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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 83 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
RCT Skin Conditions

Immune Modulation Effect of Acupuncture in Psoriasis Patients: An RCT

Kim DS, Lee BJ, Nakamura K, et al.

Acupuncture in Medicine (2025)

80 patients Participants
38% PASI improvement
12 weeks Treatment duration

Acupuncture is effective for immune indicator modulation and symptom improvement in psoriasis patients.

View Source 2025
RCT Skin Conditions

Immune Modulation Effect of Acupuncture in Psoriasis Patients: An RCT

Kim DS, Lee BJ, Nakamura K, et al. Acupuncture in Medicine (2025)
80 patients Participants
38% PASI improvement
12 weeks Treatment duration

Summary

Eighty patients with moderate psoriasis were randomly assigned to acupuncture or sham acupuncture groups and compared over 12 weeks. The acupuncture group showed PASI score reduction along with significant decreases in blood IL-17 and TNF-α.

Key Conclusion

Acupuncture is effective for immune indicator modulation and symptom improvement in psoriasis patients.

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Before-After Skin Conditions

Skin Barrier Recovery Effect of Jaungo in Atopic Dermatitis Patients: A Pre-Post Comparison

Jung EK, Moon HJ, et al.

Skin Pharmacology and Physiology (2024)

50 patients Participants
42% TEWL reduction
6 weeks Treatment duration

Jaungo is an effective Korean medicine topical preparation for restoring the skin barrier in atopic dermatitis patients.

View Source 2024
Before-After Skin Conditions

Skin Barrier Recovery Effect of Jaungo in Atopic Dermatitis Patients: A Pre-Post Comparison

Jung EK, Moon HJ, et al. Skin Pharmacology and Physiology (2024)
50 patients Participants
42% TEWL reduction
6 weeks Treatment duration

Summary

Jaungo was applied for 6 weeks to 50 patients with atopic dermatitis, and TEWL, skin hydration, SCORAD, and ceramide levels were measured. All four indicators significantly improved.

Key Conclusion

Jaungo is an effective Korean medicine topical preparation for restoring the skin barrier in atopic dermatitis patients.

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Systematic Review Skin Conditions

Effect of Korean Medicine Combination Therapy for Acne Patients: A Systematic Review

Park HJ, Choi KE, et al.

Journal of Alternative and Complementary Medicine (2022)

25 studies Included studies
20 studies Positive results
Moderate Evidence level

Korean medicine is an effective complementary treatment for acne management, with particularly promising results from combined acupuncture and herbal medicine.

View Source 2022
Systematic Review Skin Conditions

Effect of Korean Medicine Combination Therapy for Acne Patients: A Systematic Review

Park HJ, Choi KE, et al. Journal of Alternative and Complementary Medicine (2022)
25 studies Included studies
20 studies Positive results
Moderate Evidence level

Summary

Twenty-five studies on Korean medicine treatment (herbal medicine, acupuncture, pharmacopuncture, topical preparations) for acne were systematically reviewed. Most studies reported lesion count reduction and GAGS score improvement.

Key Conclusion

Korean medicine is an effective complementary treatment for acne management, with particularly promising results from combined acupuncture and herbal medicine.

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RCT Skin Conditions

Histamine Release Inhibition Effect of Herbal Medicine for Chronic Urticaria: Basic and Clinical Studies

Yang WS, Kim HN, Liu J, et al.

Phytomedicine (2023)

60 patients Participants
65% UAS7 improvement rate
p<0.01 Histamine reduction

Modified Sopung-san effectively manages chronic urticaria through histamine release inhibition.

View Source 2023
RCT Skin Conditions

Histamine Release Inhibition Effect of Herbal Medicine for Chronic Urticaria: Basic and Clinical Studies

Yang WS, Kim HN, Liu J, et al. Phytomedicine (2023)
60 patients Participants
65% UAS7 improvement rate
p<0.01 Histamine reduction

Summary

Histamine release inhibition effects of modified Sopung-san were evaluated in 60 patients with chronic spontaneous urticaria through in vitro experiments and clinical trials. The herbal medicine group showed significantly reduced UAS7 scores and blood histamine.

Key Conclusion

Modified Sopung-san effectively manages chronic urticaria through histamine release inhibition.

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Cohort Study Skin Conditions

Effect of Combined Herbal Medicine-Topical Preparation Treatment for Chronic Eczema: A Prospective Cohort Study

Lee MK, Seo YJ, et al.

Contact Dermatitis (2024)

100 patients Participants
72% Symptom improvement rate
16 weeks Follow-up period

Combined herbal medicine-topical preparation treatment shows sustained effects superior to steroid monotherapy in chronic eczema management.

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Cohort Study Skin Conditions

Effect of Combined Herbal Medicine-Topical Preparation Treatment for Chronic Eczema: A Prospective Cohort Study

Lee MK, Seo YJ, et al. Contact Dermatitis (2024)
100 patients Participants
72% Symptom improvement rate
16 weeks Follow-up period

Summary

One hundred patients with chronic eczema were followed for 16 weeks, divided into a combined herbal medicine-topical preparation group and a steroid topical preparation alone group. The combination treatment group showed greater symptom improvement and lower recurrence rates.

Key Conclusion

Combined herbal medicine-topical preparation treatment shows sustained effects superior to steroid monotherapy in chronic eczema management.

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Meta-Analysis Skin Conditions

Effect of Korean Medicine Treatment for Plaque Psoriasis: A Systematic Review and Meta-Analysis

Cho SH, Park JE, Tanaka M, et al.

Journal of Dermatological Treatment (2023)

20 studies Included studies
1,640 patients Total participants
WMD -5.8 PASI reduction

Korean medicine treatment shows significant efficacy in improving PASI scores for plaque psoriasis.

View Source 2023
Meta-Analysis Skin Conditions

Effect of Korean Medicine Treatment for Plaque Psoriasis: A Systematic Review and Meta-Analysis

Cho SH, Park JE, Tanaka M, et al. Journal of Dermatological Treatment (2023)
20 studies Included studies
1,640 patients Total participants
WMD -5.8 PASI reduction

Summary

Twenty studies (total 1,640 patients) on Korean medicine treatment (herbal medicine, acupuncture, topical preparations) for plaque psoriasis were meta-analyzed. The Korean medicine treatment group showed significantly reduced PASI scores compared to controls.

Key Conclusion

Korean medicine treatment shows significant efficacy in improving PASI scores for plaque psoriasis.

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RCT Skin Conditions

EASI Improvement Effect of Oral Herbal Medicine for Moderate Atopic Dermatitis: A Double-Blind RCT

Kim JH, Lee SY, Park WC, et al.

Dermatologic Therapy (2024)

150 patients Participants
58% EASI-75 achievement rate
12 weeks Treatment duration

Oral herbal medicine is effective for EASI score improvement in moderate atopic dermatitis with few side effects.

View Source 2024
RCT Skin Conditions

EASI Improvement Effect of Oral Herbal Medicine for Moderate Atopic Dermatitis: A Double-Blind RCT

Kim JH, Lee SY, Park WC, et al. Dermatologic Therapy (2024)
150 patients Participants
58% EASI-75 achievement rate
12 weeks Treatment duration

Summary

One hundred fifty patients with moderate atopic dermatitis were randomly assigned in a double-blind manner to oral herbal medicine or placebo groups and compared over 12 weeks. The herbal medicine group showed significantly decreased EASI scores and improved quality of life.

Key Conclusion

Oral herbal medicine is effective for EASI score improvement in moderate atopic dermatitis with few side effects.

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RCT Skin Conditions

Effect of Personalized Herbal Treatment for Atopic Dermatitis: A Double-Blind Randomized Controlled Trial

Yoo SR, Oh HG, Kim NR, et al.

Journal of Dermatological Treatment (2023)

108 subjects Participants
SCORAD 47.8% reduction Skin Symptom Improvement
IgE normalization Immune Modulation

Personalized herbal medicine based on pattern differentiation is an effective treatment method for symptom relief and immune modulation in atopic dermatitis.

View Source 2023
RCT Skin Conditions

Effect of Personalized Herbal Treatment for Atopic Dermatitis: A Double-Blind Randomized Controlled Trial

Yoo SR, Oh HG, Kim NR, et al. Journal of Dermatological Treatment (2023)
108 subjects Participants
SCORAD 47.8% reduction Skin Symptom Improvement
IgE normalization Immune Modulation

Summary

One hundred eight patients with moderate atopic dermatitis were divided into a personalized herbal medicine group and a placebo group and treated for 12 weeks. SCORAD scores significantly decreased in the herbal group, and serum IgE levels stabilized.

Key Conclusion

Personalized herbal medicine based on pattern differentiation is an effective treatment method for symptom relief and immune modulation in atopic dermatitis.

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Cohort Study Skin Conditions

Effect of Korean Medicine Combination Therapy in Psoriasis Patients: A Prospective Cohort Study

Yun YH, Choi JE, Kim KJ, et al.

Journal of Alternative and Complementary Medicine (2023)

41% PASI 75 achievement rate
62% Quality of life improvement
98 patients Study population

Korean medicine combination therapy contributes to reducing skin lesions and improving quality of life in psoriasis, with expected synergistic effects when combined with conventional treatment.

View Source 2023
Cohort Study Skin Conditions

Effect of Korean Medicine Combination Therapy in Psoriasis Patients: A Prospective Cohort Study

Yun YH, Choi JE, Kim KJ, et al. Journal of Alternative and Complementary Medicine (2023)
41% PASI 75 achievement rate
62% Quality of life improvement
98 patients Study population

Summary

A cohort study observing PASI score changes after 16 weeks of Korean medicine combination therapy combining herbal medicine and acupuncture in 98 patients with mild-to-moderate psoriasis. PASI 75 achievement rate was 41%, and patient-reported outcomes (DLQI) showed an average 62% improvement in quality of life.

Key Conclusion

Korean medicine combination therapy contributes to reducing skin lesions and improving quality of life in psoriasis, with expected synergistic effects when combined with conventional treatment.

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Systematic Review Skin Conditions

Systematic Review of Acupuncture Treatment for Chronic Urticaria

Lee HJ, Park YC, Kim KS, et al.

European Journal of Integrative Medicine (2022)

37% Additional symptom reduction
29% Recurrence reduction
11 studies Analyzed studies

Acupuncture as adjunctive treatment for chronic urticaria shows significant effects on symptom control and recurrence prevention.

View Source 2022
Systematic Review Skin Conditions

Systematic Review of Acupuncture Treatment for Chronic Urticaria

Lee HJ, Park YC, Kim KS, et al. European Journal of Integrative Medicine (2022)
37% Additional symptom reduction
29% Recurrence reduction
11 studies Analyzed studies

Summary

Eleven RCTs evaluating acupuncture treatment for chronic spontaneous urticaria were systematically analyzed. The acupuncture combination group showed an additional 37% reduction in UAS7 (urticaria activity score) compared to antihistamines alone, with 29% lower recurrence rates at 6-month follow-up.

Key Conclusion

Acupuncture as adjunctive treatment for chronic urticaria shows significant effects on symptom control and recurrence prevention.

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RCT Skin Conditions

Effect of Herbal Medicine Treatment for Atopic Dermatitis: A Randomized Controlled Trial

Choi IH, Kim S, Kim Y, et al.

Annals of Dermatology (2023)

48% SCORAD index reduction
55% Pruritus improvement
12 weeks Treatment duration

Herbal medicine treatment significantly improves skin lesions and pruritus in atopic dermatitis and may contribute to reducing steroid use.

View Source 2023
RCT Skin Conditions

Effect of Herbal Medicine Treatment for Atopic Dermatitis: A Randomized Controlled Trial

Choi IH, Kim S, Kim Y, et al. Annals of Dermatology (2023)
48% SCORAD index reduction
55% Pruritus improvement
12 weeks Treatment duration

Summary

Seventy-two patients with moderate atopic dermatitis were compared between herbal medicine and placebo groups for 12 weeks. The herbal medicine group showed an average 48% reduction in SCORAD index and 55% improvement in pruritus VAS. Serum IgE levels also significantly decreased, confirming immunomodulatory effects.

Key Conclusion

Herbal medicine treatment significantly improves skin lesions and pruritus in atopic dermatitis and may contribute to reducing steroid use.

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