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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Cohort Study Wellness / Restoration

Effect of Adjunctive Herbal Treatment for Hypothyroidism: A Prospective Cohort Study

Lim EM, Kim YK, Jung WS, et al.

Thyroid (2025)

75 subjects Participants
Residual symptoms 48% improvement Symptom Relief
TPO-Ab reduction Autoimmune Stabilization

Personalized herbal medicine can be utilized as adjunctive therapy for managing residual symptoms in hypothyroid patients on levothyroxine treatment.

View Source 2025
Cohort Study Wellness / Restoration

Effect of Adjunctive Herbal Treatment for Hypothyroidism: A Prospective Cohort Study

Lim EM, Kim YK, Jung WS, et al. Thyroid (2025)
75 subjects Participants
Residual symptoms 48% improvement Symptom Relief
TPO-Ab reduction Autoimmune Stabilization

Summary

Seventy-five hypothyroid patients with residual symptoms such as fatigue, weight gain, and constipation received personalized herbal medicine in combination with levothyroxine. Residual symptoms significantly improved and thyroid autoantibody levels stabilized.

Key Conclusion

Personalized herbal medicine can be utilized as adjunctive therapy for managing residual symptoms in hypothyroid patients on levothyroxine treatment.

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Case Study Digestive Disorders

Effect of Personalized Herbal Medicine on Metabolic Syndrome in Taeeumin Constitution: A Case Report Series

Lee KS, Jung DY, Park EK, et al.

Journal of Alternative and Complementary Medicine (2022)

10 cases Number of Cases
Triglycerides 27% reduction Lipid Improvement
Waist circumference 4.3cm reduction Abdominal Obesity Improvement

Taeeumin-tailored herbal medicine showed pronounced effects particularly in improving triglycerides and waist circumference among metabolic syndrome components.

View Source 2022
Case Study Digestive Disorders

Effect of Personalized Herbal Medicine on Metabolic Syndrome in Taeeumin Constitution: A Case Report Series

Lee KS, Jung DY, Park EK, et al. Journal of Alternative and Complementary Medicine (2022)
10 cases Number of Cases
Triglycerides 27% reduction Lipid Improvement
Waist circumference 4.3cm reduction Abdominal Obesity Improvement

Summary

Ten patients with metabolic syndrome diagnosed as Taeeumin constitution received constitution-tailored herbal medicine for 16 weeks, and changes in metabolic syndrome components (blood pressure, blood glucose, triglycerides, HDL, waist circumference) were observed.

Key Conclusion

Taeeumin-tailored herbal medicine showed pronounced effects particularly in improving triglycerides and waist circumference among metabolic syndrome components.

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Narrative Review Mental Health

Narrative Review on the Use of Herbal Prescriptions in Mental Health: Focus on Depression and Anxiety Disorders

Park YJ, Chung SY, Kim JW, et al.

Journal of Affective Disorders (2024)

35 sources Analyzed Literature
3 major prescriptions Frequently Used
Mild-moderate efficacy Effect Level

Herbal prescriptions are accumulating evidence as complementary treatment for mild-to-moderate depression and anxiety disorders, with standardization research needed.

View Source 2024
Narrative Review Mental Health

Narrative Review on the Use of Herbal Prescriptions in Mental Health: Focus on Depression and Anxiety Disorders

Park YJ, Chung SY, Kim JW, et al. Journal of Affective Disorders (2024)
35 sources Analyzed Literature
3 major prescriptions Frequently Used
Mild-moderate efficacy Effect Level

Summary

A narrative review of 35 clinical studies addressing the therapeutic effects of herbal prescriptions for depression and anxiety disorders. Prescriptions including Guibi-tang, Soyo-san, and Banhahubak-tang were most frequently studied.

Key Conclusion

Herbal prescriptions are accumulating evidence as complementary treatment for mild-to-moderate depression and anxiety disorders, with standardization research needed.

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RCT Gwanjeoldan (關節丹)

Effect of Personalized Herbal Prescriptions on Joint Symptoms and Inflammation Markers in Rheumatoid Arthritis Patients

Yoo DH, Kim HA, Song YW, et al.

Clinical Rheumatology (2023)

85 subjects Participants
DAS28 1.2 points reduction Disease Activity Improvement
Morning stiffness 42% shortening Symptom Relief

Personalized herbal medicine improves joint symptoms and inflammatory markers as a safe complementary therapy to existing rheumatoid arthritis treatment.

View Source 2023
RCT Gwanjeoldan (關節丹)

Effect of Personalized Herbal Prescriptions on Joint Symptoms and Inflammation Markers in Rheumatoid Arthritis Patients

Yoo DH, Kim HA, Song YW, et al. Clinical Rheumatology (2023)
85 subjects Participants
DAS28 1.2 points reduction Disease Activity Improvement
Morning stiffness 42% shortening Symptom Relief

Summary

Eighty-five patients with rheumatoid arthritis received personalized herbal medicine added to existing DMARDs and were observed for 24 weeks. DAS28-CRP scores significantly decreased and morning stiffness duration reduced.

Key Conclusion

Personalized herbal medicine improves joint symptoms and inflammatory markers as a safe complementary therapy to existing rheumatoid arthritis treatment.

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Cross-Sectional Wellness / Restoration

Cross-Sectional Survey on Incidence of Gastrointestinal Adverse Events and Risk Factors After Herbal Prescription

Sung SH, Han GJ, Kim JH, et al.

BMC Complementary Medicine and Therapies (2023)

3,200 subjects Surveyed
8.7% Adverse Event Incidence
Mild severity Adverse Event Severity

Most gastrointestinal adverse events of herbal prescriptions are mild, and advanced age and pre-existing digestive disorders were identified as risk factors.

View Source 2023
Cross-Sectional Wellness / Restoration

Cross-Sectional Survey on Incidence of Gastrointestinal Adverse Events and Risk Factors After Herbal Prescription

Sung SH, Han GJ, Kim JH, et al. BMC Complementary Medicine and Therapies (2023)
3,200 subjects Surveyed
8.7% Adverse Event Incidence
Mild severity Adverse Event Severity

Summary

Three thousand two hundred patients receiving herbal prescriptions were surveyed on gastrointestinal adverse event incidence and related risk factors. The overall adverse event incidence was 8.7%, with most being mild digestive disturbances.

Key Conclusion

Most gastrointestinal adverse events of herbal prescriptions are mild, and advanced age and pre-existing digestive disorders were identified as risk factors.

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Narrative Review Wellness / Restoration

Review of Temporal Changes in Herbal Prescription Patterns and Development of Evidence-Based Korean Medicine

Chae H, Lee SJ, Shin MK, et al.

Integrative Medicine Research (2022)

428 papers Papers Analyzed
32 years Analysis Period
3-fold increase in personalized research Major Trend

Herbal prescription research is evolving toward personalization and evidence-based approaches, with this trend contributing to clinical efficacy improvement.

View Source 2022
Narrative Review Wellness / Restoration

Review of Temporal Changes in Herbal Prescription Patterns and Development of Evidence-Based Korean Medicine

Chae H, Lee SJ, Shin MK, et al. Integrative Medicine Research (2022)
428 papers Papers Analyzed
32 years Analysis Period
3-fold increase in personalized research Major Trend

Summary

Changes in prescription patterns of herbal medicine clinical research published from 1990 to 2022 were analyzed, and the development direction of evidence-based Korean medicine was reviewed. A clear shift from single-prescription research to personalized prescription research was observed.

Key Conclusion

Herbal prescription research is evolving toward personalization and evidence-based approaches, with this trend contributing to clinical efficacy improvement.

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Systematic Review Lower Back Pain

Effect of Combined Personalized Herbal Medicine and Chuna Treatment for Chronic Low Back Pain: A Systematic Review

Hwang EH, Choi TY, Lee MS, et al.

Spine (2025)

16 studies Included Studies
1,234 subjects Total Participants
VAS -2.4 points Pain Improvement Difference

Combined personalized herbal medicine and chuna show superior pain and functional improvement effects compared to single treatment for chronic low back pain.

View Source 2025
Systematic Review Lower Back Pain

Effect of Combined Personalized Herbal Medicine and Chuna Treatment for Chronic Low Back Pain: A Systematic Review

Hwang EH, Choi TY, Lee MS, et al. Spine (2025)
16 studies Included Studies
1,234 subjects Total Participants
VAS -2.4 points Pain Improvement Difference

Summary

A systematic analysis of 16 randomized controlled trials investigating the combined effect of herbal medicine and chuna for chronic low back pain. The combined treatment group showed significantly greater improvement in VAS pain scores and ODI functional disability scores than single-treatment groups.

Key Conclusion

Combined personalized herbal medicine and chuna show superior pain and functional improvement effects compared to single treatment for chronic low back pain.

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RCT Private Inpatient Room

Effect of Korean Medicine Hospital Inpatient Treatment on Functional Recovery in Post-Stroke Rehabilitation Patients: A Multicenter Randomized Controlled Trial

Kim YS, Lim SM, Park SW, et al.

Stroke (2023)

160 subjects Participants
mRS 1.4 points improvement Functional Recovery
8 weeks Hospitalization Period

Korean medicine hospital intensive inpatient treatment significantly enhances the speed of functional recovery in post-stroke rehabilitation.

View Source 2023
RCT Private Inpatient Room

Effect of Korean Medicine Hospital Inpatient Treatment on Functional Recovery in Post-Stroke Rehabilitation Patients: A Multicenter Randomized Controlled Trial

Kim YS, Lim SM, Park SW, et al. Stroke (2023)
160 subjects Participants
mRS 1.4 points improvement Functional Recovery
8 weeks Hospitalization Period

Summary

One hundred sixty post-stroke rehabilitation patients were divided into a Korean medicine hospital intensive inpatient treatment group and a standard rehabilitation treatment group and compared for 8 weeks. The Korean medicine intensive inpatient treatment group showed significant improvements in Modified Rankin Scale and Barthel Index.

Key Conclusion

Korean medicine hospital intensive inpatient treatment significantly enhances the speed of functional recovery in post-stroke rehabilitation.

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Cross-Sectional Private Inpatient Room

Effect of Single-Room Korean Medicine Inpatient Treatment Environment on Patient Satisfaction and Treatment Compliance

Cho YK, Lee HJ, Park JM, et al.

Patient Preference and Adherence (2024)

250 subjects Participants
Satisfaction 92.3% Single Room Satisfaction
Compliance 18% improvement Treatment Compliance Improvement

The single-room hospitalization environment was confirmed as an important factor for patients' psychological stability and maximizing treatment effects.

View Source 2024
Cross-Sectional Private Inpatient Room

Effect of Single-Room Korean Medicine Inpatient Treatment Environment on Patient Satisfaction and Treatment Compliance

Cho YK, Lee HJ, Park JM, et al. Patient Preference and Adherence (2024)
250 subjects Participants
Satisfaction 92.3% Single Room Satisfaction
Compliance 18% improvement Treatment Compliance Improvement

Summary

Two hundred fifty Korean medicine hospital inpatients were divided into single rooms and multi-bed rooms, and patient satisfaction, sleep quality, and treatment compliance were compared. Single-room patients showed significantly higher overall satisfaction and sleep quality, with higher participation in treatment programs.

Key Conclusion

The single-room hospitalization environment was confirmed as an important factor for patients' psychological stability and maximizing treatment effects.

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Cohort Study Private Inpatient Room

Integrated Effects of Korean Medicine Inpatient Treatment for Postoperative Convalescence Patients: A Cohort Study

Park GY, Song YK, Lee EJ, et al.

Integrative Medicine Research (2023)

95 subjects Participants
Recovery time 23% shortened Recovery Promotion
6 months Follow-up Period

Postoperative Korean medicine inpatient treatment is effective in shortening recovery time and promoting functional recovery.

View Source 2023
Cohort Study Private Inpatient Room

Integrated Effects of Korean Medicine Inpatient Treatment for Postoperative Convalescence Patients: A Cohort Study

Park GY, Song YK, Lee EJ, et al. Integrative Medicine Research (2023)
95 subjects Participants
Recovery time 23% shortened Recovery Promotion
6 months Follow-up Period

Summary

Recovery progress was tracked for 6 months in 95 patients transferred to Korean medicine hospitals after orthopedic surgery. The patient group receiving combined acupuncture, herbal medicine, and chuna treatment showed faster pain reduction and joint range of motion recovery.

Key Conclusion

Postoperative Korean medicine inpatient treatment is effective in shortening recovery time and promoting functional recovery.

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Cohort Study Private Inpatient Room

Effect of Korean Medicine Intensive Inpatient Treatment on Surgery Avoidance Rate in Lumbar Disc Herniation Patients

Jung SH, Shin BC, Lim BM, et al.

Spine Journal (2024)

78 subjects Participants
67.9% Surgery Avoidance Rate
12 months Follow-up Period

Korean medicine intensive inpatient treatment can be an effective alternative for non-surgical management of lumbar disc herniation patients.

View Source 2024
Cohort Study Private Inpatient Room

Effect of Korean Medicine Intensive Inpatient Treatment on Surgery Avoidance Rate in Lumbar Disc Herniation Patients

Jung SH, Shin BC, Lim BM, et al. Spine Journal (2024)
78 subjects Participants
67.9% Surgery Avoidance Rate
12 months Follow-up Period

Summary

Surgery decision outcomes were tracked in 78 lumbar disc herniation patients recommended for surgery who received Korean medicine hospital intensive inpatient treatment (acupuncture, pharmacopuncture, herbal medicine, chuna). After 12 months, 67.9% of patients successfully returned to daily activities without surgery.

Key Conclusion

Korean medicine intensive inpatient treatment can be an effective alternative for non-surgical management of lumbar disc herniation patients.

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Before-After Private Inpatient Room

Effect of an Integrated Management Program for Fall Prevention in Korean Medicine Hospital Inpatients

Kim MJ, Yoon YI, Lee SH, et al.

BMC Health Services Research (2023)

400 subjects Target Patients
Falls 62% reduction Preventive Effect
12 months Implementation Period

A personalized fall prevention program utilizing Korean medicine constitutional assessment is effective for inpatient safety management.

View Source 2023
Before-After Private Inpatient Room

Effect of an Integrated Management Program for Fall Prevention in Korean Medicine Hospital Inpatients

Kim MJ, Yoon YI, Lee SH, et al. BMC Health Services Research (2023)
400 subjects Target Patients
Falls 62% reduction Preventive Effect
12 months Implementation Period

Summary

A Korean medicine constitutional assessment-based fall prevention program was implemented for 400 Korean medicine hospital inpatients, and fall incidence rates were compared. After program implementation, fall incidence during hospitalization decreased by 62%.

Key Conclusion

A personalized fall prevention program utilizing Korean medicine constitutional assessment is effective for inpatient safety management.

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