금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
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Total 83 papers

Cross-Sectional Skin Conditions

Cross-Sectional Analysis of Acupuncture Effects for Acute Herpes Zoster Pain

문재환, 박소영, 김대원, et al.

Journal of Pain Research (2023)

200 patients Analysis subjects
-2.8 points Additional VAS reduction
31.4% Analgesic reduction rate

Combined acupuncture in acute herpes zoster results in faster pain control and reduced analgesic use, making it clinically significant.

Cross-Sectional Skin Conditions

Cross-Sectional Analysis of Acupuncture Effects for Acute Herpes Zoster Pain

문재환, 박소영, 김대원, et al. Journal of Pain Research (2023)
200 patients Analysis subjects
-2.8 points Additional VAS reduction
31.4% Analgesic reduction rate

Summary

Medical records of 200 patients with acute herpes zoster were retrospectively analyzed to compare pain control effects between acupuncture combination and antiviral alone groups. The acupuncture combination group showed significantly faster VAS score reduction and less analgesic use. Progression rate to post-herpetic neuralgia also showed lower trend in the combination group.

Key Conclusion

Combined acupuncture in acute herpes zoster results in faster pain control and reduced analgesic use, making it clinically significant.

Before-After Skin Conditions

Pre-Post Comparison Study of Korean Medicine Combination Therapy for Female Pattern Baldness

윤서희, 김정훈, 이수민, et al.

한방안이비인후피부과학회지 (2024)

52 patients Target patients
+28.6% Hair density increase
83.5% Scalp health improvement rate

Korean medicine combination therapy is effective for hair growth promotion and scalp environment improvement in female pattern baldness, and is particularly useful for hormonal alopecia.

Before-After Skin Conditions

Pre-Post Comparison Study of Korean Medicine Combination Therapy for Female Pattern Baldness

윤서희, 김정훈, 이수민, et al. 한방안이비인후피부과학회지 (2024)
52 patients Target patients
+28.6% Hair density increase
83.5% Scalp health improvement rate

Summary

Combination therapy including herbal medicine (modified Yukmijihwang-tang), acupuncture, and scalp pharmacopuncture was performed for 16 weeks on 52 patients with female pattern baldness. Hair density, hair diameter, and scalp health scores all significantly improved in pre-post comparison. Improvement was particularly pronounced in postmenopausal women.

Key Conclusion

Korean medicine combination therapy is effective for hair growth promotion and scalp environment improvement in female pattern baldness, and is particularly useful for hormonal alopecia.

Meta-Analysis Skin Conditions

Systematic Review and Meta-Analysis of Acupuncture Treatment for Alopecia Areata

신재욱, 김하늘, 이보람, et al.

Acupuncture in Medicine (2024)

15 studies Included studies
RR 1.58 Regrowth risk ratio
p=0.003 Statistical significance

Acupuncture is an effective complementary therapy for promoting hair regrowth and preventing recurrence in alopecia areata, with synergistic effects expected when combined with conventional treatment.

Meta-Analysis Skin Conditions

Systematic Review and Meta-Analysis of Acupuncture Treatment for Alopecia Areata

신재욱, 김하늘, 이보람, et al. Acupuncture in Medicine (2024)
15 studies Included studies
RR 1.58 Regrowth risk ratio
p=0.003 Statistical significance

Summary

Acupuncture treatment efficacy in alopecia areata patients was systematically reviewed. A meta-analysis of 15 RCTs showed significant improvement in hair regrowth rate and recurrence prevention in the acupuncture group compared to corticosteroid monotherapy. Acupuncture was found to contribute to follicle reactivation through increased scalp blood flow.

Key Conclusion

Acupuncture is an effective complementary therapy for promoting hair regrowth and preventing recurrence in alopecia areata, with synergistic effects expected when combined with conventional treatment.

RCT Skin Conditions

Randomized Controlled Trial of Herbal Medicine Topical Preparation for Contact Dermatitis

Kwon OJ, Seo YJ, Han DH, et al.

Contact Dermatitis (2023)

Equivalent effect Steroid comparison
70 patients Participants
Rebound reduced Safety

Herbal medicine topical preparation shows effects equivalent to steroids for contact dermatitis with lower rebound risk.

RCT Skin Conditions

Randomized Controlled Trial of Herbal Medicine Topical Preparation for Contact Dermatitis

Kwon OJ, Seo YJ, Han DH, et al. Contact Dermatitis (2023)
Equivalent effect Steroid comparison
70 patients Participants
Rebound reduced Safety

Summary

Seventy patients with contact dermatitis were compared between herbal medicine topical preparation (Coptis-Phellodendron ointment) and steroid ointment groups over 4 weeks. The herbal medicine group showed erythema and pruritus improvement equivalent to steroids with less rebound phenomenon.

Key Conclusion

Herbal medicine topical preparation shows effects equivalent to steroids for contact dermatitis with lower rebound risk.

Narrative Review Skin Conditions

Narrative Review of Combined Herbal Medicine and Scalp Acupuncture for Male Pattern Baldness

Ryu BH, Kim KH, Song MY, et al.

Journal of Cosmetic Dermatology (2024)

20 studies Reviewed papers
Hair density increased Main effect
Minoxidil alternative Clinical significance

Combined herbal medicine and scalp acupuncture has potential as a non-pharmacological alternative for male pattern baldness.

Narrative Review Skin Conditions

Narrative Review of Combined Herbal Medicine and Scalp Acupuncture for Male Pattern Baldness

Ryu BH, Kim KH, Song MY, et al. Journal of Cosmetic Dermatology (2024)
20 studies Reviewed papers
Hair density increased Main effect
Minoxidil alternative Clinical significance

Summary

Twenty papers on combined effects of herbal medicine (He Shou Wu, deer antler) and scalp acupuncture for male pattern baldness were reviewed. Korean medicine treatment showed effects on hair density improvement equivalent or complementary to minoxidil.

Key Conclusion

Combined herbal medicine and scalp acupuncture has potential as a non-pharmacological alternative for male pattern baldness.

Case Study Skin Conditions

Case Report of Herbal Medicine (Danggwisayeok-tang) for Cold Urticaria

Yoon SH, Cho WS, Lee AR, et al.

Case Reports in Dermatology (2023)

5 patients Cases
8°C Threshold change
8 weeks Administration period

Danggwisayeok-tang is effective for body temperature regulation and peripheral circulation improvement in cold urticaria.

Case Study Skin Conditions

Case Report of Herbal Medicine (Danggwisayeok-tang) for Cold Urticaria

Yoon SH, Cho WS, Lee AR, et al. Case Reports in Dermatology (2023)
5 patients Cases
8°C Threshold change
8 weeks Administration period

Summary

Danggwisayeok-tang was administered for 8 weeks to 5 patients with cold urticaria. The threshold for urticaria occurrence in cold stimulation provocation test decreased by an average of 8°C, and symptoms significantly improved.

Key Conclusion

Danggwisayeok-tang is effective for body temperature regulation and peripheral circulation improvement in cold urticaria.

Cross-Sectional Skin Conditions

Effect of Herbal Medicine Facial Cleanser for Seborrheic Dermatitis: A Cross-Sectional Analysis

Baek IH, Kim SY, Park CW, et al.

Dermatologic Therapy (2024)

200 patients Participants
35% Erythema reduction
42% Dandruff reduction

Herbal medicine facial cleanser is an effective adjunctive method for managing scalp symptoms of seborrheic dermatitis.

Cross-Sectional Skin Conditions

Effect of Herbal Medicine Facial Cleanser for Seborrheic Dermatitis: A Cross-Sectional Analysis

Baek IH, Kim SY, Park CW, et al. Dermatologic Therapy (2024)
200 patients Participants
35% Erythema reduction
42% Dandruff reduction

Summary

Symptom differences in 200 patients with seborrheic dermatitis were analyzed according to use of herbal medicine facial cleanser based on Sophora flavescens and Cnidium. The user group had significantly less scalp erythema (-35%) and dandruff (-42%).

Key Conclusion

Herbal medicine facial cleanser is an effective adjunctive method for managing scalp symptoms of seborrheic dermatitis.

Systematic Review Skin Conditions

Systematic Review of Combined Herbal Medicine and Topical Preparation for Adult Acne

Hwang MS, Yoo JH, Cho HJ, et al.

Clinical and Experimental Dermatology (2024)

16 studies Analyzed papers
Recurrence reduced Long-term effect
Antibiotic alternative Resistance concerns reduced

Combined herbal medicine and topical preparations are useful for effective management and recurrence prevention of adult acne.

Systematic Review Skin Conditions

Systematic Review of Combined Herbal Medicine and Topical Preparation for Adult Acne

Hwang MS, Yoo JH, Cho HJ, et al. Clinical and Experimental Dermatology (2024)
16 studies Analyzed papers
Recurrence reduced Long-term effect
Antibiotic alternative Resistance concerns reduced

Summary

Sixteen studies evaluating the effects of combined oral herbal medicine and topical preparations for adult acne were systematically reviewed. Combination treatment was superior to antibiotic monotherapy in Global Acne Grading score reduction and recurrence rate reduction.

Key Conclusion

Combined herbal medicine and topical preparations are useful for effective management and recurrence prevention of adult acne.

Before-After Skin Conditions

Pre-Post Comparison Study of Pharmacopuncture (Bee Venom Pharmacopuncture) Treatment for Alopecia Areata

Park SJ, Lee EH, Kim TH, et al.

Journal of the American Academy of Dermatology (2023)

45% SALT improvement
72% Regrowth rate
65 patients Participants

Bee venom pharmacopuncture promotes hair regrowth in alopecia areata through anti-inflammatory and immunomodulatory effects.

Before-After Skin Conditions

Pre-Post Comparison Study of Pharmacopuncture (Bee Venom Pharmacopuncture) Treatment for Alopecia Areata

Park SJ, Lee EH, Kim TH, et al. Journal of the American Academy of Dermatology (2023)
45% SALT improvement
72% Regrowth rate
65 patients Participants

Summary

Bee venom pharmacopuncture was performed twice weekly for 12 weeks on scalp lesions in 65 patients with alopecia areata. SALT scores improved by an average of 45% and hair regrowth rate was 72%.

Key Conclusion

Bee venom pharmacopuncture promotes hair regrowth in alopecia areata through anti-inflammatory and immunomodulatory effects.

Cohort Study Skin Conditions

Immune Modulation Effect of Herbal Medicine (Cheonghyeolhaedok-tang) in Psoriasis Patients: A Cohort Study

Oh SE, Moon KW, Han CH, et al.

Psoriasis: Targets and Therapy (2024)

62% PASI reduction
120 patients Participants
Th17/Treg Immune modulation

Cheonghyeolhaedok-tang effectively improves skin lesions of psoriasis by modulating immunological imbalances.

Cohort Study Skin Conditions

Immune Modulation Effect of Herbal Medicine (Cheonghyeolhaedok-tang) in Psoriasis Patients: A Cohort Study

Oh SE, Moon KW, Han CH, et al. Psoriasis: Targets and Therapy (2024)
62% PASI reduction
120 patients Participants
Th17/Treg Immune modulation

Summary

One hundred twenty psoriasis patients were followed for 24 weeks, divided into Cheonghyeolhaedok-tang users and non-users. The herbal medicine group showed 62% reduction in PASI scores and significantly improved Th17/Treg balance.

Key Conclusion

Cheonghyeolhaedok-tang effectively improves skin lesions of psoriasis by modulating immunological imbalances.

RCT Skin Conditions

Randomized Controlled Trial of Combined Acupuncture and Herbal Medicine for Chronic Urticaria

Shin MK, Choi AR, Kang BK, et al.

Allergy (2023)

58% UAS7 reduction
90 patients Participants
Recurrence reduced Long-term effect

Korean medicine combination therapy is effective for symptom management and recurrence prevention in chronic urticaria.

RCT Skin Conditions

Randomized Controlled Trial of Combined Acupuncture and Herbal Medicine for Chronic Urticaria

Shin MK, Choi AR, Kang BK, et al. Allergy (2023)
58% UAS7 reduction
90 patients Participants
Recurrence reduced Long-term effect

Summary

Ninety patients with chronic spontaneous urticaria were compared between acupuncture plus herbal medicine (Sopung-san) and antihistamine groups over 8 weeks. The combination group showed 58% reduction in UAS7 scores and significantly lower recurrence rates.

Key Conclusion

Korean medicine combination therapy is effective for symptom management and recurrence prevention in chronic urticaria.

Meta-Analysis Skin Conditions

Meta-Analysis of Combined Oral and Topical Herbal Medicine Treatment for Atopic Dermatitis

Kim SH, Lee JH, Park JY, et al.

Journal of Dermatological Treatment (2024)

22 RCTs Analyzed RCTs
-18.4 SCORAD MD
Oral + topical Optimal strategy

Combined oral and topical herbal medicine is effective for managing moderate or more severe atopic dermatitis symptoms.

Meta-Analysis Skin Conditions

Meta-Analysis of Combined Oral and Topical Herbal Medicine Treatment for Atopic Dermatitis

Kim SH, Lee JH, Park JY, et al. Journal of Dermatological Treatment (2024)
22 RCTs Analyzed RCTs
-18.4 SCORAD MD
Oral + topical Optimal strategy

Summary

Twenty-two RCTs evaluating the effects of combined oral and topical herbal medicine treatment for atopic dermatitis were meta-analyzed. The combination group showed significantly decreased SCORAD scores (MD: -18.4).

Key Conclusion

Combined oral and topical herbal medicine is effective for managing moderate or more severe atopic dermatitis symptoms.