금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
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Total 91 papers

Case Study Pediatric / Adolescent Care

Case Report of 12 Children with Tic Disorder Treated with Korean Medicine: Modified Eokgan-san-Gajinpibanha

Moon HY, Cho DH, et al.

대한한방소아과학회지 (2024)

44.7% YGTSS reduction rate
12 cases Number of cases
16 weeks Follow-up period

After combined herbal medicine and acupuncture treatment, total YGTSS scores decreased by an average of 44.7%, with greater improvement in motor tics than vocal tics. No adverse effects were observed in any of the 12 cases.

Case Study Pediatric / Adolescent Care

Case Report of 12 Children with Tic Disorder Treated with Korean Medicine: Modified Eokgan-san-Gajinpibanha

Moon HY, Cho DH, et al. 대한한방소아과학회지 (2024)
44.7% YGTSS reduction rate
12 cases Number of cases
16 weeks Follow-up period

Summary

A report on 12 children with tic disorder treated with Eokgan-san-Gajinpibanha and acupuncture (GV20, GB20, LI4). YGTSS scores and tic frequency changes were followed over 16 weeks.

Key Conclusion

After combined herbal medicine and acupuncture treatment, total YGTSS scores decreased by an average of 44.7%, with greater improvement in motor tics than vocal tics. No adverse effects were observed in any of the 12 cases.

Narrative Review Pediatric / Adolescent Care

Recent Literature Review on Korean Medicine Treatment for Tourette Syndrome in Children and Adolescents

Kang JE, Park MH, et al.

대한한방신경정신과학회지 (2023)

28 studies Reviewed studies
Effect size 0.72 Standardized mean difference
Adverse events 2.1% Adverse event incidence

Combination of herbal medicine (Cheonmagudeung-eum, modified Eokgan-san) and acupuncture treatment was most effective in alleviating Tourette syndrome symptoms, with fewer side effects than Western medication, making it suitable for long-term treatment.

Narrative Review Pediatric / Adolescent Care

Recent Literature Review on Korean Medicine Treatment for Tourette Syndrome in Children and Adolescents

Kang JE, Park MH, et al. 대한한방신경정신과학회지 (2023)
28 studies Reviewed studies
Effect size 0.72 Standardized mean difference
Adverse events 2.1% Adverse event incidence

Summary

A comprehensive review of 28 domestic and international studies on Korean medicine treatment (herbal medicine, acupuncture, moxibustion, qigong) for Tourette syndrome in children and adolescents. Effect sizes and safety were compared by treatment modality.

Key Conclusion

Combination of herbal medicine (Cheonmagudeung-eum, modified Eokgan-san) and acupuncture treatment was most effective in alleviating Tourette syndrome symptoms, with fewer side effects than Western medication, making it suitable for long-term treatment.

Systematic Review Pediatric / Adolescent Care

Effect of Sihogayonggolmoryeo-tang for Pediatric Anxiety Disorder: A Systematic Review

Yang DS, Im SH, et al.

대한한방신경정신과학회지 (2024)

41.3% SCARED reduction rate
9 studies Included studies
p<0.005 Statistical significance

Sihogayonggolmoryeo-tang reduced SCARED scores by an average of 41.3% in pediatric anxiety disorder, with particularly effective results in anxiety with comorbid sleep disturbance.

Systematic Review Pediatric / Adolescent Care

Effect of Sihogayonggolmoryeo-tang for Pediatric Anxiety Disorder: A Systematic Review

Yang DS, Im SH, et al. 대한한방신경정신과학회지 (2024)
41.3% SCARED reduction rate
9 studies Included studies
p<0.005 Statistical significance

Summary

A systematic review of Sihogayonggolmoryeo-tang treatment efficacy in pediatric anxiety disorder patients. Nine studies were analyzed with SCARED and STAI-C score changes as primary outcome variables.

Key Conclusion

Sihogayonggolmoryeo-tang reduced SCARED scores by an average of 41.3% in pediatric anxiety disorder, with particularly effective results in anxiety with comorbid sleep disturbance.

Meta-Analysis Pediatric / Adolescent Care

Meta-Analysis of Korean Medicine Treatment Effects for Children with School Refusal: Psychological and Physical Symptom Improvement

Hwang JK, Lee EJ, et al.

대한한방소아과학회지 (2023)

8.4 days/month School attendance increase
76.3% Physical symptom improvement rate
312 patients Analysis population

After Korean medicine treatment, school attendance days increased by an average of 8.4 days per month, and 76.3% of accompanying physical symptoms improved, confirming the utility of Korean medicine treatment in the multidimensional approach to school refusal.

Meta-Analysis Pediatric / Adolescent Care

Meta-Analysis of Korean Medicine Treatment Effects for Children with School Refusal: Psychological and Physical Symptom Improvement

Hwang JK, Lee EJ, et al. 대한한방소아과학회지 (2023)
8.4 days/month School attendance increase
76.3% Physical symptom improvement rate
312 patients Analysis population

Summary

Data from 312 children with school refusal were meta-analyzed. Effects of herbal medicine (modified Sosiho-tang, Banhahubak-tang) and acupuncture treatment on school attendance days and accompanying physical symptoms (headache, abdominal pain, nausea) improvement were analyzed.

Key Conclusion

After Korean medicine treatment, school attendance days increased by an average of 8.4 days per month, and 76.3% of accompanying physical symptoms improved, confirming the utility of Korean medicine treatment in the multidimensional approach to school refusal.

RCT Pediatric / Adolescent Care

Randomized Controlled Trial of Modified Gammaekdaejo-tang and Pediatric Acupuncture for Children with Separation Anxiety

Ahn TW, Chung HJ, et al.

대한한방신경정신과학회지 (2024)

SAAS -36.8% Separation anxiety score reduction
74 patients Study population
8 weeks Treatment duration

Combined modified Gammaekdaejo-tang and pediatric acupuncture significantly reduced SAAS scores in children with separation anxiety compared to counseling alone, with concurrent improvement in parent-reported sleep quality.

RCT Pediatric / Adolescent Care

Randomized Controlled Trial of Modified Gammaekdaejo-tang and Pediatric Acupuncture for Children with Separation Anxiety

Ahn TW, Chung HJ, et al. 대한한방신경정신과학회지 (2024)
SAAS -36.8% Separation anxiety score reduction
74 patients Study population
8 weeks Treatment duration

Summary

An RCT comparing a modified Gammaekdaejo-tang and pediatric acupuncture (HT7, PC6) combination group with a counseling alone group in 74 children with separation anxiety disorder. SAAS score changes were evaluated over 8 weeks.

Key Conclusion

Combined modified Gammaekdaejo-tang and pediatric acupuncture significantly reduced SAAS scores in children with separation anxiety compared to counseling alone, with concurrent improvement in parent-reported sleep quality.

Cohort Study Pediatric / Adolescent Care

Cohort Study on Herbal Medicine Treatment Efficacy for Girls with Precocious Puberty: Focus on Modified Jibaekjihwang-tang

Ko SY, Min JH, et al.

대한한방소아과학회지 (2023)

0.7 years Bone age progression slowing
198 patients Study population
12 months Follow-up period

The modified Jibaekjihwang-tang treatment group showed bone age progression slowed by 0.7 years annually, with significant effects also on LH/FSH ratio stabilization, presenting the potential of herbal medicine treatment for precocious puberty management.

Cohort Study Pediatric / Adolescent Care

Cohort Study on Herbal Medicine Treatment Efficacy for Girls with Precocious Puberty: Focus on Modified Jibaekjihwang-tang

Ko SY, Min JH, et al. 대한한방소아과학회지 (2023)
0.7 years Bone age progression slowing
198 patients Study population
12 months Follow-up period

Summary

A cohort study following 198 girls diagnosed with precocious puberty for 12 months. Bone age progression rate, breast development stage (Tanner stage), and sex hormone levels were compared between modified Jibaekjihwang-tang treatment and non-treatment groups.

Key Conclusion

The modified Jibaekjihwang-tang treatment group showed bone age progression slowed by 0.7 years annually, with significant effects also on LH/FSH ratio stabilization, presenting the potential of herbal medicine treatment for precocious puberty management.

Systematic Review Pediatric / Adolescent Care

Effect of Combined Herbal Medicine and Growth Acupuncture on Height Velocity in Children with Growth Disorders: A Systematic Review

Kim SH, Lee JY, et al.

대한한방소아과학회지 (2024)

2.1 cm Annual growth velocity increase
87.3% Treatment response rate
p<0.01 Statistical significance

Combined herbal medicine and growth acupuncture treatment increases annual growth velocity by an average of 2.1 cm in children with growth disorders, with superior effects particularly in bone age delay type.

Systematic Review Pediatric / Adolescent Care

Effect of Combined Herbal Medicine and Growth Acupuncture on Height Velocity in Children with Growth Disorders: A Systematic Review

Kim SH, Lee JY, et al. 대한한방소아과학회지 (2024)
2.1 cm Annual growth velocity increase
87.3% Treatment response rate
p<0.01 Statistical significance

Summary

A systematic review analyzing the effects of combined herbal medicine (modified Nokyongdaebo-tang) and growth acupuncture in 412 children with growth disorders. The group treated for 6 months or longer showed significantly increased annual growth velocity.

Key Conclusion

Combined herbal medicine and growth acupuncture treatment increases annual growth velocity by an average of 2.1 cm in children with growth disorders, with superior effects particularly in bone age delay type.

Meta-Analysis Pediatric / Adolescent Care

Meta-Analysis of Kidney-Tonifying and Qi-Replenishing Herbal Medicine Treatment for Children with Short Stature

Park JH, Choi MK, et al.

한방재활의학과학회지 (2023)

3.8 cm/6 months Mean height increase
IGF-1 +23.4% Growth factor elevation
8 studies Included studies

Kidney-tonifying and qi-replenishing herbal medicine significantly elevates IGF-1 levels in children with short stature and shows an average height increase of 3.8 cm over 6 months, demonstrating superior effects compared to controls.

Meta-Analysis Pediatric / Adolescent Care

Meta-Analysis of Kidney-Tonifying and Qi-Replenishing Herbal Medicine Treatment for Children with Short Stature

Park JH, Choi MK, et al. 한방재활의학과학회지 (2023)
3.8 cm/6 months Mean height increase
IGF-1 +23.4% Growth factor elevation
8 studies Included studies

Summary

A meta-analysis evaluating the growth-promoting effects of kidney-tonifying and qi-replenishing herbal medicine treatment using data from 580 children diagnosed with short stature. IGF-1 level changes and height increase were set as primary outcome variables.

Key Conclusion

Kidney-tonifying and qi-replenishing herbal medicine significantly elevates IGF-1 levels in children with short stature and shows an average height increase of 3.8 cm over 6 months, demonstrating superior effects compared to controls.

RCT Pediatric / Adolescent Care

Randomized Controlled Trial of Combined Chuna Therapy and Herbal Medicine for Growth Plate Management

Lee HJ, Kim DW, et al.

대한추나의학회지 (2024)

4.2 months Growth plate activity extension
92.7% Spinal alignment improvement rate
n=96 Study population

Combined Chuna therapy and herbal medicine treatment prolonged growth plate activity duration by an average of 4.2 months compared to herbal medicine alone, with concurrent scoliosis correction effects.

RCT Pediatric / Adolescent Care

Randomized Controlled Trial of Combined Chuna Therapy and Herbal Medicine for Growth Plate Management

Lee HJ, Kim DW, et al. 대한추나의학회지 (2024)
4.2 months Growth plate activity extension
92.7% Spinal alignment improvement rate
n=96 Study population

Summary

An RCT comparing a Chuna therapy and herbal medicine combination group with an herbal medicine alone group in 96 adolescents before growth plate closure. Spinal alignment correction and growth plate activity were evaluated over 12 weeks.

Key Conclusion

Combined Chuna therapy and herbal medicine treatment prolonged growth plate activity duration by an average of 4.2 months compared to herbal medicine alone, with concurrent scoliosis correction effects.

Cohort Study Pediatric / Adolescent Care

Long-Term Follow-Up Cohort Study of Korean Medicine Combination Therapy for Childhood Obesity

Choi YS, Jung EH, et al.

대한한방소아과학회지 (2023)

BMI -2.3 BMI reduction
78.2% Weight loss maintenance rate
24 months Follow-up period

Children with obesity receiving Korean medicine combination therapy showed an average BMI reduction of 2.3 kg/m2 after 24 months, with superior appetite control effects in the auricular acupuncture combination group.

Cohort Study Pediatric / Adolescent Care

Long-Term Follow-Up Cohort Study of Korean Medicine Combination Therapy for Childhood Obesity

Choi YS, Jung EH, et al. 대한한방소아과학회지 (2023)
BMI -2.3 BMI reduction
78.2% Weight loss maintenance rate
24 months Follow-up period

Summary

A cohort study following 234 children with obesity for 24 months. Weight loss and metabolic indicator changes from combination therapy including herbal medicine (modified Bangpungtongseong-san), auricular acupuncture, and dietary guidance were analyzed.

Key Conclusion

Children with obesity receiving Korean medicine combination therapy showed an average BMI reduction of 2.3 kg/m2 after 24 months, with superior appetite control effects in the auricular acupuncture combination group.

Cross-Sectional Pediatric / Adolescent Care

Cross-Sectional Survey Study on Herbal Medicine Treatment Efficacy for Pediatric Atopic Dermatitis

Yoon SK, Han JW, et al.

대한한방안이비인후피부과학회지 (2024)

42.1% SCORAD reduction rate
387 patients Study population
63.8% Steroid reduction success rate

Herbal medicine treatment centered on modified Sopung-san reduced SCORAD index by an average of 42.1% and significantly decreased steroid use frequency.

Cross-Sectional Pediatric / Adolescent Care

Cross-Sectional Survey Study on Herbal Medicine Treatment Efficacy for Pediatric Atopic Dermatitis

Yoon SK, Han JW, et al. 대한한방안이비인후피부과학회지 (2024)
42.1% SCORAD reduction rate
387 patients Study population
63.8% Steroid reduction success rate

Summary

A cross-sectional analysis of medical records from 387 pediatric patients with atopic dermatitis who visited Korean medicine clinics. SCORAD index changes and herbal medicine prescription patterns were investigated.

Key Conclusion

Herbal medicine treatment centered on modified Sopung-san reduced SCORAD index by an average of 42.1% and significantly decreased steroid use frequency.

Before-After Pediatric / Adolescent Care

Pre-Post Study of Skin Barrier Function Changes in Infants with Atopic Eczema After Korean Medicine Treatment

Kim MJ, Park SY, et al.

대한한방소아과학회지 (2023)

35.7% TEWL reduction rate
28.4% Skin hydration increase
8 weeks Treatment duration

After 8 weeks of combined herbal bathing therapy and oral medication, TEWL decreased by 35.7% and skin hydration increased by 28.4%, demonstrating significant improvement in skin barrier function.

Before-After Pediatric / Adolescent Care

Pre-Post Study of Skin Barrier Function Changes in Infants with Atopic Eczema After Korean Medicine Treatment

Kim MJ, Park SY, et al. 대한한방소아과학회지 (2023)
35.7% TEWL reduction rate
28.4% Skin hydration increase
8 weeks Treatment duration

Summary

A pre-post comparison study measuring transepidermal water loss (TEWL) and skin hydration changes before and after herbal bathing therapy and oral medication in 45 infants with infantile eczema.

Key Conclusion

After 8 weeks of combined herbal bathing therapy and oral medication, TEWL decreased by 35.7% and skin hydration increased by 28.4%, demonstrating significant improvement in skin barrier function.