금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
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Total 1642 papers

Narrative Review ENT Disorders

Narrative Review of Acupuncture Effects for Nasal Obstruction Related to Deviated Nasal Septum

정해인, 이광수, 김나연, et al.

Korean Journal of Acupuncture (2023)

8 studies Reviewed papers
6 acupoints Major acupoints used
73% Mean symptom improvement rate

Acupuncture can be utilized as a conservative treatment for nasal obstruction symptoms in patients with deviated nasal septum, and well-designed clinical trials are needed in the future.

Narrative Review ENT Disorders

Narrative Review of Acupuncture Effects for Nasal Obstruction Related to Deviated Nasal Septum

정해인, 이광수, 김나연, et al. Korean Journal of Acupuncture (2023)
8 studies Reviewed papers
6 acupoints Major acupoints used
73% Mean symptom improvement rate

Summary

A comprehensive review of treatment mechanisms and clinical evidence of acupuncture for nasal obstruction symptoms due to deviated nasal septum. Mechanisms of nasal mucosal blood flow modulation at acupoints such as LI20, LI4, and GV23, and nasal airway patency improvement effects were analyzed, with potential as conservative treatment before and after surgery discussed.

Key Conclusion

Acupuncture can be utilized as a conservative treatment for nasal obstruction symptoms in patients with deviated nasal septum, and well-designed clinical trials are needed in the future.

Case Study ENT Disorders

Effects of Nasal Irrigation and Herbal Medicine Combined Treatment for Chronic Rhinitis: A Case Report of 7 Cases

오승현, 김진아, 박동우, et al.

한방안이비인후피부과학회지 (2024)

61% TNSS reduction rate
7 patients Number of cases
8 weeks Treatment duration

Combined nasal irrigation and herbal medicine treatment shows synergistic effects in symptom relief of chronic rhinitis patients, and large-scale studies are warranted.

Case Study ENT Disorders

Effects of Nasal Irrigation and Herbal Medicine Combined Treatment for Chronic Rhinitis: A Case Report of 7 Cases

오승현, 김진아, 박동우, et al. 한방안이비인후피부과학회지 (2024)
61% TNSS reduction rate
7 patients Number of cases
8 weeks Treatment duration

Summary

A case report on 7 patients with chronic rhinitis of 6 months or more duration who received combined saline nasal irrigation and modified Changi-san for 8 weeks. All patients showed average 61% reduction in Total Nasal Symptom Score (TNSS), with particularly notable improvements in nasal obstruction and postnasal drip symptoms.

Key Conclusion

Combined nasal irrigation and herbal medicine treatment shows synergistic effects in symptom relief of chronic rhinitis patients, and large-scale studies are warranted.

Cross-Sectional ENT Disorders

Immediate and Sustained Effects of Nasal Pharmacopuncture for Allergic Rhinitis: A Cross-Sectional Study

이현주, 김수한, 정다빈, et al.

대한침구의학회지 (2023)

57.4% Nasal congestion VAS reduction
156 patients Study population
91% Patient satisfaction

Nasal pharmacopuncture treatment shows immediate relief effects for major symptoms of allergic rhinitis and is a treatment with high patient satisfaction.

Cross-Sectional ENT Disorders

Immediate and Sustained Effects of Nasal Pharmacopuncture for Allergic Rhinitis: A Cross-Sectional Study

이현주, 김수한, 정다빈, et al. 대한침구의학회지 (2023)
57.4% Nasal congestion VAS reduction
156 patients Study population
91% Patient satisfaction

Summary

A cross-sectional analysis of symptom changes before and after perinasal pharmacopuncture (Coptis-Schizonepeta extract) in 156 patients with allergic rhinitis. Nasal congestion VAS decreased from average 6.8 to 2.9 immediately after treatment, with significant improvements in sneeze frequency and rhinorrhea.

Key Conclusion

Nasal pharmacopuncture treatment shows immediate relief effects for major symptoms of allergic rhinitis and is a treatment with high patient satisfaction.

Meta-Analysis Respiratory Conditions

Systematic Review and Meta-Analysis of Herbal Medicine Treatment for Allergic Asthma

김유진, 박현수, 이정민, et al.

Phytomedicine (2024)

16 studies Analyzed studies
1,284 patients Total study population
4.1 points ACT score improvement

Herbal medicine treatment shows positive effects on symptom control improvement and immune indicator improvement in allergic asthma and can be utilized as adjunct to standard treatment.

Meta-Analysis Respiratory Conditions

Systematic Review and Meta-Analysis of Herbal Medicine Treatment for Allergic Asthma

김유진, 박현수, 이정민, et al. Phytomedicine (2024)
16 studies Analyzed studies
1,284 patients Total study population
4.1 points ACT score improvement

Summary

Sixteen RCTs (total 1,284 patients) evaluating herbal medicine treatment for allergic asthma were meta-analyzed. The herbal medicine combination group showed significantly improved Asthma Control Test (ACT) scores, with decreasing trends in serum IgE levels.

Key Conclusion

Herbal medicine treatment shows positive effects on symptom control improvement and immune indicator improvement in allergic asthma and can be utilized as adjunct to standard treatment.

RCT Respiratory Conditions

Effect of Combined Acupuncture and Moxibustion for Exercise-Induced Asthma: A Randomized Controlled Trial

조현우, 이다은, 박상기, et al.

Acupuncture in Medicine (2023)

42% Inhaler use reduction
74 patients Study population
12 weeks Treatment duration

Combined acupuncture and moxibustion is effective in alleviating bronchial hyperresponsiveness and reducing rescue inhaler dependence in exercise-induced asthma patients.

RCT Respiratory Conditions

Effect of Combined Acupuncture and Moxibustion for Exercise-Induced Asthma: A Randomized Controlled Trial

조현우, 이다은, 박상기, et al. Acupuncture in Medicine (2023)
42% Inhaler use reduction
74 patients Study population
12 weeks Treatment duration

Summary

In 74 adult patients diagnosed with exercise-induced asthma, an acupuncture plus moxibustion combination group was compared with an inhaler-alone group. After 12 weeks, the combination group showed significantly reduced post-exercise FEV1 decline and 42% reduction in inhaler use frequency.

Key Conclusion

Combined acupuncture and moxibustion is effective in alleviating bronchial hyperresponsiveness and reducing rescue inhaler dependence in exercise-induced asthma patients.

Before-After Respiratory Conditions

Clinical Effect of Modified Socheongryong-tang for Pediatric Asthma with Nocturnal Cough

한미경, 정성훈, 김보라, et al.

대한한방소아과학회지 (2024)

75.9% Nocturnal cough reduction rate
62 patients Study population
15.3% PEFR improvement rate

Modified Socheongryong-tang is an effective Korean medicine treatment that significantly reduces nocturnal cough frequency and improves pulmonary function in pediatric asthma.

Before-After Respiratory Conditions

Clinical Effect of Modified Socheongryong-tang for Pediatric Asthma with Nocturnal Cough

한미경, 정성훈, 김보라, et al. 대한한방소아과학회지 (2024)
75.9% Nocturnal cough reduction rate
62 patients Study population
15.3% PEFR improvement rate

Summary

A pre-post comparison study administering modified Socheongryong-tang for 8 weeks to 62 pediatric asthma patients with 3 or more weekly nocturnal coughs. After treatment, weekly nocturnal cough episodes decreased from 5.8 to 1.4, and PEFR (peak expiratory flow rate) improved by 15.3%.

Key Conclusion

Modified Socheongryong-tang is an effective Korean medicine treatment that significantly reduces nocturnal cough frequency and improves pulmonary function in pediatric asthma.

Meta-Analysis Respiratory Conditions

Effect of Acupuncture for Chronic Cough Patients: A Meta-Analysis

박지은, 김태호, 이수연, et al.

Complementary Therapies in Medicine (2023)

3.2 points LCQ score improvement
9 studies Analyzed studies
54% Cough frequency reduction

Acupuncture shows significant efficacy in quality of life improvement and cough frequency reduction in chronic cough patients, and can be used complementarily to conventional treatment.

Meta-Analysis Respiratory Conditions

Effect of Acupuncture for Chronic Cough Patients: A Meta-Analysis

박지은, 김태호, 이수연, et al. Complementary Therapies in Medicine (2023)
3.2 points LCQ score improvement
9 studies Analyzed studies
54% Cough frequency reduction

Summary

Nine RCTs evaluating acupuncture for chronic cough lasting more than 8 weeks were meta-analyzed. The acupuncture group showed average 3.2-point improvement in Leicester Cough Questionnaire (LCQ) scores compared to controls, with significantly reduced cough frequency.

Key Conclusion

Acupuncture shows significant efficacy in quality of life improvement and cough frequency reduction in chronic cough patients, and can be used complementarily to conventional treatment.

Cohort Study Respiratory Conditions

Bojungikgi-tang Combination Treatment for Post-COVID-19 (Long COVID) Fatigue and Dyspnea: A Prospective Cohort Study

이상훈, 김혜진, 박영민, et al.

대한한의학회지 (2024)

42% Fatigue scale improvement
124 patients Study population
58 m 6-min walk distance increase

Bojungikgi-tang shows promising potential as adjunctive treatment for fatigue and dyspnea symptom improvement in long COVID patients.

Cohort Study Respiratory Conditions

Bojungikgi-tang Combination Treatment for Post-COVID-19 (Long COVID) Fatigue and Dyspnea: A Prospective Cohort Study

이상훈, 김혜진, 박영민, et al. 대한한의학회지 (2024)
42% Fatigue scale improvement
124 patients Study population
58 m 6-min walk distance increase

Summary

A prospective cohort study comparing Bojungikgi-tang combination administration versus standard care in 124 patients with fatigue and dyspnea persisting more than 12 weeks after COVID-19 diagnosis. After 8 weeks of observation, the Bojungikgi-tang group showed 42% improvement in Chalder fatigue scale and significant increase in 6-minute walk distance.

Key Conclusion

Bojungikgi-tang shows promising potential as adjunctive treatment for fatigue and dyspnea symptom improvement in long COVID patients.

RCT Respiratory Conditions

Therapeutic Effect of Maekmundong-tang on Persistent Post-Influenza Cough: A Randomized Controlled Trial

정윤서, 최민규, 한지영, et al.

Journal of Ethnopharmacology (2023)

68% Cough frequency reduction
86 patients Study population
4 weeks Treatment duration

Maekmundong-tang shows significant cough reduction effect versus placebo in persistent post-influenza cough, providing evidence for Korean medicine treatment of post-infectious cough.

RCT Respiratory Conditions

Therapeutic Effect of Maekmundong-tang on Persistent Post-Influenza Cough: A Randomized Controlled Trial

정윤서, 최민규, 한지영, et al. Journal of Ethnopharmacology (2023)
68% Cough frequency reduction
86 patients Study population
4 weeks Treatment duration

Summary

Maekmundong-tang treatment versus placebo was compared in 86 patients with cough persisting more than 3 weeks after influenza infection. After 4 weeks of treatment, the Maekmundong-tang group showed 68% reduction in cough frequency, with significant improvements in throat dryness and nocturnal cough episodes.

Key Conclusion

Maekmundong-tang shows significant cough reduction effect versus placebo in persistent post-influenza cough, providing evidence for Korean medicine treatment of post-infectious cough.

Systematic Review Respiratory Conditions

Effect of Early Galgeun-tang Administration on Initial Cold Symptoms: A Systematic Review

김동현, 박수진, 이재훈, et al.

대한한방내과학회지 (2024)

2.3 days Symptom duration reduction
12 studies Analyzed studies
87% Symptom improvement rate

Early Galgeun-tang administration is effective for rapid cold symptom relief and reduced illness duration, with a favorable safety profile.

Systematic Review Respiratory Conditions

Effect of Early Galgeun-tang Administration on Initial Cold Symptoms: A Systematic Review

김동현, 박수진, 이재훈, et al. 대한한방내과학회지 (2024)
2.3 days Symptom duration reduction
12 studies Analyzed studies
87% Symptom improvement rate

Summary

Twelve studies on the effect of Galgeun-tang administration within 48 hours of cold onset were systematically analyzed. The early administration group showed an average 2.3-day reduction in symptom duration, with significantly faster fever resolution time. Side effect reports were limited to only 3 cases of mild gastrointestinal disturbance.

Key Conclusion

Early Galgeun-tang administration is effective for rapid cold symptom relief and reduced illness duration, with a favorable safety profile.

Before-After Geum! Maek! Capsule Diet

Effect of Herbal Medicine Treatment on Gut Microbiome Diversity in Obese Patients: A Pre-Post Comparison Study

Oh SJ, Moon HW, Choi JY, et al.

Gut Microbes (2023)

24% Microbiome Diversity Increase
3.2 times Beneficial Bacteria Increase
41% Endotoxin Reduction

Herbal medicine treatment diversifies the gut microbiome ecosystem in obese patients and reduces metabolic endotoxin, contributing to weight regulation through gut-metabolic axis improvement.

Before-After Geum! Maek! Capsule Diet

Effect of Herbal Medicine Treatment on Gut Microbiome Diversity in Obese Patients: A Pre-Post Comparison Study

Oh SJ, Moon HW, Choi JY, et al. Gut Microbes (2023)
24% Microbiome Diversity Increase
3.2 times Beneficial Bacteria Increase
41% Endotoxin Reduction

Summary

A pre-post comparison study administered constitutional tailored herbal medicine for 12 weeks to 66 obese patients with BMI ≥28. In 16S rRNA analysis, gut microbiome diversity (Shannon index) increased by 24%, and the Firmicutes/Bacteroidetes ratio normalized. The Akkermansia muciniphila proportion increased 3.2-fold, and blood LPS (endotoxin) decreased by 41%, with improvement in metabolic endotoxemia.

Key Conclusion

Herbal medicine treatment diversifies the gut microbiome ecosystem in obese patients and reduces metabolic endotoxin, contributing to weight regulation through gut-metabolic axis improvement.

RCT Geum! Maek! Capsule Diet

Abdominal Obesity Reduction Effect of Korean Medicine Thread Embedding Therapy: A Randomized Controlled Trial

Kwon CY, Yoon SH, Lee BH, et al.

Journal of Alternative and Complementary Medicine (2024)

5.6cm Waist Circumference Reduction
18% Subcutaneous Fat Reduction
2 times vs Monotherapy

The combination of thread embedding therapy and herbal medicine demonstrates synergistic effects on abdominal obesity, particularly being effective for local fat reduction.

RCT Geum! Maek! Capsule Diet

Abdominal Obesity Reduction Effect of Korean Medicine Thread Embedding Therapy: A Randomized Controlled Trial

Kwon CY, Yoon SH, Lee BH, et al. Journal of Alternative and Complementary Medicine (2024)
5.6cm Waist Circumference Reduction
18% Subcutaneous Fat Reduction
2 times vs Monotherapy

Summary

An 8-week randomized controlled trial compared a thread embedding + herbal medicine group with a herbal medicine monotherapy group in 94 adults with abdominal obesity (waist circumference ≥90 cm in men, ≥85 cm in women). The thread embedding combined group showed an average 5.6 cm reduction in waist circumference, twice the effect of the herbal medicine monotherapy group (2.8 cm). Subcutaneous fat on abdominal CT decreased by 18%, and abdominal muscle tone improved significantly.

Key Conclusion

The combination of thread embedding therapy and herbal medicine demonstrates synergistic effects on abdominal obesity, particularly being effective for local fat reduction.