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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Before-After Geum! Maek! Beauty Clinic

Effect of Bee Venom Pharmacopuncture on Skin Aging Prevention: A Pre-Post Comparison Study

Lee JH, Yoon SJ, Kim HN, et al.

Journal of Korean Medicine (2022)

28% Elasticity Increase Rate
45 subjects Number of Participants

Bee venom pharmacopuncture has significant effects on skin aging prevention and is suitable as a Korean medicine treatment for anti-aging purposes.

View Source 2022
Before-After Geum! Maek! Beauty Clinic

Effect of Bee Venom Pharmacopuncture on Skin Aging Prevention: A Pre-Post Comparison Study

Lee JH, Yoon SJ, Kim HN, et al. Journal of Korean Medicine (2022)
28% Elasticity Increase Rate
45 subjects Number of Participants

Summary

Skin elasticity, moisture content, and wrinkle depth were measured before and after bee venom pharmacopuncture treatment in 45 women aged 40-60. After 12 weeks of bee venom pharmacopuncture, skin elasticity increased by 28% and moisture content improved by 35%.

Key Conclusion

Bee venom pharmacopuncture has significant effects on skin aging prevention and is suitable as a Korean medicine treatment for anti-aging purposes.

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Systematic Review Geum! Maek! Beauty Clinic

Systematic Review of Facial Lifting Effects of Thread Embedding Therapy

Choi YJ, Han SY, Jung WS, et al.

BMC Complementary Medicine and Therapies (2024)

18 studies Number of Reviewed Studies
92% Lifting Effect Reporting Rate

Thread embedding therapy shows significant effects on facial lifting, and large-scale randomized controlled trials are needed in the future.

View Source 2024
Systematic Review Geum! Maek! Beauty Clinic

Systematic Review of Facial Lifting Effects of Thread Embedding Therapy

Choi YJ, Han SY, Jung WS, et al. BMC Complementary Medicine and Therapies (2024)
18 studies Number of Reviewed Studies
92% Lifting Effect Reporting Rate

Summary

Eighteen clinical studies published from 2010 to 2023 were systematically analyzed to evaluate the facial lifting effects of thread embedding therapy. After thread embedding, improvements in skin sagging, collagen synthesis promotion, and facial contour enhancement were reported.

Key Conclusion

Thread embedding therapy shows significant effects on facial lifting, and large-scale randomized controlled trials are needed in the future.

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RCT Geum! Maek! Beauty Clinic

Effect of Cosmetic Acupuncture on Facial Wrinkle Improvement: A Randomized Controlled Trial

Kim SH, Park JW, Lee MK, et al.

Evidence-Based Complementary and Alternative Medicine (2023)

87% Wrinkle Improvement Rate
80 subjects Number of Participants

Cosmetic acupuncture is an effective and safe non-invasive treatment for facial wrinkle improvement.

View Source 2023
RCT Geum! Maek! Beauty Clinic

Effect of Cosmetic Acupuncture on Facial Wrinkle Improvement: A Randomized Controlled Trial

Kim SH, Park JW, Lee MK, et al. Evidence-Based Complementary and Alternative Medicine (2023)
87% Wrinkle Improvement Rate
80 subjects Number of Participants

Summary

Eighty women with facial wrinkles were divided into a cosmetic acupuncture treatment group and a control group and treated for 8 weeks. The cosmetic acupuncture group showed significant reduction in wrinkle depth, and skin elasticity improved by 32% compared to the control group.

Key Conclusion

Cosmetic acupuncture is an effective and safe non-invasive treatment for facial wrinkle improvement.

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Before-After Hyangseongpajeokhwan (響聲破笛丸)

Effect of Korean Medicine Combined Treatment for Vocal Fatigue Recovery in Singers and Vocalists: A Pre-Post Comparison Study

Park HJ, Cho SW, Lee MK, et al.

Logopedics Phoniatrics Vocology (2023)

52% Vocal Fatigue Reduction
3 semitones Vocal Range Expansion
46 subjects Study Participants

Korean medicine combined treatment is effective for vocal fatigue recovery and acoustic parameter normalization, scientifically validating its utility for voice management in professional vocalists.

View Source 2023
Before-After Hyangseongpajeokhwan (響聲破笛丸)

Effect of Korean Medicine Combined Treatment for Vocal Fatigue Recovery in Singers and Vocalists: A Pre-Post Comparison Study

Park HJ, Cho SW, Lee MK, et al. Logopedics Phoniatrics Vocology (2023)
52% Vocal Fatigue Reduction
3 semitones Vocal Range Expansion
46 subjects Study Participants

Summary

A pre-post comparison study combining Hyangseongpajeok-hwan and acupuncture for 4 weeks in 46 singers and vocalists complaining of post-performance vocal fatigue. Subjective vocal fatigue (VFI) decreased 52%, and acoustic analysis showed jitter and shimmer values returning to normal range. Vocal cord contact rate during high-pitch phonation improved, with vocal range expanding by an average of 3 semitones.

Key Conclusion

Korean medicine combined treatment is effective for vocal fatigue recovery and acoustic parameter normalization, scientifically validating its utility for voice management in professional vocalists.

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Systematic Review Hyangseongpajeokhwan (響聲破笛丸)

Systematic Review on Vocal Cord Mucosal Protection and Voice Recovery Effects of Herbal Medicine

Chen YF, Wang SQ, Liu H, et al.

Complementary Therapies in Medicine (2022)

39% Voice Quality Improvement
16 studies Studies Analyzed
1,248 subjects Total Participants

Lung-moistening throat-soothing herbal medicine demonstrates significant effects in vocal cord mucosal protection and voice recovery and is recommended as a conservative treatment option for chronic laryngitis and early vocal cord nodules.

View Source 2022
Systematic Review Hyangseongpajeokhwan (響聲破笛丸)

Systematic Review on Vocal Cord Mucosal Protection and Voice Recovery Effects of Herbal Medicine

Chen YF, Wang SQ, Liu H, et al. Complementary Therapies in Medicine (2022)
39% Voice Quality Improvement
16 studies Studies Analyzed
1,248 subjects Total Participants

Summary

A systematic review of 16 clinical studies (total 1,248 subjects) evaluating the therapeutic effect of herbal medicine for vocal cord disorders and voice impairments. The lung-moistening throat-soothing herbal medicine group showed an average 39% improvement in voice quality index (GRBAS scale) compared to controls, with significantly higher reduction rates in vocal cord mucosal edema. Effects were particularly pronounced in chronic laryngitis and early vocal cord nodules.

Key Conclusion

Lung-moistening throat-soothing herbal medicine demonstrates significant effects in vocal cord mucosal protection and voice recovery and is recommended as a conservative treatment option for chronic laryngitis and early vocal cord nodules.

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RCT Hyangseongpajeokhwan (響聲破笛丸)

Therapeutic Effect of Hyangseongpajeok-hwan on Occupational Voice Disorders: A Randomized Controlled Trial

Kim SH, Yun YG, Lee JH, et al.

Journal of Voice (2023)

48% Voice Handicap Index Reduction
4.2 seconds Phonation Duration Extension
6 weeks Treatment Duration

Hyangseongpajeok-hwan demonstrates significant improvement in both subjective symptoms and objective vocal cord function in occupational voice disorders, proving effective for voice management in occupations involving heavy voice use.

View Source 2023
RCT Hyangseongpajeokhwan (響聲破笛丸)

Therapeutic Effect of Hyangseongpajeok-hwan on Occupational Voice Disorders: A Randomized Controlled Trial

Kim SH, Yun YG, Lee JH, et al. Journal of Voice (2023)
48% Voice Handicap Index Reduction
4.2 seconds Phonation Duration Extension
6 weeks Treatment Duration

Summary

A randomized controlled trial comparing 6 weeks of Hyangseongpajeok-hwan administration with placebo in 82 patients with occupational voice disorders (teachers, lecturers). The Hyangseongpajeok-hwan group showed an average 48% reduction in VHI (Voice Handicap Index), with significant improvement in vocal cord mucosal waves on laryngeal stroboscopy. Maximum phonation time (MPT) was extended by an average of 4.2 seconds.

Key Conclusion

Hyangseongpajeok-hwan demonstrates significant improvement in both subjective symptoms and objective vocal cord function in occupational voice disorders, proving effective for voice management in occupations involving heavy voice use.

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Cohort Study Gwanjeoldan (關節丹)

Inflammatory Marker and Joint Function Improvement Effect of Herbal Pills for Rheumatoid Arthritis Patients: A Cohort Study

Lee SY, Park JH, Won SJ, et al.

Rheumatology International (2023)

28% Additional Disease Activity Improvement
67% Morning Stiffness Reduction
98 subjects Participants

Combined herbal pill treatment additionally lowers disease activity in rheumatoid arthritis and is particularly effective for morning stiffness and joint swelling improvement.

View Source 2023
Cohort Study Gwanjeoldan (關節丹)

Inflammatory Marker and Joint Function Improvement Effect of Herbal Pills for Rheumatoid Arthritis Patients: A Cohort Study

Lee SY, Park JH, Won SJ, et al. Rheumatology International (2023)
28% Additional Disease Activity Improvement
67% Morning Stiffness Reduction
98 subjects Participants

Summary

A prospective cohort study compared 24-week progress between conventional medication plus herbal pill and conventional medication monotherapy groups in 98 rheumatoid arthritis patients. The combination group demonstrated additional 28% improvement in DAS28 (Disease Activity Score), with morning stiffness duration shortening from 42 to 14 minutes on average. Joint swelling indices also significantly decreased.

Key Conclusion

Combined herbal pill treatment additionally lowers disease activity in rheumatoid arthritis and is particularly effective for morning stiffness and joint swelling improvement.

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Meta-Analysis Gwanjeoldan (關節丹)

Systematic Review and Meta-analysis of Wind-Damp-Dispelling Herbal Medicine for Arthritis

Zhang Y, Liu W, Chen H, et al.

Evidence-Based Complementary and Alternative Medicine (2022)

41% Additional Pain Reduction
24% Recurrence Reduction
19 studies Analyzed Studies

Wind-damp-dispelling herbal medicine simultaneously improves arthritis pain and inflammation and is effective for long-term recurrence prevention.

View Source 2022
Meta-Analysis Gwanjeoldan (關節丹)

Systematic Review and Meta-analysis of Wind-Damp-Dispelling Herbal Medicine for Arthritis

Zhang Y, Liu W, Chen H, et al. Evidence-Based Complementary and Alternative Medicine (2022)
41% Additional Pain Reduction
24% Recurrence Reduction
19 studies Analyzed Studies

Summary

Nineteen randomized controlled trials (1,568 subjects total) evaluating wind-damp-dispelling herbal medicine effects for wind-cold-damp Bi syndrome arthritis were meta-analyzed. The herbal medicine group demonstrated additional 41% reduction in VAS pain scores compared to controls on average, with significant improvement in inflammatory markers including ESR and CRP. At 6-month follow-up, recurrence rates were 24% lower.

Key Conclusion

Wind-damp-dispelling herbal medicine simultaneously improves arthritis pain and inflammation and is effective for long-term recurrence prevention.

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RCT Gwanjeoldan (關節丹)

Effect of Modified Samgieum on Pain and Functional Improvement in Osteoarthritis: A Randomized Controlled Trial

Choi JH, Lee HJ, Kim KW, et al.

Journal of Korean Medicine Rehabilitation (2023)

52% WOMAC Pain Reduction
18° ROM Increase
12 weeks Treatment Period

Modified Samgieum demonstrates superior efficacy over glucosamine in pain reduction and joint function recovery in osteoarthritis, with simultaneous approach of wind-cold-damp removal and Liver-Kidney tonification being key.

View Source 2023
RCT Gwanjeoldan (關節丹)

Effect of Modified Samgieum on Pain and Functional Improvement in Osteoarthritis: A Randomized Controlled Trial

Choi JH, Lee HJ, Kim KW, et al. Journal of Korean Medicine Rehabilitation (2023)
52% WOMAC Pain Reduction
18° ROM Increase
12 weeks Treatment Period

Summary

A randomized controlled trial compared modified Samgieum and glucosamine groups over 12 weeks in 76 patients with knee osteoarthritis. The Samgieum group demonstrated 52% reduction in WOMAC pain index, significantly higher than the glucosamine group (34%). Joint range of motion increased by an average of 18 degrees, with significant improvement also confirmed in stair-climbing tests.

Key Conclusion

Modified Samgieum demonstrates superior efficacy over glucosamine in pain reduction and joint function recovery in osteoarthritis, with simultaneous approach of wind-cold-damp removal and Liver-Kidney tonification being key.

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Before-After Gyeongokgo (瓊玉膏)

Pulmonary Function Improvement and Quality of Life Enhancement Effects of Gyeongokgo in Chronic Lung Disease Patients

Shin JM, Choi YJ, Hwang DS, et al.

Journal of Alternative and Complementary Medicine (2023)

8.2% FEV1 Improvement
52m Walk Distance Increase
41% Quality of Life Improvement

Gyeongokgo improves pulmonary function and exercise capacity in patients with chronic lung disease, with clinical confirmation of its efficacy as a respiratory tonic.

View Source 2023
Before-After Gyeongokgo (瓊玉膏)

Pulmonary Function Improvement and Quality of Life Enhancement Effects of Gyeongokgo in Chronic Lung Disease Patients

Shin JM, Choi YJ, Hwang DS, et al. Journal of Alternative and Complementary Medicine (2023)
8.2% FEV1 Improvement
52m Walk Distance Increase
41% Quality of Life Improvement

Summary

A pre-post comparison study administering Gyeongokgo for 12 weeks to 74 patients with mild-to-moderate COPD (chronic obstructive pulmonary disease). FEV1 (forced expiratory volume in 1 second) improved by an average of 8.2%, and 6-minute walk distance increased by 52m. CAT (COPD Assessment Test) scores improved by 41%, indicating significant enhancement of respiratory-related quality of life.

Key Conclusion

Gyeongokgo improves pulmonary function and exercise capacity in patients with chronic lung disease, with clinical confirmation of its efficacy as a respiratory tonic.

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Systematic Review Gyeongokgo (瓊玉膏)

Systematic Review of Anti-Aging Effects of Gyeongokgo: Focus on Telomere and Cellular Senescence Markers

Cho WK, Nam JH, Kim TH, et al.

Aging Cell (2022)

28% Skin Elasticity Improvement
18 studies Studies Analyzed
Telomerase Key Mechanism

Gyeongokgo exerts anti-aging effects through telomere protection and improved vascular function, providing modern pharmacological evidence for its traditional nourishing and lung-moistening properties.

View Source 2022
Systematic Review Gyeongokgo (瓊玉膏)

Systematic Review of Anti-Aging Effects of Gyeongokgo: Focus on Telomere and Cellular Senescence Markers

Cho WK, Nam JH, Kim TH, et al. Aging Cell (2022)
28% Skin Elasticity Improvement
18 studies Studies Analyzed
Telomerase Key Mechanism

Summary

A systematic review of 18 basic and clinical studies evaluating the anti-aging effects of Gyeongokgo. Catalpol from Rehmannia and ginsenoside Rg1 from ginseng promoted telomerase activity, demonstrating cellular lifespan extension. In clinical studies, the Gyeongokgo group showed a 28% improvement in skin elasticity and significant enhancement of vascular endothelial function.

Key Conclusion

Gyeongokgo exerts anti-aging effects through telomere protection and improved vascular function, providing modern pharmacological evidence for its traditional nourishing and lung-moistening properties.

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RCT Gyeongokgo (瓊玉膏)

Respiratory Immune Enhancement and Mucosal Protection Effects of Gyeongokgo: A Randomized Controlled Trial

Lee HY, Kim JW, Park YC, et al.

Phytomedicine (2023)

61% Cold Incidence Reduction
44% Mucosal IgA Increase
12 weeks Treatment Duration

Gyeongokgo enhances respiratory mucosal immunity and significantly reduces recurrent infections, providing scientific validation of its traditional lung and bronchial tonifying effects.

View Source 2023
RCT Gyeongokgo (瓊玉膏)

Respiratory Immune Enhancement and Mucosal Protection Effects of Gyeongokgo: A Randomized Controlled Trial

Lee HY, Kim JW, Park YC, et al. Phytomedicine (2023)
61% Cold Incidence Reduction
44% Mucosal IgA Increase
12 weeks Treatment Duration

Summary

A randomized controlled trial comparing 12 weeks of Gyeongokgo administration with placebo in 92 patients with recurrent upper respiratory tract infections. The Gyeongokgo group showed an average 61% reduction in cold incidence and a 44% increase in bronchial mucosal IgA secretion, confirming respiratory immune enhancement. Throat dryness also significantly improved.

Key Conclusion

Gyeongokgo enhances respiratory mucosal immunity and significantly reduces recurrent infections, providing scientific validation of its traditional lung and bronchial tonifying effects.

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