금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

📅 Book Appointment 📋 Geummaek Herbal Medicine 💬 Reviews 📝 Health Columns
Research Papers
🔍

Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Cross-Sectional Gongjindan (拱辰丹)

Exercise Performance Enhancement Effect of Gongjindan: A Cross-Sectional Study in Elite Athletes

Bae SH, Kim WI, Choi ES, et al.

Complementary Therapies in Medicine (2023)

8.7% VO2max Improvement
75 subjects Participants
p=0.012 Endurance Significance

Regular Gongjindan administration positively influences physical fitness and exercise performance enhancement in athletes.

View Source 2023
Cross-Sectional Gongjindan (拱辰丹)

Exercise Performance Enhancement Effect of Gongjindan: A Cross-Sectional Study in Elite Athletes

Bae SH, Kim WI, Choi ES, et al. Complementary Therapies in Medicine (2023)
8.7% VO2max Improvement
75 subjects Participants
p=0.012 Endurance Significance

Summary

Physical fitness tests and exercise performance were compared between elite athletes regularly taking Gongjindan (35) and non-takers (40). VO2max, muscular endurance, and recovery rate were significantly higher in the Gongjindan group.

Key Conclusion

Regular Gongjindan administration positively influences physical fitness and exercise performance enhancement in athletes.

이 논문 정리 페이지로 이동 →
View Full Paper
Before-After Gongjindan (拱辰丹)

Effect of Gongjindan for Postpartum Physical Strength Recovery: A Pre-Post Comparison Study

Yun YJ, Lee MJ, Kang SH, et al.

Journal of Korean Medicine (2022)

73.5% Fatigue Improvement Rate
48 subjects Participants
6 weeks Treatment Period

Gongjindan is an effective tonic prescription for postpartum physical strength recovery and anemia improvement.

View Source 2022
Before-After Gongjindan (拱辰丹)

Effect of Gongjindan for Postpartum Physical Strength Recovery: A Pre-Post Comparison Study

Yun YJ, Lee MJ, Kang SH, et al. Journal of Korean Medicine (2022)
73.5% Fatigue Improvement Rate
48 subjects Participants
6 weeks Treatment Period

Summary

Forty-eight postpartum mothers complaining of fatigue and physical weakness received Gongjindan for 6 weeks. Significant improvements were observed in FSS scores and serum ferritin and hemoglobin levels.

Key Conclusion

Gongjindan is an effective tonic prescription for postpartum physical strength recovery and anemia improvement.

이 논문 정리 페이지로 이동 →
View Full Paper
RCT Gongjindan (拱辰丹)

Cognitive Function Improvement Effect of Gongjindan: Randomized Controlled Trial in Mild Cognitive Impairment Patients

Chung SY, Kim JH, Park YC, et al.

BMC Complementary Medicine and Therapies (2024)

3.2 points MMSE Score Improvement
72 subjects Participants
p=0.001 MoCA Significance

Gongjindan is effective in improving cognitive function in mild cognitive impairment patients and may contribute to dementia prevention.

View Source 2024
RCT Gongjindan (拱辰丹)

Cognitive Function Improvement Effect of Gongjindan: Randomized Controlled Trial in Mild Cognitive Impairment Patients

Chung SY, Kim JH, Park YC, et al. BMC Complementary Medicine and Therapies (2024)
3.2 points MMSE Score Improvement
72 subjects Participants
p=0.001 MoCA Significance

Summary

Seventy-two patients with mild cognitive impairment were divided into Gongjindan (36) and placebo (36) groups for 12 weeks of treatment. Significant improvements were observed in MMSE, MoCA scores, and working memory tests in the treatment group.

Key Conclusion

Gongjindan is effective in improving cognitive function in mild cognitive impairment patients and may contribute to dementia prevention.

이 논문 정리 페이지로 이동 →
View Full Paper
Case Study Gongjindan (拱辰丹)

Experimental Study on Chondrocyte Protection and Growth Factor Secretion Effects of Deer Antler

Jeong MJ, Lee GH, Bae JS, et al.

Journal of Ethnopharmacology (2019)

38.4% Cell Survival Increase
IGF-1 Major Growth Factor
in vitro Study Type

Deer antler protects chondrocytes and promotes growth factor secretion, contributing to joint and tissue regeneration.

View Source 2019
Case Study Gongjindan (拱辰丹)

Experimental Study on Chondrocyte Protection and Growth Factor Secretion Effects of Deer Antler

Jeong MJ, Lee GH, Bae JS, et al. Journal of Ethnopharmacology (2019)
38.4% Cell Survival Increase
IGF-1 Major Growth Factor
in vitro Study Type

Summary

The effect of deer antler extract on chondrocyte survival, proliferation, and growth factor (IGF-1, TGF-β) secretion was evaluated in vitro. Chondrocyte survival increased dose-dependently, with IGF-1 secretion promoted.

Key Conclusion

Deer antler protects chondrocytes and promotes growth factor secretion, contributing to joint and tissue regeneration.

이 논문 정리 페이지로 이동 →
View Full Paper
Before-After Gongjindan (拱辰丹)

Heart Rate Variability Analysis of Autonomic Function Changes Following Gongjindan Administration

Son JY, Hong SH, Kim CH, et al.

Phytomedicine (2022)

27.8% SDNN Increase Rate
64 subjects Participants
4 weeks Treatment Period

Gongjindan is effective in restoring autonomic balance and contributes to alleviation of stress-related symptoms.

View Source 2022
Before-After Gongjindan (拱辰丹)

Heart Rate Variability Analysis of Autonomic Function Changes Following Gongjindan Administration

Son JY, Hong SH, Kim CH, et al. Phytomedicine (2022)
27.8% SDNN Increase Rate
64 subjects Participants
4 weeks Treatment Period

Summary

Sixty-four patients with stress-induced autonomic imbalance received Gongjindan for 4 weeks, with heart rate variability (HRV) analyzed. Parasympathetic indicators including SDNN, RMSSD, and HF significantly increased.

Key Conclusion

Gongjindan is effective in restoring autonomic balance and contributes to alleviation of stress-related symptoms.

이 논문 정리 페이지로 이동 →
View Full Paper
Before-After ENT Disorders

Antimicrobial and Anti-biofilm Activity Study of Changija-san in Chronic Sinusitis

Eom TK, Jung HJ, Kim MR, et al.

Journal of Ethnopharmacology (2023)

74.2% Biofilm Inhibition Rate
36 subjects Clinical Participants
83.3% Bacterial Conversion Rate

Changija-san possesses antimicrobial and anti-biofilm activity against chronic sinusitis pathogens and is also clinically useful.

View Source 2023
Before-After ENT Disorders

Antimicrobial and Anti-biofilm Activity Study of Changija-san in Chronic Sinusitis

Eom TK, Jung HJ, Kim MR, et al. Journal of Ethnopharmacology (2023)
74.2% Biofilm Inhibition Rate
36 subjects Clinical Participants
83.3% Bacterial Conversion Rate

Summary

Antimicrobial and anti-biofilm activity of Changija-san extract against chronic sinusitis pathogens (S. aureus, P. aeruginosa) was evaluated through in vitro experiments. Changija-san demonstrated significant biofilm inhibition effects against both bacterial species. In 36 clinical patients, bacterial culture conversion rates were also high.

Key Conclusion

Changija-san possesses antimicrobial and anti-biofilm activity against chronic sinusitis pathogens and is also clinically useful.

이 논문 정리 페이지로 이동 →
View Full Paper
Cross-Sectional ENT Disorders

Survey Study on Patient Satisfaction and Treatment Adherence in Korean Medicine Treatment for Rhinitis

Moon HW, Jang SB, Kwak MA, et al.

Journal of Korean Medicine (2024)

4.2/5 Patient Satisfaction
89.4% Treatment Adherence
320 subjects Participants

High patient satisfaction and adherence to Korean medicine treatment for rhinitis suggest that Korean medicine is a suitable approach for rhinitis management.

View Source 2024
Cross-Sectional ENT Disorders

Survey Study on Patient Satisfaction and Treatment Adherence in Korean Medicine Treatment for Rhinitis

Moon HW, Jang SB, Kwak MA, et al. Journal of Korean Medicine (2024)
4.2/5 Patient Satisfaction
89.4% Treatment Adherence
320 subjects Participants

Summary

Three hundred twenty patients receiving Korean medicine treatment for rhinitis were surveyed on satisfaction and treatment adherence. Overall satisfaction was 4.2/5, and treatment adherence reached a high level of 89.4%.

Key Conclusion

High patient satisfaction and adherence to Korean medicine treatment for rhinitis suggest that Korean medicine is a suitable approach for rhinitis management.

이 논문 정리 페이지로 이동 →
View Full Paper
RCT ENT Disorders

Randomized Controlled Trial of Combined Extracorporeal Shock Wave Acupuncture and Herbal Medicine for Allergic Rhinitis Patients

Ryu JK, Shin BC, Lee MS, et al.

Evidence-Based Complementary and Alternative Medicine (2021)

85.1% Combination Group Improvement Rate
94 subjects Participants
8 weeks Treatment Period

Combined extracorporeal shock wave acupuncture and herbal medicine enhances therapeutic efficacy in allergic rhinitis treatment.

View Source 2021
RCT ENT Disorders

Randomized Controlled Trial of Combined Extracorporeal Shock Wave Acupuncture and Herbal Medicine for Allergic Rhinitis Patients

Ryu JK, Shin BC, Lee MS, et al. Evidence-Based Complementary and Alternative Medicine (2021)
85.1% Combination Group Improvement Rate
94 subjects Participants
8 weeks Treatment Period

Summary

Ninety-four patients with allergic rhinitis were assigned to extracorporeal shock wave acupuncture plus herbal medicine (47) or herbal medicine monotherapy (47) groups for 8 weeks. The combination group demonstrated significantly greater improvements in RQLQ scores and nasal endoscopic findings.

Key Conclusion

Combined extracorporeal shock wave acupuncture and herbal medicine enhances therapeutic efficacy in allergic rhinitis treatment.

이 논문 정리 페이지로 이동 →
View Full Paper
Cross-Sectional ENT Disorders

Economic Analysis of Korean Medicine Treatment for ENT Diseases: Based on National Health Insurance Big Data

Jo JY, Hwang EH, Son CG, et al.

BMC Complementary Medicine and Therapies (2025)

23.7% Cost Reduction Rate
15,842 subjects Analyzed
6 years Analysis Period

In ENT diseases, Korean medicine treatment is cost-effective and may contribute to reduced healthcare utilization.

View Source 2025
Cross-Sectional ENT Disorders

Economic Analysis of Korean Medicine Treatment for ENT Diseases: Based on National Health Insurance Big Data

Jo JY, Hwang EH, Son CG, et al. BMC Complementary Medicine and Therapies (2025)
23.7% Cost Reduction Rate
15,842 subjects Analyzed
6 years Analysis Period

Summary

Health insurance claims data from 2018-2023 were used to compare medical costs and reuse rates between Korean medicine and conventional medicine treatment for ENT diseases. The Korean medicine group demonstrated lower annual total medical costs and fewer revisits.

Key Conclusion

In ENT diseases, Korean medicine treatment is cost-effective and may contribute to reduced healthcare utilization.

이 논문 정리 페이지로 이동 →
View Full Paper
Before-After ENT Disorders

Analysis of Quality-of-Life Changes Before and After Herbal Medicine Treatment in Postnasal Drip Syndrome Patients

Chae BY, Lim SC, Yoon HJ, et al.

Complementary Therapies in Medicine (2019)

67.3% SNOT-22 Improvement Rate
52 subjects Participants
p<0.001 SF-36 Improvement Significance

Herbal medicine treatment contributes not only to symptom improvement but also to overall quality-of-life enhancement in postnasal drip syndrome patients.

View Source 2019
Before-After ENT Disorders

Analysis of Quality-of-Life Changes Before and After Herbal Medicine Treatment in Postnasal Drip Syndrome Patients

Chae BY, Lim SC, Yoon HJ, et al. Complementary Therapies in Medicine (2019)
67.3% SNOT-22 Improvement Rate
52 subjects Participants
p<0.001 SF-36 Improvement Significance

Summary

Fifty-two patients with postnasal drip syndrome received herbal medicine treatment for 8 weeks, with quality-of-life changes evaluated via SNOT-22 and SF-36 questionnaires. Significant improvements were confirmed in both questionnaires.

Key Conclusion

Herbal medicine treatment contributes not only to symptom improvement but also to overall quality-of-life enhancement in postnasal drip syndrome patients.

이 논문 정리 페이지로 이동 →
View Full Paper
Systematic Review ENT Disorders

Combined Effect of Nasal Irrigation and Herbal Medicine for Rhinitis Treatment: A Systematic Review

Noh JH, Kim KS, Won JY, et al.

Phytomedicine (2022)

88.1% Combination Group Efficacy
10 papers Analyzed Papers
OR 2.34 Effect Size

Combination of nasal irrigation and herbal medicine demonstrates synergistic effects in rhinitis treatment.

View Source 2022
Systematic Review ENT Disorders

Combined Effect of Nasal Irrigation and Herbal Medicine for Rhinitis Treatment: A Systematic Review

Noh JH, Kim KS, Won JY, et al. Phytomedicine (2022)
88.1% Combination Group Efficacy
10 papers Analyzed Papers
OR 2.34 Effect Size

Summary

Ten RCTs were analyzed to evaluate the combined effect of nasal irrigation and herbal medicine for rhinitis treatment. The combination group demonstrated superior symptom improvement compared with herbal medicine alone or nasal irrigation alone.

Key Conclusion

Combination of nasal irrigation and herbal medicine demonstrates synergistic effects in rhinitis treatment.

이 논문 정리 페이지로 이동 →
View Full Paper
Case Study ENT Disorders

Antipyretic and Anti-inflammatory Effect of Eungyo-san for Acute Tonsillitis: A Case Report

Go HY, Kim SJ, Baik TH, et al.

Journal of Korean Medicine (2023)

70% Pharyngeal Pain Reduction
15 subjects Participants
48 hours Time to Defervescence

Eungyo-san is an effective herbal prescription for rapid symptom relief in acute tonsillitis.

View Source 2023
Case Study ENT Disorders

Antipyretic and Anti-inflammatory Effect of Eungyo-san for Acute Tonsillitis: A Case Report

Go HY, Kim SJ, Baik TH, et al. Journal of Korean Medicine (2023)
70% Pharyngeal Pain Reduction
15 subjects Participants
48 hours Time to Defervescence

Summary

Fifteen adult patients visiting clinic for acute tonsillitis received Eungyo-san with progress monitoring for 7 days. Fever resolved within 48 hours of administration, and pharyngeal pain VAS scores decreased by an average of 70%.

Key Conclusion

Eungyo-san is an effective herbal prescription for rapid symptom relief in acute tonsillitis.

이 논문 정리 페이지로 이동 →
View Full Paper