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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 55 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Systematic Review Wellness / Restoration

Systematic Review of Hepatoprotective Effects of Tonifying Herbal Medicine

Seo BK, Han CH, Choi JB, et al.

Journal of Ethnopharmacology (2024)

27% Liver enzyme improvement rate
980 patients Total participants

Tonifying herbal medicine is effective for hepatoprotection and can be utilized for liver disease prevention.

View Source 2024
Systematic Review Wellness / Restoration

Systematic Review of Hepatoprotective Effects of Tonifying Herbal Medicine

Seo BK, Han CH, Choi JB, et al. Journal of Ethnopharmacology (2024)
27% Liver enzyme improvement rate
980 patients Total participants

Summary

A systematic review evaluating hepatoprotective effects of tonifying herbal medicine. Analysis of 15 studies showed significant improvements in liver enzyme levels and hepatocyte protective effects in the tonifying herbal medicine administration group.

Key Conclusion

Tonifying herbal medicine is effective for hepatoprotection and can be utilized for liver disease prevention.

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Narrative Review Wellness / Restoration

Modern Interpretation and Health Promotion Application of Korean Medicine Yangsaeng Methods: A Narrative Review

Jung WS, Moon SK, Ko CN, et al.

BMC Complementary Medicine and Therapies (2021)

N/A Review study
50 studies Analyzed papers

Korean medicine yangsaeng methods can be the foundation for modern preventive medicine and integrative health management.

View Source 2021
Narrative Review Wellness / Restoration

Modern Interpretation and Health Promotion Application of Korean Medicine Yangsaeng Methods: A Narrative Review

Jung WS, Moon SK, Ko CN, et al. BMC Complementary Medicine and Therapies (2021)
N/A Review study
50 studies Analyzed papers

Summary

A narrative review reinterpreting traditional yangsaeng methods of Korean medicine classics from a modern health promotion perspective. Scientific evidence and modern application methods of traditional yangsaeng principles including diet, exercise, mental cultivation, and seasonal yangsaeng were organized.

Key Conclusion

Korean medicine yangsaeng methods can be the foundation for modern preventive medicine and integrative health management.

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Case Study Wellness / Restoration

Case Report of Korean Medicine Tonifying Treatment for Athletic Performance Enhancement

Chae YB, Park HJ, Lee HJ, et al.

Journal of Korean Medicine (2022)

39% Recovery speed improvement
6 patients Number of cases

Korean medicine tonifying treatment is useful for overtraining syndrome management and performance recovery in athletes.

View Source 2022
Case Study Wellness / Restoration

Case Report of Korean Medicine Tonifying Treatment for Athletic Performance Enhancement

Chae YB, Park HJ, Lee HJ, et al. Journal of Korean Medicine (2022)
39% Recovery speed improvement
6 patients Number of cases

Summary

A case report performing personalized tonifying herbal medicine and acupuncture for 8 weeks in 6 elite athletes complaining of overtraining syndrome. Improvements were observed in athletic performance, recovery speed, and fatigue indicators.

Key Conclusion

Korean medicine tonifying treatment is useful for overtraining syndrome management and performance recovery in athletes.

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Meta-Analysis Wellness / Restoration

Meta-Analysis of Mitochondrial Function Improvement by Herbal Tonifying Prescriptions

Hwang JH, Lee WB, Ahn CB, et al.

Evidence-Based Complementary and Alternative Medicine (2024)

18% ATP generating capacity increase
540 patients Total participants

Herbal tonifying prescriptions improve cellular energy metabolism through mitochondrial function improvement.

View Source 2024
Meta-Analysis Wellness / Restoration

Meta-Analysis of Mitochondrial Function Improvement by Herbal Tonifying Prescriptions

Hwang JH, Lee WB, Ahn CB, et al. Evidence-Based Complementary and Alternative Medicine (2024)
18% ATP generating capacity increase
540 patients Total participants

Summary

A meta-analysis evaluating the effect of herbal tonifying prescriptions on mitochondrial function. Analysis of 9 clinical studies showed significant improvements in ATP-generating capacity and mitochondrial membrane potential in the tonifying prescription group.

Key Conclusion

Herbal tonifying prescriptions improve cellular energy metabolism through mitochondrial function improvement.

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Cross-Sectional Wellness / Restoration

Association Between Korean Medicine Tonifying Treatment and Chronic Disease Prevention: A Cross-Sectional Analysis

Kim SY, Choi JB, Park KB, et al.

Journal of Ethnopharmacology (2023)

25% Chronic disease prevalence difference
1,200 patients Participants

Regular Korean medicine tonifying treatment shows significant association with chronic disease prevention.

View Source 2023
Cross-Sectional Wellness / Restoration

Association Between Korean Medicine Tonifying Treatment and Chronic Disease Prevention: A Cross-Sectional Analysis

Kim SY, Choi JB, Park KB, et al. Journal of Ethnopharmacology (2023)
25% Chronic disease prevalence difference
1,200 patients Participants

Summary

A cross-sectional analysis comparing chronic disease prevalence between 600 adults regularly receiving Korean medicine tonifying treatment and 600 non-users. The regular user group had significantly lower prevalence of hypertension, diabetes, and dyslipidemia.

Key Conclusion

Regular Korean medicine tonifying treatment shows significant association with chronic disease prevention.

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Before-After Wellness / Restoration

Pre-Post Comparison Study of Korean Medicine Tonifying Treatment for Office Worker Health Promotion

Ha IH, Lee JH, Kim MR, et al.

Journal of Korean Medicine (2023)

58% Fatigue reduction rate
50 patients Participants

Korean medicine tonifying treatment is effective for work fatigue recovery and health promotion in office workers.

View Source 2023
Before-After Wellness / Restoration

Pre-Post Comparison Study of Korean Medicine Tonifying Treatment for Office Worker Health Promotion

Ha IH, Lee JH, Kim MR, et al. Journal of Korean Medicine (2023)
58% Fatigue reduction rate
50 patients Participants

Summary

Customized tonifying herbal medicine and acupuncture were performed for 6 weeks in 50 office workers complaining of work fatigue, with pre-post comparison. Significant improvements appeared in fatigue, work concentration, and sleep quality.

Key Conclusion

Korean medicine tonifying treatment is effective for work fatigue recovery and health promotion in office workers.

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Cohort Study Wellness / Restoration

Korean Medicine Tonifying Program for Physical Strength Enhancement and Fall Prevention in Elderly: A Prospective Cohort Study

Cho KH, Jung IC, Park SJ, et al.

Evidence-Based Complementary and Alternative Medicine (2025)

41% Fall reduction rate
100 patients Participants

Korean medicine tonifying program is effective for physical strength enhancement and fall prevention in the elderly.

View Source 2025
Cohort Study Wellness / Restoration

Korean Medicine Tonifying Program for Physical Strength Enhancement and Fall Prevention in Elderly: A Prospective Cohort Study

Cho KH, Jung IC, Park SJ, et al. Evidence-Based Complementary and Alternative Medicine (2025)
41% Fall reduction rate
100 patients Participants

Summary

A prospective cohort study performing Korean medicine tonifying program (herbal medicine, qigong, moxibustion) for 6 months in 100 elderly aged 65 and older, tracking physical strength and fall frequency. Lower limb muscle strength and balance improved with reduced fall frequency.

Key Conclusion

Korean medicine tonifying program is effective for physical strength enhancement and fall prevention in the elderly.

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RCT Wellness / Restoration

Sleep Quality Improvement Effect of Korean Medicine Tonifying Treatment: A Randomized Controlled Trial

Moon SK, Ko CN, Jung WS, et al.

Pain Medicine (2023)

64% Sleep quality improvement rate
80 patients Participants

Tonifying herbal medicine treatment significantly improves sleep quality in chronic fatigue patients.

View Source 2023
RCT Wellness / Restoration

Sleep Quality Improvement Effect of Korean Medicine Tonifying Treatment: A Randomized Controlled Trial

Moon SK, Ko CN, Jung WS, et al. Pain Medicine (2023)
64% Sleep quality improvement rate
80 patients Participants

Summary

A randomized controlled trial comparing tonifying herbal medicine and placebo for 8 weeks in 80 chronic fatigue patients with comorbid sleep disturbance. Significant improvements appeared in PSQI scores, actigraphy sleep indicators, and daytime sleepiness scales.

Key Conclusion

Tonifying herbal medicine treatment significantly improves sleep quality in chronic fatigue patients.

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Systematic Review Wellness / Restoration

Systematic Review of Immunoglobulin Changes After Tonifying Medicine Administration

Kim AR, Kwon CY, Lee SH, et al.

BMC Complementary Medicine and Therapies (2024)

21% IgA increase rate
850 patients Total participants

Tonifying medicine significantly improves immunoglobulin levels and contributes to strengthening humoral immunity.

View Source 2024
Systematic Review Wellness / Restoration

Systematic Review of Immunoglobulin Changes After Tonifying Medicine Administration

Kim AR, Kwon CY, Lee SH, et al. BMC Complementary Medicine and Therapies (2024)
21% IgA increase rate
850 patients Total participants

Summary

A systematic review evaluating immunoglobulin (IgA, IgG, IgM) changes after tonifying medicine administration. Analysis of 13 studies showed significantly increased IgA and IgG levels in the tonifying medicine administration group.

Key Conclusion

Tonifying medicine significantly improves immunoglobulin levels and contributes to strengthening humoral immunity.

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Narrative Review Wellness / Restoration

Theoretical Foundation and Clinical Application of Korean Medicine Holistic Health Model: A Narrative Review

Ko SG, Shin BC, Lee MS, et al.

Journal of Ethnopharmacology (2021)

N/A Review study
42 studies Analyzed papers

The Korean medicine holistic health model can contribute to development of modern preventive medicine and integrative medicine.

View Source 2021
Narrative Review Wellness / Restoration

Theoretical Foundation and Clinical Application of Korean Medicine Holistic Health Model: A Narrative Review

Ko SG, Shin BC, Lee MS, et al. Journal of Ethnopharmacology (2021)
N/A Review study
42 studies Analyzed papers

Summary

Theoretical foundation of the Korean medicine holistic health model was narratively reviewed, and an integrative health management framework encompassing yangsaeng, tonification, and mental health was presented. Applicability from a modern preventive medicine perspective was discussed.

Key Conclusion

The Korean medicine holistic health model can contribute to development of modern preventive medicine and integrative medicine.

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Cross-Sectional Wellness / Restoration

Analysis of Health-Related Quality of Life in Korean Medicine Tonifying Program Participants: A Cross-Sectional Study

Choi IH, Lee BH, Kim JI, et al.

Evidence-Based Complementary and Alternative Medicine (2022)

89% Good quality of life ratio
700 patients Participants

Korean medicine tonifying program participation is closely associated with improved health-related quality of life.

View Source 2022
Cross-Sectional Wellness / Restoration

Analysis of Health-Related Quality of Life in Korean Medicine Tonifying Program Participants: A Cross-Sectional Study

Choi IH, Lee BH, Kim JI, et al. Evidence-Based Complementary and Alternative Medicine (2022)
89% Good quality of life ratio
700 patients Participants

Summary

A cross-sectional study comparing health-related quality of life between 350 adults participating in Korean medicine tonifying programs and 350 non-participants. The program participation group showed significantly higher scores in all subdomains of EQ-5D and SF-36.

Key Conclusion

Korean medicine tonifying program participation is closely associated with improved health-related quality of life.

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RCT Wellness / Restoration

Changes in Gut Microbiota Diversity with Korean Medicine Tonifying Treatment: A Randomized Controlled Trial

Yun MH, Lee JW, Kim HJ, et al.

BMC Complementary Medicine and Therapies (2025)

24% Microbial diversity increase
60 patients Participants

Tonifying herbal medicine contributes to overall health promotion by increasing gut microbiota diversity.

View Source 2025
RCT Wellness / Restoration

Changes in Gut Microbiota Diversity with Korean Medicine Tonifying Treatment: A Randomized Controlled Trial

Yun MH, Lee JW, Kim HJ, et al. BMC Complementary Medicine and Therapies (2025)
24% Microbial diversity increase
60 patients Participants

Summary

A randomized controlled trial comparing tonifying herbal medicine and placebo for 8 weeks in 60 healthy adults. Gut microbiota analysis showed significant increases in beneficial bacteria ratio and microbial diversity in the tonifying herbal medicine group.

Key Conclusion

Tonifying herbal medicine contributes to overall health promotion by increasing gut microbiota diversity.

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