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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Meta-Analysis ENT Disorders

Systematic Review and Meta-analysis of Korean Medicine Treatment for Nasal Polyps

Moon SK, Jang JY, Woo CH, et al.

Rhinology (2024)

32% Polyp Size Reduction
11% Recurrence Rate (Treatment)
16 studies Analyzed Studies

Korean medicine treatment is an effective complementary strategy for nasal polyp size reduction and postoperative recurrence prevention.

View Source 2024
Meta-Analysis ENT Disorders

Systematic Review and Meta-analysis of Korean Medicine Treatment for Nasal Polyps

Moon SK, Jang JY, Woo CH, et al. Rhinology (2024)
32% Polyp Size Reduction
11% Recurrence Rate (Treatment)
16 studies Analyzed Studies

Summary

Sixteen clinical studies (1,234 subjects total) evaluating Korean medicine treatment (herbal medicine, acupuncture, pharmacopuncture) for nasal polyps were meta-analyzed. The Korean medicine group demonstrated an average 32% reduction in polyp size, with herbal medicine administration for postoperative recurrence prevention showing significantly lower recurrence rates (11%) compared with controls (28%).

Key Conclusion

Korean medicine treatment is an effective complementary strategy for nasal polyp size reduction and postoperative recurrence prevention.

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Cohort Study ENT Disorders

Symptom Alleviation Effect of Acupuncture for Nasal Obstruction Accompanying Septal Deviation: A Cohort Study

Yoo DG, Shin SH, Lee JY, et al.

Clinical Otolaryngology (2023)

38% NOSE Score Improvement
22% Nasal Cross-Section Increase
92 subjects Participants

Acupuncture significantly alleviates nasal obstruction symptoms as a conservative pre-surgical treatment for septal deviation.

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Cohort Study ENT Disorders

Symptom Alleviation Effect of Acupuncture for Nasal Obstruction Accompanying Septal Deviation: A Cohort Study

Yoo DG, Shin SH, Lee JY, et al. Clinical Otolaryngology (2023)
38% NOSE Score Improvement
22% Nasal Cross-Section Increase
92 subjects Participants

Summary

Ninety-two patients with septal deviation complaining of nasal obstruction received acupuncture at Yingxiang (LI20), Bitong (EX-HN8), and Yintang (EX-HN3) for 6 weeks. NOSE questionnaire scores improved by an average of 38%, and minimum cross-sectional area on acoustic rhinometry (AR) increased by 22%.

Key Conclusion

Acupuncture significantly alleviates nasal obstruction symptoms as a conservative pre-surgical treatment for septal deviation.

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RCT ENT Disorders

Therapeutic Effect of Modified Okbyeongpung-san for Allergic Rhinitis: A Multicenter Randomized Controlled Trial

Kim HJ, Cho JH, Nam DH, et al.

Allergy, Asthma & Immunology Research (2024)

58% TNSS Reduction Rate
156 subjects Participants
p=0.042 Recurrence Significance

Modified Okbyeongpung-san demonstrates equivalent efficacy to conventional medication in allergic rhinitis symptom control and is superior in long-term recurrence prevention.

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RCT ENT Disorders

Therapeutic Effect of Modified Okbyeongpung-san for Allergic Rhinitis: A Multicenter Randomized Controlled Trial

Kim HJ, Cho JH, Nam DH, et al. Allergy, Asthma & Immunology Research (2024)
58% TNSS Reduction Rate
156 subjects Participants
p=0.042 Recurrence Significance

Summary

One hundred fifty-six patients with perennial allergic rhinitis were randomized to modified Okbyeongpung-san or loratadine groups for 8 weeks of treatment. The herbal group's TNSS (Total Nasal Symptom Score) reduction rate was 58%, non-inferior to loratadine (49%), with significantly lower recurrence rates 4 weeks after treatment completion.

Key Conclusion

Modified Okbyeongpung-san demonstrates equivalent efficacy to conventional medication in allergic rhinitis symptom control and is superior in long-term recurrence prevention.

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RCT Pediatric / Adolescent Care

Randomized Controlled Trial of Combined Herbal Medicine and Behavioral Therapy for Pediatric ADHD

Kim KH, Ahn TW, Lee SG, et al.

Journal of Child Psychology and Psychiatry (2023)

47% K-ARS Reduction
80 subjects Participants
Attention improvement Key Effect

Combined herbal medicine and behavioral therapy effectively improves attention deficit symptoms in pediatric ADHD.

View Source 2023
RCT Pediatric / Adolescent Care

Randomized Controlled Trial of Combined Herbal Medicine and Behavioral Therapy for Pediatric ADHD

Kim KH, Ahn TW, Lee SG, et al. Journal of Child Psychology and Psychiatry (2023)
47% K-ARS Reduction
80 subjects Participants
Attention improvement Key Effect

Summary

Eighty ADHD children were compared between herbal medicine (modified Guibi-tang) + behavioral therapy and behavioral therapy alone groups for 8 weeks. K-ARS scores decreased by 47% and attention span significantly improved in the combined group.

Key Conclusion

Combined herbal medicine and behavioral therapy effectively improves attention deficit symptoms in pediatric ADHD.

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Narrative Review Mental Health

Effect of Electroacupuncture Treatment for Obsessive-Compulsive Disorder: A Narrative Review

Cho WS, Park EJ, Lee AR, et al.

CNS Neuroscience & Therapeutics (2024)

22 sources Reviewed Literature
Y-BOCS reduction Main Effect
Serotonin Mechanism

Electroacupuncture treatment shows potential as adjunctive treatment for obsessive-compulsive disorder, and large-scale RCTs are needed.

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Narrative Review Mental Health

Effect of Electroacupuncture Treatment for Obsessive-Compulsive Disorder: A Narrative Review

Cho WS, Park EJ, Lee AR, et al. CNS Neuroscience & Therapeutics (2024)
22 sources Reviewed Literature
Y-BOCS reduction Main Effect
Serotonin Mechanism

Summary

Twenty-two articles on the effect of electroacupuncture treatment for obsessive-compulsive disorder were narratively reviewed. Electroacupuncture showed positive effects on Y-BOCS score reduction and serotonin reuptake regulation.

Key Conclusion

Electroacupuncture treatment shows potential as adjunctive treatment for obsessive-compulsive disorder, and large-scale RCTs are needed.

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Cross-Sectional Mental Health

Cross-Sectional Analysis of Korean Medicine Interventions for Worker Burnout Syndrome

Lim CS, Jung SY, Han DH, et al.

Occupational Medicine (2023)

250 subjects Participants
35% Emotional exhaustion↓
MBI Assessment Tool

Workers utilizing Korean medicine interventions show significantly lower burnout symptoms, suggesting effects of preventive health management.

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Cross-Sectional Mental Health

Cross-Sectional Analysis of Korean Medicine Interventions for Worker Burnout Syndrome

Lim CS, Jung SY, Han DH, et al. Occupational Medicine (2023)
250 subjects Participants
35% Emotional exhaustion↓
MBI Assessment Tool

Summary

Korean medicine treatment utilization patterns and MBI scores were analyzed in 250 workers complaining of burnout symptoms. Emotional exhaustion scores were 35% lower and personal accomplishment higher in the Korean medicine intervention user group.

Key Conclusion

Workers utilizing Korean medicine interventions show significantly lower burnout symptoms, suggesting effects of preventive health management.

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RCT Mental Health

Effect of Combined Acupuncture and Cognitive Behavioral Therapy for Insomnia: A Randomized Controlled Trial

Ryu BH, Song JH, Kim CH, et al.

Sleep Medicine (2024)

68% ISI Reduction Rate
100 subjects Participants
8 weeks Treatment Period

The combination of acupuncture treatment and CBT-I shows superior synergistic effects to single treatments in chronic insomnia.

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RCT Mental Health

Effect of Combined Acupuncture and Cognitive Behavioral Therapy for Insomnia: A Randomized Controlled Trial

Ryu BH, Song JH, Kim CH, et al. Sleep Medicine (2024)
68% ISI Reduction Rate
100 subjects Participants
8 weeks Treatment Period

Summary

One hundred patients with chronic insomnia were divided into acupuncture + CBT-I, CBT-I alone, and acupuncture alone groups and compared for 8 weeks. ISI scores decreased by 68% in the combined group, showing the best effect.

Key Conclusion

The combination of acupuncture treatment and CBT-I shows superior synergistic effects to single treatments in chronic insomnia.

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Cohort Study Mental Health

Cohort Study of Herbal Medicine Treatment for Social Anxiety Disorder

Oh JH, Yoo TW, Baek YH, et al.

Social Psychiatry and Psychiatric Epidemiology (2023)

43% LSAS Reduction
140 subjects Participants
16 weeks Follow-up Period

Herbal medicine treatment effectively reduces anxiety symptoms and avoidance behaviors in social anxiety disorder.

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Cohort Study Mental Health

Cohort Study of Herbal Medicine Treatment for Social Anxiety Disorder

Oh JH, Yoo TW, Baek YH, et al. Social Psychiatry and Psychiatric Epidemiology (2023)
43% LSAS Reduction
140 subjects Participants
16 weeks Follow-up Period

Summary

One hundred forty patients with social anxiety disorder were followed for 16 weeks, divided into herbal medicine treatment (modified Banhahubak-tang) and waiting list groups. LSAS scores decreased by 43% in the herbal medicine group, and social avoidance behaviors significantly improved.

Key Conclusion

Herbal medicine treatment effectively reduces anxiety symptoms and avoidance behaviors in social anxiety disorder.

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Before-After Mental Health

Amygdala Activity Regulation of Acupuncture Treatment in PTSD Patients: An fMRI Study

Park SJ, Lee EH, Kim TH, et al.

NeuroImage: Clinical (2024)

40 subjects Participants
Amygdala activity↓ Brain Imaging Change
12 sessions Treatment Sessions

Acupuncture treatment alleviates fear responses by regulating the amygdala-prefrontal network, the core neural circuit of PTSD.

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Before-After Mental Health

Amygdala Activity Regulation of Acupuncture Treatment in PTSD Patients: An fMRI Study

Park SJ, Lee EH, Kim TH, et al. NeuroImage: Clinical (2024)
40 subjects Participants
Amygdala activity↓ Brain Imaging Change
12 sessions Treatment Sessions

Summary

Brain activity changes were measured by fMRI after 12 acupuncture sessions in 40 post-traumatic stress disorder patients. Amygdala hyperactivity decreased and prefrontal-amygdala connectivity improved after acupuncture treatment.

Key Conclusion

Acupuncture treatment alleviates fear responses by regulating the amygdala-prefrontal network, the core neural circuit of PTSD.

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Before-After Mental Health

Effect of Korean Medicine Combined Treatment for Hwa-Byung Patients: A Pre-Post Comparison Study

Kang BK, Moon SJ, Cho HJ, et al.

Journal of Korean Medicine (2023)

58% Hwa-byung Scale Reduction
85 subjects Participants
Cortisol normalization Physiological Improvement

Korean medicine combined treatment simultaneously improves psychological symptoms and physiological indicators of hwa-byung.

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Before-After Mental Health

Effect of Korean Medicine Combined Treatment for Hwa-Byung Patients: A Pre-Post Comparison Study

Kang BK, Moon SJ, Cho HJ, et al. Journal of Korean Medicine (2023)
58% Hwa-byung Scale Reduction
85 subjects Participants
Cortisol normalization Physiological Improvement

Summary

Herbal medicine (Gamisoyo-san) + acupuncture + counseling were applied for 8 weeks to 85 hwa-byung diagnosed patients. Hwa-byung scale scores decreased by 58%, and cortisol diurnal variation normalized.

Key Conclusion

Korean medicine combined treatment simultaneously improves psychological symptoms and physiological indicators of hwa-byung.

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Meta-Analysis Mental Health

Effect of Auricular Acupuncture for Generalized Anxiety Disorder Patients: A Meta-Analysis

Shin MK, Han CH, Jung WS, et al.

Complementary Therapies in Medicine (2024)

16 studies Analyzed RCTs
-3.82 GAD-7 MD
Sleep improvement Additional Effect

Auricular acupuncture treatment is effective for improving anxiety symptoms and accompanying sleep disorders as non-pharmacological treatment for generalized anxiety disorder.

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Meta-Analysis Mental Health

Effect of Auricular Acupuncture for Generalized Anxiety Disorder Patients: A Meta-Analysis

Shin MK, Han CH, Jung WS, et al. Complementary Therapies in Medicine (2024)
16 studies Analyzed RCTs
-3.82 GAD-7 MD
Sleep improvement Additional Effect

Summary

A meta-analysis of 16 RCTs evaluating the effect of auricular acupuncture treatment for generalized anxiety disorder. Auricular acupuncture treatment showed significant effects on GAD-7 score reduction (MD: -3.82) and sleep quality improvement.

Key Conclusion

Auricular acupuncture treatment is effective for improving anxiety symptoms and accompanying sleep disorders as non-pharmacological treatment for generalized anxiety disorder.

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Systematic Review Mental Health

Systematic Review of Herbal Medicine (Sihogayonggolmoryeo-tang) Treatment for Panic Disorder

Lee JH, Choi AR, Yoon SJ, et al.

Phytomedicine (2023)

14 studies Analyzed Studies
Panic attacks reduced Main Effect
SSRI combination Treatment Strategy

Sihogayonggolmoryeo-tang effectively reduces panic attack frequency and intensity as adjunctive treatment for panic disorder.

View Source 2023
Systematic Review Mental Health

Systematic Review of Herbal Medicine (Sihogayonggolmoryeo-tang) Treatment for Panic Disorder

Lee JH, Choi AR, Yoon SJ, et al. Phytomedicine (2023)
14 studies Analyzed Studies
Panic attacks reduced Main Effect
SSRI combination Treatment Strategy

Summary

Fourteen studies evaluating the effect of Sihogayonggolmoryeo-tang for panic disorder were systematically reviewed. Compared with SSRI alone, the herbal medicine combined group showed significant reduction in panic attack frequency.

Key Conclusion

Sihogayonggolmoryeo-tang effectively reduces panic attack frequency and intensity as adjunctive treatment for panic disorder.

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