금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
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Total 1642 papers

Before-After Pediatric / Adolescent Care

Pre-Post Study of Skin Barrier Function Changes in Infants with Atopic Eczema After Korean Medicine Treatment

Kim MJ, Park SY, et al.

대한한방소아과학회지 (2023)

35.7% TEWL reduction rate
28.4% Skin hydration increase
8 weeks Treatment duration

After 8 weeks of combined herbal bathing therapy and oral medication, TEWL decreased by 35.7% and skin hydration increased by 28.4%, demonstrating significant improvement in skin barrier function.

Before-After Pediatric / Adolescent Care

Pre-Post Study of Skin Barrier Function Changes in Infants with Atopic Eczema After Korean Medicine Treatment

Kim MJ, Park SY, et al. 대한한방소아과학회지 (2023)
35.7% TEWL reduction rate
28.4% Skin hydration increase
8 weeks Treatment duration

Summary

A pre-post comparison study measuring transepidermal water loss (TEWL) and skin hydration changes before and after herbal bathing therapy and oral medication in 45 infants with infantile eczema.

Key Conclusion

After 8 weeks of combined herbal bathing therapy and oral medication, TEWL decreased by 35.7% and skin hydration increased by 28.4%, demonstrating significant improvement in skin barrier function.

Case Study Pediatric / Adolescent Care

Case Report of 7 Pediatric Asthma Cases with Combined Herbal Medicine and Moxibustion Treatment

Shin HK, Lee SR, et al.

대한한방내과학회지 (2024)

71.4% Attack frequency reduction
FEV1 +12.8% Pulmonary function improvement
7 cases Number of cases

After combined herbal medicine and moxibustion treatment, asthma attack frequency decreased by an average of 71.4% and FEV1 improved by 12.8%, suggesting potential of Korean medicine adjunctive treatment for pediatric asthma.

Case Study Pediatric / Adolescent Care

Case Report of 7 Pediatric Asthma Cases with Combined Herbal Medicine and Moxibustion Treatment

Shin HK, Lee SR, et al. 대한한방내과학회지 (2024)
71.4% Attack frequency reduction
FEV1 +12.8% Pulmonary function improvement
7 cases Number of cases

Summary

A case report on 7 pediatric asthma patients treated with modified Socheongryong-tang and moxibustion at CV12 and BL13 acupoints. Asthma attack frequency, pulmonary function (FEV1), and quality of life changes were followed over 3 months.

Key Conclusion

After combined herbal medicine and moxibustion treatment, asthma attack frequency decreased by an average of 71.4% and FEV1 improved by 12.8%, suggesting potential of Korean medicine adjunctive treatment for pediatric asthma.

Narrative Review Pediatric / Adolescent Care

Recent Literature Review on Korean Medicine Treatment for Pediatric Allergic Rhinitis

Jung WC, Kim TH, et al.

대한한방안이비인후피부과학회지 (2023)

32 studies Analyzed studies
TNSS -38.5% Rhinitis symptom reduction
10 years Literature search period

Herbal medicine treatments such as Socheongryong-tang and Yeonggamganmisinhain-tang, along with acupuncture at LI20 and LI4, showed significant effects in improving pediatric rhinitis symptoms (TNSS), with gradually improving evidence levels.

Narrative Review Pediatric / Adolescent Care

Recent Literature Review on Korean Medicine Treatment for Pediatric Allergic Rhinitis

Jung WC, Kim TH, et al. 대한한방안이비인후피부과학회지 (2023)
32 studies Analyzed studies
TNSS -38.5% Rhinitis symptom reduction
10 years Literature search period

Summary

A comprehensive review of domestic and international literature from the past 10 years on Korean medicine treatment (herbal medicine, acupuncture, moxibustion, nasal irrigation) for pediatric allergic rhinitis. A total of 32 studies were analyzed.

Key Conclusion

Herbal medicine treatments such as Socheongryong-tang and Yeonggamganmisinhain-tang, along with acupuncture at LI20 and LI4, showed significant effects in improving pediatric rhinitis symptoms (TNSS), with gradually improving evidence levels.

Systematic Review Pediatric / Adolescent Care

Systematic Review and Meta-Analysis of Modified Sagunja-tang for Pediatric Indigestion

Han SJ, Cho BH, et al.

대한한방소아과학회지 (2024)

91.2% Treatment efficacy rate
11 RCTs Included RCTs
OR 3.24 Treatment effect size

Modified Sagunja-tang improved treatment efficacy rates up to 91.2% for pediatric functional dyspepsia and showed superior results compared to Western medicine controls in alleviating abdominal pain and bloating symptoms.

Systematic Review Pediatric / Adolescent Care

Systematic Review and Meta-Analysis of Modified Sagunja-tang for Pediatric Indigestion

Han SJ, Cho BH, et al. 대한한방소아과학회지 (2024)
91.2% Treatment efficacy rate
11 RCTs Included RCTs
OR 3.24 Treatment effect size

Summary

Treatment efficacy of modified Sagunja-tang was systematically analyzed in pediatric patients with functional dyspepsia. A meta-analysis was performed including 11 RCTs.

Key Conclusion

Modified Sagunja-tang improved treatment efficacy rates up to 91.2% for pediatric functional dyspepsia and showed superior results compared to Western medicine controls in alleviating abdominal pain and bloating symptoms.

Meta-Analysis Pediatric / Adolescent Care

Meta-Analysis of Combined Herbal Medicine and Auricular Acupuncture Treatment for Pediatric Anorexia

Lim JH, Kwon OS, et al.

한방재활의학과학회지 (2023)

34.6% Food intake increase rate
1.8 kg/3 months Weight gain
486 patients Analysis population

Combined herbal medicine and auricular acupuncture treatment increased daily food intake by an average of 34.6% in children with anorexia, with average weight gain of 1.8 kg over 3 months, showing significant effects compared to monotherapy.

Meta-Analysis Pediatric / Adolescent Care

Meta-Analysis of Combined Herbal Medicine and Auricular Acupuncture Treatment for Pediatric Anorexia

Lim JH, Kwon OS, et al. 한방재활의학과학회지 (2023)
34.6% Food intake increase rate
1.8 kg/3 months Weight gain
486 patients Analysis population

Summary

Data from 486 pediatric patients with chief complaints of anorexia were meta-analyzed. Appetite and weight changes from combined treatment with herbal medicine (modified Hyangsayukgunja-tang, Gwibi-tang) and auricular acupuncture (stomach point, spleen point) were analyzed.

Key Conclusion

Combined herbal medicine and auricular acupuncture treatment increased daily food intake by an average of 34.6% in children with anorexia, with average weight gain of 1.8 kg over 3 months, showing significant effects compared to monotherapy.

Before-After Neurological Disorders

Pre-Post Comparison Study of Acupuncture Treatment for Entrapment Neuropathy (Cubital Tunnel Syndrome)

Kim CH, Han SJ, Cho KH, et al.

Journal of Hand Surgery (2024)

18% Conduction velocity↑
52% Numbness↓
40 subjects Participants

Acupuncture treatment is effective for nerve conduction and symptom improvement in cubital tunnel syndrome.

Before-After Neurological Disorders

Pre-Post Comparison Study of Acupuncture Treatment for Entrapment Neuropathy (Cubital Tunnel Syndrome)

Kim CH, Han SJ, Cho KH, et al. Journal of Hand Surgery (2024)
18% Conduction velocity↑
52% Numbness↓
40 subjects Participants

Summary

Acupuncture treatment was administered for 8 weeks to 40 patients with cubital tunnel syndrome. Ulnar nerve conduction velocity improved by 18%, and numbness of little and ring fingers decreased by 52%.

Key Conclusion

Acupuncture treatment is effective for nerve conduction and symptom improvement in cubital tunnel syndrome.

Cross-Sectional Neurological Disorders

Cross-Sectional Analysis of Anti-Neuritis Effect of Pharmacopuncture (Bee Venom) for Neuralgia

Yoon HJ, Park MJ, Cho WS, et al.

Journal of Pain Research (2024)

130 subjects Participants
38% Pain↓
TNF-α↓ Anti-inflammation

Bee venom pharmacopuncture reduces pain in neuralgia through anti-inflammatory mechanisms.

Cross-Sectional Neurological Disorders

Cross-Sectional Analysis of Anti-Neuritis Effect of Pharmacopuncture (Bee Venom) for Neuralgia

Yoon HJ, Park MJ, Cho WS, et al. Journal of Pain Research (2024)
130 subjects Participants
38% Pain↓
TNF-α↓ Anti-inflammation

Summary

Pain and inflammatory markers were analyzed according to bee venom pharmacopuncture use in 130 patients with neuralgia. The bee venom user group showed significantly lower NRS (-38%) and serum TNF-α.

Key Conclusion

Bee venom pharmacopuncture reduces pain in neuralgia through anti-inflammatory mechanisms.

Narrative Review Mental Health

Narrative Review of Acupuncture Treatment for Post-Stroke Depression

Shin SM, Bae GE, Kim KW, et al.

Journal of Stroke and Cerebrovascular Diseases (2023)

20 sources Reviewed Literature
HAM-D↓ Depression Reduction
Antidepressants↓ Dose Reduction Effect

Acupuncture treatment is useful as an adjunctive treatment for post-stroke depression.

Narrative Review Mental Health

Narrative Review of Acupuncture Treatment for Post-Stroke Depression

Shin SM, Bae GE, Kim KW, et al. Journal of Stroke and Cerebrovascular Diseases (2023)
20 sources Reviewed Literature
HAM-D↓ Depression Reduction
Antidepressants↓ Dose Reduction Effect

Summary

Twenty articles on the effect of acupuncture treatment for post-stroke depression were reviewed. Acupuncture treatment showed effects on HAM-D reduction and antidepressant dose reduction.

Key Conclusion

Acupuncture treatment is useful as an adjunctive treatment for post-stroke depression.

RCT Neurological Disorders

Comparison of Botox and Acupuncture Treatment for Hemifacial Spasm: A Randomized Controlled Trial

Jung WS, Kim CH, Han SJ, et al.

Journal of Neurology, Neurosurgery & Psychiatry (2024)

Equivalent effect Spasm↓
60 subjects Participants
Expression preserved Advantage

Electroacupuncture is effective as a Botox alternative for hemifacial spasm and is favorable for expression preservation.

RCT Neurological Disorders

Comparison of Botox and Acupuncture Treatment for Hemifacial Spasm: A Randomized Controlled Trial

Jung WS, Kim CH, Han SJ, et al. Journal of Neurology, Neurosurgery & Psychiatry (2024)
Equivalent effect Spasm↓
60 subjects Participants
Expression preserved Advantage

Summary

Sixty patients with hemifacial spasm were compared between electroacupuncture and Botox groups for 12 weeks. Electroacupuncture was equivalent to Botox in spasm frequency reduction with superior preservation of natural facial expressions.

Key Conclusion

Electroacupuncture is effective as a Botox alternative for hemifacial spasm and is favorable for expression preservation.

Systematic Review Neurological Disorders

Systematic Review of Electroacupuncture for Nerve Regeneration After Peripheral Nerve Injury

Cho WS, Park EJ, Lee JY, et al.

Neural Plasticity (2023)

20 studies Analyzed Studies
NGF↑ Growth Factor
Axons↑ Nerve Regeneration

Electroacupuncture is an effective non-pharmacological treatment that promotes peripheral nerve regeneration.

Systematic Review Neurological Disorders

Systematic Review of Electroacupuncture for Nerve Regeneration After Peripheral Nerve Injury

Cho WS, Park EJ, Lee JY, et al. Neural Plasticity (2023)
20 studies Analyzed Studies
NGF↑ Growth Factor
Axons↑ Nerve Regeneration

Summary

Twenty studies evaluating the effect of electroacupuncture for regeneration after peripheral nerve injury were systematically reviewed. Electroacupuncture showed effects on nerve growth factor (NGF) increase and axonal regeneration promotion.

Key Conclusion

Electroacupuncture is an effective non-pharmacological treatment that promotes peripheral nerve regeneration.

Meta-Analysis Neurological Disorders

Brain Imaging-Based Mechanism of Acupuncture Treatment for Migraine: A Meta-Analysis

Lee SG, Kwak MA, Jung SY, et al.

Pain (2024)

14 studies Analyzed Studies
Trigeminal nucleus↓ Hyperactivity Suppression
Pain inhibition↑ Descending Regulation

Acupuncture treatment regulates the central pain processing network of migraine.

Meta-Analysis Neurological Disorders

Brain Imaging-Based Mechanism of Acupuncture Treatment for Migraine: A Meta-Analysis

Lee SG, Kwak MA, Jung SY, et al. Pain (2024)
14 studies Analyzed Studies
Trigeminal nucleus↓ Hyperactivity Suppression
Pain inhibition↑ Descending Regulation

Summary

A meta-analysis of 14 brain imaging studies of acupuncture treatment for migraine. After acupuncture treatment, hyperactivity of the trigeminal nucleus and thalamus decreased, and the descending pain inhibition system was activated.

Key Conclusion

Acupuncture treatment regulates the central pain processing network of migraine.

Cross-Sectional Neurological Disorders

Cross-Sectional Analysis of Auricular Acupuncture for Tension Headache

Bae HS, Yoo SR, Cho AR, et al.

Headache (2024)

150 subjects Participants
32% Headache↓
40% Analgesics↓

Auricular acupuncture reduces headache frequency and analgesic dependence as a self-management tool for tension headache.

Cross-Sectional Neurological Disorders

Cross-Sectional Analysis of Auricular Acupuncture for Tension Headache

Bae HS, Yoo SR, Cho AR, et al. Headache (2024)
150 subjects Participants
32% Headache↓
40% Analgesics↓

Summary

Headache frequency and analgesic use were analyzed according to auricular acupuncture use in 150 patients with tension headache. The auricular acupuncture user group showed significantly fewer monthly headache days (-32%) and analgesic use (-40%).

Key Conclusion

Auricular acupuncture reduces headache frequency and analgesic dependence as a self-management tool for tension headache.