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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
RCT ENT Disorders

Effect of Combined Acupuncture and Voice Therapy for Vocal Cord Nodules: A Randomized Controlled Trial

Song MY, Choi TY, Shin BC, et al.

Journal of Voice (2023)

47% VHI Reduction Rate
74 subjects Participants
8 weeks Treatment Period

Adjunctive acupuncture promotes voice function recovery and nodule size reduction in vocal cord nodules.

View Source 2023
RCT ENT Disorders

Effect of Combined Acupuncture and Voice Therapy for Vocal Cord Nodules: A Randomized Controlled Trial

Song MY, Choi TY, Shin BC, et al. Journal of Voice (2023)
47% VHI Reduction Rate
74 subjects Participants
8 weeks Treatment Period

Summary

Seventy-four patients with vocal cord nodules were assigned to voice therapy monotherapy or voice therapy plus acupuncture combination groups for 8 weeks of treatment. The combination group demonstrated a 47% reduction in VHI (Voice Handicap Index), significantly superior to monotherapy (31%), with greater nodule size reduction also observed on laryngeal stroboscopy.

Key Conclusion

Adjunctive acupuncture promotes voice function recovery and nodule size reduction in vocal cord nodules.

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Narrative Review ENT Disorders

Narrative Review of Korean Medicine Treatment for Functional Voice Disorders

Park DI, Kim AR, Leem JT, et al.

Integrative Medicine Research (2024)

19 papers Reviewed Papers
85% Average Efficacy Rate
3.2 sec Average MPT Improvement

Korean medicine treatment has potential for improving various voice parameters in functional voice disorders, with standardized clinical trials required.

View Source 2024
Narrative Review ENT Disorders

Narrative Review of Korean Medicine Treatment for Functional Voice Disorders

Park DI, Kim AR, Leem JT, et al. Integrative Medicine Research (2024)
19 papers Reviewed Papers
85% Average Efficacy Rate
3.2 sec Average MPT Improvement

Summary

Nineteen articles on Korean medicine treatment for functional voice disorders were reviewed, with acupuncture (Renying, Tiantu, Hegu) and herbal medicines such as Hyangsayangwi-tang predominantly utilized. In multiple studies, maximum phonation time (MPT) and fundamental frequency stability improved, with significant reduction in vocal fatigue.

Key Conclusion

Korean medicine treatment has potential for improving various voice parameters in functional voice disorders, with standardized clinical trials required.

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Cross-Sectional ENT Disorders

Anti-inflammatory Effect of Modified Eungyo-san for Acute Laryngitis: A Cross-Sectional Study

Lim SH, Kang BK, You SS, et al.

동의생리병리학회지 (2023)

67% Pharyngeal Pain Reduction
79% Laryngeal Finding Improvement
82 subjects Participants

Modified Eungyo-san is effective for rapid symptom relief and laryngeal inflammatory finding improvement in acute laryngitis.

View Source 2023
Cross-Sectional ENT Disorders

Anti-inflammatory Effect of Modified Eungyo-san for Acute Laryngitis: A Cross-Sectional Study

Lim SH, Kang BK, You SS, et al. 동의생리병리학회지 (2023)
67% Pharyngeal Pain Reduction
79% Laryngeal Finding Improvement
82 subjects Participants

Summary

Eighty-two patients with acute laryngitis were compared for pharyngeal pain VAS, laryngoscopic findings, and serum inflammatory markers before and after modified Eungyo-san administration. After 5 days of treatment, pharyngeal pain decreased by an average of 67%, with marked improvement in laryngeal erythema and edema findings in 79%.

Key Conclusion

Modified Eungyo-san is effective for rapid symptom relief and laryngeal inflammatory finding improvement in acute laryngitis.

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RCT Mental Health

Serotonin Regulation Effect of Acupuncture Treatment in Depression Patients: A Randomized Controlled Trial

Kim SH, Park JY, Lee DH, et al.

Journal of Affective Disorders (2024)

52% HAM-D Reduction Rate
120 subjects Participants
8 weeks Treatment Period

Acupuncture treatment provides antidepressant effects by regulating serotonin metabolism in depression patients.

View Source 2024
RCT Mental Health

Serotonin Regulation Effect of Acupuncture Treatment in Depression Patients: A Randomized Controlled Trial

Kim SH, Park JY, Lee DH, et al. Journal of Affective Disorders (2024)
52% HAM-D Reduction Rate
120 subjects Participants
8 weeks Treatment Period

Summary

One hundred twenty patients with major depressive disorder were compared between acupuncture and sham acupuncture groups for 8 weeks. HAM-D scores decreased by 52% and serum serotonin levels increased significantly in the acupuncture group.

Key Conclusion

Acupuncture treatment provides antidepressant effects by regulating serotonin metabolism in depression patients.

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Systematic Review Mental Health

Systematic Review of Herbal Medicine (Sihogayonggolmoryeo-tang) Treatment for Panic Disorder

Lee JH, Choi AR, Yoon SJ, et al.

Phytomedicine (2023)

14 studies Analyzed Studies
Panic attacks reduced Main Effect
SSRI combination Treatment Strategy

Sihogayonggolmoryeo-tang effectively reduces panic attack frequency and intensity as adjunctive treatment for panic disorder.

View Source 2023
Systematic Review Mental Health

Systematic Review of Herbal Medicine (Sihogayonggolmoryeo-tang) Treatment for Panic Disorder

Lee JH, Choi AR, Yoon SJ, et al. Phytomedicine (2023)
14 studies Analyzed Studies
Panic attacks reduced Main Effect
SSRI combination Treatment Strategy

Summary

Fourteen studies evaluating the effect of Sihogayonggolmoryeo-tang for panic disorder were systematically reviewed. Compared with SSRI alone, the herbal medicine combined group showed significant reduction in panic attack frequency.

Key Conclusion

Sihogayonggolmoryeo-tang effectively reduces panic attack frequency and intensity as adjunctive treatment for panic disorder.

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Meta-Analysis Mental Health

Effect of Auricular Acupuncture for Generalized Anxiety Disorder Patients: A Meta-Analysis

Shin MK, Han CH, Jung WS, et al.

Complementary Therapies in Medicine (2024)

16 studies Analyzed RCTs
-3.82 GAD-7 MD
Sleep improvement Additional Effect

Auricular acupuncture treatment is effective for improving anxiety symptoms and accompanying sleep disorders as non-pharmacological treatment for generalized anxiety disorder.

View Source 2024
Meta-Analysis Mental Health

Effect of Auricular Acupuncture for Generalized Anxiety Disorder Patients: A Meta-Analysis

Shin MK, Han CH, Jung WS, et al. Complementary Therapies in Medicine (2024)
16 studies Analyzed RCTs
-3.82 GAD-7 MD
Sleep improvement Additional Effect

Summary

A meta-analysis of 16 RCTs evaluating the effect of auricular acupuncture treatment for generalized anxiety disorder. Auricular acupuncture treatment showed significant effects on GAD-7 score reduction (MD: -3.82) and sleep quality improvement.

Key Conclusion

Auricular acupuncture treatment is effective for improving anxiety symptoms and accompanying sleep disorders as non-pharmacological treatment for generalized anxiety disorder.

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Before-After Mental Health

Effect of Korean Medicine Combined Treatment for Hwa-Byung Patients: A Pre-Post Comparison Study

Kang BK, Moon SJ, Cho HJ, et al.

Journal of Korean Medicine (2023)

58% Hwa-byung Scale Reduction
85 subjects Participants
Cortisol normalization Physiological Improvement

Korean medicine combined treatment simultaneously improves psychological symptoms and physiological indicators of hwa-byung.

View Source 2023
Before-After Mental Health

Effect of Korean Medicine Combined Treatment for Hwa-Byung Patients: A Pre-Post Comparison Study

Kang BK, Moon SJ, Cho HJ, et al. Journal of Korean Medicine (2023)
58% Hwa-byung Scale Reduction
85 subjects Participants
Cortisol normalization Physiological Improvement

Summary

Herbal medicine (Gamisoyo-san) + acupuncture + counseling were applied for 8 weeks to 85 hwa-byung diagnosed patients. Hwa-byung scale scores decreased by 58%, and cortisol diurnal variation normalized.

Key Conclusion

Korean medicine combined treatment simultaneously improves psychological symptoms and physiological indicators of hwa-byung.

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Before-After Mental Health

Amygdala Activity Regulation of Acupuncture Treatment in PTSD Patients: An fMRI Study

Park SJ, Lee EH, Kim TH, et al.

NeuroImage: Clinical (2024)

40 subjects Participants
Amygdala activity↓ Brain Imaging Change
12 sessions Treatment Sessions

Acupuncture treatment alleviates fear responses by regulating the amygdala-prefrontal network, the core neural circuit of PTSD.

View Source 2024
Before-After Mental Health

Amygdala Activity Regulation of Acupuncture Treatment in PTSD Patients: An fMRI Study

Park SJ, Lee EH, Kim TH, et al. NeuroImage: Clinical (2024)
40 subjects Participants
Amygdala activity↓ Brain Imaging Change
12 sessions Treatment Sessions

Summary

Brain activity changes were measured by fMRI after 12 acupuncture sessions in 40 post-traumatic stress disorder patients. Amygdala hyperactivity decreased and prefrontal-amygdala connectivity improved after acupuncture treatment.

Key Conclusion

Acupuncture treatment alleviates fear responses by regulating the amygdala-prefrontal network, the core neural circuit of PTSD.

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Cohort Study Mental Health

Cohort Study of Herbal Medicine Treatment for Social Anxiety Disorder

Oh JH, Yoo TW, Baek YH, et al.

Social Psychiatry and Psychiatric Epidemiology (2023)

43% LSAS Reduction
140 subjects Participants
16 weeks Follow-up Period

Herbal medicine treatment effectively reduces anxiety symptoms and avoidance behaviors in social anxiety disorder.

View Source 2023
Cohort Study Mental Health

Cohort Study of Herbal Medicine Treatment for Social Anxiety Disorder

Oh JH, Yoo TW, Baek YH, et al. Social Psychiatry and Psychiatric Epidemiology (2023)
43% LSAS Reduction
140 subjects Participants
16 weeks Follow-up Period

Summary

One hundred forty patients with social anxiety disorder were followed for 16 weeks, divided into herbal medicine treatment (modified Banhahubak-tang) and waiting list groups. LSAS scores decreased by 43% in the herbal medicine group, and social avoidance behaviors significantly improved.

Key Conclusion

Herbal medicine treatment effectively reduces anxiety symptoms and avoidance behaviors in social anxiety disorder.

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RCT Mental Health

Effect of Combined Acupuncture and Cognitive Behavioral Therapy for Insomnia: A Randomized Controlled Trial

Ryu BH, Song JH, Kim CH, et al.

Sleep Medicine (2024)

68% ISI Reduction Rate
100 subjects Participants
8 weeks Treatment Period

The combination of acupuncture treatment and CBT-I shows superior synergistic effects to single treatments in chronic insomnia.

View Source 2024
RCT Mental Health

Effect of Combined Acupuncture and Cognitive Behavioral Therapy for Insomnia: A Randomized Controlled Trial

Ryu BH, Song JH, Kim CH, et al. Sleep Medicine (2024)
68% ISI Reduction Rate
100 subjects Participants
8 weeks Treatment Period

Summary

One hundred patients with chronic insomnia were divided into acupuncture + CBT-I, CBT-I alone, and acupuncture alone groups and compared for 8 weeks. ISI scores decreased by 68% in the combined group, showing the best effect.

Key Conclusion

The combination of acupuncture treatment and CBT-I shows superior synergistic effects to single treatments in chronic insomnia.

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Cross-Sectional Mental Health

Cross-Sectional Analysis of Korean Medicine Interventions for Worker Burnout Syndrome

Lim CS, Jung SY, Han DH, et al.

Occupational Medicine (2023)

250 subjects Participants
35% Emotional exhaustion↓
MBI Assessment Tool

Workers utilizing Korean medicine interventions show significantly lower burnout symptoms, suggesting effects of preventive health management.

View Source 2023
Cross-Sectional Mental Health

Cross-Sectional Analysis of Korean Medicine Interventions for Worker Burnout Syndrome

Lim CS, Jung SY, Han DH, et al. Occupational Medicine (2023)
250 subjects Participants
35% Emotional exhaustion↓
MBI Assessment Tool

Summary

Korean medicine treatment utilization patterns and MBI scores were analyzed in 250 workers complaining of burnout symptoms. Emotional exhaustion scores were 35% lower and personal accomplishment higher in the Korean medicine intervention user group.

Key Conclusion

Workers utilizing Korean medicine interventions show significantly lower burnout symptoms, suggesting effects of preventive health management.

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Narrative Review Mental Health

Effect of Electroacupuncture Treatment for Obsessive-Compulsive Disorder: A Narrative Review

Cho WS, Park EJ, Lee AR, et al.

CNS Neuroscience & Therapeutics (2024)

22 sources Reviewed Literature
Y-BOCS reduction Main Effect
Serotonin Mechanism

Electroacupuncture treatment shows potential as adjunctive treatment for obsessive-compulsive disorder, and large-scale RCTs are needed.

View Source 2024
Narrative Review Mental Health

Effect of Electroacupuncture Treatment for Obsessive-Compulsive Disorder: A Narrative Review

Cho WS, Park EJ, Lee AR, et al. CNS Neuroscience & Therapeutics (2024)
22 sources Reviewed Literature
Y-BOCS reduction Main Effect
Serotonin Mechanism

Summary

Twenty-two articles on the effect of electroacupuncture treatment for obsessive-compulsive disorder were narratively reviewed. Electroacupuncture showed positive effects on Y-BOCS score reduction and serotonin reuptake regulation.

Key Conclusion

Electroacupuncture treatment shows potential as adjunctive treatment for obsessive-compulsive disorder, and large-scale RCTs are needed.

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