금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
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Total 91 papers

Before-After Pediatric / Adolescent Care

Pre-Post Comparison Study of Immune Indicator Changes After Herbal Medicine Treatment in Children with Recurrent Upper Respiratory Tract Infections

Jang HY, Kim WS, et al.

대한한방내과학회지 (2023)

NK +26.3% NK cell activity elevation
CD4/CD8 normalized T-cell ratio improvement
67 patients Study population

After modified Bojungikgi-tang treatment, CD4+/CD8+ ratio normalized and NK cell activity and IFN-g levels significantly increased, confirming cellular immune-enhancing effects.

Before-After Pediatric / Adolescent Care

Pre-Post Comparison Study of Immune Indicator Changes After Herbal Medicine Treatment in Children with Recurrent Upper Respiratory Tract Infections

Jang HY, Kim WS, et al. 대한한방내과학회지 (2023)
NK +26.3% NK cell activity elevation
CD4/CD8 normalized T-cell ratio improvement
67 patients Study population

Summary

A pre-post comparison over 12 weeks of T-cell subsets (CD4+, CD8+), NK cells, and cytokines (IL-2, IFN-g) before and after modified Bojungikgi-tang administration in 67 children with recurrent upper respiratory tract infections.

Key Conclusion

After modified Bojungikgi-tang treatment, CD4+/CD8+ ratio normalized and NK cell activity and IFN-g levels significantly increased, confirming cellular immune-enhancing effects.

Case Study Pediatric / Adolescent Care

Case Report of 6 Cases of Combined Chuna Therapy and Herbal Medicine for Pediatric Headache

Gong JH, Im SK, et al.

대한추나의학회지 (2024)

Headache -69.9% Headache frequency reduction
6 cases Number of cases
8 weeks Treatment duration

After combined Chuna therapy and herbal medicine treatment, headache frequency decreased from an average of 12.3 to 3.7 times per month, and cervical range of motion also significantly improved, confirming the efficacy of cervical Chuna for pediatric headache.

Case Study Pediatric / Adolescent Care

Case Report of 6 Cases of Combined Chuna Therapy and Herbal Medicine for Pediatric Headache

Gong JH, Im SK, et al. 대한추나의학회지 (2024)
Headache -69.9% Headache frequency reduction
6 cases Number of cases
8 weeks Treatment duration

Summary

A case report on 6 children with chronic headache (tension-type) treated with combined cervical Chuna therapy and modified Cheonung-dajosan. Headache frequency, VAS, and headache diary were analyzed over 8 weeks.

Key Conclusion

After combined Chuna therapy and herbal medicine treatment, headache frequency decreased from an average of 12.3 to 3.7 times per month, and cervical range of motion also significantly improved, confirming the efficacy of cervical Chuna for pediatric headache.

Meta-Analysis Pediatric / Adolescent Care

Meta-Analysis of Gyeongokgo Administration for Pediatric Immunity Enhancement

Kwon BH, Song YJ, et al.

대한한방소아과학회지 (2023)

IgA +18.7% Immunoglobulin elevation
Infection -2.9/year Infection frequency reduction
478 patients Analysis population

Gyeongokgo administration elevated IgA levels by an average of 18.7% in children and reduced annual respiratory infection frequency by 2.9 episodes, showing significant effects on immunity enhancement.

Meta-Analysis Pediatric / Adolescent Care

Meta-Analysis of Gyeongokgo Administration for Pediatric Immunity Enhancement

Kwon BH, Song YJ, et al. 대한한방소아과학회지 (2023)
IgA +18.7% Immunoglobulin elevation
Infection -2.9/year Infection frequency reduction
478 patients Analysis population

Summary

A meta-analysis of data from 478 pediatric patients with immune deficiency, evaluating immune indicator (IgG, IgA, NK cell) and infection frequency changes from Gyeongokgo administration.

Key Conclusion

Gyeongokgo administration elevated IgA levels by an average of 18.7% in children and reduced annual respiratory infection frequency by 2.9 episodes, showing significant effects on immunity enhancement.

Narrative Review Pediatric / Adolescent Care

Recent Trends in Auricular Acupuncture Treatment for Pediatric Sleep Disorders: A Narrative Review

Han MJ, Choi GS, et al.

대한한방신경정신과학회지 (2023)

19 studies Reviewed studies
Sleep latency -19.2 min Sleep latency reduction
Adverse events 0.5% Adverse event incidence

Auricular acupuncture is effective for sleep latency reduction and sleep efficiency improvement in pediatric sleep disorders, and being non-invasive with almost no side effects, was confirmed as a suitable treatment for pediatric patients.

Narrative Review Pediatric / Adolescent Care

Recent Trends in Auricular Acupuncture Treatment for Pediatric Sleep Disorders: A Narrative Review

Han MJ, Choi GS, et al. 대한한방신경정신과학회지 (2023)
19 studies Reviewed studies
Sleep latency -19.2 min Sleep latency reduction
Adverse events 0.5% Adverse event incidence

Summary

A comprehensive review of 19 domestic and international studies on auricular acupuncture (Shenmen, Heart, Brain, Sympathetic point) for pediatric sleep disorders. Mechanism of action, application methods, and safety of auricular acupuncture were analyzed.

Key Conclusion

Auricular acupuncture is effective for sleep latency reduction and sleep efficiency improvement in pediatric sleep disorders, and being non-invasive with almost no side effects, was confirmed as a suitable treatment for pediatric patients.

Systematic Review Pediatric / Adolescent Care

Constitutional Improvement Effect of Hwanggigeonjung-tang for Frail Children: A Systematic Review

Na SH, Bak JY, et al.

대한한방소아과학회지 (2024)

1.4 kg/3 months Weight increase
Infection -42.7% Infection frequency reduction
12 studies Included studies

Hwanggigeonjung-tang increased weight by an average of 1.4 kg over 3 months and reduced infection frequency by 42.7% in frail children, showing significant effects on overall constitutional improvement.

Systematic Review Pediatric / Adolescent Care

Constitutional Improvement Effect of Hwanggigeonjung-tang for Frail Children: A Systematic Review

Na SH, Bak JY, et al. 대한한방소아과학회지 (2024)
1.4 kg/3 months Weight increase
Infection -42.7% Infection frequency reduction
12 studies Included studies

Summary

A systematic review of constitutional improvement effects of Hwanggigeonjung-tang in frail children. Twelve studies were analyzed for weight gain, appetite recovery, infection frequency reduction, and physical strength improvement.

Key Conclusion

Hwanggigeonjung-tang increased weight by an average of 1.4 kg over 3 months and reduced infection frequency by 42.7% in frail children, showing significant effects on overall constitutional improvement.

Meta-Analysis Pediatric / Adolescent Care

Meta-Analysis of Korean Medicine Combination Therapy for Adolescent Academic Stress and Physical Symptoms

Yim KH, Sohn TW, et al.

대한한방신경정신과학회지 (2023)

PSS -37.2% Stress score reduction
81.5% Physical symptom improvement rate
527 patients Analysis population

Korean medicine combination therapy reduced adolescent PSS scores by an average of 37.2% and improved 81.5% of accompanying physical symptoms, proving effective for mind-body integrated treatment of academic stress.

Meta-Analysis Pediatric / Adolescent Care

Meta-Analysis of Korean Medicine Combination Therapy for Adolescent Academic Stress and Physical Symptoms

Yim KH, Sohn TW, et al. 대한한방신경정신과학회지 (2023)
PSS -37.2% Stress score reduction
81.5% Physical symptom improvement rate
527 patients Analysis population

Summary

A meta-analysis of data from 527 adolescents complaining of physical symptoms (headache, abdominal pain, insomnia, fatigue) due to academic stress. Effects of combined herbal medicine, acupuncture, and auricular acupuncture treatment on stress indicators and physical symptoms were analyzed.

Key Conclusion

Korean medicine combination therapy reduced adolescent PSS scores by an average of 37.2% and improved 81.5% of accompanying physical symptoms, proving effective for mind-body integrated treatment of academic stress.

Narrative Review Pediatric / Adolescent Care

Narrative Review of Korean Medicine Weight Management Program Effects in Children with Obesity

Ha JW, Nam SB, et al.

대한한방소아과학회지 (2023)

22 studies Reviewed studies
68.3% 12-month weight maintenance rate
BMI -1.9 Mean BMI reduction

Korean medicine combination weight management programs were effective in BMI reduction and body fat reduction for childhood obesity, with particularly high 12-month maintenance rate of 68.3% when auricular acupuncture and dietary guidance were combined.

Narrative Review Pediatric / Adolescent Care

Narrative Review of Korean Medicine Weight Management Program Effects in Children with Obesity

Ha JW, Nam SB, et al. 대한한방소아과학회지 (2023)
22 studies Reviewed studies
68.3% 12-month weight maintenance rate
BMI -1.9 Mean BMI reduction

Summary

A comprehensive review of 22 domestic and international studies on Korean medicine weight management programs for childhood obesity (herbal medicine, auricular acupuncture, dietary therapy, exercise guidance). Effects by program component and long-term maintenance rates were analyzed.

Key Conclusion

Korean medicine combination weight management programs were effective in BMI reduction and body fat reduction for childhood obesity, with particularly high 12-month maintenance rate of 68.3% when auricular acupuncture and dietary guidance were combined.

Meta-Analysis Pediatric / Adolescent Care

Meta-Analysis of Acupuncture for Nasal Function Improvement in Pediatric Rhinitis: Focus on LI20 and LI4

Kim AS, Park BJ, et al.

대한침구의학회지 (2023)

31.4% Nasal airway patency improvement
55.7% Sneeze reduction rate
623 patients Analysis population

LI20 and LI4 acupuncture treatment improved nasal airway patency by 31.4% and reduced sneeze frequency by 55.7% in pediatric rhinitis patients, showing significant effects on nasal function improvement.

Meta-Analysis Pediatric / Adolescent Care

Meta-Analysis of Acupuncture for Nasal Function Improvement in Pediatric Rhinitis: Focus on LI20 and LI4

Kim AS, Park BJ, et al. 대한침구의학회지 (2023)
31.4% Nasal airway patency improvement
55.7% Sneeze reduction rate
623 patients Analysis population

Summary

Acupuncture treatment data from 623 pediatric patients with allergic rhinitis were meta-analyzed. Changes in nasal airway resistance, sneeze frequency, and nasal congestion VAS from LI20 and LI4-focused acupuncture were analyzed.

Key Conclusion

LI20 and LI4 acupuncture treatment improved nasal airway patency by 31.4% and reduced sneeze frequency by 55.7% in pediatric rhinitis patients, showing significant effects on nasal function improvement.

RCT Pediatric / Adolescent Care

Randomized Controlled Trial of Abdominal Chuna Therapy for Pediatric Constipation

Oh YH, Jang MK, et al.

대한추나의학회지 (2024)

+1.8/week Additional bowel frequency increase
68 patients Study population
4 weeks Treatment duration

The abdominal Chuna therapy combination group showed an additional 1.8 episodes per week increase in bowel frequency compared to the herbal medicine alone group, with significant differences also in defecation pain reduction, confirming additional effects of abdominal Chuna.

RCT Pediatric / Adolescent Care

Randomized Controlled Trial of Abdominal Chuna Therapy for Pediatric Constipation

Oh YH, Jang MK, et al. 대한추나의학회지 (2024)
+1.8/week Additional bowel frequency increase
68 patients Study population
4 weeks Treatment duration

Summary

An RCT comparing an abdominal Chuna therapy plus herbal medicine combination group with an herbal medicine alone group in 68 children with functional constipation. Bowel frequency, stool form, residual stool sensation, and pain during defecation were evaluated over 4 weeks.

Key Conclusion

The abdominal Chuna therapy combination group showed an additional 1.8 episodes per week increase in bowel frequency compared to the herbal medicine alone group, with significant differences also in defecation pain reduction, confirming additional effects of abdominal Chuna.

Cross-Sectional Pediatric / Adolescent Care

Cross-Sectional Analysis of Scalp Acupuncture Treatment for Children with Tic Disorder

Jin SH, Lee JM, et al.

대한침구의학회지 (2024)

78.4% Symptom improvement rate
97 patients Analysis population
Motor tic 84.2% Motor tic improvement rate

Of children with tic disorder who received scalp acupuncture treatment, 78.4% showed reduced tic frequency, with particularly higher response rates for motor tics, confirming the potential of scalp acupuncture for tic disorder treatment.

Cross-Sectional Pediatric / Adolescent Care

Cross-Sectional Analysis of Scalp Acupuncture Treatment for Children with Tic Disorder

Jin SH, Lee JM, et al. 대한침구의학회지 (2024)
78.4% Symptom improvement rate
97 patients Analysis population
Motor tic 84.2% Motor tic improvement rate

Summary

A cross-sectional analysis of medical records from 97 pediatric patients with tic disorder who visited Korean medicine clinics. Tic frequency and intensity changes after scalp acupuncture (chorea-tremor area, emotional area) treatment were investigated.

Key Conclusion

Of children with tic disorder who received scalp acupuncture treatment, 78.4% showed reduced tic frequency, with particularly higher response rates for motor tics, confirming the potential of scalp acupuncture for tic disorder treatment.

Before-After Pediatric / Adolescent Care

Pre-Post Comparison Study of Laser Acupuncture Treatment for Children with Enuresis

Chung WK, Park EH, et al.

대한한방소아과학회지 (2023)

60.4% Enuresis frequency reduction rate
Compliance 92.3% Treatment compliance
52 patients Study population

After 8 weeks of laser acupuncture treatment, enuresis frequency decreased from 4.8 to 1.9 episodes per week, and treatment compliance was very high at 92.3% as a non-invasive treatment for pediatric patients.

Before-After Pediatric / Adolescent Care

Pre-Post Comparison Study of Laser Acupuncture Treatment for Children with Enuresis

Chung WK, Park EH, et al. 대한한방소아과학회지 (2023)
60.4% Enuresis frequency reduction rate
Compliance 92.3% Treatment compliance
52 patients Study population

Summary

A pre-post comparison study performing laser acupuncture at CV4, CV3, and SP6 in 52 children with enuresis. Enuresis frequency, maximum bladder capacity, and nocturnal urine volume were measured over 8 weeks.

Key Conclusion

After 8 weeks of laser acupuncture treatment, enuresis frequency decreased from 4.8 to 1.9 episodes per week, and treatment compliance was very high at 92.3% as a non-invasive treatment for pediatric patients.

Narrative Review Pediatric / Adolescent Care

Recent Literature Review on Korean Medicine Treatment for Pediatric Anxiety and Sleep Disorders

Yang WS, Kim DH, et al.

대한한방신경정신과학회지 (2023)

37 studies Reviewed studies
15 years Search period
Adverse events 1.8% Adverse event incidence

Combinations of Sihogayonggolmoryeo-tang, Sanjoin-tang series herbal medicines, and auricular acupuncture were most effective for pediatric anxiety-sleep disorder comorbid symptoms, with markedly fewer side effects compared to benzodiazepine medications.

Narrative Review Pediatric / Adolescent Care

Recent Literature Review on Korean Medicine Treatment for Pediatric Anxiety and Sleep Disorders

Yang WS, Kim DH, et al. 대한한방신경정신과학회지 (2023)
37 studies Reviewed studies
15 years Search period
Adverse events 1.8% Adverse event incidence

Summary

A comprehensive review of 37 studies from the past 15 years on Korean medicine treatment for pediatric anxiety and sleep disorders. Effects of various Korean medicine interventions including herbal medicine, acupuncture, auricular acupuncture, and aromatherapy were compared and analyzed.

Key Conclusion

Combinations of Sihogayonggolmoryeo-tang, Sanjoin-tang series herbal medicines, and auricular acupuncture were most effective for pediatric anxiety-sleep disorder comorbid symptoms, with markedly fewer side effects compared to benzodiazepine medications.