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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 68 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Before-After Mental Health

Effect of Korean Medicine Sleep Yangsaeng Method on Sleep Quality in Insomnia Patients: A Pre-Post Comparison Study

Moon SJ, Kim CH, Woo HS, et al.

Sleep Medicine (2024)

6.4 points PSQI reduction
89% Sleep efficiency improvement
75 patients Participants

Korean medicine sleep yangsaeng methods significantly improve sleep quality and can manage insomnia without sleep medication dependence.

View Source 2024
Before-After Mental Health

Effect of Korean Medicine Sleep Yangsaeng Method on Sleep Quality in Insomnia Patients: A Pre-Post Comparison Study

Moon SJ, Kim CH, Woo HS, et al. Sleep Medicine (2024)
6.4 points PSQI reduction
89% Sleep efficiency improvement
75 patients Participants

Summary

Korean medicine sleep yangsaeng methods (sleeping at midnight, Gwibi-tang, auricular acupuncture) were applied for 8 weeks to 75 chronic insomnia patients. PSQI total score decreased by an average of 6.4 points, with sleep efficiency improving from 78% to 89%.

Key Conclusion

Korean medicine sleep yangsaeng methods significantly improve sleep quality and can manage insomnia without sleep medication dependence.

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Case Study Mental Health

Korean Medicine Treatment Case Report for Adrenal Fatigue Due to Chronic Stress

Go YS, Lee MH, et al.

Case Reports in Medicine (2021)

4 cases Number of Cases
75% Fatigue Improvement Rate
12 weeks Treatment Period

Korean medicine treatment can contribute to fatigue symptom and adrenal function recovery in adrenal fatigue syndrome patients.

View Source 2021
Case Study Mental Health

Korean Medicine Treatment Case Report for Adrenal Fatigue Due to Chronic Stress

Go YS, Lee MH, et al. Case Reports in Medicine (2021)
4 cases Number of Cases
75% Fatigue Improvement Rate
12 weeks Treatment Period

Summary

Cases of modified Bojungikgi-tang and acupuncture treatment for 12 weeks in 4 patients with adrenal fatigue syndrome due to chronic stress. Fatigue severity and morning cortisol improved in all patients.

Key Conclusion

Korean medicine treatment can contribute to fatigue symptom and adrenal function recovery in adrenal fatigue syndrome patients.

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RCT Mental Health

Effect of Combined Herbal Medicine-Cognitive Behavioral Therapy for Social Anxiety Disorder Patients: An Exploratory RCT

Kim SY, Lim HJ, et al.

Social Psychiatry and Psychiatric Epidemiology (2023)

50 subjects Participants
42% LSAS Improvement Rate
12 weeks Treatment Period

Combined herbal medicine-cognitive behavioral therapy shows superior effects to CBT alone in social anxiety disorder.

View Source 2023
RCT Mental Health

Effect of Combined Herbal Medicine-Cognitive Behavioral Therapy for Social Anxiety Disorder Patients: An Exploratory RCT

Kim SY, Lim HJ, et al. Social Psychiatry and Psychiatric Epidemiology (2023)
50 subjects Participants
42% LSAS Improvement Rate
12 weeks Treatment Period

Summary

Fifty patients with social anxiety disorder were randomly assigned to herbal medicine + CBT and CBT alone groups and compared for 12 weeks. LSAS scores and avoidance behavior indicators decreased significantly more in the combined group.

Key Conclusion

Combined herbal medicine-cognitive behavioral therapy shows superior effects to CBT alone in social anxiety disorder.

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RCT Mental Health

Effect of Mindfulness-Based Korean Medicine Treatment (MBKM) on Generalized Anxiety Disorder: An Exploratory RCT

Suh YJ, Kim EH, et al.

Journal of Anxiety Disorders (2024)

60 subjects Participants
49% GAD-7 Improvement Rate
10 weeks Program Period

Mindfulness-based Korean medicine treatment is a promising integrated treatment program for relieving generalized anxiety disorder symptoms.

View Source 2024
RCT Mental Health

Effect of Mindfulness-Based Korean Medicine Treatment (MBKM) on Generalized Anxiety Disorder: An Exploratory RCT

Suh YJ, Kim EH, et al. Journal of Anxiety Disorders (2024)
60 subjects Participants
49% GAD-7 Improvement Rate
10 weeks Program Period

Summary

Sixty patients with generalized anxiety disorder were randomly assigned to a mindfulness-based Korean medicine treatment group and a waiting list group and compared for 10 weeks. GAD-7 and PSWQ scores decreased significantly in the Korean medicine treatment group.

Key Conclusion

Mindfulness-based Korean medicine treatment is a promising integrated treatment program for relieving generalized anxiety disorder symptoms.

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Cross-Sectional Mental Health

Validation of Clinical Relevance of Korean Medicine Heart-Gallbladder Deficiency Pattern in Panic Disorder

Kang JW, Park SJ, et al.

Journal of Korean Medicine (2020)

180 subjects Analysis Subjects
r=0.74 Correlation Coefficient
p<0.001 Statistical Significance

Heart-gallbladder deficiency pattern is a pattern type with clinical validity for Korean medicine evaluation of panic disorder.

View Source 2020
Cross-Sectional Mental Health

Validation of Clinical Relevance of Korean Medicine Heart-Gallbladder Deficiency Pattern in Panic Disorder

Kang JW, Park SJ, et al. Journal of Korean Medicine (2020)
180 subjects Analysis Subjects
r=0.74 Correlation Coefficient
p<0.001 Statistical Significance

Summary

A cross-sectional study comparing heart-gallbladder deficiency pattern questionnaire scores in 120 panic disorder patients and 60 healthy controls and analyzing correlation with PDSS scores. Heart-gallbladder deficiency scores showed high correlation with panic symptom severity.

Key Conclusion

Heart-gallbladder deficiency pattern is a pattern type with clinical validity for Korean medicine evaluation of panic disorder.

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Cohort Study Mental Health

3-Year Follow-Up Study on Recurrence Rate of Depression Patients Receiving Korean Medicine Treatment

Chung HK, Lee WS, Pham TN, et al.

Journal of Affective Disorders (2023)

200 subjects Participants
28% 3-year Recurrence Rate
OR 0.42 Maintenance Treatment Protective Effect

Continued maintenance treatment after Korean medicine treatment can significantly lower depression recurrence risk.

View Source 2023
Cohort Study Mental Health

3-Year Follow-Up Study on Recurrence Rate of Depression Patients Receiving Korean Medicine Treatment

Chung HK, Lee WS, Pham TN, et al. Journal of Affective Disorders (2023)
200 subjects Participants
28% 3-year Recurrence Rate
OR 0.42 Maintenance Treatment Protective Effect

Summary

Two hundred depression patients in remission after Korean medicine treatment were followed for 3 years to analyze recurrence rates and related factors. The 3-year recurrence rate was 28%, and maintenance treatment continuation was a major predictive factor.

Key Conclusion

Continued maintenance treatment after Korean medicine treatment can significantly lower depression recurrence risk.

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Systematic Review Mental Health

Effect of Pharmacopuncture Treatment for Autonomic Dysfunction: A Systematic Review

Noh JH, Kim WS, Chen Z, et al.

Journal of Pharmacopuncture (2022)

14 studies Included Studies
11 studies Positive Results
Moderate Evidence Level

Pharmacopuncture treatment is a promising Korean medicine intervention for autonomic dysfunction management.

View Source 2022
Systematic Review Mental Health

Effect of Pharmacopuncture Treatment for Autonomic Dysfunction: A Systematic Review

Noh JH, Kim WS, Chen Z, et al. Journal of Pharmacopuncture (2022)
14 studies Included Studies
11 studies Positive Results
Moderate Evidence Level

Summary

Fourteen studies evaluating the effect of pharmacopuncture treatment for autonomic dysfunction were systematically reviewed. Pharmacopuncture treatment showed positive results in HRV and autonomic symptom score improvement.

Key Conclusion

Pharmacopuncture treatment is a promising Korean medicine intervention for autonomic dysfunction management.

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Before-After Mental Health

Impact of Combined Meditation and Acupuncture Treatment on EEG in Chronic Anxiety Patients

Lee BH, Song MR, et al.

Mindfulness (2023)

50 subjects Participants
Alpha wave 28% increase Brain Wave Change
8 weeks Program Period

Combined meditation-acupuncture treatment is effective for stabilizing brain waves in anxiety patients.

View Source 2023
Before-After Mental Health

Impact of Combined Meditation and Acupuncture Treatment on EEG in Chronic Anxiety Patients

Lee BH, Song MR, et al. Mindfulness (2023)
50 subjects Participants
Alpha wave 28% increase Brain Wave Change
8 weeks Program Period

Summary

A meditation-acupuncture combined program was administered for 8 weeks to 50 chronic anxiety patients, and electroencephalogram (EEG) changes were analyzed. Alpha wave increase and beta wave decrease were significantly observed.

Key Conclusion

Combined meditation-acupuncture treatment is effective for stabilizing brain waves in anxiety patients.

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Case Study Mental Health

Korean Medicine Approach to Psychosomatic Disorders: A Case Series and Literature Review

Moon TK, Choi EY, et al.

Integrative Medicine Research (2021)

10 cases Number of Cases
80% Improvement Rate
5 types Psychosomatic Disorder Types

Korean medicine mind-body integrated treatment can simultaneously improve physical and psychological symptoms in psychosomatic disorder patients.

View Source 2021
Case Study Mental Health

Korean Medicine Approach to Psychosomatic Disorders: A Case Series and Literature Review

Moon TK, Choi EY, et al. Integrative Medicine Research (2021)
10 cases Number of Cases
80% Improvement Rate
5 types Psychosomatic Disorder Types

Summary

Cases of pattern-specific Korean medicine treatment in 10 patients with various psychosomatic disorders (irritable bowel syndrome, tension headache, chronic fatigue) were reported, and related literature was reviewed.

Key Conclusion

Korean medicine mind-body integrated treatment can simultaneously improve physical and psychological symptoms in psychosomatic disorder patients.

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Cohort Study Mental Health

Effect of Korean Medicine Combined Treatment in Anxiety-Depression Patients After COVID-19: A Cohort Study

Yoo HK, Park GN, et al.

Journal of Korean Medicine (2023)

60 subjects Participants
55% PHQ-9 Improvement Rate
12 weeks Follow-up Period

Korean medicine combined treatment is effective for managing anxiety-depressive symptoms occurring as COVID-19 sequelae.

View Source 2023
Cohort Study Mental Health

Effect of Korean Medicine Combined Treatment in Anxiety-Depression Patients After COVID-19: A Cohort Study

Yoo HK, Park GN, et al. Journal of Korean Medicine (2023)
60 subjects Participants
55% PHQ-9 Improvement Rate
12 weeks Follow-up Period

Summary

A cohort study following 60 patients with anxiety and depressive symptoms after COVID-19 infection for 12 weeks, divided into Korean medicine treatment and general management groups. PHQ-9 and GAD-7 scores improved significantly in the Korean medicine treatment group.

Key Conclusion

Korean medicine combined treatment is effective for managing anxiety-depressive symptoms occurring as COVID-19 sequelae.

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Narrative Review Mental Health

Role of Gut-Brain Axis in Korean Medicine Mental Health Treatment: An Integrated Review

Ahn GJ, Kim HY, Patel R, et al.

Frontiers in Psychiatry (2025)

48 sources Reviewed Literature
3 pathways Main Pathways
Gut microbiota Key Mechanism

Korean medicine treatment can improve mental health symptoms such as depression and anxiety through gut-brain axis regulation.

View Source 2025
Narrative Review Mental Health

Role of Gut-Brain Axis in Korean Medicine Mental Health Treatment: An Integrated Review

Ahn GJ, Kim HY, Patel R, et al. Frontiers in Psychiatry (2025)
48 sources Reviewed Literature
3 pathways Main Pathways
Gut microbiota Key Mechanism

Summary

Basic and clinical studies on the impact of Korean medicine treatment (herbal medicine, acupuncture) on mental health via the gut-brain axis were integratively reviewed. Various pathways including gut microbiota regulation and vagal nerve activation were confirmed.

Key Conclusion

Korean medicine treatment can improve mental health symptoms such as depression and anxiety through gut-brain axis regulation.

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RCT Mental Health

Effect of Herbal Medicine Combination on Withdrawal Symptom Prevention During Antidepressant Tapering: An RCT

Song BK, Lee YH, et al.

Journal of Clinical Psychopharmacology (2024)

70 subjects Participants
28% vs 58% Withdrawal Symptom Incidence
16 weeks Tapering Period

Herbal medicine combination is effective for preventing withdrawal symptoms during antidepressant tapering.

View Source 2024
RCT Mental Health

Effect of Herbal Medicine Combination on Withdrawal Symptom Prevention During Antidepressant Tapering: An RCT

Song BK, Lee YH, et al. Journal of Clinical Psychopharmacology (2024)
70 subjects Participants
28% vs 58% Withdrawal Symptom Incidence
16 weeks Tapering Period

Summary

Seventy depression patients planning antidepressant tapering were randomly assigned to herbal medicine combined and non-combined groups, and withdrawal symptom incidence during the tapering process was compared. Withdrawal symptoms were significantly fewer in the herbal medicine combined group.

Key Conclusion

Herbal medicine combination is effective for preventing withdrawal symptoms during antidepressant tapering.

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