금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

📅 Book Appointment 📋 Geummaek Herbal Medicine 💬 Reviews 📝 Health Columns
Research Papers
🔍

Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Cross-Sectional Geum! Maek! Capsule Diet

Korean Medicine Treatment Satisfaction and Quality of Life Changes in Obese Patients: A Multicenter Cross-Sectional Study

Ha NY, Shin JY, Choi WJ, et al.

Journal of Korean Medicine (2019)

4.1/5 Treatment Satisfaction
350 subjects Number of Participants

Korean medicine obesity treatment contributes to high patient satisfaction along with quality of life improvement.

View Source 2019
Cross-Sectional Geum! Maek! Capsule Diet

Korean Medicine Treatment Satisfaction and Quality of Life Changes in Obese Patients: A Multicenter Cross-Sectional Study

Ha NY, Shin JY, Choi WJ, et al. Journal of Korean Medicine (2019)
4.1/5 Treatment Satisfaction
350 subjects Number of Participants

Summary

Treatment satisfaction and SF-36 quality of life scores were analyzed in 350 patients receiving Korean medicine obesity treatment at 8 Korean medicine clinics. Overall satisfaction was 4.1/5 points, with significant improvements in physical function and mental health domains.

Key Conclusion

Korean medicine obesity treatment contributes to high patient satisfaction along with quality of life improvement.

View Full Paper
Case Study Geum! Maek! Capsule Diet

Adipocyte Differentiation Inhibition Mechanism of Herbal Medicine Extract: An in vitro Study

Roh SS, Jung AY, Kwon DY, et al.

Journal of Ethnopharmacology (2021)

68% Differentiation Inhibition Rate
3 types Major Herbal Materials

Herbal medicine extracts effectively block adipocyte differentiation through inhibition of key transcription factors.

View Source 2021
Case Study Geum! Maek! Capsule Diet

Adipocyte Differentiation Inhibition Mechanism of Herbal Medicine Extract: An in vitro Study

Roh SS, Jung AY, Kwon DY, et al. Journal of Ethnopharmacology (2021)
68% Differentiation Inhibition Rate
3 types Major Herbal Materials

Summary

The 3T3-L1 preadipocyte differentiation inhibition effect of a combined herbal medicine extract (Astragalus, Atractylodes, Alisma) was evaluated. The herbal medicine extract inhibited adipocyte differentiation by 68% by suppressing PPARγ and C/EBPα expression.

Key Conclusion

Herbal medicine extracts effectively block adipocyte differentiation through inhibition of key transcription factors.

View Full Paper
Systematic Review Geum! Maek! Capsule Diet

Systematic Review of Korean Medicine Diet Effects on Cardiovascular Risk Factors

Oh HW, Sung AD, Min SY, et al.

Evidence-Based Complementary and Alternative Medicine (2025)

19 studies Number of Reviewed Studies
4 Improved Risk Factors

Korean medicine diet comprehensively reduces cardiovascular risk beyond weight loss.

View Source 2025
Systematic Review Geum! Maek! Capsule Diet

Systematic Review of Korean Medicine Diet Effects on Cardiovascular Risk Factors

Oh HW, Sung AD, Min SY, et al. Evidence-Based Complementary and Alternative Medicine (2025)
19 studies Number of Reviewed Studies
4 Improved Risk Factors

Summary

The effect of Korean medicine diet on cardiovascular risk factors (blood pressure, blood glucose, lipids, waist circumference) was systematically analyzed across 19 studies. Significant improvements were confirmed in all 4 risk factors in the Korean medicine treatment group.

Key Conclusion

Korean medicine diet comprehensively reduces cardiovascular risk beyond weight loss.

View Full Paper
RCT Digestive Disorders

Effect of Acupuncture on Functional Dyspepsia: A Randomized Controlled Trial

Kim JH, Lee TY, Park YC, et al.

Evidence-Based Complementary and Alternative Medicine (2023)

52% Symptom Improvement Rate
90 subjects Number of Participants

Acupuncture is effective for symptom improvement in functional dyspepsia and shows significant superiority compared to sham treatment.

View Source 2023
RCT Digestive Disorders

Effect of Acupuncture on Functional Dyspepsia: A Randomized Controlled Trial

Kim JH, Lee TY, Park YC, et al. Evidence-Based Complementary and Alternative Medicine (2023)
52% Symptom Improvement Rate
90 subjects Number of Participants

Summary

Ninety patients with functional dyspepsia (Rome IV criteria) were divided into an acupuncture treatment group and a sham acupuncture group and treated for 8 weeks. The acupuncture treatment group showed a 52% improvement in dyspepsia symptom scores (NDI), demonstrating a significant difference from the sham group (21%).

Key Conclusion

Acupuncture is effective for symptom improvement in functional dyspepsia and shows significant superiority compared to sham treatment.

View Full Paper
Meta-Analysis Digestive Disorders

Systematic Review and Meta-Analysis of Herbal Medicine Treatment for Irritable Bowel Syndrome

Choi JY, Ko SJ, Park JW, et al.

BMC Complementary Medicine and Therapies (2024)

OR 2.56 Odds Ratio
21 studies Number of Reviewed RCTs

Herbal medicine demonstrates significant effects compared to Western medicine for IBS symptom improvement, with particularly pronounced effects in diarrhea-predominant and mixed types.

View Source 2024
Meta-Analysis Digestive Disorders

Systematic Review and Meta-Analysis of Herbal Medicine Treatment for Irritable Bowel Syndrome

Choi JY, Ko SJ, Park JW, et al. BMC Complementary Medicine and Therapies (2024)
OR 2.56 Odds Ratio
21 studies Number of Reviewed RCTs

Summary

The effect of herbal medicine treatment for irritable bowel syndrome (IBS) was meta-analyzed across 21 RCTs. The overall symptom improvement rate of the herbal medicine group was significantly higher than the Western medicine control group at OR 2.56 (95% CI: 1.87-3.51).

Key Conclusion

Herbal medicine demonstrates significant effects compared to Western medicine for IBS symptom improvement, with particularly pronounced effects in diarrhea-predominant and mixed types.

View Full Paper
RCT Digestive Disorders

Treatment Effect of Banhasasim-tang for Reflux Esophagitis: A Randomized Controlled Trial

Lee SJ, Kim NK, Baek NI, et al.

Journal of Ethnopharmacology (2022)

79% Symptom Improvement Rate
70 subjects Number of Participants

Banhasasim-tang demonstrates effects similar to PPIs in mild-to-moderate reflux esophagitis and may serve as a safe alternative.

View Source 2022
RCT Digestive Disorders

Treatment Effect of Banhasasim-tang for Reflux Esophagitis: A Randomized Controlled Trial

Lee SJ, Kim NK, Baek NI, et al. Journal of Ethnopharmacology (2022)
79% Symptom Improvement Rate
70 subjects Number of Participants

Summary

Seventy patients with reflux esophagitis (LA classification grades A-B) were divided into a Banhasasim-tang group and a PPI control group and treated for 8 weeks. The symptom improvement rate of the Banhasasim-tang group (79%) showed no statistically significant difference from the PPI group (83%).

Key Conclusion

Banhasasim-tang demonstrates effects similar to PPIs in mild-to-moderate reflux esophagitis and may serve as a safe alternative.

View Full Paper
Before-After Digestive Disorders

Gastrointestinal Motility Promotion Effect of Moxibustion for Digestive Diseases

Shin JC, Hwang MS, Park SU, et al.

Complementary Therapies in Medicine (2023)

28% Gastric Emptying Improvement Rate
45 subjects Number of Participants

Moxibustion promotes gastrointestinal motility and contributes to functional dyspepsia improvement.

View Source 2023
Before-After Digestive Disorders

Gastrointestinal Motility Promotion Effect of Moxibustion for Digestive Diseases

Shin JC, Hwang MS, Park SU, et al. Complementary Therapies in Medicine (2023)
28% Gastric Emptying Improvement Rate
45 subjects Number of Participants

Summary

Gastric emptying time before and after moxibustion treatment at Zusanli (ST36) was measured by ultrasound in 45 patients with functional dyspepsia. After moxibustion treatment, gastric half-emptying time was shortened by an average of 28%.

Key Conclusion

Moxibustion promotes gastrointestinal motility and contributes to functional dyspepsia improvement.

View Full Paper
RCT Digestive Disorders

Treatment Effect of Sogeonjung-tang for Chronic Gastritis and Gastric Mucosal Protection Mechanism

Park JM, Han YM, Oh JY, et al.

Phytomedicine (2021)

67% Inflammation Improvement Rate
55 subjects Number of Participants

Sogeonjung-tang is effective for chronic gastritis treatment through gastric mucosal protection mechanisms.

View Source 2021
RCT Digestive Disorders

Treatment Effect of Sogeonjung-tang for Chronic Gastritis and Gastric Mucosal Protection Mechanism

Park JM, Han YM, Oh JY, et al. Phytomedicine (2021)
67% Inflammation Improvement Rate
55 subjects Number of Participants

Summary

Sogeonjung-tang was administered for 12 weeks to 55 patients with chronic gastritis, and endoscopic findings and H. pylori status were evaluated. Gastric mucosal inflammation grade improved by 67%, and gastric mucosal defense factor (PGE2) secretion increased.

Key Conclusion

Sogeonjung-tang is effective for chronic gastritis treatment through gastric mucosal protection mechanisms.

View Full Paper
Cohort Study Digestive Disorders

Combined Acupuncture and Herbal Medicine Treatment and Quality of Life Changes in IBS Patients: A Cohort Study

Song MY, Cho SH, Kim JA, et al.

Journal of Korean Medicine (2024)

41 points IBS-QOL Improvement
80 subjects Number of Participants

Combined acupuncture and herbal medicine treatment more effectively improves quality of life in IBS patients than monotherapy.

View Source 2024
Cohort Study Digestive Disorders

Combined Acupuncture and Herbal Medicine Treatment and Quality of Life Changes in IBS Patients: A Cohort Study

Song MY, Cho SH, Kim JA, et al. Journal of Korean Medicine (2024)
41 points IBS-QOL Improvement
80 subjects Number of Participants

Summary

Eighty IBS patients were divided into an acupuncture monotherapy group, a herbal medicine monotherapy group, and an acupuncture-herbal medicine combined group, and followed for 12 weeks. The combined group showed a 41-point improvement in IBS-QOL scores, significantly higher than the monotherapy groups (acupuncture 28 points, herbal medicine 31 points).

Key Conclusion

Combined acupuncture and herbal medicine treatment more effectively improves quality of life in IBS patients than monotherapy.

View Full Paper
Systematic Review Digestive Disorders

GERD Recurrence Prevention Effect of Korean Medicine Treatment: A Systematic Review

Yoo HJ, Lee SG, Kim HY, et al.

BMC Complementary Medicine and Therapies (2022)

18% Recurrence Rate
16 studies Number of Reviewed Studies

Korean medicine treatment is effective for GERD recurrence prevention and may serve as an alternative to long-term PPI use.

View Source 2022
Systematic Review Digestive Disorders

GERD Recurrence Prevention Effect of Korean Medicine Treatment: A Systematic Review

Yoo HJ, Lee SG, Kim HY, et al. BMC Complementary Medicine and Therapies (2022)
18% Recurrence Rate
16 studies Number of Reviewed Studies

Summary

The effect of Korean medicine treatment for preventing recurrence of gastroesophageal reflux disease (GERD) was systematically analyzed across 16 studies. The 6-month recurrence rate of the herbal medicine maintenance treatment group was 18%, significantly lower than the PPI discontinuation group (42%).

Key Conclusion

Korean medicine treatment is effective for GERD recurrence prevention and may serve as an alternative to long-term PPI use.

View Full Paper
Before-After Digestive Disorders

Effect of Electroacupuncture on Gastric Accommodation in Functional Dyspepsia Patients

Jung HK, Choi MG, Lim CH, et al.

Evidence-Based Complementary and Alternative Medicine (2023)

23% Accommodation Volume Increase
40 subjects Number of Participants

Electroacupuncture corrects the core pathophysiology of functional dyspepsia by improving gastric accommodation.

View Source 2023
Before-After Digestive Disorders

Effect of Electroacupuncture on Gastric Accommodation in Functional Dyspepsia Patients

Jung HK, Choi MG, Lim CH, et al. Evidence-Based Complementary and Alternative Medicine (2023)
23% Accommodation Volume Increase
40 subjects Number of Participants

Summary

Gastric accommodation before and after electroacupuncture treatment was measured by barostat in 40 patients with functional dyspepsia. After electroacupuncture, gastric accommodation volume increased by an average of 23%, with improvement in postprandial discomfort.

Key Conclusion

Electroacupuncture corrects the core pathophysiology of functional dyspepsia by improving gastric accommodation.

View Full Paper
Meta-Analysis Digestive Disorders

Meta-Analysis of Treatment Effect of Sagunja-tang Modifications for Functional Dyspepsia

Kwon SJ, Bae KH, Lee BH, et al.

Complementary Therapies in Medicine (2024)

RR 1.38 Relative Risk
14 studies Number of Reviewed RCTs

Sagunja-tang modifications demonstrate significant effects for functional dyspepsia treatment with a moderate level of evidence.

View Source 2024
Meta-Analysis Digestive Disorders

Meta-Analysis of Treatment Effect of Sagunja-tang Modifications for Functional Dyspepsia

Kwon SJ, Bae KH, Lee BH, et al. Complementary Therapies in Medicine (2024)
RR 1.38 Relative Risk
14 studies Number of Reviewed RCTs

Summary

The functional dyspepsia treatment effect of Sagunja-tang and modifications was meta-analyzed across 14 RCTs. The symptom improvement rate of the Sagunja-tang group was significantly higher than the control group at RR 1.38 (95% CI: 1.21-1.58).

Key Conclusion

Sagunja-tang modifications demonstrate significant effects for functional dyspepsia treatment with a moderate level of evidence.

View Full Paper