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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Cohort Study Men's Health / Urology

Correlation Between Male Hormone Imbalance and Korean Medicine Pattern Types: A Prospective Cohort Study

이강민, 서준혁, 안소영, et al.

Journal of Korean Medicine (2023)

180 subjects Cohort Size
4 types Pattern Types
r=0.72 Correlation Coefficient

Korean medicine pattern types show significant correlation with pathological aspects of male hormone imbalance, and pattern-based customized treatment is effective for hormone recovery.

View Source 2023
Cohort Study Men's Health / Urology

Correlation Between Male Hormone Imbalance and Korean Medicine Pattern Types: A Prospective Cohort Study

이강민, 서준혁, 안소영, et al. Journal of Korean Medicine (2023)
180 subjects Cohort Size
4 types Pattern Types
r=0.72 Correlation Coefficient

Summary

A prospective cohort study analyzing the correlation between hormone profiles and pattern types in 180 male hormone imbalance patients classified by pattern. Testosterone was lowest in the kidney yang deficiency type, and the cortisol/testosterone ratio was significantly higher in the liver qi stagnation type. Pattern-customized herbal prescriptions were effective for hormone normalization.

Key Conclusion

Korean medicine pattern types show significant correlation with pathological aspects of male hormone imbalance, and pattern-based customized treatment is effective for hormone recovery.

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Before-After Men's Health / Urology

Effect of Boyanghwano-tang on Hormone Recovery in Testosterone Deficiency: A Pre-Post Comparison Study

김우성, 장현준, 노태형, et al.

Andrologia (2024)

50.0% Testosterone Increase Rate
52 subjects Number of Subjects
12 weeks Treatment Period

Boyanghwano-tang is effective for restoring hormone levels to normal range in testosterone deficiency patients, and a mechanism through SHBG regulation is suggested.

View Source 2024
Before-After Men's Health / Urology

Effect of Boyanghwano-tang on Hormone Recovery in Testosterone Deficiency: A Pre-Post Comparison Study

김우성, 장현준, 노태형, et al. Andrologia (2024)
50.0% Testosterone Increase Rate
52 subjects Number of Subjects
12 weeks Treatment Period

Summary

A study analyzing hormone changes before and after 12 weeks of Boyanghwano-tang administration in 52 men with testosterone deficiency (total testosterone <3 ng/mL). Total testosterone increased from an average of 2.4 ng/mL to 3.6 ng/mL, and bioavailable testosterone also increased significantly along with SHBG level reduction.

Key Conclusion

Boyanghwano-tang is effective for restoring hormone levels to normal range in testosterone deficiency patients, and a mechanism through SHBG regulation is suggested.

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RCT Respiratory Conditions

Immune Modulation Effect of Okbyungpung-san in High-Risk Groups for Environmental Respiratory Diseases: A Randomized Controlled Trial

이서준, 김채원, 정승호, et al.

Phytotherapy Research (2023)

52% Infection frequency reduction
96 patients Study population
NK cell increase Immune indicator improvement

Okbyungpung-san can be utilized as a preventive herbal medicine that strengthens immune function and reduces infection frequency in high-risk groups for environmental respiratory diseases.

View Source 2023
RCT Respiratory Conditions

Immune Modulation Effect of Okbyungpung-san in High-Risk Groups for Environmental Respiratory Diseases: A Randomized Controlled Trial

이서준, 김채원, 정승호, et al. Phytotherapy Research (2023)
52% Infection frequency reduction
96 patients Study population
NK cell increase Immune indicator improvement

Summary

A comparison of Okbyungpung-san 12-week administration versus placebo in 96 residents of high air pollution exposure areas with history of recurrent upper respiratory infections. The Okbyungpung-san group showed 52% reduction in upper respiratory infection occurrence, with significant increases in NK cell activity and secretory IgA levels.

Key Conclusion

Okbyungpung-san can be utilized as a preventive herbal medicine that strengthens immune function and reduces infection frequency in high-risk groups for environmental respiratory diseases.

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Systematic Review Respiratory Conditions

Protective Effect of Cheongpyesagan-tang on Respiratory Inflammation from Particulate Matter Exposure: A Systematic Review

박준서, 김유나, 이도경, et al.

Environmental Health and Preventive Medicine (2024)

10 studies Analyzed studies
35% Symptom occurrence reduction
PM2.5 Main pollutant

Cheongpyesagan-tang shows preventive and therapeutic effects against respiratory inflammation from particulate matter and can be utilized for environmental respiratory disease management.

View Source 2024
Systematic Review Respiratory Conditions

Protective Effect of Cheongpyesagan-tang on Respiratory Inflammation from Particulate Matter Exposure: A Systematic Review

박준서, 김유나, 이도경, et al. Environmental Health and Preventive Medicine (2024)
10 studies Analyzed studies
35% Symptom occurrence reduction
PM2.5 Main pollutant

Summary

Ten preclinical and clinical studies evaluating the protective effect of Cheongpyesagan-tang on respiratory inflammatory response to particulate matter (PM2.5/PM10) exposure were systematically reviewed. In clinical studies, respiratory symptom occurrence rates in the herbal medicine group during high particulate matter concentration periods were significantly lower.

Key Conclusion

Cheongpyesagan-tang shows preventive and therapeutic effects against respiratory inflammation from particulate matter and can be utilized for environmental respiratory disease management.

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Before-After Respiratory Conditions

Effect of Combined Acupuncture and Moxibustion for Post-Pleurisy Chest Pain: A Pre-Post Comparison Study

김동혁, 조은솔, 이정현, et al.

대한침구의학회지 (2023)

62.3% Chest pain NRS reduction rate
42 patients Study population
6 weeks Treatment duration

Combined acupuncture and moxibustion can be utilized as an effective non-pharmacological management method for residual chest pain after pleurisy.

View Source 2023
Before-After Respiratory Conditions

Effect of Combined Acupuncture and Moxibustion for Post-Pleurisy Chest Pain: A Pre-Post Comparison Study

김동혁, 조은솔, 이정현, et al. 대한침구의학회지 (2023)
62.3% Chest pain NRS reduction rate
42 patients Study population
6 weeks Treatment duration

Summary

A pre-post comparison study performing acupuncture (LR14, LR13, LU1) and moxibustion for 6 weeks in 42 patients with residual chest pain persisting more than 4 weeks after pleurisy. Chest pain NRS decreased from 6.1 before treatment to 2.3 after treatment, with significantly alleviated deep breathing pain.

Key Conclusion

Combined acupuncture and moxibustion can be utilized as an effective non-pharmacological management method for residual chest pain after pleurisy.

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Narrative Review ENT Disorders

Recent Trends in Korean Medicine Treatment for Postnasal Drip Syndrome: A Narrative Review

이다현, 김상우, 박혜린, et al.

대한한의학회지 (2024)

18 studies Reviewed papers
8 prescriptions Major herbal prescriptions
5 years Review period

Korean medicine treatment for postnasal drip syndrome focuses on nasal secretion regulation and mucosal function recovery, with effective integrative approach.

View Source 2024
Narrative Review ENT Disorders

Recent Trends in Korean Medicine Treatment for Postnasal Drip Syndrome: A Narrative Review

이다현, 김상우, 박혜린, et al. 대한한의학회지 (2024)
18 studies Reviewed papers
8 prescriptions Major herbal prescriptions
5 years Review period

Summary

A narrative review comprehensively analyzing Korean medicine pathophysiological interpretation and treatment of postnasal drip syndrome. Clinical evidence for nasal prescriptions including Magnoliae flos and Xanthii fructus was analyzed, along with adjunctive effects of nasal irrigation and fumigation. A total of 18 related studies were reviewed.

Key Conclusion

Korean medicine treatment for postnasal drip syndrome focuses on nasal secretion regulation and mucosal function recovery, with effective integrative approach.

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Case Study ENT Disorders

Recurrence Prevention Effect of Korean Medicine Combination Treatment for Recurrent Tonsillitis: A Case Report

한서윤, 정우진, 김태리, et al.

한방안이비인후피부과학회지 (2023)

73% Recurrence reduction rate
9 patients Number of cases
6 months Treatment duration

Korean medicine combination treatment markedly reduces recurrence rate in recurrent tonsillitis patients and may serve as an alternative to surgical treatment.

View Source 2023
Case Study ENT Disorders

Recurrence Prevention Effect of Korean Medicine Combination Treatment for Recurrent Tonsillitis: A Case Report

한서윤, 정우진, 김태리, et al. 한방안이비인후피부과학회지 (2023)
73% Recurrence reduction rate
9 patients Number of cases
6 months Treatment duration

Summary

A case report performing herbal medicine (modified Bangpungtongseong-san), acupuncture, and pharmacopuncture for 6 months in 9 patients with recurrent tonsillitis (4 or more times annually). Tonsillitis recurrence decreased by an average of 73% during treatment period, with improvements in tonsillar hypertrophy grade.

Key Conclusion

Korean medicine combination treatment markedly reduces recurrence rate in recurrent tonsillitis patients and may serve as an alternative to surgical treatment.

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RCT Respiratory Conditions

Effect of Acupuncture for Patients with Anxiety Disorder Accompanied by Dyspnea: A Randomized Controlled Trial

김하은, 정민규, 이승아, et al.

Journal of Acupuncture and Meridian Studies (2023)

1.4 points mMRC scale improvement
76 patients Study population
48% BAI score reduction

Acupuncture is an effective non-pharmacological treatment that simultaneously improves both symptoms in patients with comorbid dyspnea and anxiety.

View Source 2023
RCT Respiratory Conditions

Effect of Acupuncture for Patients with Anxiety Disorder Accompanied by Dyspnea: A Randomized Controlled Trial

김하은, 정민규, 이승아, et al. Journal of Acupuncture and Meridian Studies (2023)
1.4 points mMRC scale improvement
76 patients Study population
48% BAI score reduction

Summary

A randomized controlled trial comparing acupuncture at PC6, HT7, BL13 versus sham acupuncture in 76 patients with comorbid dyspnea and anxiety disorder. After 6 weeks, the acupuncture group showed significantly improved mMRC dyspnea scale, with concurrent reduction in BAI (anxiety scale).

Key Conclusion

Acupuncture is an effective non-pharmacological treatment that simultaneously improves both symptoms in patients with comorbid dyspnea and anxiety.

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Cohort Study Respiratory Conditions

Safety and Efficacy of Long-Term Bopye-tang Administration in Elderly with Reduced Pulmonary Function: A Cohort Study

조수현, 김영진, 박지수, et al.

대한한방내과학회지 (2024)

8.7% FEV1 improvement
88 patients Study population
24 weeks Treatment duration

Long-term Bopye-tang administration is a safe Korean medicine treatment that slows the progression of reduced pulmonary function in the elderly and improves systemic physical strength.

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Cohort Study Respiratory Conditions

Safety and Efficacy of Long-Term Bopye-tang Administration in Elderly with Reduced Pulmonary Function: A Cohort Study

조수현, 김영진, 박지수, et al. 대한한방내과학회지 (2024)
8.7% FEV1 improvement
88 patients Study population
24 weeks Treatment duration

Summary

A prospective cohort study administering and observing Bopye-tang for 24 weeks in 88 elderly aged 65 or older with reduced pulmonary function (FEV1 predicted 60-80%). After treatment, FEV1 improved by an average of 8.7%, with reduced COPD acute exacerbations and improved overall physical strength indicators.

Key Conclusion

Long-term Bopye-tang administration is a safe Korean medicine treatment that slows the progression of reduced pulmonary function in the elderly and improves systemic physical strength.

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Cohort Study Mental Health

Cohort Study of Korean Medicine Treatment for Hypersomnia

Go GY, Suh JW, Nam DH, et al.

Sleep and Biological Rhythms (2023)

48% ESS Reduction
65 subjects Participants
8 weeks Treatment Period

Korean medicine treatment effectively improves daytime sleepiness in hypersomnia patients.

View Source 2023
Cohort Study Mental Health

Cohort Study of Korean Medicine Treatment for Hypersomnia

Go GY, Suh JW, Nam DH, et al. Sleep and Biological Rhythms (2023)
48% ESS Reduction
65 subjects Participants
8 weeks Treatment Period

Summary

Sixty-five hypersomnia patients were followed for 8 weeks, divided into herbal medicine (modified Bojungikgi-tang) + acupuncture treatment and waiting list groups. ESS daytime sleepiness scores decreased by 48% in the Korean medicine treatment group.

Key Conclusion

Korean medicine treatment effectively improves daytime sleepiness in hypersomnia patients.

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RCT Women's Health / Infertility

Randomized Double-Blind Trial of Gamisoyo-san for Menopausal Depression and Anxiety

Yoo JH, Ahn YJ, Kim DI, et al.

Menopause (2024)

44% Anxiety Reduction
38% Depression Reduction
Double-blind Study Design

Gamisoyo-san is an effective herbal treatment for menopausal depression and anxiety.

View Source 2024
RCT Women's Health / Infertility

Randomized Double-Blind Trial of Gamisoyo-san for Menopausal Depression and Anxiety

Yoo JH, Ahn YJ, Kim DI, et al. Menopause (2024)
44% Anxiety Reduction
38% Depression Reduction
Double-blind Study Design

Summary

One hundred women with menopausal depressive and anxiety symptoms were double-blind compared between Gamisoyo-san and placebo groups for 12 weeks. HADS anxiety (-44%) and depression (-38%) scores decreased significantly in the Gamisoyo-san group.

Key Conclusion

Gamisoyo-san is an effective herbal treatment for menopausal depression and anxiety.

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Narrative Review Mental Health

Effect of Combined Acupuncture Treatment and Psychological Counseling for Anger Control Disorder: A Narrative Review

Chung SH, Roh JD, Min BW, et al.

Aggression and Violent Behavior (2023)

18 sources Reviewed Literature
State anger↓ Main Effect
Combined treatment Treatment Strategy

The combination of acupuncture treatment and psychological counseling is useful for multidimensional treatment of anger control disorder.

View Source 2023
Narrative Review Mental Health

Effect of Combined Acupuncture Treatment and Psychological Counseling for Anger Control Disorder: A Narrative Review

Chung SH, Roh JD, Min BW, et al. Aggression and Violent Behavior (2023)
18 sources Reviewed Literature
State anger↓ Main Effect
Combined treatment Treatment Strategy

Summary

Eighteen articles on the effect of combined acupuncture treatment and psychological counseling for anger control disorder were reviewed. Combined treatment was effective for state anger reduction and anger expression regulation.

Key Conclusion

The combination of acupuncture treatment and psychological counseling is useful for multidimensional treatment of anger control disorder.

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