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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Cohort Study Gongjindan (拱辰丹)

Postoperative Recovery Promotion Effect of Gongjindan: A Prospective Cohort Study

Yoon JH, Kang DW, Lee SH, et al.

Integrative Medicine Research (2023)

48% Appetite Recovery Time Reduction
38% Physical Strength Improvement
126 subjects Participants

Gongjindan significantly accelerates postoperative recovery and contributes to nutritional status restoration and overall physical strength improvement.

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Cohort Study Gongjindan (拱辰丹)

Postoperative Recovery Promotion Effect of Gongjindan: A Prospective Cohort Study

Yoon JH, Kang DW, Lee SH, et al. Integrative Medicine Research (2023)
48% Appetite Recovery Time Reduction
38% Physical Strength Improvement
126 subjects Participants

Summary

A prospective cohort study compared recovery progress between Gongjindan and non-treatment groups in 126 patients after major surgery. The Gongjindan group recovered appetite in an average of 2.8 days (vs. 5.4 days in non-treatment), with serum albumin levels normalizing significantly faster. Self-reported physical strength assessment at 1 month post-discharge also showed 38% higher scores in the Gongjindan group.

Key Conclusion

Gongjindan significantly accelerates postoperative recovery and contributes to nutritional status restoration and overall physical strength improvement.

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Systematic Review Gongjindan (拱辰丹)

Antioxidant and Anti-inflammatory Synergistic Effects of Gongjindan Constituents: A Systematic Review

Kim HJ, Choi MK, Lee JH, et al.

Oxidative Medicine and Cellular Longevity (2022)

62% Antioxidant Enzyme Activity Increase
23 studies Analyzed Studies
4 herbs Synergistic Constituents

Combined use of Gongjindan constituents demonstrates antioxidant and anti-inflammatory synergistic effects compared to single use, providing pharmacological evidence for the systemic tonic effects of Gongjindan.

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Systematic Review Gongjindan (拱辰丹)

Antioxidant and Anti-inflammatory Synergistic Effects of Gongjindan Constituents: A Systematic Review

Kim HJ, Choi MK, Lee JH, et al. Oxidative Medicine and Cellular Longevity (2022)
62% Antioxidant Enzyme Activity Increase
23 studies Analyzed Studies
4 herbs Synergistic Constituents

Summary

Twenty-three basic and clinical studies evaluating antioxidant and anti-inflammatory effects of Gongjindan's four major constituents (deer antler, musk, Angelica, Cornus officinalis) were systematically reviewed. When pantocrine from deer antler combined with muscone from musk, SOD (antioxidant enzyme) activity increased by 62% compared to single use, with significant reduction in inflammatory markers including TNF-α. Synergistic effects were confirmed when 4 herbs were combined.

Key Conclusion

Combined use of Gongjindan constituents demonstrates antioxidant and anti-inflammatory synergistic effects compared to single use, providing pharmacological evidence for the systemic tonic effects of Gongjindan.

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RCT Gongjindan (拱辰丹)

Chronic Fatigue and Cognitive Function Improvement Effect of Gongjindan: A Randomized Controlled Trial

Park SJ, Kim SY, Lee BH, et al.

Journal of Ethnopharmacology (2023)

47% Fatigue Reduction
3.2 points Cognitive Score Improvement
8 weeks Treatment Period

Gongjindan simultaneously improves chronic fatigue and cognitive decline, with HPA axis normalization-mediated stress hormone modulation effects scientifically confirmed.

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RCT Gongjindan (拱辰丹)

Chronic Fatigue and Cognitive Function Improvement Effect of Gongjindan: A Randomized Controlled Trial

Park SJ, Kim SY, Lee BH, et al. Journal of Ethnopharmacology (2023)
47% Fatigue Reduction
3.2 points Cognitive Score Improvement
8 weeks Treatment Period

Summary

Eighty-eight adults with chronic fatigue were compared in a double-blind randomized controlled trial between Gongjindan and placebo groups over 8 weeks. The Gongjindan group demonstrated an average 47% reduction in FSS (Fatigue Severity Scale), with MoCA (Montreal Cognitive Assessment) scores improving by 3.2 points. Serum cortisol levels recovered to normal range, confirming HPA axis modulation effects.

Key Conclusion

Gongjindan simultaneously improves chronic fatigue and cognitive decline, with HPA axis normalization-mediated stress hormone modulation effects scientifically confirmed.

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Before-After Workers' Compensation

Effect of an Integrated Korean Medicine Program for Worker Rehabilitation After Industrial Accidents: A Pre-Post Comparison Study

Jung MY, Kim SG, Lee JH, et al.

Work (2023)

53% Disability Score Improvement
28% Grip Strength Increase
76% Return-to-Work Success Rate

An integrated Korean medicine rehabilitation program is effective for functional recovery and return-to-work in industrial accident workers.

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Before-After Workers' Compensation

Effect of an Integrated Korean Medicine Program for Worker Rehabilitation After Industrial Accidents: A Pre-Post Comparison Study

Jung MY, Kim SG, Lee JH, et al. Work (2023)
53% Disability Score Improvement
28% Grip Strength Increase
76% Return-to-Work Success Rate

Summary

A pre-post comparison study administering an integrated Korean medicine rehabilitation program (acupuncture, chuna, herbal medicine, exercise therapy) for 12 weeks to 68 workers in the rehabilitation phase after industrial accidents. DASH (Disabilities of the Arm, Shoulder, and Hand score) improved 53%, with grip strength increasing by an average of 28%. Return-to-work success rate after program completion reached 76%.

Key Conclusion

An integrated Korean medicine rehabilitation program is effective for functional recovery and return-to-work in industrial accident workers.

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Systematic Review Workers' Compensation

Effect of Acupuncture for Chronic Pain in Industrial Accident Patients: A Systematic Review

Qaseem A, Wilt TJ, McLean RM, et al.

Annals of Internal Medicine (2022)

35% Additional Pain Reduction
42% Analgesic Use Reduction
13 studies Studies Analyzed

Acupuncture is an effective adjunctive treatment for chronic pain management and reducing analgesic dependence in industrial accident patients.

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Systematic Review Workers' Compensation

Effect of Acupuncture for Chronic Pain in Industrial Accident Patients: A Systematic Review

Qaseem A, Wilt TJ, McLean RM, et al. Annals of Internal Medicine (2022)
35% Additional Pain Reduction
42% Analgesic Use Reduction
13 studies Studies Analyzed

Summary

A systematic review of 13 randomized controlled trials (total 1,124 subjects) evaluating the acupuncture effect for chronic pain caused by industrial accidents. The acupuncture group showed an additional average 35% reduction in pain scores, with a 42% decrease in analgesic use. Significant improvements were also confirmed in occupational function assessment.

Key Conclusion

Acupuncture is an effective adjunctive treatment for chronic pain management and reducing analgesic dependence in industrial accident patients.

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RCT Workers' Compensation

Effect of Korean Medicine Combined Treatment for Occupational Musculoskeletal Disorders: A Randomized Controlled Trial

Hwang MS, Heo KH, Cho HW, et al.

Journal of Occupational Health (2023)

59% Pain Reduction
82% Return-to-Work Rate
104 subjects Study Participants

Korean medicine combined treatment is effective for pain relief and return-to-work in occupational musculoskeletal disorders.

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RCT Workers' Compensation

Effect of Korean Medicine Combined Treatment for Occupational Musculoskeletal Disorders: A Randomized Controlled Trial

Hwang MS, Heo KH, Cho HW, et al. Journal of Occupational Health (2023)
59% Pain Reduction
82% Return-to-Work Rate
104 subjects Study Participants

Summary

A randomized controlled trial comparing Korean medicine combined treatment (acupuncture, chuna, herbal medicine) with conventional physical therapy for 10 weeks in 104 patients with work-related musculoskeletal disorders (WMSD). The Korean medicine group showed a 59% reduction in VAS pain scores, significantly different from the physical therapy group (37%). Return-to-work rate was also higher in the Korean medicine group at 82% versus the physical therapy group (64%).

Key Conclusion

Korean medicine combined treatment is effective for pain relief and return-to-work in occupational musculoskeletal disorders.

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Cohort Study Pediatric Traffic Accident

Functional Recovery Effect of Korean Medicine Rehabilitation for Pediatric Cervical Injury: A Cohort Study

Lee SG, Park JH, Kim MJ, et al.

Journal of Pediatric Rehabilitation Medicine (2023)

91% Cervical ROM recovery
12 weeks Treatment duration
72 patients Study population

Korean medicine rehabilitation promotes functional recovery of pediatric cervical injuries and is a safe treatment for growing patients.

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Cohort Study Pediatric Traffic Accident

Functional Recovery Effect of Korean Medicine Rehabilitation for Pediatric Cervical Injury: A Cohort Study

Lee SG, Park JH, Kim MJ, et al. Journal of Pediatric Rehabilitation Medicine (2023)
91% Cervical ROM recovery
12 weeks Treatment duration
72 patients Study population

Summary

A cohort study comparing 12-week course between Korean medicine rehabilitation and general rehabilitation groups in 72 pediatric patients with mild cervical injuries. The Korean medicine group showed 91% recovery of cervical ROM (range of motion), significantly higher than the general group (78%). Pain-related daily activity limitations also resolved faster in the Korean medicine group.

Key Conclusion

Korean medicine rehabilitation promotes functional recovery of pediatric cervical injuries and is a safe treatment for growing patients.

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Systematic Review Pediatric Traffic Accident

Effect of Acupuncture for Post-Traumatic Stress Response in Children: A Systematic Review

Yang J, Ganesh R, Bray BC, et al.

Children (2022)

41% Impact scale reduction
8 studies Analyzed studies
486 patients Total participants

Acupuncture is a safe adjunctive treatment for alleviating post-traumatic stress response in children, minimizing medication use.

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Systematic Review Pediatric Traffic Accident

Effect of Acupuncture for Post-Traumatic Stress Response in Children: A Systematic Review

Yang J, Ganesh R, Bray BC, et al. Children (2022)
41% Impact scale reduction
8 studies Analyzed studies
486 patients Total participants

Summary

Eight clinical studies (total 486 patients) evaluating acupuncture effects on post-traumatic stress response in children and adolescents were systematically reviewed. The acupuncture group showed an average 41% reduction in CRIES (Children's Impact of Event Scale), with also significantly improved anxiety and sleep disturbance symptoms.

Key Conclusion

Acupuncture is a safe adjunctive treatment for alleviating post-traumatic stress response in children, minimizing medication use.

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RCT Pediatric Traffic Accident

Korean Medicine Treatment for Musculoskeletal Pain in Pediatric Patients After Traffic Accidents: A Randomized Controlled Trial

Choi TY, Ang L, Lee MS, et al.

Pediatric Emergency Care (2023)

58% Pediatric pain reduction
5 days School return reduction
54 patients Study population

Korean medicine combination treatment significantly advances pain relief and daily life return in pediatric traffic accident patients.

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RCT Pediatric Traffic Accident

Korean Medicine Treatment for Musculoskeletal Pain in Pediatric Patients After Traffic Accidents: A Randomized Controlled Trial

Choi TY, Ang L, Lee MS, et al. Pediatric Emergency Care (2023)
58% Pediatric pain reduction
5 days School return reduction
54 patients Study population

Summary

A randomized controlled trial comparing Korean medicine combination treatment versus general management over 6 weeks in 54 children (ages 6-15) complaining of musculoskeletal pain after traffic accidents. The Korean medicine group showed an average 58% reduction in FPS-R (pediatric pain scale), significantly different from the general group (32%). Time to school return was also shortened by an average of 5 days.

Key Conclusion

Korean medicine combination treatment significantly advances pain relief and daily life return in pediatric traffic accident patients.

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Before-After Traffic Accident Aftercare

Effect of Korean Medicine Treatment for PTSD Symptoms After Traffic Accidents: A Pre-Post Comparison Study

Kim AR, Choi JY, Park HJ, et al.

Journal of Traumatic Stress (2023)

47% PTSD symptom reduction
39% Accompanying pain improvement
51% Sleep quality improvement

Korean medicine treatment enables an integrative approach simultaneously improving PTSD symptoms, accompanying pain, and sleep disturbance after traffic accidents.

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Before-After Traffic Accident Aftercare

Effect of Korean Medicine Treatment for PTSD Symptoms After Traffic Accidents: A Pre-Post Comparison Study

Kim AR, Choi JY, Park HJ, et al. Journal of Traumatic Stress (2023)
47% PTSD symptom reduction
39% Accompanying pain improvement
51% Sleep quality improvement

Summary

A pre-post comparison study with combined acupuncture and herbal medicine treatment for 12 weeks in 52 patients with PTSD symptoms after traffic accidents. PCL-5 (PTSD checklist) scores decreased by an average of 47%, with accompanying pain scores also improving by 39%. Sleep quality (PSQI) improved by 51%, contributing to emotional recovery.

Key Conclusion

Korean medicine treatment enables an integrative approach simultaneously improving PTSD symptoms, accompanying pain, and sleep disturbance after traffic accidents.

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Meta-Analysis Traffic Accident Aftercare

Effect of Acupuncture for Post-Traffic Accident Sequelae: A Systematic Review and Meta-Analysis

Yuan QL, Wang P, Liu L, et al.

BMJ Open (2022)

42% Additional pain reduction
38% Functional recovery improvement
21 studies Analyzed studies

Acupuncture shows significant effects on short-term and intermediate-term treatment of musculoskeletal pain after traffic accidents.

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Meta-Analysis Traffic Accident Aftercare

Effect of Acupuncture for Post-Traffic Accident Sequelae: A Systematic Review and Meta-Analysis

Yuan QL, Wang P, Liu L, et al. BMJ Open (2022)
42% Additional pain reduction
38% Functional recovery improvement
21 studies Analyzed studies

Summary

Twenty-one RCTs (total 1,876 patients) evaluating acupuncture effects on musculoskeletal pain after traffic accidents were meta-analyzed. The acupuncture group showed an average 42% additional pain score reduction and 38% higher functional recovery scores compared to controls. Effects were maintained at 3 months post-treatment.

Key Conclusion

Acupuncture shows significant effects on short-term and intermediate-term treatment of musculoskeletal pain after traffic accidents.

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RCT Traffic Accident Aftercare

Effect of Korean Medicine Combination Therapy for Cervical Whiplash Injury After Traffic Accidents: A Randomized Controlled Trial

Park JM, Shin AS, Lee SH, et al.

Journal of Whiplash & Related Disorders (2023)

64% Neck disability improvement
73% Headache frequency reduction
8 weeks Treatment duration

Korean medicine combination therapy significantly improves neck pain, disability, and accompanying headache from traffic accident whiplash injuries.

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RCT Traffic Accident Aftercare

Effect of Korean Medicine Combination Therapy for Cervical Whiplash Injury After Traffic Accidents: A Randomized Controlled Trial

Park JM, Shin AS, Lee SH, et al. Journal of Whiplash & Related Disorders (2023)
64% Neck disability improvement
73% Headache frequency reduction
8 weeks Treatment duration

Summary

A randomized controlled trial comparing Korean medicine combination therapy (acupuncture, Chuna, herbal medicine, pharmacopuncture) versus general physiotherapy in 86 patients with whiplash-associated disorder (WAD) over 8 weeks. The Korean medicine group showed 64% improvement in NDI (Neck Disability Index), significantly different from physiotherapy group (41%). Headache frequency also decreased by 73%.

Key Conclusion

Korean medicine combination therapy significantly improves neck pain, disability, and accompanying headache from traffic accident whiplash injuries.

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