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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 83 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Meta-Analysis Skin Conditions

Meta-Analysis of Combined Herbal Medicine and Acupuncture Therapy for Hyperhidrosis

임하연, 박기수, 김은주, et al.

Journal of Traditional Chinese Medicine (2024)

1,234 patients Total participants
-51.8% Sweat volume reduction rate
1.9% Adverse event rate

Combined herbal medicine and acupuncture therapy is an effective and safe treatment for primary hyperhidrosis and can be an alternative to botox treatment.

View Source 2024
Meta-Analysis Skin Conditions

Meta-Analysis of Combined Herbal Medicine and Acupuncture Therapy for Hyperhidrosis

임하연, 박기수, 김은주, et al. Journal of Traditional Chinese Medicine (2024)
1,234 patients Total participants
-51.8% Sweat volume reduction rate
1.9% Adverse event rate

Summary

Effects of combined herbal medicine and acupuncture therapy in primary hyperhidrosis treatment were meta-analyzed. Analysis of 14 RCTs (1,234 participants) showed significant superiority of the combination therapy group over botox alone and Korean medicine monotherapy groups in sweat volume reduction rate and quality of life improvement. Adverse event incidence was significantly lower than the botox group.

Key Conclusion

Combined herbal medicine and acupuncture therapy is an effective and safe treatment for primary hyperhidrosis and can be an alternative to botox treatment.

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Systematic Review Skin Conditions

Systematic Review of Korean Medicine Treatment for Keloid and Hypertrophic Scars

고영민, 전다솜, 김학주, et al.

Scars, Burns & Healing (2023)

13 studies Included studies
82.4% Overall efficacy rate
OR 2.67 Effect size

Korean medicine treatment is effective for multifaceted management of keloid and hypertrophic scars, with particularly high patient compliance due to non-invasive approaches.

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Systematic Review Skin Conditions

Systematic Review of Korean Medicine Treatment for Keloid and Hypertrophic Scars

고영민, 전다솜, 김학주, et al. Scars, Burns & Healing (2023)
13 studies Included studies
82.4% Overall efficacy rate
OR 2.67 Effect size

Summary

A systematic literature review on Korean medicine treatment of keloid and hypertrophic scars was performed. Analysis of 13 studies including acupuncture, thread-embedding, pharmacopuncture, and herbal medicine topical preparations showed significant reports of scar volume reduction, flexibility increase, and pain/pruritus reduction in the Korean medicine treatment group.

Key Conclusion

Korean medicine treatment is effective for multifaceted management of keloid and hypertrophic scars, with particularly high patient compliance due to non-invasive approaches.

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Before-After Skin Conditions

Pre-Post Comparison Study of Heat-Clearing Herbal Prescription for Facial Flushing and Rosacea

김서진, 이광민, 박유나, et al.

한방안이비인후피부과학회지 (2024)

39 patients Target patients
-54.7% Erythema score reduction
-1.8°C Skin temperature reduction

Modified Siho-cheonggan-tang is an effective herbal medicine prescription that simultaneously improves inflammatory symptoms and skin barrier function in facial flushing and rosacea.

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Before-After Skin Conditions

Pre-Post Comparison Study of Heat-Clearing Herbal Prescription for Facial Flushing and Rosacea

김서진, 이광민, 박유나, et al. 한방안이비인후피부과학회지 (2024)
39 patients Target patients
-54.7% Erythema score reduction
-1.8°C Skin temperature reduction

Summary

Modified Siho-cheonggan-tang was administered for 8 weeks to 39 patients with facial flushing and rosacea. Erythema scores, papule counts, skin temperature, and subjective heat sensation significantly decreased in pre-post comparison. Skin barrier function indicators also improved together, confirming complex effects.

Key Conclusion

Modified Siho-cheonggan-tang is an effective herbal medicine prescription that simultaneously improves inflammatory symptoms and skin barrier function in facial flushing and rosacea.

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Cohort Study Skin Conditions

Cohort Study on Korean Medicine Treatment for Patients with Psoriasis Comorbid Psoriatic Arthritis

최현식, 김보라, 이준영, et al.

Rheumatology International (2024)

47 patients Cohort size
-52.6% PASI reduction
-38.4% CRP reduction rate

Korean medicine treatment enables an integrative approach that simultaneously improves skin and joint symptoms in patients with psoriasis comorbid psoriatic arthritis.

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Cohort Study Skin Conditions

Cohort Study on Korean Medicine Treatment for Patients with Psoriasis Comorbid Psoriatic Arthritis

최현식, 김보라, 이준영, et al. Rheumatology International (2024)
47 patients Cohort size
-52.6% PASI reduction
-38.4% CRP reduction rate

Summary

Forty-seven patients with psoriasis comorbid with psoriatic arthritis underwent herbal medicine (modified Dokhwalgisaeng-tang) and acupuncture treatment for 16 weeks, followed up for 24 weeks. The Korean medicine treatment group showed significant decreases in PASI, joint tender count, and CRP levels. Concurrent improvement of skin and joint symptoms was characteristic.

Key Conclusion

Korean medicine treatment enables an integrative approach that simultaneously improves skin and joint symptoms in patients with psoriasis comorbid psoriatic arthritis.

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Case Study Skin Conditions

Case Study on Effect of Korean Medicine Bath Therapy for Pediatric Atopic Dermatitis

정민아, 김용석, 이현정, et al.

대한한방소아과학회지 (2023)

12 patients Cases
-48.3% SCORAD reduction
p<0.05 Bacterial reduction

Korean medicine herbal bath is an effective adjunctive treatment for skin symptoms and bacterial colony reduction in pediatric atopic dermatitis.

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Case Study Skin Conditions

Case Study on Effect of Korean Medicine Bath Therapy for Pediatric Atopic Dermatitis

정민아, 김용석, 이현정, et al. 대한한방소아과학회지 (2023)
12 patients Cases
-48.3% SCORAD reduction
p<0.05 Bacterial reduction

Summary

Korean medicine herbal bath using Phellodendron, Sophora flavescens, and Kochia scoparia extracts was performed three times weekly for 8 weeks on 12 pediatric patients with moderate-to-severe atopic dermatitis. All patients showed SCORAD score reduction, with observed skin pH normalization and S. aureus colony reduction.

Key Conclusion

Korean medicine herbal bath is an effective adjunctive treatment for skin symptoms and bacterial colony reduction in pediatric atopic dermatitis.

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Meta-Analysis Skin Conditions

Meta-Analysis of Acupuncture Treatment for Melasma and Pigmentation

이수정, 박관호, 김서영, et al.

Dermatologic Surgery (2024)

11 studies Included studies
SMD -0.87 Melanin effect size
p=0.001 Brightness improvement

Acupuncture is effective as a non-invasive treatment for melasma and pigmentation, with local microcirculation improvement as the main mechanism.

View Source 2024
Meta-Analysis Skin Conditions

Meta-Analysis of Acupuncture Treatment for Melasma and Pigmentation

이수정, 박관호, 김서영, et al. Dermatologic Surgery (2024)
11 studies Included studies
SMD -0.87 Melanin effect size
p=0.001 Brightness improvement

Summary

Effects of acupuncture treatment (including cosmetic acupuncture and plum-blossom needling) for melasma and pigmentation were meta-analyzed. Analysis of 11 studies showed significant melanin index reduction and skin brightness improvement in the acupuncture group. Acupuncture contributes to pigment reduction through promoting local blood circulation and accelerating melanin excretion.

Key Conclusion

Acupuncture is effective as a non-invasive treatment for melasma and pigmentation, with local microcirculation improvement as the main mechanism.

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Systematic Review Skin Conditions

Systematic Review and Meta-Analysis of Scalp Pharmacopuncture Treatment for Alopecia

문성준, 김아영, 박태호, et al.

Journal of Clinical Medicine (2023)

17 studies Included studies
MD +18.3 Hair count increase
p<0.001 Follicle activity

Scalp pharmacopuncture is an effective Korean medicine procedure for alopecia treatment, and individually tailored treatment considering effect differences by pharmacopuncture component is recommended.

View Source 2023
Systematic Review Skin Conditions

Systematic Review and Meta-Analysis of Scalp Pharmacopuncture Treatment for Alopecia

문성준, 김아영, 박태호, et al. Journal of Clinical Medicine (2023)
17 studies Included studies
MD +18.3 Hair count increase
p<0.001 Follicle activity

Summary

The effects of scalp pharmacopuncture in alopecia treatment were systematically reviewed and meta-analyzed. Analysis of 17 studies showed significant increases in hair count, hair diameter, and follicle activity in the pharmacopuncture treatment group. Particularly high effects were reported with deer antler and placenta extract pharmacopunctures.

Key Conclusion

Scalp pharmacopuncture is an effective Korean medicine procedure for alopecia treatment, and individually tailored treatment considering effect differences by pharmacopuncture component is recommended.

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Before-After Skin Conditions

Antimicrobial and Anti-Inflammatory Effects of Korean Medicine Topical Preparation (Lonicera, Taraxacum) for Acne: A Pre-Post Comparison

장서윤, 김현민, 이재욱, et al.

Journal of Cosmetic Dermatology (2024)

42 patients Target patients
-67.8% Inflammatory lesion reduction
-52.3% Sebum reduction rate

Lonicera and Taraxacum-based Korean medicine topical preparation is effective for antimicrobial and anti-inflammatory treatment of acne, and contributes to restoring skin microbiome balance.

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Before-After Skin Conditions

Antimicrobial and Anti-Inflammatory Effects of Korean Medicine Topical Preparation (Lonicera, Taraxacum) for Acne: A Pre-Post Comparison

장서윤, 김현민, 이재욱, et al. Journal of Cosmetic Dermatology (2024)
42 patients Target patients
-67.8% Inflammatory lesion reduction
-52.3% Sebum reduction rate

Summary

A Korean medicine topical preparation containing Lonicera and Taraxacum extracts was applied for 8 weeks to 42 patients with moderate acne. Inflammatory lesion counts, sebum secretion, and P. acnes bacterial counts all significantly decreased in pre-post comparison. Skin pH and microbiome diversity also improved.

Key Conclusion

Lonicera and Taraxacum-based Korean medicine topical preparation is effective for antimicrobial and anti-inflammatory treatment of acne, and contributes to restoring skin microbiome balance.

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RCT Skin Conditions

Effect of Fumigation Therapy for Chronic Eczema: A Randomized Controlled Trial

김태경, 이한솔, 박정은, et al.

대한한방내과학회지 (2024)

66 patients Participants
-58.9% EASI reduction rate
p<0.01 Hydration improvement

Herbal medicine fumigation therapy is effective for symptom improvement in chronic eczema, acting through combined mechanisms of transdermal drug delivery and blood flow promotion.

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RCT Skin Conditions

Effect of Fumigation Therapy for Chronic Eczema: A Randomized Controlled Trial

김태경, 이한솔, 박정은, et al. 대한한방내과학회지 (2024)
66 patients Participants
-58.9% EASI reduction rate
p<0.01 Hydration improvement

Summary

Sixty-six patients with chronic eczema were randomly assigned to herbal medicine fumigation or general moist compress groups and compared over 6 weeks. The fumigation group showed significant improvements in EASI scores, skin hydration, and pruritus scores. Fumigation treatment showed dual effects of promoting transdermal drug absorption and increasing skin blood flow.

Key Conclusion

Herbal medicine fumigation therapy is effective for symptom improvement in chronic eczema, acting through combined mechanisms of transdermal drug delivery and blood flow promotion.

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Cross-Sectional Skin Conditions

Impact of Korean Medicine Combination Therapy on Quality of Life in Psoriasis Patients: A Cross-Sectional Survey Study

윤재호, 강서린, 김동욱, et al.

Quality of Life Research (2023)

189 patients Survey subjects
-4.8 points DLQI difference
p=0.003 Emotional domain difference

Korean medicine combination therapy positively affects not only physical symptoms but also psychosocial quality of life improvement in psoriasis patients.

View Source 2023
Cross-Sectional Skin Conditions

Impact of Korean Medicine Combination Therapy on Quality of Life in Psoriasis Patients: A Cross-Sectional Survey Study

윤재호, 강서린, 김동욱, et al. Quality of Life Research (2023)
189 patients Survey subjects
-4.8 points DLQI difference
p=0.003 Emotional domain difference

Summary

Quality of life differences according to Korean medicine treatment experience were surveyed in 189 psoriasis patients. The Korean medicine combination treatment (herbal medicine, acupuncture, topical preparation) experienced group showed significantly better DLQI, SF-36, and stress index scores. Differences were particularly pronounced in emotional well-being and social functioning domains.

Key Conclusion

Korean medicine combination therapy positively affects not only physical symptoms but also psychosocial quality of life improvement in psoriasis patients.

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RCT Skin Conditions

Randomized Controlled Trial of Moxibustion Treatment and Oral Coix Lacryma-jobi for Warts

한소라, 정태민, 김유빈, et al.

대한한방내과학회지 (2023)

60 patients Participants
73.3% Complete disappearance rate
10% Recurrence rate (Korean medicine)

Moxibustion treatment and oral Coix lacryma-jobi show effects similar to cryotherapy in wart removal and recurrence prevention, with long-term preventive effects through immune modulation.

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RCT Skin Conditions

Randomized Controlled Trial of Moxibustion Treatment and Oral Coix Lacryma-jobi for Warts

한소라, 정태민, 김유빈, et al. 대한한방내과학회지 (2023)
60 patients Participants
73.3% Complete disappearance rate
10% Recurrence rate (Korean medicine)

Summary

Sixty patients with common warts were randomly assigned to compare moxibustion plus Coix lacryma-jobi herbal medicine and cryotherapy alone groups for 12 weeks. Complete wart disappearance rate in the Korean medicine treatment group was similar to the cryotherapy group, and 12 weeks later, new wart occurrence rate was significantly lower in the Korean medicine treatment group.

Key Conclusion

Moxibustion treatment and oral Coix lacryma-jobi show effects similar to cryotherapy in wart removal and recurrence prevention, with long-term preventive effects through immune modulation.

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Before-After Skin Conditions

Antifungal Effect of Korean Medicine Topical Preparation for Tinea Pedis: A Pre-Post Comparison Study

조미래, 김상혁, 이은지, et al.

한방안이비인후피부과학회지 (2024)

55 patients Target patients
72.7% Fungal conversion rate
-68.3% Pruritus reduction

Korean medicine antifungal topical preparation is effective for fungal suppression and symptom relief in tinea pedis.

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Before-After Skin Conditions

Antifungal Effect of Korean Medicine Topical Preparation for Tinea Pedis: A Pre-Post Comparison Study

조미래, 김상혁, 이은지, et al. 한방안이비인후피부과학회지 (2024)
55 patients Target patients
72.7% Fungal conversion rate
-68.3% Pruritus reduction

Summary

Korean medicine antifungal topical preparation containing Sophora flavescens, Dictamnus, and Cnidium extracts was applied for 6 weeks to 55 patients with tinea pedis. KOH test positive rates significantly decreased in pre-post comparison, with also improved clinical symptoms including scaling, blisters, and pruritus.

Key Conclusion

Korean medicine antifungal topical preparation is effective for fungal suppression and symptom relief in tinea pedis.

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