금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
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Total 1642 papers

RCT Mental Health

Serotonin Regulation Effect of Acupuncture Treatment in Depression Patients: A Randomized Controlled Trial

Kim SH, Park JY, Lee DH, et al.

Journal of Affective Disorders (2024)

52% HAM-D Reduction Rate
120 subjects Participants
8 weeks Treatment Period

Acupuncture treatment provides antidepressant effects by regulating serotonin metabolism in depression patients.

RCT Mental Health

Serotonin Regulation Effect of Acupuncture Treatment in Depression Patients: A Randomized Controlled Trial

Kim SH, Park JY, Lee DH, et al. Journal of Affective Disorders (2024)
52% HAM-D Reduction Rate
120 subjects Participants
8 weeks Treatment Period

Summary

One hundred twenty patients with major depressive disorder were compared between acupuncture and sham acupuncture groups for 8 weeks. HAM-D scores decreased by 52% and serum serotonin levels increased significantly in the acupuncture group.

Key Conclusion

Acupuncture treatment provides antidepressant effects by regulating serotonin metabolism in depression patients.

Meta-Analysis Respiratory Conditions

Effect of Combined Tai Chi and Doin Exercise in Pulmonary Rehabilitation for COPD Patients: A Meta-Analysis

이민호, 정세영, 김가람, et al.

COPD: Journal of Chronic Obstructive Pulmonary Disease (2023)

42.7 m 6-min walk distance increase
12 studies Analyzed studies
1,048 patients Total study population

Combined Tai Chi and Doin exercise is effective for improving exercise capacity and quality of life in COPD patients and is recommended as complementary exercise to existing pulmonary rehabilitation programs.

Meta-Analysis Respiratory Conditions

Effect of Combined Tai Chi and Doin Exercise in Pulmonary Rehabilitation for COPD Patients: A Meta-Analysis

이민호, 정세영, 김가람, et al. COPD: Journal of Chronic Obstructive Pulmonary Disease (2023)
42.7 m 6-min walk distance increase
12 studies Analyzed studies
1,048 patients Total study population

Summary

A meta-analysis of 12 RCTs (total 1,048 patients) evaluating the effect of combined Tai Chi and Doin exercise in pulmonary rehabilitation programs for COPD patients. The combination group showed average 42.7 m increase in 6-minute walk distance, with significant improvement in COPD Assessment Test (CAT) scores.

Key Conclusion

Combined Tai Chi and Doin exercise is effective for improving exercise capacity and quality of life in COPD patients and is recommended as complementary exercise to existing pulmonary rehabilitation programs.

Systematic Review Respiratory Conditions

Korean Medicine Treatment Approach for Interstitial Lung Disease: A Systematic Review

박정우, 김시현, 이동건, et al.

Integrative Medicine Research (2024)

11 studies Analyzed studies
FVC 5.3% FVC decline mitigation
38% Dyspnea VAS improvement

Korean medicine treatment can play an adjunctive role in suppressing progression of interstitial lung disease and improving quality of life, but large-scale clinical trials are needed.

Systematic Review Respiratory Conditions

Korean Medicine Treatment Approach for Interstitial Lung Disease: A Systematic Review

박정우, 김시현, 이동건, et al. Integrative Medicine Research (2024)
11 studies Analyzed studies
FVC 5.3% FVC decline mitigation
38% Dyspnea VAS improvement

Summary

Eleven studies evaluating Korean medicine treatment efficacy for interstitial lung disease (ILD) were systematically reviewed. Effects of prescriptions such as Cheongpyebowon-tang and Jaeumganghwa-tang in slowing forced vital capacity (FVC) decline rate and alleviating dyspnea symptoms were reported.

Key Conclusion

Korean medicine treatment can play an adjunctive role in suppressing progression of interstitial lung disease and improving quality of life, but large-scale clinical trials are needed.

RCT Respiratory Conditions

Effects of Herbal Medicine Adjuvant Treatment in Pneumonia Recovery: A Randomized Controlled Trial

김성민, 이예진, 조한결, et al.

Chinese Journal of Integrative Medicine (2023)

4.2 days Recovery duration reduction
110 patients Study population
89% Shadow resolution rate

Adjunctive administration of modified Saengmaek-san promotes clinical recovery in pneumonia recovery phase patients and presents evidence for integrative medicine treatment.

RCT Respiratory Conditions

Effects of Herbal Medicine Adjuvant Treatment in Pneumonia Recovery: A Randomized Controlled Trial

김성민, 이예진, 조한결, et al. Chinese Journal of Integrative Medicine (2023)
4.2 days Recovery duration reduction
110 patients Study population
89% Shadow resolution rate

Summary

A study comparing addition of modified Saengmaek-san to standard antibiotic treatment versus standard treatment alone in 110 patients in the recovery phase of community-acquired pneumonia. The herbal medicine combination group showed average 4.2-day reduction in time to complete recovery, with significantly higher chest X-ray shadow resolution rate.

Key Conclusion

Adjunctive administration of modified Saengmaek-san promotes clinical recovery in pneumonia recovery phase patients and presents evidence for integrative medicine treatment.

Before-After ENT Disorders

Nasal Airway Patency Improvement Effect of Moxibustion for Allergic Rhinitis Patients with Nasal Obstruction as Chief Complaint

정현석, 박미래, 김우진, et al.

Moxibustion Research (2024)

38% Nasal resistance reduction
68 patients Study population
8 weeks Treatment duration

Moxibustion objectively improves nasal airway patency in allergic rhinitis patients and has high utility as a non-pharmacological adjunctive treatment.

Before-After ENT Disorders

Nasal Airway Patency Improvement Effect of Moxibustion for Allergic Rhinitis Patients with Nasal Obstruction as Chief Complaint

정현석, 박미래, 김우진, et al. Moxibustion Research (2024)
38% Nasal resistance reduction
68 patients Study population
8 weeks Treatment duration

Summary

A pre-post comparison study performing indirect moxibustion for 8 weeks at ST36 and LI4 in 68 allergic rhinitis patients with chief complaint of nasal obstruction. Total nasal airway resistance on rhinomanometry decreased by 38% compared to before treatment, with significantly improved subjective nasal obstruction VAS.

Key Conclusion

Moxibustion objectively improves nasal airway patency in allergic rhinitis patients and has high utility as a non-pharmacological adjunctive treatment.

Narrative Review Respiratory Conditions

Narrative Review on Korean Medicine Management of Pediatric Asthma: Treatment Strategies and Evidence

한가영, 이승재, 김도연, et al.

대한한방소아과학회지 (2023)

23 studies Reviewed papers
5 stages Management protocol
15 years Review period

The Korean medicine approach to pediatric asthma provides various treatment tools for symptom control and recurrence prevention, showing potential for integrative medicine management models.

Narrative Review Respiratory Conditions

Narrative Review on Korean Medicine Management of Pediatric Asthma: Treatment Strategies and Evidence

한가영, 이승재, 김도연, et al. 대한한방소아과학회지 (2023)
23 studies Reviewed papers
5 stages Management protocol
15 years Review period

Summary

A comprehensive narrative review of Korean medicine treatment strategies for pediatric asthma. Clinical evidence for herbal medicine treatment such as Mahaenggamseok-tang and Socheongryong-tang, and pediatric acupoint massage and moxibustion was organized, and a staged Korean medicine management protocol was proposed.

Key Conclusion

The Korean medicine approach to pediatric asthma provides various treatment tools for symptom control and recurrence prevention, showing potential for integrative medicine management models.

Case Study Respiratory Conditions

Expectorant Effect of Modified Ijin-tang for Cough with Sputum: A Case Series

오진수, 김하늘, 정민서, et al.

한방재활의학과학회지 (2024)

65% Sputum output reduction
11 patients Number of cases
82% Sputum characteristic improvement rate

Modified Ijin-tang is an effective herbal medicine prescription for sputum volume reduction and characteristic improvement in damp-phlegm-type cough patients.

Case Study Respiratory Conditions

Expectorant Effect of Modified Ijin-tang for Cough with Sputum: A Case Series

오진수, 김하늘, 정민서, et al. 한방재활의학과학회지 (2024)
65% Sputum output reduction
11 patients Number of cases
82% Sputum characteristic improvement rate

Summary

A case series administering modified Ijin-tang for 4 weeks to 11 patients diagnosed with damp-phlegm-type cough. After treatment, daily sputum output decreased by average 65%, and sputum color changed from yellow to clear in 82% of patients. Cough frequency also concurrently decreased.

Key Conclusion

Modified Ijin-tang is an effective herbal medicine prescription for sputum volume reduction and characteristic improvement in damp-phlegm-type cough patients.

Systematic Review Respiratory Conditions

Systematic Review of Herbal Medicine Treatment for Chronic Bronchitis

이수빈, 김정호, 박선미, et al.

Journal of Integrative Medicine (2023)

14 studies Analyzed studies
1,056 patients Total study population
71% Average efficacy rate

Herbal medicine treatment is a promising treatment option for symptom management in chronic bronchitis, but methodological quality of research needs improvement.

Systematic Review Respiratory Conditions

Systematic Review of Herbal Medicine Treatment for Chronic Bronchitis

이수빈, 김정호, 박선미, et al. Journal of Integrative Medicine (2023)
14 studies Analyzed studies
1,056 patients Total study population
71% Average efficacy rate

Summary

Fourteen clinical studies evaluating the efficacy and safety of herbal medicine treatment for chronic bronchitis were systematically reviewed. Various prescriptions including Ijin-tang, Cheongpye-tang, and Samso-eum were used, with most studies reporting significant improvements in cough/sputum symptoms and pulmonary function indicators.

Key Conclusion

Herbal medicine treatment is a promising treatment option for symptom management in chronic bronchitis, but methodological quality of research needs improvement.

Before-After Respiratory Conditions

Antipyretic and Expectorant Effects of Eungyo-san for Acute Bronchitis: A Pre-Post Comparison Study

최준영, 한소희, 이민재, et al.

동의생리병리학회지 (2024)

1.8 days Fever duration reduction
58 patients Study population
63% Sputum viscosity reduction

Eungyo-san can be utilized as an effective antipyretic and expectorant for initial treatment of acute bronchitis and may contribute to reducing antibiotic prescription.

Before-After Respiratory Conditions

Antipyretic and Expectorant Effects of Eungyo-san for Acute Bronchitis: A Pre-Post Comparison Study

최준영, 한소희, 이민재, et al. 동의생리병리학회지 (2024)
1.8 days Fever duration reduction
58 patients Study population
63% Sputum viscosity reduction

Summary

A pre-post comparison study administering Eungyo-san for 7 days to 58 adult patients diagnosed with acute bronchitis. Fever duration was shortened by an average of 1.8 days compared to natural course in control literature, with significantly reduced sputum volume and viscosity.

Key Conclusion

Eungyo-san can be utilized as an effective antipyretic and expectorant for initial treatment of acute bronchitis and may contribute to reducing antibiotic prescription.

RCT ENT Disorders

Anti-Inflammatory Effect of Hyeonggaeyeongyo-tang for Acute Sinusitis: A Randomized Controlled Trial

김태완, 이서연, 박준혁, et al.

Evidence-Based Complementary and Alternative Medicine (2024)

78% Symptom improvement rate
92 patients Study population
2 weeks Treatment duration

Hyeonggaeyeongyo-tang shows efficacy equivalent to antibiotics for anti-inflammatory treatment of acute sinusitis and can be safely used without resistance concerns.

RCT ENT Disorders

Anti-Inflammatory Effect of Hyeonggaeyeongyo-tang for Acute Sinusitis: A Randomized Controlled Trial

김태완, 이서연, 박준혁, et al. Evidence-Based Complementary and Alternative Medicine (2024)
78% Symptom improvement rate
92 patients Study population
2 weeks Treatment duration

Summary

A randomized controlled trial comparing Hyeonggaeyeongyo-tang treatment versus antibiotic alone groups in 92 patients with acute sinusitis. After 2 weeks of treatment, the Hyeonggaeyeongyo-tang group showed significant improvements in sinus tenderness and purulent rhinorrhea, with decreased sinus opacity scores on CT.

Key Conclusion

Hyeonggaeyeongyo-tang shows efficacy equivalent to antibiotics for anti-inflammatory treatment of acute sinusitis and can be safely used without resistance concerns.

RCT Men's Health / Urology

Effect of Electroacupuncture Treatment on Ejaculation Latency Time Extension in Premature Ejaculation: A Randomized Controlled Trial

황석진, 나영준, 김현수, et al.

Journal of Acupuncture and Meridian Studies (2023)

3.6 fold IELT Extension Ratio
64 subjects Number of Subjects
p<0.001 Statistical Significance

Electroacupuncture treatment significantly extends ejaculation latency time in premature ejaculation patients and can be a safe alternative for patients concerned about drug side effects.

RCT Men's Health / Urology

Effect of Electroacupuncture Treatment on Ejaculation Latency Time Extension in Premature Ejaculation: A Randomized Controlled Trial

황석진, 나영준, 김현수, et al. Journal of Acupuncture and Meridian Studies (2023)
3.6 fold IELT Extension Ratio
64 subjects Number of Subjects
p<0.001 Statistical Significance

Summary

A randomized controlled trial evaluating the effect of electroacupuncture treatment in 64 men with premature ejaculation (IELT <2 minutes). After 8 weeks of electroacupuncture treatment at Hoeeum and Junggeuk acupoints, IELT significantly extended from an average of 1.3 minutes to 4.7 minutes, and PEDT scores also improved significantly.

Key Conclusion

Electroacupuncture treatment significantly extends ejaculation latency time in premature ejaculation patients and can be a safe alternative for patients concerned about drug side effects.

Narrative Review Men's Health / Urology

Recent Research Trends in Korean Medicine Treatment for Non-Bacterial Prostatitis: A Narrative Literature Review

조현우, 양승훈, 김지훈, et al.

Integrative Medicine Research (2024)

47 studies Analyzed Studies
10 years Analysis Period
78.7% Symptom Improvement Rate (Average)

Evidence for Korean medicine treatment of non-bacterial prostatitis is accumulating, and additional verification through multicenter randomized controlled trials is needed.

Narrative Review Men's Health / Urology

Recent Research Trends in Korean Medicine Treatment for Non-Bacterial Prostatitis: A Narrative Literature Review

조현우, 양승훈, 김지훈, et al. Integrative Medicine Research (2024)
47 studies Analyzed Studies
10 years Analysis Period
78.7% Symptom Improvement Rate (Average)

Summary

A narrative literature review analyzing research trends in Korean medicine treatment for non-bacterial prostatitis (NIH Category IIIB). Forty-seven studies published in the past 10 years were analyzed, and herbal medicine and acupuncture combination showed superior effects to single treatments. The evidence level of low-frequency electroacupuncture, pharmacopuncture, and moxibustion treatment was gradually improving.

Key Conclusion

Evidence for Korean medicine treatment of non-bacterial prostatitis is accumulating, and additional verification through multicenter randomized controlled trials is needed.