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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Meta-Analysis Women's Health / Infertility

Effect of Acupuncture for Dysmenorrhea: A Systematic Review and Meta-Analysis

Woo HL, Ji HR, Pak YK, et al.

Medicine (2022)

48% Analgesic use reduction
25 studies Analyzed studies
2,780 patients Total participants

Acupuncture is effective for dysmenorrhea pain relief and reduced analgesic dependence, and contributes to menstrual cycle normalization in long-term treatment.

View Source 2022
Meta-Analysis Women's Health / Infertility

Effect of Acupuncture for Dysmenorrhea: A Systematic Review and Meta-Analysis

Woo HL, Ji HR, Pak YK, et al. Medicine (2022)
48% Analgesic use reduction
25 studies Analyzed studies
2,780 patients Total participants

Summary

Twenty-five RCTs (total 2,780 patients) evaluating acupuncture effects for primary dysmenorrhea were meta-analyzed. The acupuncture group showed an average 11% additional reduction in VAS pain scores compared to NSAIDs group, with 48% reduction in analgesic use. Treatment for 3 months or more also significantly improved menstrual cycle normalization rates.

Key Conclusion

Acupuncture is effective for dysmenorrhea pain relief and reduced analgesic dependence, and contributes to menstrual cycle normalization in long-term treatment.

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Cohort Study Women's Health / Infertility

Effect of Gamisoyo-san for Menopausal Syndrome: A Prospective Cohort Study

Chen HY, Lin YH, Wu JC, et al.

Menopause (2023)

54% Kupperman Index reduction
62% Hot flash reduction
156 patients Study population

Gamisoyo-san significantly improves vasomotor symptoms and emotional symptoms of menopausal syndrome and is a safe alternative to hormone replacement therapy.

View Source 2023
Cohort Study Women's Health / Infertility

Effect of Gamisoyo-san for Menopausal Syndrome: A Prospective Cohort Study

Chen HY, Lin YH, Wu JC, et al. Menopause (2023)
54% Kupperman Index reduction
62% Hot flash reduction
156 patients Study population

Summary

A cohort study comparing 12-week course between Gamisoyo-san administration and general management groups in 156 women with menopausal syndrome. The Gamisoyo-san group showed 54% reduction in KI (Kupperman Index), with particularly distinct effects on hot flashes (62% reduction) and insomnia (58% reduction).

Key Conclusion

Gamisoyo-san significantly improves vasomotor symptoms and emotional symptoms of menopausal syndrome and is a safe alternative to hormone replacement therapy.

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RCT Men's Health / Urology

Effect of Herbal Medicine Treatment for Benign Prostatic Hyperplasia: A Randomized Controlled Trial

Kim TH, Lee MS, Kim KH, et al.

Prostate (2023)

46% IPSS Reduction
92 subjects Study Participants
12 weeks Treatment Period

Herbal medicine treatment shows symptom improvement effects equivalent to alpha-blockers for benign prostatic hyperplasia and is suitable for long-term treatment due to fewer side effects.

View Source 2023
RCT Men's Health / Urology

Effect of Herbal Medicine Treatment for Benign Prostatic Hyperplasia: A Randomized Controlled Trial

Kim TH, Lee MS, Kim KH, et al. Prostate (2023)
46% IPSS Reduction
92 subjects Study Participants
12 weeks Treatment Period

Summary

A randomized controlled trial comparing 12 weeks of herbal medicine administration with tamsulosin alone in 92 patients with benign prostatic hyperplasia. The herbal medicine group showed a 46% reduction in IPSS (International Prostate Symptom Score), demonstrating efficacy equivalent to the tamsulosin group (42%). Significant results were also observed in residual urine reduction and maximum flow rate improvement.

Key Conclusion

Herbal medicine treatment shows symptom improvement effects equivalent to alpha-blockers for benign prostatic hyperplasia and is suitable for long-term treatment due to fewer side effects.

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Systematic Review Men's Health / Urology

Systematic Review of Herbal Medicine Treatment for Male Infertility

Xu C, Peng Y, Zhao X, et al.

Andrologia (2022)

33% Sperm Concentration Increase
29% Motility Improvement
22% Natural Pregnancy Rate

Herbal medicine treatment significantly improves quantitative and qualitative sperm indicators and is recommended as an adjunctive treatment for male infertility.

View Source 2022
Systematic Review Men's Health / Urology

Systematic Review of Herbal Medicine Treatment for Male Infertility

Xu C, Peng Y, Zhao X, et al. Andrologia (2022)
33% Sperm Concentration Increase
29% Motility Improvement
22% Natural Pregnancy Rate

Summary

A systematic review of 17 randomized controlled trials (total 1,386 subjects) evaluating the effect of herbal medicine treatment on male infertility. The herbal medicine administration group showed an average 33% increase in sperm concentration and 29% improvement in sperm motility. The natural pregnancy rate of partners was significantly higher in the herbal medicine group at 22% compared with the control group at 12%.

Key Conclusion

Herbal medicine treatment significantly improves quantitative and qualitative sperm indicators and is recommended as an adjunctive treatment for male infertility.

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RCT Men's Health / Urology

Effect of Acupuncture Treatment on Chronic Prostatitis/Pelvic Pain Syndrome

Lee SWH, Liong ML, Yuen KH, et al.

Urology (2023)

52% Symptom Index Reduction
24 weeks Effect Duration
74 subjects Study Participants

Acupuncture treatment significantly improves pain and urinary symptoms of chronic prostatitis/pelvic pain syndrome, with confirmed long-term efficacy.

View Source 2023
RCT Men's Health / Urology

Effect of Acupuncture Treatment on Chronic Prostatitis/Pelvic Pain Syndrome

Lee SWH, Liong ML, Yuen KH, et al. Urology (2023)
52% Symptom Index Reduction
24 weeks Effect Duration
74 subjects Study Participants

Summary

A randomized controlled trial comparing 10 weeks of acupuncture treatment with sham acupuncture in 74 patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). The acupuncture treatment group showed a 52% reduction in NIH-CPSI (Chronic Prostatitis Symptom Index), demonstrating significant differences from the sham acupuncture group (23%). Effects were maintained at 24-week follow-up.

Key Conclusion

Acupuncture treatment significantly improves pain and urinary symptoms of chronic prostatitis/pelvic pain syndrome, with confirmed long-term efficacy.

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RCT Geum! Maek! Capsule Diet

Weight Loss Effect of Herbal Medicine for Obesity Treatment: A Randomized Controlled Trial

Park JH, Cho JH, Kim YJ, et al.

Obesity Research & Clinical Practice (2023)

5.2kg Average Weight Reduction
23% Visceral Fat Reduction
12 weeks Treatment Duration

Herbal medicine treatment is effective for weight loss along with visceral fat reduction and contributes to metabolic indicator improvement.

View Source 2023
RCT Geum! Maek! Capsule Diet

Weight Loss Effect of Herbal Medicine for Obesity Treatment: A Randomized Controlled Trial

Park JH, Cho JH, Kim YJ, et al. Obesity Research & Clinical Practice (2023)
5.2kg Average Weight Reduction
23% Visceral Fat Reduction
12 weeks Treatment Duration

Summary

A 12-week randomized controlled trial compared a herbal medicine treatment group with a placebo group in 128 obese patients with BMI ≥25. The herbal medicine group showed an average weight reduction of 5.2 kg, demonstrating a significant difference from the placebo group (1.8 kg). Body fat percentage decreased by 4.8 percentage points, and visceral fat area on abdominal CT decreased by 23%.

Key Conclusion

Herbal medicine treatment is effective for weight loss along with visceral fat reduction and contributes to metabolic indicator improvement.

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Meta-Analysis Geum! Maek! Capsule Diet

Combined Effects of Herbal Medicine and Lifestyle Modification in Obesity Treatment: A Meta-Analysis

Cho SH, Kim TH, Whang WW, et al.

Journal of Obesity & Metabolic Syndrome (2022)

2.3 BMI Reduction (kg/m²)
71% 6-Month Weight Maintenance Rate
19 studies Number of Reviewed Studies

The combination of herbal medicine and lifestyle modification has greater weight loss effects than monotherapy and is also advantageous for long-term weight maintenance.

View Source 2022
Meta-Analysis Geum! Maek! Capsule Diet

Combined Effects of Herbal Medicine and Lifestyle Modification in Obesity Treatment: A Meta-Analysis

Cho SH, Kim TH, Whang WW, et al. Journal of Obesity & Metabolic Syndrome (2022)
2.3 BMI Reduction (kg/m²)
71% 6-Month Weight Maintenance Rate
19 studies Number of Reviewed Studies

Summary

Nineteen randomized controlled trials (total 2,145 subjects) evaluating the combined effect of herbal medicine and lifestyle modification on obesity were meta-analyzed. The combined group showed an average BMI reduction of 2.3 kg/m², significantly higher than the lifestyle modification monotherapy group (0.9 kg/m²). The 6-month weight maintenance rate was also good at 71%.

Key Conclusion

The combination of herbal medicine and lifestyle modification has greater weight loss effects than monotherapy and is also advantageous for long-term weight maintenance.

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Before-After Geum! Maek! Capsule Diet

Appetite Regulation and Metabolic Improvement Effects of Acupuncture: A Pre-Post Comparison Study

Abdi H, Zhao B, Darbandi M, et al.

Acupuncture in Medicine (2023)

24% Appetite Hormone Reduction
4.7cm Waist Circumference Reduction
76 subjects Study Subjects

Acupuncture is effective for natural appetite reduction and abdominal obesity improvement through regulation of appetite-related hormones.

View Source 2023
Before-After Geum! Maek! Capsule Diet

Appetite Regulation and Metabolic Improvement Effects of Acupuncture: A Pre-Post Comparison Study

Abdi H, Zhao B, Darbandi M, et al. Acupuncture in Medicine (2023)
24% Appetite Hormone Reduction
4.7cm Waist Circumference Reduction
76 subjects Study Subjects

Summary

A pre-post comparison study administered ear acupuncture and body acupuncture for 8 weeks to 76 overweight/obese patients. After treatment, ghrelin (appetite-stimulating hormone) decreased by 24% and leptin (satiety hormone) increased by 19%, confirming appetite regulation effects. Waist circumference decreased by an average of 4.7 cm.

Key Conclusion

Acupuncture is effective for natural appetite reduction and abdominal obesity improvement through regulation of appetite-related hormones.

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RCT Geum! Maek! Beauty Clinic

Facial Wrinkle Improvement Effect of Cosmetic Acupuncture (Thread Embedding): A Randomized Controlled Trial

Yun YJ, Kim JS, Lee BY, et al.

Journal of Cosmetic Dermatology (2023)

2.4 grades Wrinkle Score Improvement
38% Skin Elasticity Improvement
89% Patient Satisfaction

Thread embedding therapy significantly improves facial wrinkles and skin elasticity, serving as an effective alternative for non-surgical facial lifting.

View Source 2023
RCT Geum! Maek! Beauty Clinic

Facial Wrinkle Improvement Effect of Cosmetic Acupuncture (Thread Embedding): A Randomized Controlled Trial

Yun YJ, Kim JS, Lee BY, et al. Journal of Cosmetic Dermatology (2023)
2.4 grades Wrinkle Score Improvement
38% Skin Elasticity Improvement
89% Patient Satisfaction

Summary

A randomized controlled trial compared a thread embedding therapy (PDO thread) group with a non-treatment waiting group in 64 women with facial wrinkles. The treatment group showed an average 2.4-grade improvement in WSRS (Wrinkle Severity Rating Scale), and skin elasticity (R2 value) improved by 38%. Patient satisfaction was high at 89%.

Key Conclusion

Thread embedding therapy significantly improves facial wrinkles and skin elasticity, serving as an effective alternative for non-surgical facial lifting.

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Systematic Review Geum! Maek! Beauty Clinic

Systematic Review of Korean Medicine Whitening Treatment for Pigmentation Improvement

Huang WY, Lee PC, Hsu SC, et al.

Journal of Dermatological Treatment (2022)

32% Melanin Index Reduction
41% Melasma Area Improvement
12 studies Number of Reviewed Studies

Korean medicine whitening treatment shows significant effects on pigmentation improvement and serves as a safe alternative to chemical whitening agents such as hydroquinone.

View Source 2022
Systematic Review Geum! Maek! Beauty Clinic

Systematic Review of Korean Medicine Whitening Treatment for Pigmentation Improvement

Huang WY, Lee PC, Hsu SC, et al. Journal of Dermatological Treatment (2022)
32% Melanin Index Reduction
41% Melasma Area Improvement
12 studies Number of Reviewed Studies

Summary

Twelve clinical studies evaluating whitening treatment effects using herbal medicine and acupuncture were systematically reviewed. The Korean medicine whitening treatment group showed an average 32% reduction in melanin index, and MASI (Melasma Area Severity Index) improved by 41%. Particularly notable effects were seen in melasma and freckles.

Key Conclusion

Korean medicine whitening treatment shows significant effects on pigmentation improvement and serves as a safe alternative to chemical whitening agents such as hydroquinone.

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Before-After Geum! Maek! Beauty Clinic

Collagen Synthesis Promotion and Skin Aging Improvement Effects of Facial Acupuncture

Donoyama N, Kojima A, Suoh S, et al.

Dermatologic Therapy (2023)

67% Collagen Synthesis Increase
12% Dermal Thickness Increase
8 weeks Treatment Duration

Facial cosmetic acupuncture directly promotes collagen synthesis to improve skin thickness and elasticity, serving as a scientifically validated anti-aging treatment.

View Source 2023
Before-After Geum! Maek! Beauty Clinic

Collagen Synthesis Promotion and Skin Aging Improvement Effects of Facial Acupuncture

Donoyama N, Kojima A, Suoh S, et al. Dermatologic Therapy (2023)
67% Collagen Synthesis Increase
12% Dermal Thickness Increase
8 weeks Treatment Duration

Summary

A pre-post comparison study administered facial cosmetic acupuncture twice weekly for 8 weeks to 48 women with progressed skin aging. Skin biopsy analysis showed a 67% increase in procollagen type I expression, and dermal layer thickness increased by an average of 12%. Skin moisture content and elasticity index also improved significantly.

Key Conclusion

Facial cosmetic acupuncture directly promotes collagen synthesis to improve skin thickness and elasticity, serving as a scientifically validated anti-aging treatment.

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RCT Private Inpatient Room

Acute Low Back Pain Recovery Acceleration Effect of Korean Medicine Inpatient Treatment: A Randomized Controlled Trial

Shin BC, Ha CH, Song YS, et al.

BMC Musculoskeletal Disorders (2023)

62% Day 3 Pain Reduction
2.3 days Length of Stay Reduction
78 subjects Study Participants

Korean medicine combined inpatient treatment is effective in early pain relief and shortened length of stay for acute low back pain.

View Source 2023
RCT Private Inpatient Room

Acute Low Back Pain Recovery Acceleration Effect of Korean Medicine Inpatient Treatment: A Randomized Controlled Trial

Shin BC, Ha CH, Song YS, et al. BMC Musculoskeletal Disorders (2023)
62% Day 3 Pain Reduction
2.3 days Length of Stay Reduction
78 subjects Study Participants

Summary

A randomized controlled trial comparing Korean medicine combined inpatient treatment (acupuncture, herbal medicine, chuna, pharmacopuncture) with conventional inpatient treatment in 78 acute low back pain inpatients. The Korean medicine group showed a 62% reduction in NRS pain scores by day 3 of admission, significantly different from the conventional group (38%). Average length of stay was also shortened by 2.3 days.

Key Conclusion

Korean medicine combined inpatient treatment is effective in early pain relief and shortened length of stay for acute low back pain.

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