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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Narrative Review ENT Disorders

Recent Trends in Korean Medicine Approach to Allergic Rhinitis: A Narrative Review

Sung WS, Im JG, Cho KH, et al.

Complementary Therapies in Medicine (2025)

85 papers Analyzed Papers
10 years Analysis Period
5 types Major Treatment Types

Korean medicine research on allergic rhinitis is growing both quantitatively and qualitatively, with expansion of evidence-based research.

View Source 2025
Narrative Review ENT Disorders

Recent Trends in Korean Medicine Approach to Allergic Rhinitis: A Narrative Review

Sung WS, Im JG, Cho KH, et al. Complementary Therapies in Medicine (2025)
85 papers Analyzed Papers
10 years Analysis Period
5 types Major Treatment Types

Summary

Treatment trends were summarized through analysis of 85 papers on Korean medicine treatment of allergic rhinitis published in the past 10 years. Various treatments including acupuncture, herbal medicine, and intranasal pharmacopuncture have been studied, with research on immunomodulatory mechanisms increasing.

Key Conclusion

Korean medicine research on allergic rhinitis is growing both quantitatively and qualitatively, with expansion of evidence-based research.

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Case Study ENT Disorders

Case Report of Hyungaeyongyo-tang Treatment for Acute Sinusitis

Oh JM, Baek SH, Kwon OS, et al.

Journal of Korean Medicine (2020)

87.5% Symptom Improvement Rate
8 cases Case Number
7 days Onset of Effect

Hyungaeyongyo-tang is a herbal prescription that can be expected to provide rapid symptom relief in early treatment of acute sinusitis.

View Source 2020
Case Study ENT Disorders

Case Report of Hyungaeyongyo-tang Treatment for Acute Sinusitis

Oh JM, Baek SH, Kwon OS, et al. Journal of Korean Medicine (2020)
87.5% Symptom Improvement Rate
8 cases Case Number
7 days Onset of Effect

Summary

Eight patients with acute sinusitis received Hyungaeyongyo-tang for 2 weeks with progress monitoring. All patients showed marked improvement in facial pain, rhinorrhea, and nasal congestion symptoms beginning on day 7 of treatment.

Key Conclusion

Hyungaeyongyo-tang is a herbal prescription that can be expected to provide rapid symptom relief in early treatment of acute sinusitis.

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Cohort Study ENT Disorders

Long-term Effect Analysis of Bojungikgi-tang in Chronic Rhinitis Patients: A Multicenter Cohort Study

Jang IS, Ryu BH, Nam DW, et al.

Journal of Ethnopharmacology (2024)

79.2% 12-Month Symptom Improvement Maintenance
240 subjects Participants
6 sites Participating Hospitals

Bojungikgi-tang is effective for long-term symptom management in chronic rhinitis patients, with sustained effects confirmed even after treatment completion.

View Source 2024
Cohort Study ENT Disorders

Long-term Effect Analysis of Bojungikgi-tang in Chronic Rhinitis Patients: A Multicenter Cohort Study

Jang IS, Ryu BH, Nam DW, et al. Journal of Ethnopharmacology (2024)
79.2% 12-Month Symptom Improvement Maintenance
240 subjects Participants
6 sites Participating Hospitals

Summary

Two hundred forty patients with chronic rhinitis at 6 Korean medicine hospitals received Bojungikgi-tang and were followed for 12 months. Symptom improvement effects persisted for more than 6 months even after treatment completion.

Key Conclusion

Bojungikgi-tang is effective for long-term symptom management in chronic rhinitis patients, with sustained effects confirmed even after treatment completion.

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Systematic Review ENT Disorders

Systematic Review of Acupuncture Effects for Postnasal Drip Syndrome

Han SY, Moon SK, Jung WS, et al.

Evidence-Based Complementary and Alternative Medicine (2022)

74.6% Symptom Improvement Rate
890 subjects Total Subjects
12 papers Analyzed Papers

Acupuncture demonstrates significant effects in symptom alleviation as a complementary treatment for postnasal drip syndrome.

View Source 2022
Systematic Review ENT Disorders

Systematic Review of Acupuncture Effects for Postnasal Drip Syndrome

Han SY, Moon SK, Jung WS, et al. Evidence-Based Complementary and Alternative Medicine (2022)
74.6% Symptom Improvement Rate
890 subjects Total Subjects
12 papers Analyzed Papers

Summary

Twelve clinical trials were systematically analyzed to evaluate acupuncture effects in patients with postnasal drip syndrome. In data from 890 patients, the acupuncture group demonstrated significantly lower postnasal drip symptom scores compared with controls.

Key Conclusion

Acupuncture demonstrates significant effects in symptom alleviation as a complementary treatment for postnasal drip syndrome.

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Cohort Study ENT Disorders

Cohort Study of Eungyo-san Combined with Gamgil-tang in Recurrent Tonsillitis Patients

Yoon SJ, Kang BM, Cho NR, et al.

BMC Complementary Medicine and Therapies (2021)

63.2% Recurrence Reduction Rate
180 subjects Participants
6 months Follow-up Period

Eungyo-san combined with Gamgil-tang is effective in preventing tonsillitis recurrence and may serve as an alternative treatment to reduce antibiotic use frequency.

View Source 2021
Cohort Study ENT Disorders

Cohort Study of Eungyo-san Combined with Gamgil-tang in Recurrent Tonsillitis Patients

Yoon SJ, Kang BM, Cho NR, et al. BMC Complementary Medicine and Therapies (2021)
63.2% Recurrence Reduction Rate
180 subjects Participants
6 months Follow-up Period

Summary

One hundred eighty patients with recurrent tonsillitis were divided into Eungyo-san plus Gamgil-tang treatment (90 patients) and conventional treatment (90 patients) groups, followed for 6 months. The herbal treatment group showed significantly fewer tonsillitis recurrences.

Key Conclusion

Eungyo-san combined with Gamgil-tang is effective in preventing tonsillitis recurrence and may serve as an alternative treatment to reduce antibiotic use frequency.

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RCT ENT Disorders

Immunomodulatory Effect of Okbyeongpung-san in Allergic Rhinitis Patients: A Randomized Double-Blind Placebo-Controlled Trial

Park MJ, Shin HK, Lim BS, et al.

Phytomedicine (2023)

78.9% TNSS Improvement Rate
128 subjects Participants
p<0.001 Statistical Significance

Okbyeongpung-san demonstrated significant effects on immunomodulation and symptom alleviation in allergic rhinitis patients.

View Source 2023
RCT ENT Disorders

Immunomodulatory Effect of Okbyeongpung-san in Allergic Rhinitis Patients: A Randomized Double-Blind Placebo-Controlled Trial

Park MJ, Shin HK, Lim BS, et al. Phytomedicine (2023)
78.9% TNSS Improvement Rate
128 subjects Participants
p<0.001 Statistical Significance

Summary

One hundred twenty-eight patients with allergic rhinitis were compared over 12 weeks between Okbyeongpung-san and placebo groups. Serum IgE and eosinophil counts decreased significantly in the treatment group, with marked improvement in Total Nasal Symptom Score (TNSS).

Key Conclusion

Okbyeongpung-san demonstrated significant effects on immunomodulation and symptom alleviation in allergic rhinitis patients.

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Before-After ENT Disorders

Pre-Post Comparison Study of Korean Medicine Combined Treatment for Pediatric Otitis Media

Lee JH, Kim YS, Hwang DS, et al.

Journal of Korean Medicine (2022)

71.1% Tympanic Membrane Improvement Rate
45 subjects Participants
12 weeks Treatment Period

Korean medicine combined treatment can reduce recurrence frequency and contribute to hearing improvement in pediatric recurrent otitis media.

View Source 2022
Before-After ENT Disorders

Pre-Post Comparison Study of Korean Medicine Combined Treatment for Pediatric Otitis Media

Lee JH, Kim YS, Hwang DS, et al. Journal of Korean Medicine (2022)
71.1% Tympanic Membrane Improvement Rate
45 subjects Participants
12 weeks Treatment Period

Summary

Forty-five pediatric patients with recurrent otitis media received combined acupuncture and herbal medicine treatment for 12 weeks. Significant improvements were observed in tympanic membrane findings and audiometric tests after treatment.

Key Conclusion

Korean medicine combined treatment can reduce recurrence frequency and contribute to hearing improvement in pediatric recurrent otitis media.

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RCT ENT Disorders

Randomized Controlled Clinical Trial of Modified Changija-san for Sinusitis Patients

Choi YJ, Seo BK, Han CH, et al.

Complementary Therapies in Medicine (2024)

76.5% Symptom Improvement Rate
96 subjects Participants
8 weeks Treatment Period

Modified Changija-san is an effective Korean medicine treatment for symptom and quality-of-life improvement in chronic sinusitis patients.

View Source 2024
RCT ENT Disorders

Randomized Controlled Clinical Trial of Modified Changija-san for Sinusitis Patients

Choi YJ, Seo BK, Han CH, et al. Complementary Therapies in Medicine (2024)
76.5% Symptom Improvement Rate
96 subjects Participants
8 weeks Treatment Period

Summary

Ninety-six patients with chronic sinusitis were compared over 8 weeks between modified Changija-san and placebo groups. Nasal endoscopic findings and SNOT-22 scores significantly improved in the treatment group. Side effects were limited to 3 cases of mild gastrointestinal disturbance.

Key Conclusion

Modified Changija-san is an effective Korean medicine treatment for symptom and quality-of-life improvement in chronic sinusitis patients.

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Meta-Analysis ENT Disorders

Systematic Review and Meta-analysis of Korean Medicine Rhinitis Treatment Focused on Socheongryong-tang

Kim SH, Park JW, Lee MK, et al.

Evidence-Based Complementary and Alternative Medicine (2023)

82.3% Symptom Improvement Rate
1420 subjects Participants
18 papers Analyzed Papers

Socheongryong-tang is effective in improving major symptoms of allergic rhinitis and can be utilized as a safe treatment with low adverse event rates.

View Source 2023
Meta-Analysis ENT Disorders

Systematic Review and Meta-analysis of Korean Medicine Rhinitis Treatment Focused on Socheongryong-tang

Kim SH, Park JW, Lee MK, et al. Evidence-Based Complementary and Alternative Medicine (2023)
82.3% Symptom Improvement Rate
1420 subjects Participants
18 papers Analyzed Papers

Summary

A systematic review including 18 RCTs was conducted to evaluate the efficacy of Socheongryong-tang for allergic rhinitis. Analysis of 1,420 patients showed significant improvements in major symptoms including nasal congestion, sneezing, and rhinorrhea in the Socheongryong-tang group.

Key Conclusion

Socheongryong-tang is effective in improving major symptoms of allergic rhinitis and can be utilized as a safe treatment with low adverse event rates.

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Before-After Digestive Disorders

Effect of Herbal Medicine on Intestinal Barrier Permeability in Patients with Digestive Disorders

Go HY, Park YC, Shin NR, et al.

Journal of Ethnopharmacology (2025)

38% Permeability Reduction
40 subjects Participants

Herbal medicine corrects increased intestinal permeability and improves the underlying pathophysiology of digestive disorders.

View Source 2025
Before-After Digestive Disorders

Effect of Herbal Medicine on Intestinal Barrier Permeability in Patients with Digestive Disorders

Go HY, Park YC, Shin NR, et al. Journal of Ethnopharmacology (2025)
38% Permeability Reduction
40 subjects Participants

Summary

Forty patients with IBS and functional dyspepsia received herbal medicine for 8 weeks, and intestinal permeability was assessed using the lactulose-mannitol test. The intestinal permeability index decreased by 38% after herbal treatment, indicating normalization of barrier function.

Key Conclusion

Herbal medicine corrects increased intestinal permeability and improves the underlying pathophysiology of digestive disorders.

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Systematic Review Digestive Disorders

Effect of Korean Medicine Treatment for Functional Abdominal Pain in Children: A Systematic Review

Choi SH, Lee JA, Kim AR, et al.

BMC Complementary Medicine and Therapies (2023)

11 studies Number of Reviewed Studies
73% Abdominal Pain Reduction Rate

Korean medicine treatment is effective for pediatric functional abdominal pain and is suitable for pediatric patients with fewer side effects.

View Source 2023
Systematic Review Digestive Disorders

Effect of Korean Medicine Treatment for Functional Abdominal Pain in Children: A Systematic Review

Choi SH, Lee JA, Kim AR, et al. BMC Complementary Medicine and Therapies (2023)
11 studies Number of Reviewed Studies
73% Abdominal Pain Reduction Rate

Summary

The effect of Korean medicine treatment (herbal medicine, acupuncture, pediatric chuna) for pediatric functional abdominal pain was systematically analyzed across 11 studies. The abdominal pain frequency reduction rate of the Korean medicine treatment group was superior to the Western medicine control group.

Key Conclusion

Korean medicine treatment is effective for pediatric functional abdominal pain and is suitable for pediatric patients with fewer side effects.

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Cross-Sectional Digestive Disorders

Drug Interaction Safety Evaluation of Herbal Medicines Used in Digestive Diseases

Ku BC, Won JH, Song MY, et al.

Phytomedicine (2022)

8 types Number of Reviewed Prescriptions
97% Safety Rate

Korean medicine digestive prescriptions have a low risk of interactions with major Western medicines and are safe for concurrent use.

View Source 2022
Cross-Sectional Digestive Disorders

Drug Interaction Safety Evaluation of Herbal Medicines Used in Digestive Diseases

Ku BC, Won JH, Song MY, et al. Phytomedicine (2022)
8 types Number of Reviewed Prescriptions
97% Safety Rate

Summary

Drug interactions of 8 herbal medicine prescriptions frequently used in digestive diseases with Western medicines were evaluated by CYP450 enzyme analysis and clinical monitoring. No clinically significant drug interactions were observed in most prescriptions.

Key Conclusion

Korean medicine digestive prescriptions have a low risk of interactions with major Western medicines and are safe for concurrent use.

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