금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
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Total 1642 papers

Systematic Review Pediatric / Adolescent Care

Effect of Sihogayonggolmoryeo-tang for Pediatric Anxiety Disorder: A Systematic Review

Yang DS, Im SH, et al.

대한한방신경정신과학회지 (2024)

41.3% SCARED reduction rate
9 studies Included studies
p<0.005 Statistical significance

Sihogayonggolmoryeo-tang reduced SCARED scores by an average of 41.3% in pediatric anxiety disorder, with particularly effective results in anxiety with comorbid sleep disturbance.

Systematic Review Pediatric / Adolescent Care

Effect of Sihogayonggolmoryeo-tang for Pediatric Anxiety Disorder: A Systematic Review

Yang DS, Im SH, et al. 대한한방신경정신과학회지 (2024)
41.3% SCARED reduction rate
9 studies Included studies
p<0.005 Statistical significance

Summary

A systematic review of Sihogayonggolmoryeo-tang treatment efficacy in pediatric anxiety disorder patients. Nine studies were analyzed with SCARED and STAI-C score changes as primary outcome variables.

Key Conclusion

Sihogayonggolmoryeo-tang reduced SCARED scores by an average of 41.3% in pediatric anxiety disorder, with particularly effective results in anxiety with comorbid sleep disturbance.

Narrative Review Pediatric / Adolescent Care

Recent Literature Review on Korean Medicine Treatment for Tourette Syndrome in Children and Adolescents

Kang JE, Park MH, et al.

대한한방신경정신과학회지 (2023)

28 studies Reviewed studies
Effect size 0.72 Standardized mean difference
Adverse events 2.1% Adverse event incidence

Combination of herbal medicine (Cheonmagudeung-eum, modified Eokgan-san) and acupuncture treatment was most effective in alleviating Tourette syndrome symptoms, with fewer side effects than Western medication, making it suitable for long-term treatment.

Narrative Review Pediatric / Adolescent Care

Recent Literature Review on Korean Medicine Treatment for Tourette Syndrome in Children and Adolescents

Kang JE, Park MH, et al. 대한한방신경정신과학회지 (2023)
28 studies Reviewed studies
Effect size 0.72 Standardized mean difference
Adverse events 2.1% Adverse event incidence

Summary

A comprehensive review of 28 domestic and international studies on Korean medicine treatment (herbal medicine, acupuncture, moxibustion, qigong) for Tourette syndrome in children and adolescents. Effect sizes and safety were compared by treatment modality.

Key Conclusion

Combination of herbal medicine (Cheonmagudeung-eum, modified Eokgan-san) and acupuncture treatment was most effective in alleviating Tourette syndrome symptoms, with fewer side effects than Western medication, making it suitable for long-term treatment.

Case Study Pediatric / Adolescent Care

Case Report of 12 Children with Tic Disorder Treated with Korean Medicine: Modified Eokgan-san-Gajinpibanha

Moon HY, Cho DH, et al.

대한한방소아과학회지 (2024)

44.7% YGTSS reduction rate
12 cases Number of cases
16 weeks Follow-up period

After combined herbal medicine and acupuncture treatment, total YGTSS scores decreased by an average of 44.7%, with greater improvement in motor tics than vocal tics. No adverse effects were observed in any of the 12 cases.

Case Study Pediatric / Adolescent Care

Case Report of 12 Children with Tic Disorder Treated with Korean Medicine: Modified Eokgan-san-Gajinpibanha

Moon HY, Cho DH, et al. 대한한방소아과학회지 (2024)
44.7% YGTSS reduction rate
12 cases Number of cases
16 weeks Follow-up period

Summary

A report on 12 children with tic disorder treated with Eokgan-san-Gajinpibanha and acupuncture (GV20, GB20, LI4). YGTSS scores and tic frequency changes were followed over 16 weeks.

Key Conclusion

After combined herbal medicine and acupuncture treatment, total YGTSS scores decreased by an average of 44.7%, with greater improvement in motor tics than vocal tics. No adverse effects were observed in any of the 12 cases.

Before-After Pediatric / Adolescent Care

Pre-Post Comparison Study of Combined Herbal Medicine and Pediatric Acupuncture for Children with ADHD

Ryu GH, Jang SB, et al.

대한한방신경정신과학회지 (2023)

38.4% K-ARS score reduction
64 patients Study population
12 weeks Treatment duration

After 12 weeks of combined herbal medicine and pediatric acupuncture treatment, K-ARS scores decreased by an average of 38.4% and attention duration significantly increased, confirming the potential as adjunctive treatment for ADHD.

Before-After Pediatric / Adolescent Care

Pre-Post Comparison Study of Combined Herbal Medicine and Pediatric Acupuncture for Children with ADHD

Ryu GH, Jang SB, et al. 대한한방신경정신과학회지 (2023)
38.4% K-ARS score reduction
64 patients Study population
12 weeks Treatment duration

Summary

Pre- and post-treatment K-ARS scores, attention tests, and parent-reported behavioral scales were analyzed in 64 children diagnosed with ADHD who received combined modified Eokgan-san and pediatric acupuncture (Sasinchong, GV20).

Key Conclusion

After 12 weeks of combined herbal medicine and pediatric acupuncture treatment, K-ARS scores decreased by an average of 38.4% and attention duration significantly increased, confirming the potential as adjunctive treatment for ADHD.

Cross-Sectional Pediatric / Adolescent Care

Cross-Sectional Analysis of Modified Gwibi-tang Treatment for Children with Night Terrors

Seo EJ, Nam CH, et al.

대한한방신경정신과학회지 (2024)

83.6% Symptom improvement rate
18.2% Sleep efficiency improvement
128 patients Analysis population

Of children with night terrors who received modified Gwibi-tang treatment, 83.6% showed significant reduction in night terror occurrence, and sleep efficiency improved by an average of 18.2%.

Cross-Sectional Pediatric / Adolescent Care

Cross-Sectional Analysis of Modified Gwibi-tang Treatment for Children with Night Terrors

Seo EJ, Nam CH, et al. 대한한방신경정신과학회지 (2024)
83.6% Symptom improvement rate
18.2% Sleep efficiency improvement
128 patients Analysis population

Summary

A cross-sectional analysis of Korean medicine clinic records from 128 pediatric patients with night terrors. Night terror occurrence frequency and sleep efficiency changes after modified Gwibi-tang administration were investigated.

Key Conclusion

Of children with night terrors who received modified Gwibi-tang treatment, 83.6% showed significant reduction in night terror occurrence, and sleep efficiency improved by an average of 18.2%.

Cohort Study Pediatric / Adolescent Care

Cohort Study on Effects of Korean Medicine Treatment for Pediatric Enuresis: Modified Chukcheon-hwan and Moxibustion Combination

Oh JM, Kim YR, et al.

대한한방내과학회지 (2023)

75% Enuresis frequency reduction
156 patients Study population
12 weeks Treatment duration

After 12 weeks of combined herbal medicine and moxibustion treatment, enuresis frequency decreased from 5.2 to 1.3 episodes per week and functional bladder capacity significantly increased, confirming treatment efficacy.

Cohort Study Pediatric / Adolescent Care

Cohort Study on Effects of Korean Medicine Treatment for Pediatric Enuresis: Modified Chukcheon-hwan and Moxibustion Combination

Oh JM, Kim YR, et al. 대한한방내과학회지 (2023)
75% Enuresis frequency reduction
156 patients Study population
12 weeks Treatment duration

Summary

A cohort study with combined modified Chukcheon-hwan and moxibustion at CV4 in 156 children with enuresis. Enuresis frequency, bladder capacity, and sleep quality were followed over 12 weeks.

Key Conclusion

After 12 weeks of combined herbal medicine and moxibustion treatment, enuresis frequency decreased from 5.2 to 1.3 episodes per week and functional bladder capacity significantly increased, confirming treatment efficacy.

RCT Pediatric / Adolescent Care

Randomized Controlled Trial of Herbal Medicine for Pediatric Constipation: Focus on Modified Daesiho-tang

Baek YH, Song KJ, et al.

대한한방소아과학회지 (2024)

5.3/week Post-treatment bowel frequency
82 patients Study population
p<0.001 Statistical significance

Modified Daesiho-tang treatment increased weekly bowel frequency from 2.1 to 5.3 times in pediatric constipation patients, with significant effects compared to placebo also in stool form and abdominal pain improvement.

RCT Pediatric / Adolescent Care

Randomized Controlled Trial of Herbal Medicine for Pediatric Constipation: Focus on Modified Daesiho-tang

Baek YH, Song KJ, et al. 대한한방소아과학회지 (2024)
5.3/week Post-treatment bowel frequency
82 patients Study population
p<0.001 Statistical significance

Summary

An RCT comparing a modified Daesiho-tang group with a placebo group in 82 pediatric patients with functional constipation. Bowel frequency, Bristol stool scale, and abdominal pain scores were evaluated over 8 weeks.

Key Conclusion

Modified Daesiho-tang treatment increased weekly bowel frequency from 2.1 to 5.3 times in pediatric constipation patients, with significant effects compared to placebo also in stool form and abdominal pain improvement.

Meta-Analysis Pediatric / Adolescent Care

Meta-Analysis of Combined Herbal Medicine and Auricular Acupuncture Treatment for Pediatric Anorexia

Lim JH, Kwon OS, et al.

한방재활의학과학회지 (2023)

34.6% Food intake increase rate
1.8 kg/3 months Weight gain
486 patients Analysis population

Combined herbal medicine and auricular acupuncture treatment increased daily food intake by an average of 34.6% in children with anorexia, with average weight gain of 1.8 kg over 3 months, showing significant effects compared to monotherapy.

Meta-Analysis Pediatric / Adolescent Care

Meta-Analysis of Combined Herbal Medicine and Auricular Acupuncture Treatment for Pediatric Anorexia

Lim JH, Kwon OS, et al. 한방재활의학과학회지 (2023)
34.6% Food intake increase rate
1.8 kg/3 months Weight gain
486 patients Analysis population

Summary

Data from 486 pediatric patients with chief complaints of anorexia were meta-analyzed. Appetite and weight changes from combined treatment with herbal medicine (modified Hyangsayukgunja-tang, Gwibi-tang) and auricular acupuncture (stomach point, spleen point) were analyzed.

Key Conclusion

Combined herbal medicine and auricular acupuncture treatment increased daily food intake by an average of 34.6% in children with anorexia, with average weight gain of 1.8 kg over 3 months, showing significant effects compared to monotherapy.

Systematic Review Pediatric / Adolescent Care

Systematic Review and Meta-Analysis of Modified Sagunja-tang for Pediatric Indigestion

Han SJ, Cho BH, et al.

대한한방소아과학회지 (2024)

91.2% Treatment efficacy rate
11 RCTs Included RCTs
OR 3.24 Treatment effect size

Modified Sagunja-tang improved treatment efficacy rates up to 91.2% for pediatric functional dyspepsia and showed superior results compared to Western medicine controls in alleviating abdominal pain and bloating symptoms.

Systematic Review Pediatric / Adolescent Care

Systematic Review and Meta-Analysis of Modified Sagunja-tang for Pediatric Indigestion

Han SJ, Cho BH, et al. 대한한방소아과학회지 (2024)
91.2% Treatment efficacy rate
11 RCTs Included RCTs
OR 3.24 Treatment effect size

Summary

Treatment efficacy of modified Sagunja-tang was systematically analyzed in pediatric patients with functional dyspepsia. A meta-analysis was performed including 11 RCTs.

Key Conclusion

Modified Sagunja-tang improved treatment efficacy rates up to 91.2% for pediatric functional dyspepsia and showed superior results compared to Western medicine controls in alleviating abdominal pain and bloating symptoms.

Narrative Review Pediatric / Adolescent Care

Recent Literature Review on Korean Medicine Treatment for Pediatric Allergic Rhinitis

Jung WC, Kim TH, et al.

대한한방안이비인후피부과학회지 (2023)

32 studies Analyzed studies
TNSS -38.5% Rhinitis symptom reduction
10 years Literature search period

Herbal medicine treatments such as Socheongryong-tang and Yeonggamganmisinhain-tang, along with acupuncture at LI20 and LI4, showed significant effects in improving pediatric rhinitis symptoms (TNSS), with gradually improving evidence levels.

Narrative Review Pediatric / Adolescent Care

Recent Literature Review on Korean Medicine Treatment for Pediatric Allergic Rhinitis

Jung WC, Kim TH, et al. 대한한방안이비인후피부과학회지 (2023)
32 studies Analyzed studies
TNSS -38.5% Rhinitis symptom reduction
10 years Literature search period

Summary

A comprehensive review of domestic and international literature from the past 10 years on Korean medicine treatment (herbal medicine, acupuncture, moxibustion, nasal irrigation) for pediatric allergic rhinitis. A total of 32 studies were analyzed.

Key Conclusion

Herbal medicine treatments such as Socheongryong-tang and Yeonggamganmisinhain-tang, along with acupuncture at LI20 and LI4, showed significant effects in improving pediatric rhinitis symptoms (TNSS), with gradually improving evidence levels.

Case Study Pediatric / Adolescent Care

Case Report of 7 Pediatric Asthma Cases with Combined Herbal Medicine and Moxibustion Treatment

Shin HK, Lee SR, et al.

대한한방내과학회지 (2024)

71.4% Attack frequency reduction
FEV1 +12.8% Pulmonary function improvement
7 cases Number of cases

After combined herbal medicine and moxibustion treatment, asthma attack frequency decreased by an average of 71.4% and FEV1 improved by 12.8%, suggesting potential of Korean medicine adjunctive treatment for pediatric asthma.

Case Study Pediatric / Adolescent Care

Case Report of 7 Pediatric Asthma Cases with Combined Herbal Medicine and Moxibustion Treatment

Shin HK, Lee SR, et al. 대한한방내과학회지 (2024)
71.4% Attack frequency reduction
FEV1 +12.8% Pulmonary function improvement
7 cases Number of cases

Summary

A case report on 7 pediatric asthma patients treated with modified Socheongryong-tang and moxibustion at CV12 and BL13 acupoints. Asthma attack frequency, pulmonary function (FEV1), and quality of life changes were followed over 3 months.

Key Conclusion

After combined herbal medicine and moxibustion treatment, asthma attack frequency decreased by an average of 71.4% and FEV1 improved by 12.8%, suggesting potential of Korean medicine adjunctive treatment for pediatric asthma.

Before-After Pediatric / Adolescent Care

Pre-Post Study of Skin Barrier Function Changes in Infants with Atopic Eczema After Korean Medicine Treatment

Kim MJ, Park SY, et al.

대한한방소아과학회지 (2023)

35.7% TEWL reduction rate
28.4% Skin hydration increase
8 weeks Treatment duration

After 8 weeks of combined herbal bathing therapy and oral medication, TEWL decreased by 35.7% and skin hydration increased by 28.4%, demonstrating significant improvement in skin barrier function.

Before-After Pediatric / Adolescent Care

Pre-Post Study of Skin Barrier Function Changes in Infants with Atopic Eczema After Korean Medicine Treatment

Kim MJ, Park SY, et al. 대한한방소아과학회지 (2023)
35.7% TEWL reduction rate
28.4% Skin hydration increase
8 weeks Treatment duration

Summary

A pre-post comparison study measuring transepidermal water loss (TEWL) and skin hydration changes before and after herbal bathing therapy and oral medication in 45 infants with infantile eczema.

Key Conclusion

After 8 weeks of combined herbal bathing therapy and oral medication, TEWL decreased by 35.7% and skin hydration increased by 28.4%, demonstrating significant improvement in skin barrier function.