금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
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Total 1642 papers

Cross-Sectional Pediatric Traffic Accident

Korean Medicine Early Intervention for Developmental Delay Risk Group in Children After Traffic Accidents: A Cross-Sectional Analysis

Woo HS, Ahn YC, Son CG, et al.

Journal of Korean Medicine (2024)

86% Normal development maintenance rate
90 patients Participants

Korean medicine early intervention is effective for preventing developmental delay in children after traffic accidents.

Cross-Sectional Pediatric Traffic Accident

Korean Medicine Early Intervention for Developmental Delay Risk Group in Children After Traffic Accidents: A Cross-Sectional Analysis

Woo HS, Ahn YC, Son CG, et al. Journal of Korean Medicine (2024)
86% Normal development maintenance rate
90 patients Participants

Summary

A cross-sectional study analyzing developmental indicator differences according to Korean medicine early intervention in 90 pediatric patients at risk of developmental delay after traffic accidents. The early intervention group had significantly higher developmental assessment scores.

Key Conclusion

Korean medicine early intervention is effective for preventing developmental delay in children after traffic accidents.

Meta-Analysis Wellness / Restoration

Meta-Analysis of Telomere Length Changes with Korean Medicine Anti-Aging Treatment

Lee JA, Shin YC, Jang SB, et al.

BMC Complementary Medicine and Therapies (2023)

15% Telomere length preservation rate
780 patients Total participants

Korean medicine anti-aging treatment shows positive effects on maintaining telomere length, a cellular aging indicator.

Meta-Analysis Wellness / Restoration

Meta-Analysis of Telomere Length Changes with Korean Medicine Anti-Aging Treatment

Lee JA, Shin YC, Jang SB, et al. BMC Complementary Medicine and Therapies (2023)
15% Telomere length preservation rate
780 patients Total participants

Summary

A meta-analysis evaluating the effects of Korean medicine anti-aging treatment (herbal medicine, acupuncture, moxibustion) on telomere length. Analysis of 11 studies showed telomere length reduction was significantly suppressed in the Korean medicine treatment group.

Key Conclusion

Korean medicine anti-aging treatment shows positive effects on maintaining telomere length, a cellular aging indicator.

Case Study Wellness / Restoration

Korean Medicine Holistic Health Program Effect for Workplace Stress Management: A Case Series

Lee BH, Kang SY, Choi SM, et al.

Journal of Korean Medicine (2021)

56% Stress index reduction rate
10 patients Number of cases

Korean medicine holistic health program is useful for stress management and quality of life improvement in office workers.

Case Study Wellness / Restoration

Korean Medicine Holistic Health Program Effect for Workplace Stress Management: A Case Series

Lee BH, Kang SY, Choi SM, et al. Journal of Korean Medicine (2021)
56% Stress index reduction rate
10 patients Number of cases

Summary

A case series performing Korean medicine holistic health program including acupuncture, herbal medicine, and meditation for 4 weeks in 10 office workers. Improvements were observed in cortisol levels, stress index, and sleep quality.

Key Conclusion

Korean medicine holistic health program is useful for stress management and quality of life improvement in office workers.

Narrative Review Wellness / Restoration

Narrative Review on Antioxidant Effects of Herbal Tonifying Prescriptions

Song MY, Park JM, Lee GM, et al.

Journal of Ethnopharmacology (2022)

N/A Review study
38 studies Analyzed papers

Herbal tonifying prescriptions exert cellular protection and anti-aging effects through various antioxidant pathways.

Narrative Review Wellness / Restoration

Narrative Review on Antioxidant Effects of Herbal Tonifying Prescriptions

Song MY, Park JM, Lee GM, et al. Journal of Ethnopharmacology (2022)
N/A Review study
38 studies Analyzed papers

Summary

A narrative review on antioxidant mechanisms and effects of herbal tonifying prescriptions. Antioxidant activities and related research on major tonifying prescriptions including Sipjeondaebo-tang, Gyeongokgo, and Gongjin-dan were comprehensively organized.

Key Conclusion

Herbal tonifying prescriptions exert cellular protection and anti-aging effects through various antioxidant pathways.

Cross-Sectional Wellness / Restoration

Cold Prevention Effect of Korean Medicine Immunity Enhancement Program: A Cross-Sectional Survey Study

Ahn YC, Woo HS, Son CG, et al.

BMC Complementary Medicine and Therapies (2023)

38% Cold incidence reduction rate
800 patients Participants

Korean medicine immunity enhancement program is effective for cold prevention and has preventive medicine value.

Cross-Sectional Wellness / Restoration

Cold Prevention Effect of Korean Medicine Immunity Enhancement Program: A Cross-Sectional Survey Study

Ahn YC, Woo HS, Son CG, et al. BMC Complementary Medicine and Therapies (2023)
38% Cold incidence reduction rate
800 patients Participants

Summary

A cross-sectional survey study comparing cold incidence rates between 400 Korean medicine immunity enhancement program participants and 400 non-participants. The program participation group had significantly fewer cold incidence episodes over the past year.

Key Conclusion

Korean medicine immunity enhancement program is effective for cold prevention and has preventive medicine value.

RCT Gyeongokgo (瓊玉膏)

Cognitive Function and Anti-Aging Effects of Gyeongokgo: A Randomized Controlled Trial

Jung IC, Cho KH, Park SJ, et al.

Evidence-Based Complementary and Alternative Medicine (2024)

22% Cognitive function improvement rate
100 patients Participants

Gyeongokgo is an effective Korean medicine tonifying prescription for cognitive function maintenance and anti-aging in middle-aged and older adults.

RCT Gyeongokgo (瓊玉膏)

Cognitive Function and Anti-Aging Effects of Gyeongokgo: A Randomized Controlled Trial

Jung IC, Cho KH, Park SJ, et al. Evidence-Based Complementary and Alternative Medicine (2024)
22% Cognitive function improvement rate
100 patients Participants

Summary

A randomized controlled trial comparing Gyeongokgo and placebo for 12 weeks in 100 adults aged 55 and older. The Gyeongokgo group showed significant improvements in cognitive function tests (MMSE, MoCA) and oxidative stress indicators.

Key Conclusion

Gyeongokgo is an effective Korean medicine tonifying prescription for cognitive function maintenance and anti-aging in middle-aged and older adults.

Systematic Review Gongjindan (拱辰丹)

Systematic Review and Meta-Analysis of Chronic Fatigue and Immune Function Improvement with Gongjin-dan

Kwon CY, Lee SH, Kim AR, et al.

Journal of Ethnopharmacology (2023)

67% Fatigue reduction rate
920 patients Total participants

Gongjin-dan is an effective traditional tonifying prescription for chronic fatigue relief and immune function enhancement.

Systematic Review Gongjindan (拱辰丹)

Systematic Review and Meta-Analysis of Chronic Fatigue and Immune Function Improvement with Gongjin-dan

Kwon CY, Lee SH, Kim AR, et al. Journal of Ethnopharmacology (2023)
67% Fatigue reduction rate
920 patients Total participants

Summary

A systematic review and meta-analysis evaluating effects of Gongjin-dan on chronic fatigue and immune function improvement. Analysis of 14 studies showed significant fatigue reduction and immune indicator improvement in the Gongjin-dan administration group.

Key Conclusion

Gongjin-dan is an effective traditional tonifying prescription for chronic fatigue relief and immune function enhancement.

Cohort Study Private Inpatient Room

Impact of Korean Medicine Tonifying Treatment on Quality of Life in Cancer Patients: A Prospective Cohort Study

Shin BC, Ko SG, Lee MS, et al.

BMC Complementary Medicine and Therapies (2024)

45% Quality of life improvement rate
80 patients Participants

Korean medicine tonifying treatment contributes to quality of life improvement and overall health status improvement in cancer patients.

Cohort Study Private Inpatient Room

Impact of Korean Medicine Tonifying Treatment on Quality of Life in Cancer Patients: A Prospective Cohort Study

Shin BC, Ko SG, Lee MS, et al. BMC Complementary Medicine and Therapies (2024)
45% Quality of life improvement rate
80 patients Participants

Summary

A cohort study performing Korean medicine tonifying treatment (herbal medicine, acupuncture, moxibustion) for 6 months and tracking quality of life in 80 patients visiting Korean medicine clinics for tonification after cancer treatment. EORTC QLQ-C30 scores significantly improved.

Key Conclusion

Korean medicine tonifying treatment contributes to quality of life improvement and overall health status improvement in cancer patients.

Meta-Analysis Private Inpatient Room

Anticancer Adjuvant Effects and Immune Modulation Mechanism of Sipjeondaebo-tang: A Meta-Analysis

Lee MS, Shin BC, Ko SG, et al.

Journal of Ethnopharmacology (2022)

31% Side effect alleviation rate
1,120 patients Total participants

Sipjeondaebo-tang is an effective adjuvant therapy for alleviating side effects of anticancer treatment and reinforcing immune function.

Meta-Analysis Private Inpatient Room

Anticancer Adjuvant Effects and Immune Modulation Mechanism of Sipjeondaebo-tang: A Meta-Analysis

Lee MS, Shin BC, Ko SG, et al. Journal of Ethnopharmacology (2022)
31% Side effect alleviation rate
1,120 patients Total participants

Summary

A meta-analysis evaluating anticancer adjuvant effects and immune modulation mechanism of Sipjeondaebo-tang. Analysis of 16 clinical studies showed significant immune cell count increases and reduced anticancer treatment side effects in the Sipjeondaebo-tang combination group.

Key Conclusion

Sipjeondaebo-tang is an effective adjuvant therapy for alleviating side effects of anticancer treatment and reinforcing immune function.

Before-After Wellness / Restoration

Pre-Post Comparison Study of Combined Korean Medicine Exercise Therapy and Herbal Medicine for Physical Strength Enhancement in Middle-Aged and Older Adults

Min WK, Kim EJ, Lee SG, et al.

Journal of Korean Medicine (2023)

33% Physical strength indicator improvement rate
65 patients Participants

Combined Korean medicine exercise therapy and herbal medicine is an effective integrative health management method for physical strength enhancement in middle-aged and older adults.

Before-After Wellness / Restoration

Pre-Post Comparison Study of Combined Korean Medicine Exercise Therapy and Herbal Medicine for Physical Strength Enhancement in Middle-Aged and Older Adults

Min WK, Kim EJ, Lee SG, et al. Journal of Korean Medicine (2023)
33% Physical strength indicator improvement rate
65 patients Participants

Summary

Korean medicine exercise therapy (qigong, Doin) and physical strength enhancement herbal medicine were combined for 8 weeks in 65 middle-aged and older adults aged 50-70, with pre-post comparison. Physical strength indicators including grip strength, balance, and walking speed significantly improved.

Key Conclusion

Combined Korean medicine exercise therapy and herbal medicine is an effective integrative health management method for physical strength enhancement in middle-aged and older adults.

RCT Wellness / Restoration

Changes in Gut Microbiota Diversity with Korean Medicine Tonifying Treatment: A Randomized Controlled Trial

Yun MH, Lee JW, Kim HJ, et al.

BMC Complementary Medicine and Therapies (2025)

24% Microbial diversity increase
60 patients Participants

Tonifying herbal medicine contributes to overall health promotion by increasing gut microbiota diversity.

RCT Wellness / Restoration

Changes in Gut Microbiota Diversity with Korean Medicine Tonifying Treatment: A Randomized Controlled Trial

Yun MH, Lee JW, Kim HJ, et al. BMC Complementary Medicine and Therapies (2025)
24% Microbial diversity increase
60 patients Participants

Summary

A randomized controlled trial comparing tonifying herbal medicine and placebo for 8 weeks in 60 healthy adults. Gut microbiota analysis showed significant increases in beneficial bacteria ratio and microbial diversity in the tonifying herbal medicine group.

Key Conclusion

Tonifying herbal medicine contributes to overall health promotion by increasing gut microbiota diversity.

Cross-Sectional Wellness / Restoration

Analysis of Health-Related Quality of Life in Korean Medicine Tonifying Program Participants: A Cross-Sectional Study

Choi IH, Lee BH, Kim JI, et al.

Evidence-Based Complementary and Alternative Medicine (2022)

89% Good quality of life ratio
700 patients Participants

Korean medicine tonifying program participation is closely associated with improved health-related quality of life.

Cross-Sectional Wellness / Restoration

Analysis of Health-Related Quality of Life in Korean Medicine Tonifying Program Participants: A Cross-Sectional Study

Choi IH, Lee BH, Kim JI, et al. Evidence-Based Complementary and Alternative Medicine (2022)
89% Good quality of life ratio
700 patients Participants

Summary

A cross-sectional study comparing health-related quality of life between 350 adults participating in Korean medicine tonifying programs and 350 non-participants. The program participation group showed significantly higher scores in all subdomains of EQ-5D and SF-36.

Key Conclusion

Korean medicine tonifying program participation is closely associated with improved health-related quality of life.