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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 92 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Cohort Study Women's Health / Infertility

Menstrual Cycle Normalization Effect of Modified Danggwijakyak-san for Women with Menstrual Irregularity: A Prospective Cohort Study

Yoon SE, Han KW, Lim JY, et al.

BMC Complementary Medicine and Therapies (2022)

82% Menstrual cycle normalization rate
95 patients Participants

Modified Danggwijakyak-san showed significant effects on menstrual cycle normalization in women with menstrual irregularity.

View Source 2022
Cohort Study Women's Health / Infertility

Menstrual Cycle Normalization Effect of Modified Danggwijakyak-san for Women with Menstrual Irregularity: A Prospective Cohort Study

Yoon SE, Han KW, Lim JY, et al. BMC Complementary Medicine and Therapies (2022)
82% Menstrual cycle normalization rate
95 patients Participants

Summary

A prospective cohort study administering modified Danggwijakyak-san for 12 weeks in 95 women complaining of menstrual irregularity. Changes in menstrual cycle regularity, menstrual flow, and accompanying symptoms were evaluated.

Key Conclusion

Modified Danggwijakyak-san showed significant effects on menstrual cycle normalization in women with menstrual irregularity.

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Meta-Analysis Women's Health / Infertility

Meta-Analysis of Ovulation Induction Effect of Korean Medicine Combination Therapy in PCOS Patients

Park MJ, Kim EH, Shin DS, et al.

Journal of Ethnopharmacology (2023)

71.5% Ovulation induction rate
2,134 patients Participants

Korean medicine combination therapy is effective for ovulation induction in PCOS patients and has high utility as a complementary approach to hormone therapy.

View Source 2023
Meta-Analysis Women's Health / Infertility

Meta-Analysis of Ovulation Induction Effect of Korean Medicine Combination Therapy in PCOS Patients

Park MJ, Kim EH, Shin DS, et al. Journal of Ethnopharmacology (2023)
71.5% Ovulation induction rate
2,134 patients Participants

Summary

Ovulation induction effects of herbal medicine, acupuncture, and moxibustion combination therapy were analyzed in PCOS patients. A total of 22 studies and over 2,100 patients' data were meta-analyzed. The combination therapy group showed significantly higher ovulation rates than controls.

Key Conclusion

Korean medicine combination therapy is effective for ovulation induction in PCOS patients and has high utility as a complementary approach to hormone therapy.

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RCT Women's Health / Infertility

Effect of Acupuncture on IVF Success Rates: A Randomized Controlled Trial

Lee JH, Choi YS, Yoon HJ, et al.

Fertility and Sterility (2024)

42.3% Implantation rate improvement
180 patients Participants

Combined acupuncture before and after IVF was confirmed to have significant effects on improving implantation rates.

View Source 2024
RCT Women's Health / Infertility

Effect of Acupuncture on IVF Success Rates: A Randomized Controlled Trial

Lee JH, Choi YS, Yoon HJ, et al. Fertility and Sterility (2024)
42.3% Implantation rate improvement
180 patients Participants

Summary

Acupuncture combination and control groups were compared in 180 infertile women undergoing IVF. Implantation rates and pregnancy maintenance rates were statistically significantly higher in the acupuncture group.

Key Conclusion

Combined acupuncture before and after IVF was confirmed to have significant effects on improving implantation rates.

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Systematic Review Women's Health / Infertility

Effect of Combined Herbal Medicine on Endometrial Receptivity in Infertile Women: A Systematic Review

Kim SH, Park JW, Lee MK, et al.

Evidence-Based Complementary and Alternative Medicine (2023)

78% Endometrial improvement rate
1,240 patients Participants

Combined herbal medicine can play a positive role in endometrial environment improvement in infertile women, with potential for combined treatment with assisted reproductive technology suggested.

View Source 2023
Systematic Review Women's Health / Infertility

Effect of Combined Herbal Medicine on Endometrial Receptivity in Infertile Women: A Systematic Review

Kim SH, Park JW, Lee MK, et al. Evidence-Based Complementary and Alternative Medicine (2023)
78% Endometrial improvement rate
1,240 patients Participants

Summary

Effects of combined herbal medicine on endometrial receptivity improvement in infertile women were systematically analyzed. A meta-analysis was performed including 18 RCTs. The combined herbal medicine group showed significant improvements in endometrial thickness and blood flow.

Key Conclusion

Combined herbal medicine can play a positive role in endometrial environment improvement in infertile women, with potential for combined treatment with assisted reproductive technology suggested.

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Case Study Women's Health / Infertility

Effect of Tonifying Herbal Medicine Treatment for Menopausal Women: A Case Series

Ryu BH, Kim DI, Jeon JH, et al.

Journal of Korean Medicine (2020)

72% Menopausal symptom improvement rate
8 patients Number of cases

Customized tonifying herbal medicine treatment is effective for symptom relief and health maintenance in menopausal women.

View Source 2020
Case Study Women's Health / Infertility

Effect of Tonifying Herbal Medicine Treatment for Menopausal Women: A Case Series

Ryu BH, Kim DI, Jeon JH, et al. Journal of Korean Medicine (2020)
72% Menopausal symptom improvement rate
8 patients Number of cases

Summary

A case series administering customized tonifying herbal medicine for 12 weeks to 8 women complaining of menopausal symptoms. Improvements were observed in menopausal symptom scores, bone density, and blood estrogen levels.

Key Conclusion

Customized tonifying herbal medicine treatment is effective for symptom relief and health maintenance in menopausal women.

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Cohort Study Women's Health / Infertility

Effect of Gamisoyo-san for Menopausal Syndrome: A Prospective Cohort Study

Chen HY, Lin YH, Wu JC, et al.

Menopause (2023)

54% Kupperman Index reduction
62% Hot flash reduction
156 patients Study population

Gamisoyo-san significantly improves vasomotor symptoms and emotional symptoms of menopausal syndrome and is a safe alternative to hormone replacement therapy.

View Source 2023
Cohort Study Women's Health / Infertility

Effect of Gamisoyo-san for Menopausal Syndrome: A Prospective Cohort Study

Chen HY, Lin YH, Wu JC, et al. Menopause (2023)
54% Kupperman Index reduction
62% Hot flash reduction
156 patients Study population

Summary

A cohort study comparing 12-week course between Gamisoyo-san administration and general management groups in 156 women with menopausal syndrome. The Gamisoyo-san group showed 54% reduction in KI (Kupperman Index), with particularly distinct effects on hot flashes (62% reduction) and insomnia (58% reduction).

Key Conclusion

Gamisoyo-san significantly improves vasomotor symptoms and emotional symptoms of menopausal syndrome and is a safe alternative to hormone replacement therapy.

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Meta-Analysis Women's Health / Infertility

Effect of Acupuncture for Dysmenorrhea: A Systematic Review and Meta-Analysis

Woo HL, Ji HR, Pak YK, et al.

Medicine (2022)

48% Analgesic use reduction
25 studies Analyzed studies
2,780 patients Total participants

Acupuncture is effective for dysmenorrhea pain relief and reduced analgesic dependence, and contributes to menstrual cycle normalization in long-term treatment.

View Source 2022
Meta-Analysis Women's Health / Infertility

Effect of Acupuncture for Dysmenorrhea: A Systematic Review and Meta-Analysis

Woo HL, Ji HR, Pak YK, et al. Medicine (2022)
48% Analgesic use reduction
25 studies Analyzed studies
2,780 patients Total participants

Summary

Twenty-five RCTs (total 2,780 patients) evaluating acupuncture effects for primary dysmenorrhea were meta-analyzed. The acupuncture group showed an average 11% additional reduction in VAS pain scores compared to NSAIDs group, with 48% reduction in analgesic use. Treatment for 3 months or more also significantly improved menstrual cycle normalization rates.

Key Conclusion

Acupuncture is effective for dysmenorrhea pain relief and reduced analgesic dependence, and contributes to menstrual cycle normalization in long-term treatment.

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RCT Women's Health / Infertility

Adjuvant Effect of Herbal Medicine Treatment for Female Infertility: A Randomized Controlled Trial

Ried K, Stuart K, et al.

Complementary Therapies in Medicine (2023)

48% Clinical pregnancy rate
2.1 mm Endometrial thickness increase
116 patients Study population

Combined herbal medicine treatment increases IVF success rates and contributes to improving implantation rates through endometrial environment improvement.

View Source 2023
RCT Women's Health / Infertility

Adjuvant Effect of Herbal Medicine Treatment for Female Infertility: A Randomized Controlled Trial

Ried K, Stuart K, et al. Complementary Therapies in Medicine (2023)
48% Clinical pregnancy rate
2.1 mm Endometrial thickness increase
116 patients Study population

Summary

A randomized controlled trial comparing herbal medicine combination and non-combination groups in 116 women with infertility undergoing IVF. The herbal medicine combination group showed clinical pregnancy rate of 48%, significantly higher than the non-combination group (31%). Endometrial thickness also increased by an average of 2.1 mm, confirming improved implantation environment.

Key Conclusion

Combined herbal medicine treatment increases IVF success rates and contributes to improving implantation rates through endometrial environment improvement.

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