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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 83 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Before-After Skin Conditions

Effect of Herbal Bath Therapy on Autonomic Nervous System and Skin Health in Chronic Stress Patients: A Pre-Post Comparison Study

Roh JD, Kang YH, Lee EJ, et al.

Complementary Therapies in Clinical Practice (2024)

31% Parasympathetic activity increase
45 patients Participants
8 weeks Application period

Herbal bath therapy is an effective wellness treatment for autonomic balance recovery and skin health improvement.

View Source 2024
Before-After Skin Conditions

Effect of Herbal Bath Therapy on Autonomic Nervous System and Skin Health in Chronic Stress Patients: A Pre-Post Comparison Study

Roh JD, Kang YH, Lee EJ, et al. Complementary Therapies in Clinical Practice (2024)
31% Parasympathetic activity increase
45 patients Participants
8 weeks Application period

Summary

Herbal bath (based on Artemisia, Angelica, Cnidium) was applied twice weekly for 8 weeks to 45 adults complaining of chronic stress. HRV analysis showed 31% increase in parasympathetic activity, with significantly improved skin hydration and elasticity.

Key Conclusion

Herbal bath therapy is an effective wellness treatment for autonomic balance recovery and skin health improvement.

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RCT Skin Conditions

EASI Improvement Effect of Oral Herbal Medicine for Moderate Atopic Dermatitis: A Double-Blind RCT

Kim JH, Lee SY, Park WC, et al.

Dermatologic Therapy (2024)

150 patients Participants
58% EASI-75 achievement rate
12 weeks Treatment duration

Oral herbal medicine is effective for EASI score improvement in moderate atopic dermatitis with few side effects.

View Source 2024
RCT Skin Conditions

EASI Improvement Effect of Oral Herbal Medicine for Moderate Atopic Dermatitis: A Double-Blind RCT

Kim JH, Lee SY, Park WC, et al. Dermatologic Therapy (2024)
150 patients Participants
58% EASI-75 achievement rate
12 weeks Treatment duration

Summary

One hundred fifty patients with moderate atopic dermatitis were randomly assigned in a double-blind manner to oral herbal medicine or placebo groups and compared over 12 weeks. The herbal medicine group showed significantly decreased EASI scores and improved quality of life.

Key Conclusion

Oral herbal medicine is effective for EASI score improvement in moderate atopic dermatitis with few side effects.

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Meta-Analysis Skin Conditions

Effect of Korean Medicine Treatment for Plaque Psoriasis: A Systematic Review and Meta-Analysis

Cho SH, Park JE, Tanaka M, et al.

Journal of Dermatological Treatment (2023)

20 studies Included studies
1,640 patients Total participants
WMD -5.8 PASI reduction

Korean medicine treatment shows significant efficacy in improving PASI scores for plaque psoriasis.

View Source 2023
Meta-Analysis Skin Conditions

Effect of Korean Medicine Treatment for Plaque Psoriasis: A Systematic Review and Meta-Analysis

Cho SH, Park JE, Tanaka M, et al. Journal of Dermatological Treatment (2023)
20 studies Included studies
1,640 patients Total participants
WMD -5.8 PASI reduction

Summary

Twenty studies (total 1,640 patients) on Korean medicine treatment (herbal medicine, acupuncture, topical preparations) for plaque psoriasis were meta-analyzed. The Korean medicine treatment group showed significantly reduced PASI scores compared to controls.

Key Conclusion

Korean medicine treatment shows significant efficacy in improving PASI scores for plaque psoriasis.

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Cohort Study Skin Conditions

Effect of Combined Herbal Medicine-Topical Preparation Treatment for Chronic Eczema: A Prospective Cohort Study

Lee MK, Seo YJ, et al.

Contact Dermatitis (2024)

100 patients Participants
72% Symptom improvement rate
16 weeks Follow-up period

Combined herbal medicine-topical preparation treatment shows sustained effects superior to steroid monotherapy in chronic eczema management.

View Source 2024
Cohort Study Skin Conditions

Effect of Combined Herbal Medicine-Topical Preparation Treatment for Chronic Eczema: A Prospective Cohort Study

Lee MK, Seo YJ, et al. Contact Dermatitis (2024)
100 patients Participants
72% Symptom improvement rate
16 weeks Follow-up period

Summary

One hundred patients with chronic eczema were followed for 16 weeks, divided into a combined herbal medicine-topical preparation group and a steroid topical preparation alone group. The combination treatment group showed greater symptom improvement and lower recurrence rates.

Key Conclusion

Combined herbal medicine-topical preparation treatment shows sustained effects superior to steroid monotherapy in chronic eczema management.

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RCT Skin Conditions

Histamine Release Inhibition Effect of Herbal Medicine for Chronic Urticaria: Basic and Clinical Studies

Yang WS, Kim HN, Liu J, et al.

Phytomedicine (2023)

60 patients Participants
65% UAS7 improvement rate
p<0.01 Histamine reduction

Modified Sopung-san effectively manages chronic urticaria through histamine release inhibition.

View Source 2023
RCT Skin Conditions

Histamine Release Inhibition Effect of Herbal Medicine for Chronic Urticaria: Basic and Clinical Studies

Yang WS, Kim HN, Liu J, et al. Phytomedicine (2023)
60 patients Participants
65% UAS7 improvement rate
p<0.01 Histamine reduction

Summary

Histamine release inhibition effects of modified Sopung-san were evaluated in 60 patients with chronic spontaneous urticaria through in vitro experiments and clinical trials. The herbal medicine group showed significantly reduced UAS7 scores and blood histamine.

Key Conclusion

Modified Sopung-san effectively manages chronic urticaria through histamine release inhibition.

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Systematic Review Skin Conditions

Effect of Korean Medicine Combination Therapy for Acne Patients: A Systematic Review

Park HJ, Choi KE, et al.

Journal of Alternative and Complementary Medicine (2022)

25 studies Included studies
20 studies Positive results
Moderate Evidence level

Korean medicine is an effective complementary treatment for acne management, with particularly promising results from combined acupuncture and herbal medicine.

View Source 2022
Systematic Review Skin Conditions

Effect of Korean Medicine Combination Therapy for Acne Patients: A Systematic Review

Park HJ, Choi KE, et al. Journal of Alternative and Complementary Medicine (2022)
25 studies Included studies
20 studies Positive results
Moderate Evidence level

Summary

Twenty-five studies on Korean medicine treatment (herbal medicine, acupuncture, pharmacopuncture, topical preparations) for acne were systematically reviewed. Most studies reported lesion count reduction and GAGS score improvement.

Key Conclusion

Korean medicine is an effective complementary treatment for acne management, with particularly promising results from combined acupuncture and herbal medicine.

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Before-After Skin Conditions

Skin Barrier Recovery Effect of Jaungo in Atopic Dermatitis Patients: A Pre-Post Comparison

Jung EK, Moon HJ, et al.

Skin Pharmacology and Physiology (2024)

50 patients Participants
42% TEWL reduction
6 weeks Treatment duration

Jaungo is an effective Korean medicine topical preparation for restoring the skin barrier in atopic dermatitis patients.

View Source 2024
Before-After Skin Conditions

Skin Barrier Recovery Effect of Jaungo in Atopic Dermatitis Patients: A Pre-Post Comparison

Jung EK, Moon HJ, et al. Skin Pharmacology and Physiology (2024)
50 patients Participants
42% TEWL reduction
6 weeks Treatment duration

Summary

Jaungo was applied for 6 weeks to 50 patients with atopic dermatitis, and TEWL, skin hydration, SCORAD, and ceramide levels were measured. All four indicators significantly improved.

Key Conclusion

Jaungo is an effective Korean medicine topical preparation for restoring the skin barrier in atopic dermatitis patients.

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RCT Skin Conditions

Immune Modulation Effect of Acupuncture in Psoriasis Patients: An RCT

Kim DS, Lee BJ, Nakamura K, et al.

Acupuncture in Medicine (2025)

80 patients Participants
38% PASI improvement
12 weeks Treatment duration

Acupuncture is effective for immune indicator modulation and symptom improvement in psoriasis patients.

View Source 2025
RCT Skin Conditions

Immune Modulation Effect of Acupuncture in Psoriasis Patients: An RCT

Kim DS, Lee BJ, Nakamura K, et al. Acupuncture in Medicine (2025)
80 patients Participants
38% PASI improvement
12 weeks Treatment duration

Summary

Eighty patients with moderate psoriasis were randomly assigned to acupuncture or sham acupuncture groups and compared over 12 weeks. The acupuncture group showed PASI score reduction along with significant decreases in blood IL-17 and TNF-α.

Key Conclusion

Acupuncture is effective for immune indicator modulation and symptom improvement in psoriasis patients.

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Narrative Review Skin Conditions

Role of Pharmacopuncture in Korean Medicine Skin Treatment: A Literature Review

Baek SH, Yoon KJ, et al.

Journal of Pharmacopuncture (2022)

28 studies Reviewed papers
4 types Disease groups
Hwangryeonhaedok-tang Most frequent prescription

Pharmacopuncture is promising as adjunctive treatment for various skin diseases, but standardized protocol development is needed.

View Source 2022
Narrative Review Skin Conditions

Role of Pharmacopuncture in Korean Medicine Skin Treatment: A Literature Review

Baek SH, Yoon KJ, et al. Journal of Pharmacopuncture (2022)
28 studies Reviewed papers
4 types Disease groups
Hwangryeonhaedok-tang Most frequent prescription

Summary

Twenty-eight studies on pharmacopuncture treatment for skin diseases (atopic dermatitis, psoriasis, acne, urticaria, etc.) were comprehensively reviewed. Hwangryeonhaedok-tang pharmacopuncture and anti-inflammatory pharmacopuncture were most frequently studied.

Key Conclusion

Pharmacopuncture is promising as adjunctive treatment for various skin diseases, but standardized protocol development is needed.

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Meta-Analysis Skin Conditions

Effect of Acupuncture for Chronic Urticaria: A Meta-Analysis

Son HJ, Kim YW, Chen X, et al.

Allergy (2023)

10 studies Included studies
820 patients Total participants
SMD -0.82 Effect size

Acupuncture shows significant efficacy for symptom management and reducing drug use in chronic urticaria.

View Source 2023
Meta-Analysis Skin Conditions

Effect of Acupuncture for Chronic Urticaria: A Meta-Analysis

Son HJ, Kim YW, Chen X, et al. Allergy (2023)
10 studies Included studies
820 patients Total participants
SMD -0.82 Effect size

Summary

Ten RCTs (total 820 patients) evaluating acupuncture for chronic spontaneous urticaria were meta-analyzed. The acupuncture group showed significant reductions in UAS7 scores and antihistamine use.

Key Conclusion

Acupuncture shows significant efficacy for symptom management and reducing drug use in chronic urticaria.

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RCT Skin Conditions

Effect of Combined Herbal Medicine-LED Light Therapy Intervention for Acne Patients: An RCT

Lim SY, Park GH, et al.

Dermatologic Therapy (2024)

90 patients Participants
3-arm comparison Study design
74% Lesion reduction rate

Combined herbal medicine and LED light therapy shows synergistic effects in acne treatment.

View Source 2024
RCT Skin Conditions

Effect of Combined Herbal Medicine-LED Light Therapy Intervention for Acne Patients: An RCT

Lim SY, Park GH, et al. Dermatologic Therapy (2024)
90 patients Participants
3-arm comparison Study design
74% Lesion reduction rate

Summary

Ninety patients with moderate acne were randomly assigned to herbal medicine plus LED, herbal medicine alone, or LED alone groups and compared over 8 weeks. The combination group showed the greatest reductions in inflammatory lesion counts and GAGS scores.

Key Conclusion

Combined herbal medicine and LED light therapy shows synergistic effects in acne treatment.

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Cross-Sectional Skin Conditions

Correlation Between Korean Medicine Pattern Differentiation and Skin Microbiota in Eczema Patients: A Cross-Sectional Study

Cho KM, Lee SH, et al.

Journal of Investigative Dermatology (2023)

120 patients Analysis population
4 types Pattern types
p<0.01 Microbiota differences

Korean medicine pattern differentiation in eczema is associated with skin microbiota composition and can be utilized for pattern-tailored treatment.

View Source 2023
Cross-Sectional Skin Conditions

Correlation Between Korean Medicine Pattern Differentiation and Skin Microbiota in Eczema Patients: A Cross-Sectional Study

Cho KM, Lee SH, et al. Journal of Investigative Dermatology (2023)
120 patients Analysis population
4 types Pattern types
p<0.01 Microbiota differences

Summary

A cross-sectional study performing Korean medicine pattern differentiation and skin microbiota analysis in 120 patients with eczema. The damp-heat pattern showed significantly higher Staphylococcus aureus ratios.

Key Conclusion

Korean medicine pattern differentiation in eczema is associated with skin microbiota composition and can be utilized for pattern-tailored treatment.

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