금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
🔍

Total 92 papers

Before-After Women's Health / Infertility

Effect of Gwibi-tang for Menopausal Depression and Anxiety Symptoms: A Pre-Post Comparison Study

Im SJ, Ha YC, Noh KT, et al.

Journal of Korean Medicine (2023)

58% Depression symptom reduction rate
55 patients Participants

Gwibi-tang significantly reduced depression and anxiety symptoms in menopausal women and also contributed to quality of life improvement.

Before-After Women's Health / Infertility

Effect of Gwibi-tang for Menopausal Depression and Anxiety Symptoms: A Pre-Post Comparison Study

Im SJ, Ha YC, Noh KT, et al. Journal of Korean Medicine (2023)
58% Depression symptom reduction rate
55 patients Participants

Summary

Gwibi-tang was administered for 8 weeks to 55 women complaining of menopausal depression and anxiety symptoms. Pre- and post-treatment depression and anxiety levels were compared using PHQ-9 and GAD-7 scales.

Key Conclusion

Gwibi-tang significantly reduced depression and anxiety symptoms in menopausal women and also contributed to quality of life improvement.

Cross-Sectional Women's Health / Infertility

Korean Medicine Pattern Classification of PCOS and Treatment Response: A Cross-Sectional Analysis

Yoo MH, Kwon OS, Chae BY, et al.

Evidence-Based Complementary and Alternative Medicine (2022)

81% Tailored treatment response rate
320 patients Participants

Pattern type-tailored herbal medicine treatment significantly improved treatment response rates in PCOS patients.

Cross-Sectional Women's Health / Infertility

Korean Medicine Pattern Classification of PCOS and Treatment Response: A Cross-Sectional Analysis

Yoo MH, Kwon OS, Chae BY, et al. Evidence-Based Complementary and Alternative Medicine (2022)
81% Tailored treatment response rate
320 patients Participants

Summary

Korean medicine pattern classification was performed in 320 women diagnosed with PCOS, and herbal medicine treatment response by pattern type was analyzed. Treatment effects were compared by classifying into phlegm-damp, kidney deficiency, and qi stagnation-blood stasis types.

Key Conclusion

Pattern type-tailored herbal medicine treatment significantly improved treatment response rates in PCOS patients.

Meta-Analysis Women's Health / Infertility

Herbal Medicine Treatment for Sperm Quality Improvement in Male Spouses of Infertile Couples: A Meta-Analysis

Seo DW, Kim JB, Hong SH, et al.

BMC Complementary Medicine and Therapies (2024)

39% Sperm motility improvement
1,456 patients Participants

Herbal medicine treatment had significant effects on improving sperm motility and concentration in male infertility patients, and importance of joint couple treatment was confirmed.

Meta-Analysis Women's Health / Infertility

Herbal Medicine Treatment for Sperm Quality Improvement in Male Spouses of Infertile Couples: A Meta-Analysis

Seo DW, Kim JB, Hong SH, et al. BMC Complementary Medicine and Therapies (2024)
39% Sperm motility improvement
1,456 patients Participants

Summary

Sixteen studies administering herbal medicine to male spouses in couples with male infertility factors were meta-analyzed. Changes in sperm concentration, motility, and normal morphology rates were analyzed.

Key Conclusion

Herbal medicine treatment had significant effects on improving sperm motility and concentration in male infertility patients, and importance of joint couple treatment was confirmed.

RCT Women's Health / Infertility

Randomized Controlled Trial of Warm Needling Therapy for Dysmenorrhea Relief

Choi WJ, Bae EJ, Yim TK, et al.

Pain Medicine (2023)

72% Pain reduction rate
100 patients Participants

Warm needling therapy showed superior effects on dysmenorrhea relief compared to general acupuncture, with also significantly reduced analgesic use.

RCT Women's Health / Infertility

Randomized Controlled Trial of Warm Needling Therapy for Dysmenorrhea Relief

Choi WJ, Bae EJ, Yim TK, et al. Pain Medicine (2023)
72% Pain reduction rate
100 patients Participants

Summary

One hundred women with primary dysmenorrhea were compared between warm needling treatment and general acupuncture control groups. VAS pain scores, analgesic intake frequency, and menstruation-related quality of life scales were followed for 3 months.

Key Conclusion

Warm needling therapy showed superior effects on dysmenorrhea relief compared to general acupuncture, with also significantly reduced analgesic use.

Cohort Study Women's Health / Infertility

Long-Term Prognosis of Endometriosis Patients Receiving Korean Gynecology Treatment: A Retrospective Cohort Study

Kwon MJ, Heo JY, Jung WS, et al.

Journal of Ethnopharmacology (2021)

18% 5-year recurrence rate
180 patients Participants

Long-term recurrence rates of endometriosis patients receiving Korean gynecology treatment were low, with favorable pregnancy success rates.

Cohort Study Women's Health / Infertility

Long-Term Prognosis of Endometriosis Patients Receiving Korean Gynecology Treatment: A Retrospective Cohort Study

Kwon MJ, Heo JY, Jung WS, et al. Journal of Ethnopharmacology (2021)
18% 5-year recurrence rate
180 patients Participants

Summary

Five-year follow-up data of 180 women who received Korean gynecology treatment for endometriosis were analyzed. Recurrence rates, pregnancy success rates, and pain management satisfaction were evaluated.

Key Conclusion

Long-term recurrence rates of endometriosis patients receiving Korean gynecology treatment were low, with favorable pregnancy success rates.

Before-After Women's Health / Infertility

Effect of Vaginal Fumigation Therapy for Genitourinary Symptoms in Menopausal Women

Jang YH, Kim SB, Lee WD, et al.

Journal of Korean Medicine (2024)

64% Symptom improvement rate
45 patients Participants

Vaginal fumigation therapy showed significant effects on relieving genitourinary symptoms in menopausal women.

Before-After Women's Health / Infertility

Effect of Vaginal Fumigation Therapy for Genitourinary Symptoms in Menopausal Women

Jang YH, Kim SB, Lee WD, et al. Journal of Korean Medicine (2024)
64% Symptom improvement rate
45 patients Participants

Summary

Vaginal fumigation therapy was performed for 8 weeks in 45 women complaining of menopausal genitourinary symptoms (vaginal dryness, frequent urination, urinary incontinence). Pre- and post-treatment changes were compared through symptom evaluation scales and quality of life questionnaires.

Key Conclusion

Vaginal fumigation therapy showed significant effects on relieving genitourinary symptoms in menopausal women.

Narrative Review Women's Health / Infertility

Non-Surgical Korean Medicine Treatment Approach for Uterine Fibroids: A Narrative Literature Review

Son HK, Won SY, Baek JH, et al.

Evidence-Based Complementary and Alternative Medicine (2022)

22 studies Analyzed papers
4 types Treatment classifications

Korean medicine treatment provides various approaches for non-surgical management of uterine fibroids and has potential utility as conservative treatment before surgery.

Narrative Review Women's Health / Infertility

Non-Surgical Korean Medicine Treatment Approach for Uterine Fibroids: A Narrative Literature Review

Son HK, Won SY, Baek JH, et al. Evidence-Based Complementary and Alternative Medicine (2022)
22 studies Analyzed papers
4 types Treatment classifications

Summary

Korean medicine approaches for non-surgical treatment of uterine fibroids were narratively reviewed. Treatment methods including herbal medicine, acupuncture, moxibustion, and pharmacopuncture and recent clinical evidence were comprehensively organized.

Key Conclusion

Korean medicine treatment provides various approaches for non-surgical management of uterine fibroids and has potential utility as conservative treatment before surgery.

Case Study Women's Health / Infertility

Hormone Level Improvement Effect of Herbal Medicine Treatment in Women with Premature Ovarian Insufficiency: A Case Study

Oh JK, Yun HS, Chung EJ, et al.

BMC Complementary Medicine and Therapies (2023)

58% Hormone improvement rate
12 patients Participants

After herbal medicine treatment, FSH level reduction was observed in 7 of 12 women and menstruation resumption in 3, confirming positive potential.

Case Study Women's Health / Infertility

Hormone Level Improvement Effect of Herbal Medicine Treatment in Women with Premature Ovarian Insufficiency: A Case Study

Oh JK, Yun HS, Chung EJ, et al. BMC Complementary Medicine and Therapies (2023)
58% Hormone improvement rate
12 patients Participants

Summary

Kidney-tonifying essence-replenishing herbal medicine treatment was performed for 6 months in 12 women diagnosed with premature ovarian insufficiency before age 40. FSH, E2, and AMH level changes were tracked, and menstruation resumption was confirmed.

Key Conclusion

After herbal medicine treatment, FSH level reduction was observed in 7 of 12 women and menstruation resumption in 3, confirming positive potential.

Meta-Analysis Women's Health / Infertility

Comparison of Pregnancy Success Rates with Combined Korean Medicine and Assisted Reproductive Technology: A Systematic Review and Meta-Analysis

Kim DH, Park YS, Lee CH, et al.

Fertility and Sterility (2024)

1.38 Pregnancy rate odds ratio
3,280 patients Participants

Combined Korean medicine treatment was shown to significantly improve clinical pregnancy rates of assisted reproductive technology.

Meta-Analysis Women's Health / Infertility

Comparison of Pregnancy Success Rates with Combined Korean Medicine and Assisted Reproductive Technology: A Systematic Review and Meta-Analysis

Kim DH, Park YS, Lee CH, et al. Fertility and Sterility (2024)
1.38 Pregnancy rate odds ratio
3,280 patients Participants

Summary

Pregnancy success rates were compared between combined assisted reproductive technology and Korean medicine treatment versus assisted reproductive technology alone. A meta-analysis of 20 studies was performed to analyze clinical pregnancy rates, birth rates, and miscarriage rates.

Key Conclusion

Combined Korean medicine treatment was shown to significantly improve clinical pregnancy rates of assisted reproductive technology.

RCT Women's Health / Infertility

Dysmenorrhea Relief Effect of Combined TENS and Acupuncture

Han DJ, Choi MK, Yeon JW, et al.

Pain Medicine (2022)

81% Combination therapy improvement rate
70 patients Participants

Combined TENS and acupuncture showed significantly superior effects on dysmenorrhea relief compared to each monotherapy.

RCT Women's Health / Infertility

Dysmenorrhea Relief Effect of Combined TENS and Acupuncture

Han DJ, Choi MK, Yeon JW, et al. Pain Medicine (2022)
81% Combination therapy improvement rate
70 patients Participants

Summary

Seventy women with severe primary dysmenorrhea were compared among TENS alone, acupuncture alone, and TENS plus acupuncture combination groups. NRS pain scores and daily life interference were followed over 3 menstrual cycles.

Key Conclusion

Combined TENS and acupuncture showed significantly superior effects on dysmenorrhea relief compared to each monotherapy.

Cross-Sectional Women's Health / Infertility

Impact of Herbal Medicine Treatment on Cardiovascular Risk Factors in Menopausal Women: A Cross-Sectional Study

Lee YH, Koo BS, Kim JM, et al.

Journal of Ethnopharmacology (2023)

15% LDL reduction rate
280 patients Participants

Menopausal women receiving herbal medicine treatment had significantly lower LDL cholesterol and triglyceride levels.

Cross-Sectional Women's Health / Infertility

Impact of Herbal Medicine Treatment on Cardiovascular Risk Factors in Menopausal Women: A Cross-Sectional Study

Lee YH, Koo BS, Kim JM, et al. Journal of Ethnopharmacology (2023)
15% LDL reduction rate
280 patients Participants

Summary

Health check-up data of 280 postmenopausal women were analyzed to compare cardiovascular risk factors between herbal medicine treatment experience and non-experience groups. Blood pressure, blood lipids, fasting glucose, and abdominal obesity indicators were analyzed.

Key Conclusion

Menopausal women receiving herbal medicine treatment had significantly lower LDL cholesterol and triglyceride levels.

Narrative Review Women's Health / Infertility

Expert Consensus Study for Developing Korean Medicine Treatment Guidelines for PCOS

Song JY, Kim GH, Park EW, et al.

Journal of Korean Medicine (2025)

87% Expert consensus rate
40 experts Expert participation

Expert consensus guidelines for Korean medicine treatment of PCOS were derived and are expected to contribute to clinical standardization.

Narrative Review Women's Health / Infertility

Expert Consensus Study for Developing Korean Medicine Treatment Guidelines for PCOS

Song JY, Kim GH, Park EW, et al. Journal of Korean Medicine (2025)
87% Expert consensus rate
40 experts Expert participation

Summary

A Delphi survey was conducted with 40 Korean medicine experts to derive Korean medicine treatment guidelines for PCOS. Consensus was performed on pattern classification, prescription selection, treatment duration, and efficacy evaluation indicators.

Key Conclusion

Expert consensus guidelines for Korean medicine treatment of PCOS were derived and are expected to contribute to clinical standardization.