on Allergic Rhinitis: A Randomized Controlled Trial

Jung JW, Kang HR, Kim MH, et al.

Allergy, Asthma & Immunology Research (2023)

57% Nasal symptom reduction
94 patients Study population
4 weeks Treatment duration

Socheongryong-tang demonstrates symptom relief efficacy comparable to antihistamines for allergic rhinitis with fewer side effects, serving as a safe alternative treatment option.

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RCT ENT Disorders

Therapeutic Effect of Socheongryong-tang on Allergic Rhinitis: A Randomized Controlled Trial

Jung JW, Kang HR, Kim MH, et al. Allergy, Asthma & Immunology Research (2023)
57% Nasal symptom reduction
94 patients Study population
4 weeks Treatment duration

Summary

A randomized controlled trial comparing 4 weeks of Socheongryong-tang versus cetirizine alone in 94 patients with seasonal allergic rhinitis. The Socheongryong-tang group showed a 57% reduction in Total Nasal Symptom Score (TNSS), comparable to cetirizine (51%), while having significantly fewer side effects including drowsiness.

Key Conclusion

Socheongryong-tang demonstrates symptom relief efficacy comparable to antihistamines for allergic rhinitis with fewer side effects, serving as a safe alternative treatment option.

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RCT Digestive Disorders

Effect of Combined Acupuncture and Western Medicine for Reflux Esophagitis

Zhu JJ, Liu S, Chen WG, et al.

BMC Gastroenterology (2023)

68% Symptom Score Reduction
2 times PPI Reduction Success Rate
6 weeks Treatment Duration

Combined acupuncture and PPI is effective as an integrated treatment strategy that strengthens symptom relief in reflux esophagitis and reduces PPI dependence.

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RCT Digestive Disorders

Effect of Combined Acupuncture and Western Medicine for Reflux Esophagitis

Zhu JJ, Liu S, Chen WG, et al. BMC Gastroenterology (2023)
68% Symptom Score Reduction
2 times PPI Reduction Success Rate
6 weeks Treatment Duration

Summary

Eighty-six patients with reflux esophagitis were compared between a PPI monotherapy group and a PPI + acupuncture combined group over 6 weeks. The combined group showed a 68% reduction in RDQ (Reflux Disease Questionnaire) scores, demonstrating a significant difference compared to the monotherapy group (49%). Notably, the rate of successful PPI dose reduction was 2 times higher in the combined group.

Key Conclusion

Combined acupuncture and PPI is effective as an integrated treatment strategy that strengthens symptom relief in reflux esophagitis and reduces PPI dependence.

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RCT Digestive Disorders

Treatment Effect of Banhasasim-tang for Functional Dyspepsia: A Randomized Controlled Trial

Park JW, Ryu BH, Kim JS, et al.

Journal of Gastroenterology and Hepatology (2023)

61% Upper Abdominal Pain Reduction
54% Early Satiety Improvement
108 subjects Study Subjects

Banhasasim-tang significantly improves the major symptoms of functional dyspepsia and contributes to gastrointestinal motility recovery.

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RCT Digestive Disorders

Treatment Effect of Banhasasim-tang for Functional Dyspepsia: A Randomized Controlled Trial

Park JW, Ryu BH, Kim JS, et al. Journal of Gastroenterology and Hepatology (2023)
61% Upper Abdominal Pain Reduction
54% Early Satiety Improvement
108 subjects Study Subjects

Summary

An 8-week randomized controlled trial compared Banhasasim-tang with placebo in 108 patients with functional dyspepsia. The Banhasasim-tang group showed a 61% reduction in upper abdominal pain scores and a 54% improvement in early satiety. Significant improvement was also confirmed in gastric emptying function tests.

Key Conclusion

Banhasasim-tang significantly improves the major symptoms of functional dyspepsia and contributes to gastrointestinal motility recovery.

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Cohort Study Skin Conditions

Effect of Korean Medicine Combination Therapy in Psoriasis Patients: A Prospective Cohort Study

Yun YH, Choi JE, Kim KJ, et al.

Journal of Alternative and Complementary Medicine (2023)

41% PASI 75 achievement rate
62% Quality of life improvement
98 patients Study population

Korean medicine combination therapy contributes to reducing skin lesions and improving quality of life in psoriasis, with expected synergistic effects when combined with conventional treatment.

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Cohort Study Skin Conditions

Effect of Korean Medicine Combination Therapy in Psoriasis Patients: A Prospective Cohort Study

Yun YH, Choi JE, Kim KJ, et al. Journal of Alternative and Complementary Medicine (2023)
41% PASI 75 achievement rate
62% Quality of life improvement
98 patients Study population

Summary

A cohort study observing PASI score changes after 16 weeks of Korean medicine combination therapy combining herbal medicine and acupuncture in 98 patients with mild-to-moderate psoriasis. PASI 75 achievement rate was 41%, and patient-reported outcomes (DLQI) showed an average 62% improvement in quality of life.

Key Conclusion

Korean medicine combination therapy contributes to reducing skin lesions and improving quality of life in psoriasis, with expected synergistic effects when combined with conventional treatment.

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Systematic Review Skin Conditions

Systematic Review of Acupuncture Treatment for Chronic Urticaria

Lee HJ, Park YC, Kim KS, et al.

European Journal of Integrative Medicine (2022)

37% Additional symptom reduction
29% Recurrence reduction
11 studies Analyzed studies

Acupuncture as adjunctive treatment for chronic urticaria shows significant effects on symptom control and recurrence prevention.

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Systematic Review Skin Conditions

Systematic Review of Acupuncture Treatment for Chronic Urticaria

Lee HJ, Park YC, Kim KS, et al. European Journal of Integrative Medicine (2022)
37% Additional symptom reduction
29% Recurrence reduction
11 studies Analyzed studies

Summary

Eleven RCTs evaluating acupuncture treatment for chronic spontaneous urticaria were systematically analyzed. The acupuncture combination group showed an additional 37% reduction in UAS7 (urticaria activity score) compared to antihistamines alone, with 29% lower recurrence rates at 6-month follow-up.

Key Conclusion

Acupuncture as adjunctive treatment for chronic urticaria shows significant effects on symptom control and recurrence prevention.

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RCT Skin Conditions

Effect of Herbal Medicine Treatment for Atopic Dermatitis: A Randomized Controlled Trial

Choi IH, Kim S, Kim Y, et al.

Annals of Dermatology (2023)

48% SCORAD index reduction
55% Pruritus improvement
12 weeks Treatment duration

Herbal medicine treatment significantly improves skin lesions and pruritus in atopic dermatitis and may contribute to reducing steroid use.

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RCT Skin Conditions

Effect of Herbal Medicine Treatment for Atopic Dermatitis: A Randomized Controlled Trial

Choi IH, Kim S, Kim Y, et al. Annals of Dermatology (2023)
48% SCORAD index reduction
55% Pruritus improvement
12 weeks Treatment duration

Summary

Seventy-two patients with moderate atopic dermatitis were compared between herbal medicine and placebo groups for 12 weeks. The herbal medicine group showed an average 48% reduction in SCORAD index and 55% improvement in pruritus VAS. Serum IgE levels also significantly decreased, confirming immunomodulatory effects.

Key Conclusion

Herbal medicine treatment significantly improves skin lesions and pruritus in atopic dermatitis and may contribute to reducing steroid use.

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Before-After Mental Health

Pre-Post Comparison Study of Korean Medicine Combined Treatment for Panic Disorder Symptom Relief

Chung SY, Kim JH, Park JH, et al.

BMC Complementary Medicine and Therapies (2023)

58% Symptom Severity Reduction
81% Attack Frequency Reduction
56 subjects Study Participants

Korean medicine combined treatment significantly reduces the frequency and severity of panic disorder attacks and can be utilized as an adjunctive treatment strategy to reduce drug dependence.

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Before-After Mental Health

Pre-Post Comparison Study of Korean Medicine Combined Treatment for Panic Disorder Symptom Relief

Chung SY, Kim JH, Park JH, et al. BMC Complementary Medicine and Therapies (2023)
58% Symptom Severity Reduction
81% Attack Frequency Reduction
56 subjects Study Participants

Summary

A pre-post comparison study in which Korean medicine combined treatment combining acupuncture, herbal medicine, and relaxation therapy was administered for 8 weeks to 56 panic disorder patients. PDSS (Panic Disorder Severity Scale) decreased by 58% compared with pre-treatment, and panic attack frequency decreased from 4.2 to 0.8 times per week.

Key Conclusion

Korean medicine combined treatment significantly reduces the frequency and severity of panic disorder attacks and can be utilized as an adjunctive treatment strategy to reduce drug dependence.

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Meta-Analysis Mental Health

Treatment Effect of Acupuncture for Depression: A Systematic Review and Meta-Analysis

Smith CA, Armour M, Lee MS, et al.

Journal of Clinical Medicine (2022)

72% Treatment Response Rate
29 studies Analyzed Studies
2,268 subjects Total Participants

Acupuncture shows significant effects as adjunctive treatment for depression and can contribute to drug side effect reduction and treatment adherence improvement.

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Meta-Analysis Mental Health

Treatment Effect of Acupuncture for Depression: A Systematic Review and Meta-Analysis

Smith CA, Armour M, Lee MS, et al. Journal of Clinical Medicine (2022)
72% Treatment Response Rate
29 studies Analyzed Studies
2,268 subjects Total Participants

Summary

A meta-analysis of 29 randomized controlled trials (total 2,268 subjects) evaluating the depression treatment effect of acupuncture. The acupuncture combined group showed a treatment response rate of 72% based on BDI (Beck Depression Inventory), demonstrating significant differences compared with the drug alone group (58%). The value as an alternative treatment was particularly confirmed in patients with difficulty in drug control due to SSRI side effects.

Key Conclusion

Acupuncture shows significant effects as adjunctive treatment for depression and can contribute to drug side effect reduction and treatment adherence improvement.

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RCT Mental Health

Randomized Controlled Trial of Guibi-tang for Anxiety Disorder Treatment

Park YC, Kim SH, Jo HG, et al.

Journal of Affective Disorders (2023)

52% Anxiety Index Reduction
67% Insomnia Improvement Rate
12 weeks Treatment Period

Guibi-tang shows significant treatment effects on anxiety symptoms and accompanying insomnia in generalized anxiety disorder and also contributes to autonomic balance recovery.

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RCT Mental Health

Randomized Controlled Trial of Guibi-tang for Anxiety Disorder Treatment

Park YC, Kim SH, Jo HG, et al. Journal of Affective Disorders (2023)
52% Anxiety Index Reduction
67% Insomnia Improvement Rate
12 weeks Treatment Period

Summary

A randomized controlled trial comparing 12 weeks of Guibi-tang administration with placebo in 84 generalized anxiety disorder patients. The Guibi-tang group showed an average 52% reduction in HAM-A (Hamilton Anxiety Rating Scale) scores, with 67% improvement rate in accompanying insomnia symptoms. Heart rate variability (HRV) analysis showed significant increase in parasympathetic activity.

Key Conclusion

Guibi-tang shows significant treatment effects on anxiety symptoms and accompanying insomnia in generalized anxiety disorder and also contributes to autonomic balance recovery.

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Narrative Review Wellness / Restoration

Comparative Study of Active Component Extraction Rates by Herbal Decoction Temperature

Hwang JY, Bae KH, Song YR et al.

생약학회지 (2024)

+34% Glycoside Preservation Rate
+52% Essential Oil Preservation
+21% Total Efficacy Markers

Low-temperature extraction at 85°C preserved heat-sensitive glycosides and essential oil components an average of 34% more than high-temperature extraction at 100°C, with significantly superior total efficacy marker components.

2024
Narrative Review Wellness / Restoration

Comparative Study of Active Component Extraction Rates by Herbal Decoction Temperature

Hwang JY, Bae KH, Song YR et al. 생약학회지 (2024)
+34% Glycoside Preservation Rate
+52% Essential Oil Preservation
+21% Total Efficacy Markers

Summary

Active component contents of 20 major medicinal herbs were comparatively analyzed by HPLC under 70°C, 85°C, and 100°C extraction conditions.

Key Conclusion

Low-temperature extraction at 85°C preserved heat-sensitive glycosides and essential oil components an average of 34% more than high-temperature extraction at 100°C, with significantly superior total efficacy marker components.

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