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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 71 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Cohort Study Respiratory Conditions

Pulmonary Rehabilitation Effect of Combined Acupuncture and Doin Exercise for Long COVID Dyspnea: A Cohort Study

조민서, 박현우, 김예은, et al.

Respiratory Medicine (2023)

67 m 6-min walk distance increase
136 patients Study population
12 weeks Program duration

Korean medicine pulmonary rehabilitation based on acupuncture and Doin exercise shows equivalent or superior effects to standard pulmonary rehabilitation in exercise capacity recovery and symptom improvement of long COVID dyspnea patients.

View Source 2023
Cohort Study Respiratory Conditions

Pulmonary Rehabilitation Effect of Combined Acupuncture and Doin Exercise for Long COVID Dyspnea: A Cohort Study

조민서, 박현우, 김예은, et al. Respiratory Medicine (2023)
67 m 6-min walk distance increase
136 patients Study population
12 weeks Program duration

Summary

A prospective cohort study comparing a 12-week Korean medicine pulmonary rehabilitation program including acupuncture and Doin exercise versus a standard pulmonary rehabilitation program in 136 patients with persistent dyspnea due to COVID-19 sequelae. The Korean medicine pulmonary rehabilitation group showed average 67 m increase in 6-minute walk distance, with significantly improved mMRC dyspnea scale.

Key Conclusion

Korean medicine pulmonary rehabilitation based on acupuncture and Doin exercise shows equivalent or superior effects to standard pulmonary rehabilitation in exercise capacity recovery and symptom improvement of long COVID dyspnea patients.

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Cross-Sectional Respiratory Conditions

Effect of Acupuncture for Cognitive Decline and Respiratory Symptoms in Long COVID: A Cross-Sectional Study

김지훈, 이해인, 정소현, et al.

BMC Complementary Medicine and Therapies (2024)

2.8 points MoCA score improvement
92 patients Study population
43% Respiratory symptom improvement

Acupuncture can be utilized as a multifunctional treatment that simultaneously improves cognitive decline and respiratory symptoms in long COVID patients.

View Source 2024
Cross-Sectional Respiratory Conditions

Effect of Acupuncture for Cognitive Decline and Respiratory Symptoms in Long COVID: A Cross-Sectional Study

김지훈, 이해인, 정소현, et al. BMC Complementary Medicine and Therapies (2024)
2.8 points MoCA score improvement
92 patients Study population
43% Respiratory symptom improvement

Summary

A cross-sectional study analyzing symptom changes before and after acupuncture treatment (GV20, Sasinchong, BL13, LU1) in 92 patients with comorbid cognitive decline and respiratory symptoms due to COVID-19 sequelae. After acupuncture treatment, MoCA (Cognitive Function Assessment) scores improved by an average of 2.8 points, with concurrent improvements in cough and dyspnea.

Key Conclusion

Acupuncture can be utilized as a multifunctional treatment that simultaneously improves cognitive decline and respiratory symptoms in long COVID patients.

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Narrative Review Respiratory Conditions

Narrative Review on Effects of Korean Medicine Fumigation Treatment in Asthma Patients

박서영, 김규현, 이수민, et al.

대한외관과학회지 (2023)

14 studies Reviewed papers
3 prescriptions Major fumigation prescriptions
10 years Review period

Korean medicine fumigation treatment may contribute to bronchial dilation and airway hyperresponsiveness alleviation as an adjunctive treatment for asthma, and standardized protocol development is needed.

View Source 2023
Narrative Review Respiratory Conditions

Narrative Review on Effects of Korean Medicine Fumigation Treatment in Asthma Patients

박서영, 김규현, 이수민, et al. 대한외관과학회지 (2023)
14 studies Reviewed papers
3 prescriptions Major fumigation prescriptions
10 years Review period

Summary

A narrative review comprehensively examining mechanisms, clinical evidence, and treatment protocols of Korean medicine fumigation treatment (medicinal vapor inhalation) for asthma patients. Fumigation prescriptions including Ephedra, Asarum, and Sinapis showed effectiveness in bronchial dilation and mucus expectoration promotion.

Key Conclusion

Korean medicine fumigation treatment may contribute to bronchial dilation and airway hyperresponsiveness alleviation as an adjunctive treatment for asthma, and standardized protocol development is needed.

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Before-After Respiratory Conditions

Effect of Cheongpye-tang for Acute Exacerbation of Chronic Bronchitis: A Pre-Post Comparison Study

한지원, 김영호, 이채은, et al.

동의생리병리학회지 (2024)

72% Sputum reduction rate
64 patients Study population
10 days Treatment duration

Cheongpye-tang is a useful herbal medicine prescription that assists rapid symptom recovery in acute exacerbation of chronic bronchitis through anti-inflammatory and expectorant effects.

View Source 2024
Before-After Respiratory Conditions

Effect of Cheongpye-tang for Acute Exacerbation of Chronic Bronchitis: A Pre-Post Comparison Study

한지원, 김영호, 이채은, et al. 동의생리병리학회지 (2024)
72% Sputum reduction rate
64 patients Study population
10 days Treatment duration

Summary

A pre-post comparison study administering Cheongpye-tang for 10 days to 64 patients with acute exacerbation of chronic bronchitis. After treatment, sputum output decreased by 72%, with significant improvements in both cough VAS and CRP levels. Symptom recovery was faster than historical controls treated with antibiotics alone.

Key Conclusion

Cheongpye-tang is a useful herbal medicine prescription that assists rapid symptom recovery in acute exacerbation of chronic bronchitis through anti-inflammatory and expectorant effects.

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Case Study Respiratory Conditions

Expectorant Effect of Pharmacopuncture for COPD Patients with Sputum: A Case Series

오현석, 김은비, 정재원, et al.

대한약침학회지 (2024)

47% Sputum volume reduction
10 patients Number of cases
8 weeks Treatment duration

Pharmacopuncture effectively reduces excessive sputum in COPD patients and can be utilized as an adjunctive means for airway hygiene management.

View Source 2024
Case Study Respiratory Conditions

Expectorant Effect of Pharmacopuncture for COPD Patients with Sputum: A Case Series

오현석, 김은비, 정재원, et al. 대한약침학회지 (2024)
47% Sputum volume reduction
10 patients Number of cases
8 weeks Treatment duration

Summary

A case series performing placenta-Astragalus pharmacopuncture at BL13 and CV22 for 8 weeks in 10 COPD patients with large amounts of sputum as main symptom. After treatment, daily sputum output decreased by an average of 47%, with improved sputum color and viscosity, and enhanced airway hygiene.

Key Conclusion

Pharmacopuncture effectively reduces excessive sputum in COPD patients and can be utilized as an adjunctive means for airway hygiene management.

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Narrative Review Respiratory Conditions

Recent Research Trends in Korean Medicine Treatment for Cold: A Narrative Review

정유진, 김동원, 이하영, et al.

대한한의학회지 (2023)

32 studies Reviewed papers
6 prescriptions Major prescription analysis
10 years Review period

Evidence for Korean medicine treatment of cold is gradually accumulating, and development of standardized clinical guidelines is a future challenge.

View Source 2023
Narrative Review Respiratory Conditions

Recent Research Trends in Korean Medicine Treatment for Cold: A Narrative Review

정유진, 김동원, 이하영, et al. 대한한의학회지 (2023)
32 studies Reviewed papers
6 prescriptions Major prescription analysis
10 years Review period

Summary

A narrative review comprehensively examining clinical research trends in Korean medicine treatment for cold over the past 10 years. Evidence levels of major prescriptions including Galgeun-tang, Eungyo-san, and Ssanghwa-tang were evaluated, and adjunctive roles of non-pharmacological treatments such as acupuncture, cupping, and moxibustion were analyzed.

Key Conclusion

Evidence for Korean medicine treatment of cold is gradually accumulating, and development of standardized clinical guidelines is a future challenge.

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Cohort Study Respiratory Conditions

Safety and Efficacy of Long-Term Bopye-tang Administration in Elderly with Reduced Pulmonary Function: A Cohort Study

조수현, 김영진, 박지수, et al.

대한한방내과학회지 (2024)

8.7% FEV1 improvement
88 patients Study population
24 weeks Treatment duration

Long-term Bopye-tang administration is a safe Korean medicine treatment that slows the progression of reduced pulmonary function in the elderly and improves systemic physical strength.

View Source 2024
Cohort Study Respiratory Conditions

Safety and Efficacy of Long-Term Bopye-tang Administration in Elderly with Reduced Pulmonary Function: A Cohort Study

조수현, 김영진, 박지수, et al. 대한한방내과학회지 (2024)
8.7% FEV1 improvement
88 patients Study population
24 weeks Treatment duration

Summary

A prospective cohort study administering and observing Bopye-tang for 24 weeks in 88 elderly aged 65 or older with reduced pulmonary function (FEV1 predicted 60-80%). After treatment, FEV1 improved by an average of 8.7%, with reduced COPD acute exacerbations and improved overall physical strength indicators.

Key Conclusion

Long-term Bopye-tang administration is a safe Korean medicine treatment that slows the progression of reduced pulmonary function in the elderly and improves systemic physical strength.

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RCT Respiratory Conditions

Effect of Acupuncture for Patients with Anxiety Disorder Accompanied by Dyspnea: A Randomized Controlled Trial

김하은, 정민규, 이승아, et al.

Journal of Acupuncture and Meridian Studies (2023)

1.4 points mMRC scale improvement
76 patients Study population
48% BAI score reduction

Acupuncture is an effective non-pharmacological treatment that simultaneously improves both symptoms in patients with comorbid dyspnea and anxiety.

View Source 2023
RCT Respiratory Conditions

Effect of Acupuncture for Patients with Anxiety Disorder Accompanied by Dyspnea: A Randomized Controlled Trial

김하은, 정민규, 이승아, et al. Journal of Acupuncture and Meridian Studies (2023)
1.4 points mMRC scale improvement
76 patients Study population
48% BAI score reduction

Summary

A randomized controlled trial comparing acupuncture at PC6, HT7, BL13 versus sham acupuncture in 76 patients with comorbid dyspnea and anxiety disorder. After 6 weeks, the acupuncture group showed significantly improved mMRC dyspnea scale, with concurrent reduction in BAI (anxiety scale).

Key Conclusion

Acupuncture is an effective non-pharmacological treatment that simultaneously improves both symptoms in patients with comorbid dyspnea and anxiety.

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Before-After Respiratory Conditions

Effect of Combined Acupuncture and Moxibustion for Post-Pleurisy Chest Pain: A Pre-Post Comparison Study

김동혁, 조은솔, 이정현, et al.

대한침구의학회지 (2023)

62.3% Chest pain NRS reduction rate
42 patients Study population
6 weeks Treatment duration

Combined acupuncture and moxibustion can be utilized as an effective non-pharmacological management method for residual chest pain after pleurisy.

View Source 2023
Before-After Respiratory Conditions

Effect of Combined Acupuncture and Moxibustion for Post-Pleurisy Chest Pain: A Pre-Post Comparison Study

김동혁, 조은솔, 이정현, et al. 대한침구의학회지 (2023)
62.3% Chest pain NRS reduction rate
42 patients Study population
6 weeks Treatment duration

Summary

A pre-post comparison study performing acupuncture (LR14, LR13, LU1) and moxibustion for 6 weeks in 42 patients with residual chest pain persisting more than 4 weeks after pleurisy. Chest pain NRS decreased from 6.1 before treatment to 2.3 after treatment, with significantly alleviated deep breathing pain.

Key Conclusion

Combined acupuncture and moxibustion can be utilized as an effective non-pharmacological management method for residual chest pain after pleurisy.

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Systematic Review Respiratory Conditions

Protective Effect of Cheongpyesagan-tang on Respiratory Inflammation from Particulate Matter Exposure: A Systematic Review

박준서, 김유나, 이도경, et al.

Environmental Health and Preventive Medicine (2024)

10 studies Analyzed studies
35% Symptom occurrence reduction
PM2.5 Main pollutant

Cheongpyesagan-tang shows preventive and therapeutic effects against respiratory inflammation from particulate matter and can be utilized for environmental respiratory disease management.

View Source 2024
Systematic Review Respiratory Conditions

Protective Effect of Cheongpyesagan-tang on Respiratory Inflammation from Particulate Matter Exposure: A Systematic Review

박준서, 김유나, 이도경, et al. Environmental Health and Preventive Medicine (2024)
10 studies Analyzed studies
35% Symptom occurrence reduction
PM2.5 Main pollutant

Summary

Ten preclinical and clinical studies evaluating the protective effect of Cheongpyesagan-tang on respiratory inflammatory response to particulate matter (PM2.5/PM10) exposure were systematically reviewed. In clinical studies, respiratory symptom occurrence rates in the herbal medicine group during high particulate matter concentration periods were significantly lower.

Key Conclusion

Cheongpyesagan-tang shows preventive and therapeutic effects against respiratory inflammation from particulate matter and can be utilized for environmental respiratory disease management.

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RCT Respiratory Conditions

Immune Modulation Effect of Okbyungpung-san in High-Risk Groups for Environmental Respiratory Diseases: A Randomized Controlled Trial

이서준, 김채원, 정승호, et al.

Phytotherapy Research (2023)

52% Infection frequency reduction
96 patients Study population
NK cell increase Immune indicator improvement

Okbyungpung-san can be utilized as a preventive herbal medicine that strengthens immune function and reduces infection frequency in high-risk groups for environmental respiratory diseases.

View Source 2023
RCT Respiratory Conditions

Immune Modulation Effect of Okbyungpung-san in High-Risk Groups for Environmental Respiratory Diseases: A Randomized Controlled Trial

이서준, 김채원, 정승호, et al. Phytotherapy Research (2023)
52% Infection frequency reduction
96 patients Study population
NK cell increase Immune indicator improvement

Summary

A comparison of Okbyungpung-san 12-week administration versus placebo in 96 residents of high air pollution exposure areas with history of recurrent upper respiratory infections. The Okbyungpung-san group showed 52% reduction in upper respiratory infection occurrence, with significant increases in NK cell activity and secretory IgA levels.

Key Conclusion

Okbyungpung-san can be utilized as a preventive herbal medicine that strengthens immune function and reduces infection frequency in high-risk groups for environmental respiratory diseases.

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Before-After Respiratory Conditions

Antipyretic and Expectorant Effects of Eungyo-san for Acute Bronchitis: A Pre-Post Comparison Study

최준영, 한소희, 이민재, et al.

동의생리병리학회지 (2024)

1.8 days Fever duration reduction
58 patients Study population
63% Sputum viscosity reduction

Eungyo-san can be utilized as an effective antipyretic and expectorant for initial treatment of acute bronchitis and may contribute to reducing antibiotic prescription.

View Source 2024
Before-After Respiratory Conditions

Antipyretic and Expectorant Effects of Eungyo-san for Acute Bronchitis: A Pre-Post Comparison Study

최준영, 한소희, 이민재, et al. 동의생리병리학회지 (2024)
1.8 days Fever duration reduction
58 patients Study population
63% Sputum viscosity reduction

Summary

A pre-post comparison study administering Eungyo-san for 7 days to 58 adult patients diagnosed with acute bronchitis. Fever duration was shortened by an average of 1.8 days compared to natural course in control literature, with significantly reduced sputum volume and viscosity.

Key Conclusion

Eungyo-san can be utilized as an effective antipyretic and expectorant for initial treatment of acute bronchitis and may contribute to reducing antibiotic prescription.

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