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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
RCT Wellness / Restoration

Sleep Quality Improvement Effect of Korean Medicine Tonifying Treatment: A Randomized Controlled Trial

Moon SK, Ko CN, Jung WS, et al.

Pain Medicine (2023)

64% Sleep quality improvement rate
80 patients Participants

Tonifying herbal medicine treatment significantly improves sleep quality in chronic fatigue patients.

View Source 2023
RCT Wellness / Restoration

Sleep Quality Improvement Effect of Korean Medicine Tonifying Treatment: A Randomized Controlled Trial

Moon SK, Ko CN, Jung WS, et al. Pain Medicine (2023)
64% Sleep quality improvement rate
80 patients Participants

Summary

A randomized controlled trial comparing tonifying herbal medicine and placebo for 8 weeks in 80 chronic fatigue patients with comorbid sleep disturbance. Significant improvements appeared in PSQI scores, actigraphy sleep indicators, and daytime sleepiness scales.

Key Conclusion

Tonifying herbal medicine treatment significantly improves sleep quality in chronic fatigue patients.

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Systematic Review Wellness / Restoration

Systematic Review of Immunoglobulin Changes After Tonifying Medicine Administration

Kim AR, Kwon CY, Lee SH, et al.

BMC Complementary Medicine and Therapies (2024)

21% IgA increase rate
850 patients Total participants

Tonifying medicine significantly improves immunoglobulin levels and contributes to strengthening humoral immunity.

View Source 2024
Systematic Review Wellness / Restoration

Systematic Review of Immunoglobulin Changes After Tonifying Medicine Administration

Kim AR, Kwon CY, Lee SH, et al. BMC Complementary Medicine and Therapies (2024)
21% IgA increase rate
850 patients Total participants

Summary

A systematic review evaluating immunoglobulin (IgA, IgG, IgM) changes after tonifying medicine administration. Analysis of 13 studies showed significantly increased IgA and IgG levels in the tonifying medicine administration group.

Key Conclusion

Tonifying medicine significantly improves immunoglobulin levels and contributes to strengthening humoral immunity.

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Narrative Review Wellness / Restoration

Theoretical Foundation and Clinical Application of Korean Medicine Holistic Health Model: A Narrative Review

Ko SG, Shin BC, Lee MS, et al.

Journal of Ethnopharmacology (2021)

N/A Review study
42 studies Analyzed papers

The Korean medicine holistic health model can contribute to development of modern preventive medicine and integrative medicine.

View Source 2021
Narrative Review Wellness / Restoration

Theoretical Foundation and Clinical Application of Korean Medicine Holistic Health Model: A Narrative Review

Ko SG, Shin BC, Lee MS, et al. Journal of Ethnopharmacology (2021)
N/A Review study
42 studies Analyzed papers

Summary

Theoretical foundation of the Korean medicine holistic health model was narratively reviewed, and an integrative health management framework encompassing yangsaeng, tonification, and mental health was presented. Applicability from a modern preventive medicine perspective was discussed.

Key Conclusion

The Korean medicine holistic health model can contribute to development of modern preventive medicine and integrative medicine.

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Case Study Women's Health / Infertility

Effect of Tonifying Herbal Medicine Treatment for Menopausal Women: A Case Series

Ryu BH, Kim DI, Jeon JH, et al.

Journal of Korean Medicine (2020)

72% Menopausal symptom improvement rate
8 patients Number of cases

Customized tonifying herbal medicine treatment is effective for symptom relief and health maintenance in menopausal women.

View Source 2020
Case Study Women's Health / Infertility

Effect of Tonifying Herbal Medicine Treatment for Menopausal Women: A Case Series

Ryu BH, Kim DI, Jeon JH, et al. Journal of Korean Medicine (2020)
72% Menopausal symptom improvement rate
8 patients Number of cases

Summary

A case series administering customized tonifying herbal medicine for 12 weeks to 8 women complaining of menopausal symptoms. Improvements were observed in menopausal symptom scores, bone density, and blood estrogen levels.

Key Conclusion

Customized tonifying herbal medicine treatment is effective for symptom relief and health maintenance in menopausal women.

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Cross-Sectional Wellness / Restoration

Analysis of Health-Related Quality of Life in Korean Medicine Tonifying Program Participants: A Cross-Sectional Study

Choi IH, Lee BH, Kim JI, et al.

Evidence-Based Complementary and Alternative Medicine (2022)

89% Good quality of life ratio
700 patients Participants

Korean medicine tonifying program participation is closely associated with improved health-related quality of life.

View Source 2022
Cross-Sectional Wellness / Restoration

Analysis of Health-Related Quality of Life in Korean Medicine Tonifying Program Participants: A Cross-Sectional Study

Choi IH, Lee BH, Kim JI, et al. Evidence-Based Complementary and Alternative Medicine (2022)
89% Good quality of life ratio
700 patients Participants

Summary

A cross-sectional study comparing health-related quality of life between 350 adults participating in Korean medicine tonifying programs and 350 non-participants. The program participation group showed significantly higher scores in all subdomains of EQ-5D and SF-36.

Key Conclusion

Korean medicine tonifying program participation is closely associated with improved health-related quality of life.

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RCT Wellness / Restoration

Changes in Gut Microbiota Diversity with Korean Medicine Tonifying Treatment: A Randomized Controlled Trial

Yun MH, Lee JW, Kim HJ, et al.

BMC Complementary Medicine and Therapies (2025)

24% Microbial diversity increase
60 patients Participants

Tonifying herbal medicine contributes to overall health promotion by increasing gut microbiota diversity.

View Source 2025
RCT Wellness / Restoration

Changes in Gut Microbiota Diversity with Korean Medicine Tonifying Treatment: A Randomized Controlled Trial

Yun MH, Lee JW, Kim HJ, et al. BMC Complementary Medicine and Therapies (2025)
24% Microbial diversity increase
60 patients Participants

Summary

A randomized controlled trial comparing tonifying herbal medicine and placebo for 8 weeks in 60 healthy adults. Gut microbiota analysis showed significant increases in beneficial bacteria ratio and microbial diversity in the tonifying herbal medicine group.

Key Conclusion

Tonifying herbal medicine contributes to overall health promotion by increasing gut microbiota diversity.

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Before-After Wellness / Restoration

Pre-Post Comparison Study of Combined Korean Medicine Exercise Therapy and Herbal Medicine for Physical Strength Enhancement in Middle-Aged and Older Adults

Min WK, Kim EJ, Lee SG, et al.

Journal of Korean Medicine (2023)

33% Physical strength indicator improvement rate
65 patients Participants

Combined Korean medicine exercise therapy and herbal medicine is an effective integrative health management method for physical strength enhancement in middle-aged and older adults.

View Source 2023
Before-After Wellness / Restoration

Pre-Post Comparison Study of Combined Korean Medicine Exercise Therapy and Herbal Medicine for Physical Strength Enhancement in Middle-Aged and Older Adults

Min WK, Kim EJ, Lee SG, et al. Journal of Korean Medicine (2023)
33% Physical strength indicator improvement rate
65 patients Participants

Summary

Korean medicine exercise therapy (qigong, Doin) and physical strength enhancement herbal medicine were combined for 8 weeks in 65 middle-aged and older adults aged 50-70, with pre-post comparison. Physical strength indicators including grip strength, balance, and walking speed significantly improved.

Key Conclusion

Combined Korean medicine exercise therapy and herbal medicine is an effective integrative health management method for physical strength enhancement in middle-aged and older adults.

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Meta-Analysis Private Inpatient Room

Anticancer Adjuvant Effects and Immune Modulation Mechanism of Sipjeondaebo-tang: A Meta-Analysis

Lee MS, Shin BC, Ko SG, et al.

Journal of Ethnopharmacology (2022)

31% Side effect alleviation rate
1,120 patients Total participants

Sipjeondaebo-tang is an effective adjuvant therapy for alleviating side effects of anticancer treatment and reinforcing immune function.

View Source 2022
Meta-Analysis Private Inpatient Room

Anticancer Adjuvant Effects and Immune Modulation Mechanism of Sipjeondaebo-tang: A Meta-Analysis

Lee MS, Shin BC, Ko SG, et al. Journal of Ethnopharmacology (2022)
31% Side effect alleviation rate
1,120 patients Total participants

Summary

A meta-analysis evaluating anticancer adjuvant effects and immune modulation mechanism of Sipjeondaebo-tang. Analysis of 16 clinical studies showed significant immune cell count increases and reduced anticancer treatment side effects in the Sipjeondaebo-tang combination group.

Key Conclusion

Sipjeondaebo-tang is an effective adjuvant therapy for alleviating side effects of anticancer treatment and reinforcing immune function.

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Cohort Study Private Inpatient Room

Impact of Korean Medicine Tonifying Treatment on Quality of Life in Cancer Patients: A Prospective Cohort Study

Shin BC, Ko SG, Lee MS, et al.

BMC Complementary Medicine and Therapies (2024)

45% Quality of life improvement rate
80 patients Participants

Korean medicine tonifying treatment contributes to quality of life improvement and overall health status improvement in cancer patients.

View Source 2024
Cohort Study Private Inpatient Room

Impact of Korean Medicine Tonifying Treatment on Quality of Life in Cancer Patients: A Prospective Cohort Study

Shin BC, Ko SG, Lee MS, et al. BMC Complementary Medicine and Therapies (2024)
45% Quality of life improvement rate
80 patients Participants

Summary

A cohort study performing Korean medicine tonifying treatment (herbal medicine, acupuncture, moxibustion) for 6 months and tracking quality of life in 80 patients visiting Korean medicine clinics for tonification after cancer treatment. EORTC QLQ-C30 scores significantly improved.

Key Conclusion

Korean medicine tonifying treatment contributes to quality of life improvement and overall health status improvement in cancer patients.

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Systematic Review Gongjindan (拱辰丹)

Systematic Review and Meta-Analysis of Chronic Fatigue and Immune Function Improvement with Gongjin-dan

Kwon CY, Lee SH, Kim AR, et al.

Journal of Ethnopharmacology (2023)

67% Fatigue reduction rate
920 patients Total participants

Gongjin-dan is an effective traditional tonifying prescription for chronic fatigue relief and immune function enhancement.

View Source 2023
Systematic Review Gongjindan (拱辰丹)

Systematic Review and Meta-Analysis of Chronic Fatigue and Immune Function Improvement with Gongjin-dan

Kwon CY, Lee SH, Kim AR, et al. Journal of Ethnopharmacology (2023)
67% Fatigue reduction rate
920 patients Total participants

Summary

A systematic review and meta-analysis evaluating effects of Gongjin-dan on chronic fatigue and immune function improvement. Analysis of 14 studies showed significant fatigue reduction and immune indicator improvement in the Gongjin-dan administration group.

Key Conclusion

Gongjin-dan is an effective traditional tonifying prescription for chronic fatigue relief and immune function enhancement.

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RCT Gyeongokgo (瓊玉膏)

Cognitive Function and Anti-Aging Effects of Gyeongokgo: A Randomized Controlled Trial

Jung IC, Cho KH, Park SJ, et al.

Evidence-Based Complementary and Alternative Medicine (2024)

22% Cognitive function improvement rate
100 patients Participants

Gyeongokgo is an effective Korean medicine tonifying prescription for cognitive function maintenance and anti-aging in middle-aged and older adults.

View Source 2024
RCT Gyeongokgo (瓊玉膏)

Cognitive Function and Anti-Aging Effects of Gyeongokgo: A Randomized Controlled Trial

Jung IC, Cho KH, Park SJ, et al. Evidence-Based Complementary and Alternative Medicine (2024)
22% Cognitive function improvement rate
100 patients Participants

Summary

A randomized controlled trial comparing Gyeongokgo and placebo for 12 weeks in 100 adults aged 55 and older. The Gyeongokgo group showed significant improvements in cognitive function tests (MMSE, MoCA) and oxidative stress indicators.

Key Conclusion

Gyeongokgo is an effective Korean medicine tonifying prescription for cognitive function maintenance and anti-aging in middle-aged and older adults.

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Cross-Sectional Wellness / Restoration

Cold Prevention Effect of Korean Medicine Immunity Enhancement Program: A Cross-Sectional Survey Study

Ahn YC, Woo HS, Son CG, et al.

BMC Complementary Medicine and Therapies (2023)

38% Cold incidence reduction rate
800 patients Participants

Korean medicine immunity enhancement program is effective for cold prevention and has preventive medicine value.

View Source 2023
Cross-Sectional Wellness / Restoration

Cold Prevention Effect of Korean Medicine Immunity Enhancement Program: A Cross-Sectional Survey Study

Ahn YC, Woo HS, Son CG, et al. BMC Complementary Medicine and Therapies (2023)
38% Cold incidence reduction rate
800 patients Participants

Summary

A cross-sectional survey study comparing cold incidence rates between 400 Korean medicine immunity enhancement program participants and 400 non-participants. The program participation group had significantly fewer cold incidence episodes over the past year.

Key Conclusion

Korean medicine immunity enhancement program is effective for cold prevention and has preventive medicine value.

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