금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
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Total 71 papers

Systematic Review Respiratory Conditions

Effect of Early Galgeun-tang Administration on Initial Cold Symptoms: A Systematic Review

김동현, 박수진, 이재훈, et al.

대한한방내과학회지 (2024)

2.3 days Symptom duration reduction
12 studies Analyzed studies
87% Symptom improvement rate

Early Galgeun-tang administration is effective for rapid cold symptom relief and reduced illness duration, with a favorable safety profile.

Systematic Review Respiratory Conditions

Effect of Early Galgeun-tang Administration on Initial Cold Symptoms: A Systematic Review

김동현, 박수진, 이재훈, et al. 대한한방내과학회지 (2024)
2.3 days Symptom duration reduction
12 studies Analyzed studies
87% Symptom improvement rate

Summary

Twelve studies on the effect of Galgeun-tang administration within 48 hours of cold onset were systematically analyzed. The early administration group showed an average 2.3-day reduction in symptom duration, with significantly faster fever resolution time. Side effect reports were limited to only 3 cases of mild gastrointestinal disturbance.

Key Conclusion

Early Galgeun-tang administration is effective for rapid cold symptom relief and reduced illness duration, with a favorable safety profile.

RCT Respiratory Conditions

Effect of Korean Medicine Smoking Cessation Program: A Randomized Controlled Trial of Combined Auricular Acupuncture and Herbal Medicine

Shin SM, Park HJ, Lim BV, et al.

Nicotine & Tobacco Research (2024)

48% Smoking cessation success rate
100 patients Participants
12 weeks Program duration

Combined auricular acupuncture and herbal medicine smoking cessation program shows higher smoking cessation success rates than existing nicotine replacement therapy.

RCT Respiratory Conditions

Effect of Korean Medicine Smoking Cessation Program: A Randomized Controlled Trial of Combined Auricular Acupuncture and Herbal Medicine

Shin SM, Park HJ, Lim BV, et al. Nicotine & Tobacco Research (2024)
48% Smoking cessation success rate
100 patients Participants
12 weeks Program duration

Summary

One hundred smokers with intention to quit were divided into auricular acupuncture plus herbal medicine smoking cessation program and nicotine patch groups and compared over 12 weeks. The 12-week smoking cessation success rate of the Korean medicine program group was 48%, significantly higher than the nicotine patch group at 35%.

Key Conclusion

Combined auricular acupuncture and herbal medicine smoking cessation program shows higher smoking cessation success rates than existing nicotine replacement therapy.

Cohort Study Respiratory Conditions

Antibiotic Use Reduction Effect of Herbal Medicine Combination Treatment in Bronchitis Patients: A Retrospective Analysis

Lim HY, Song GJ, et al.

Antibiotics (2023)

500 patients Analysis population
38% vs 62% Antibiotic prescription rate
p<0.001 Statistical significance

Herbal medicine combination treatment contributes to reducing unnecessary antibiotic use in bronchitis patients.

Cohort Study Respiratory Conditions

Antibiotic Use Reduction Effect of Herbal Medicine Combination Treatment in Bronchitis Patients: A Retrospective Analysis

Lim HY, Song GJ, et al. Antibiotics (2023)
500 patients Analysis population
38% vs 62% Antibiotic prescription rate
p<0.001 Statistical significance

Summary

Medical records of 500 patients with acute bronchitis were retrospectively analyzed to compare antibiotic prescription rates between herbal medicine combination and Western medicine alone groups. The herbal medicine combination group had significantly lower antibiotic prescription rates.

Key Conclusion

Herbal medicine combination treatment contributes to reducing unnecessary antibiotic use in bronchitis patients.

Cross-Sectional Respiratory Conditions

Korean Medicine Treatment Satisfaction and Compliance in COPD Patients: A Multicenter Survey Study

Yang SH, Cho BN, et al.

Patient Preference and Adherence (2024)

300 patients Respondents
82% Satisfaction
8 centers Participating centers

Korean medicine treatment satisfaction in COPD patients is high, and strategies for improving compliance are needed.

Cross-Sectional Respiratory Conditions

Korean Medicine Treatment Satisfaction and Compliance in COPD Patients: A Multicenter Survey Study

Yang SH, Cho BN, et al. Patient Preference and Adherence (2024)
300 patients Respondents
82% Satisfaction
8 centers Participating centers

Summary

A survey was conducted at 8 Korean medicine hospitals on treatment satisfaction, compliance, and quality of life of 300 patients receiving Korean medicine treatment for COPD. Overall satisfaction was 82% and treatment compliance was 76%.

Key Conclusion

Korean medicine treatment satisfaction in COPD patients is high, and strategies for improving compliance are needed.

RCT Respiratory Conditions

Effect of Cheongpyesagan-tang in Chronic Cough Patients: A Randomized Controlled Trial

Choi YS, Kim HM, et al.

Respiratory Medicine (2023)

70 patients Participants
55% Cough frequency reduction
8 weeks Treatment duration

Cheongpyesagan-tang is effective in reducing cough frequency and severity in patients with unexplained chronic cough.

RCT Respiratory Conditions

Effect of Cheongpyesagan-tang in Chronic Cough Patients: A Randomized Controlled Trial

Choi YS, Kim HM, et al. Respiratory Medicine (2023)
70 patients Participants
55% Cough frequency reduction
8 weeks Treatment duration

Summary

Seventy patients with unexplained chronic cough were randomly assigned to a Cheongpyesagan-tang or placebo group and compared over 8 weeks. The herbal medicine group showed significant reductions in 24-hour cough frequency and cough VAS.

Key Conclusion

Cheongpyesagan-tang is effective in reducing cough frequency and severity in patients with unexplained chronic cough.

RCT Respiratory Conditions

Synergistic Effect of Korean Medicine Breathing Exercises and Herbal Medicine for Pulmonary Function Improvement: An RCT

Ahn MH, Jung SK, et al.

Journal of Cardiopulmonary Rehabilitation and Prevention (2023)

100 patients Participants
3-arm comparison Study design
12 weeks Treatment duration

Combination of Korean medicine breathing exercises and herbal medicine shows synergistic effects on pulmonary function improvement.

RCT Respiratory Conditions

Synergistic Effect of Korean Medicine Breathing Exercises and Herbal Medicine for Pulmonary Function Improvement: An RCT

Ahn MH, Jung SK, et al. Journal of Cardiopulmonary Rehabilitation and Prevention (2023)
100 patients Participants
3-arm comparison Study design
12 weeks Treatment duration

Summary

One hundred patients with reduced pulmonary function were randomly assigned to Korean medicine breathing exercise plus herbal medicine, breathing exercise alone, or control groups and compared over 12 weeks. The combination group showed the greatest improvements in FVC, FEV1, and MIP.

Key Conclusion

Combination of Korean medicine breathing exercises and herbal medicine shows synergistic effects on pulmonary function improvement.

Narrative Review Respiratory Conditions

Korean Medicine Treatment for Post-Infectious Chronic Cough: A Literature Review

Son KJ, Park DH, et al.

Pulmonary Pharmacology & Therapeutics (2022)

25 studies Reviewed papers
3 types Major mechanisms
High Clinical applicability

Korean medicine treatment is effective in modulating cough reflex hypersensitivity and airway inflammation in post-infectious chronic cough.

Narrative Review Respiratory Conditions

Korean Medicine Treatment for Post-Infectious Chronic Cough: A Literature Review

Son KJ, Park DH, et al. Pulmonary Pharmacology & Therapeutics (2022)
25 studies Reviewed papers
3 types Major mechanisms
High Clinical applicability

Summary

Twenty-five studies on the effects and mechanisms of Korean medicine treatment for post-infectious chronic cough were comprehensively reviewed.

Key Conclusion

Korean medicine treatment is effective in modulating cough reflex hypersensitivity and airway inflammation in post-infectious chronic cough.

Case Study Respiratory Conditions

Korean Medicine Treatment Experience for Asthma-COPD Overlap Syndrome: A Case Report

Kang TY, Shin BK, et al.

Journal of Korean Medicine (2020)

5 patients Cases
60% Inhaler reduction success
6 months Follow-up period

Korean medicine treatment can contribute adjunctively to symptom management and inhaler reduction in ACO patients.

Case Study Respiratory Conditions

Korean Medicine Treatment Experience for Asthma-COPD Overlap Syndrome: A Case Report

Kang TY, Shin BK, et al. Journal of Korean Medicine (2020)
5 patients Cases
60% Inhaler reduction success
6 months Follow-up period

Summary

Pattern-differentiated herbal medicine and acupuncture were performed in 5 patients with asthma-COPD overlap syndrome (ACO). Three patients successfully reduced inhaler use and stabilized pulmonary function.

Key Conclusion

Korean medicine treatment can contribute adjunctively to symptom management and inhaler reduction in ACO patients.

RCT Respiratory Conditions

Effect of Korean Medicine Preventive Treatment on Particulate Matter Exposure and Respiratory Symptoms

Go SH, Lee MJ, et al.

Environmental Health Perspectives (2024)

200 patients Participants
41% Symptom occurrence reduction
3 months Observation period

Korean medicine preventive treatment is effective in reducing the occurrence of particulate matter-related respiratory symptoms.

RCT Respiratory Conditions

Effect of Korean Medicine Preventive Treatment on Particulate Matter Exposure and Respiratory Symptoms

Go SH, Lee MJ, et al. Environmental Health Perspectives (2024)
200 patients Participants
41% Symptom occurrence reduction
3 months Observation period

Summary

Two hundred residents of high particulate matter exposure areas were divided into a Korean medicine preventive treatment group and a control group, and respiratory symptom occurrence was compared during 3 months of high concentration periods. The Korean medicine treatment group had significantly lower respiratory symptom occurrence rates.

Key Conclusion

Korean medicine preventive treatment is effective in reducing the occurrence of particulate matter-related respiratory symptoms.

Meta-Analysis Respiratory Conditions

Meta-Analysis of Pharmacopuncture for Respiratory Diseases

Woo BH, Kim SR, Patel A, et al.

Journal of Pharmacopuncture (2025)

8 studies Included studies
620 patients Total participants
p<0.05 Pulmonary function improvement

Pharmacopuncture is an effective adjunctive intervention for respiratory disease management.

Meta-Analysis Respiratory Conditions

Meta-Analysis of Pharmacopuncture for Respiratory Diseases

Woo BH, Kim SR, Patel A, et al. Journal of Pharmacopuncture (2025)
8 studies Included studies
620 patients Total participants
p<0.05 Pulmonary function improvement

Summary

Eight RCTs (total 620 patients) evaluating pharmacopuncture for respiratory diseases (asthma, COPD, chronic cough) were meta-analyzed. The pharmacopuncture group showed significant improvements in symptom scores and pulmonary function.

Key Conclusion

Pharmacopuncture is an effective adjunctive intervention for respiratory disease management.

Case Study Respiratory Conditions

Effect of Korean Medicine Treatment in Patients with Bronchiectasis: A Case Series

Jeon HJ, Cho MK, et al.

Respiratory Medicine Case Reports (2021)

7 patients Cases
57% Sputum reduction
12 weeks Treatment duration

Korean medicine treatment can be utilized adjunctively for symptom management in bronchiectasis patients.

Case Study Respiratory Conditions

Effect of Korean Medicine Treatment in Patients with Bronchiectasis: A Case Series

Jeon HJ, Cho MK, et al. Respiratory Medicine Case Reports (2021)
7 patients Cases
57% Sputum reduction
12 weeks Treatment duration

Summary

Herbal medicine and acupuncture were performed for 12 weeks on 7 patients with bronchiectasis. Decreased sputum volume, reduced acute exacerbation frequency, and improved SGRQ scores were observed.

Key Conclusion

Korean medicine treatment can be utilized adjunctively for symptom management in bronchiectasis patients.

Systematic Review Respiratory Conditions

Antioxidant and Anti-Inflammatory Effects of Herbal Medicine in COPD: A Systematic Review

Moon SY, Kim GH, Wang Z, et al.

Oxidative Medicine and Cellular Longevity (2023)

28 studies Included studies
20 studies Positive results
Moderate-High Evidence level

Herbal medicine is effective in regulating oxidative stress and systemic inflammation in COPD.

Systematic Review Respiratory Conditions

Antioxidant and Anti-Inflammatory Effects of Herbal Medicine in COPD: A Systematic Review

Moon SY, Kim GH, Wang Z, et al. Oxidative Medicine and Cellular Longevity (2023)
28 studies Included studies
20 studies Positive results
Moderate-High Evidence level

Summary

Twenty-eight basic and clinical studies on antioxidant and anti-inflammatory effects of herbal medicine for COPD were systematically reviewed. Positive results were reported on various indicators including SOD increase, MDA reduction, and CRP reduction.

Key Conclusion

Herbal medicine is effective in regulating oxidative stress and systemic inflammation in COPD.