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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 68 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Cohort Study Mental Health

Cohort Study of Herbal Medicine (Guibi-tang) for Geriatric Depression

Moon KW, Go JH, Shin BC, et al.

Aging & Mental Health (2024)

41% GDS Reduction
180 subjects Participants
24 weeks Follow-up Period

Guibi-tang is effective for improving geriatric depression and preventing accompanying cognitive decline.

View Source 2024
Cohort Study Mental Health

Cohort Study of Herbal Medicine (Guibi-tang) for Geriatric Depression

Moon KW, Go JH, Shin BC, et al. Aging & Mental Health (2024)
41% GDS Reduction
180 subjects Participants
24 weeks Follow-up Period

Summary

One hundred eighty elderly depression patients aged 65 and older were followed for 24 weeks, divided into Guibi-tang administration and non-administration groups. GDS scores decreased by 41% and cognitive function (MMSE) was significantly maintained in the Guibi-tang group.

Key Conclusion

Guibi-tang is effective for improving geriatric depression and preventing accompanying cognitive decline.

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RCT Mental Health

Anti-Stress Effect of Herbal Medicine (Soyo-san) in Adjustment Disorder Patients: A Randomized Controlled Trial

Baek IH, Lee JH, Park CW, et al.

Stress and Health (2023)

39% Stress Reduction
90 subjects Participants
Cortisol normalization Physiological Indicator

Soyo-san has effects on regulating the stress response of adjustment disorder at the physiological level.

View Source 2023
RCT Mental Health

Anti-Stress Effect of Herbal Medicine (Soyo-san) in Adjustment Disorder Patients: A Randomized Controlled Trial

Baek IH, Lee JH, Park CW, et al. Stress and Health (2023)
39% Stress Reduction
90 subjects Participants
Cortisol normalization Physiological Indicator

Summary

Ninety adjustment disorder patients were divided into Soyo-san administration and placebo groups and compared for 6 weeks. PSS stress scores decreased by 39% and cortisol awakening response normalized in the Soyo-san group.

Key Conclusion

Soyo-san has effects on regulating the stress response of adjustment disorder at the physiological level.

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Before-After Mental Health

Pre-Post Comparison Study of Combined Auricular Acupuncture and Herbal Medicine for Binge Eating Disorder

Kim GH, Park HJ, Lee SH, et al.

Eating Behaviors (2024)

52% Binge score↓
3.2 kg Weight Reduction
55 subjects Participants

The combination of auricular acupuncture and herbal medicine is effective for binge impulse suppression and weight management.

View Source 2024
Before-After Mental Health

Pre-Post Comparison Study of Combined Auricular Acupuncture and Herbal Medicine for Binge Eating Disorder

Kim GH, Park HJ, Lee SH, et al. Eating Behaviors (2024)
52% Binge score↓
3.2 kg Weight Reduction
55 subjects Participants

Summary

Auricular acupuncture (Shenmen, Stomach point) + herbal medicine (Banhasasim-tang) were applied for 10 weeks to 55 binge eating disorder patients. BES binge eating scores decreased by 52%, and weight decreased by an average of 3.2 kg.

Key Conclusion

The combination of auricular acupuncture and herbal medicine is effective for binge impulse suppression and weight management.

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Narrative Review Mental Health

Polysomnography-Based Effect of Herbal Medicine Prescriptions for Sleep Disorders: A Narrative Review

Choi AR, Lim JH, Han JM, et al.

Sleep Medicine Reviews (2024)

20 sources Reviewed Literature
Latency shortened Sleep Onset Improvement
Slow-wave sleep↑ Sleep Quality Improvement

Herbal medicine prescriptions improve PSG objective sleep indicators and show potential as alternatives to sleep medications.

View Source 2024
Narrative Review Mental Health

Polysomnography-Based Effect of Herbal Medicine Prescriptions for Sleep Disorders: A Narrative Review

Choi AR, Lim JH, Han JM, et al. Sleep Medicine Reviews (2024)
20 sources Reviewed Literature
Latency shortened Sleep Onset Improvement
Slow-wave sleep↑ Sleep Quality Improvement

Summary

Twenty articles on PSG-based effects of herbal medicine prescriptions for sleep disorders were reviewed. Sanjoin-tang and Ondam-tang showed effects on sleep latency shortening and slow-wave sleep increase.

Key Conclusion

Herbal medicine prescriptions improve PSG objective sleep indicators and show potential as alternatives to sleep medications.

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Cross-Sectional Mental Health

Effect of Herbal Medicine (Chongmyung-tang) on Examinee Stress and Concentration: A Cross-Sectional Analysis

Han CH, Go GY, Min BW, et al.

Journal of Korean Medicine (2024)

200 patients Participants
27% Stress reduction
Concentration improved CPT improvement

Chongmyung-tang intake is significantly associated with stress management and improved concentration in examinees.

View Source 2024
Cross-Sectional Mental Health

Effect of Herbal Medicine (Chongmyung-tang) on Examinee Stress and Concentration: A Cross-Sectional Analysis

Han CH, Go GY, Min BW, et al. Journal of Korean Medicine (2024)
200 patients Participants
27% Stress reduction
Concentration improved CPT improvement

Summary

Stress (PSS), concentration (CPT), and academic performance were analyzed in 200 examinees according to their experience taking Chongmyung-tang. The user group showed 27% lower PSS scores and significantly higher CPT attention scores.

Key Conclusion

Chongmyung-tang intake is significantly associated with stress management and improved concentration in examinees.

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RCT Mental Health

Randomized Controlled Trial of Herbal Medicine (Sihosogan-san) for Post-Traumatic Stress Disorder

Shin WC, Kim MJ, Choi HS, et al.

Psychopharmacology (2024)

45% PCL-5 reduction
70 patients Participants
Hyperarousal reduced Key improvement

Sihosogan-san is effective as adjunctive therapy for PTSD in improving hyperarousal and avoidance symptoms.

View Source 2024
RCT Mental Health

Randomized Controlled Trial of Herbal Medicine (Sihosogan-san) for Post-Traumatic Stress Disorder

Shin WC, Kim MJ, Choi HS, et al. Psychopharmacology (2024)
45% PCL-5 reduction
70 patients Participants
Hyperarousal reduced Key improvement

Summary

Seventy PTSD patients were compared between a Sihosogan-san plus standard care group and a standard care alone group over 12 weeks. PCL-5 scores decreased by 45% and hyperarousal symptoms significantly improved in the combination group.

Key Conclusion

Sihosogan-san is effective as adjunctive therapy for PTSD in improving hyperarousal and avoidance symptoms.

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Meta-Analysis Mental Health

Effect of Meditation Combined with Herbal Medicine on Chronic Anxiety: A Meta-Analysis

Kim CH, Baek YH, Jeon SW, et al.

Journal of Psychosomatic Research (2023)

14 RCTs Analyzed RCTs
-4.21 BAI MD
Synergistic effect Combination benefit

The combination of meditation and herbal medicine provides synergistic effects for chronic anxiety.

View Source 2023
Meta-Analysis Mental Health

Effect of Meditation Combined with Herbal Medicine on Chronic Anxiety: A Meta-Analysis

Kim CH, Baek YH, Jeon SW, et al. Journal of Psychosomatic Research (2023)
14 RCTs Analyzed RCTs
-4.21 BAI MD
Synergistic effect Combination benefit

Summary

Fourteen RCTs evaluating the combined effects of meditation and herbal medicine on chronic anxiety were meta-analyzed. The combination group showed additional BAI score reduction (MD: -4.21) compared to monotherapy.

Key Conclusion

The combination of meditation and herbal medicine provides synergistic effects for chronic anxiety.

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RCT Mental Health

Randomized Controlled Trial of Moxibustion Combined with Herbal Medicine for Sleep Disorders in the Elderly

Seo DW, Park BS, Lee SY, et al.

Geriatrics & Gerontology International (2024)

6.2 points PSQI reduction
80 patients Participants
Moxibustion + herbs Optimal combination

Combination of moxibustion and herbal medicine is more effective than monotherapy for sleep disorders in the elderly.

View Source 2024
RCT Mental Health

Randomized Controlled Trial of Moxibustion Combined with Herbal Medicine for Sleep Disorders in the Elderly

Seo DW, Park BS, Lee SY, et al. Geriatrics & Gerontology International (2024)
6.2 points PSQI reduction
80 patients Participants
Moxibustion + herbs Optimal combination

Summary

Eighty elderly patients aged 65 or older with sleep disorders were compared between a moxibustion plus herbal medicine group and herbal medicine alone group for 8 weeks. The combination group showed a 6.2-point reduction in PSQI, significantly superior to the monotherapy group (3.8 points).

Key Conclusion

Combination of moxibustion and herbal medicine is more effective than monotherapy for sleep disorders in the elderly.

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Narrative Review Mental Health

Narrative Review of Acupuncture Treatment for Post-Stroke Depression

Shin SM, Bae GE, Kim KW, et al.

Journal of Stroke and Cerebrovascular Diseases (2023)

20 sources Reviewed Literature
HAM-D↓ Depression Reduction
Antidepressants↓ Dose Reduction Effect

Acupuncture treatment is useful as an adjunctive treatment for post-stroke depression.

View Source 2023
Narrative Review Mental Health

Narrative Review of Acupuncture Treatment for Post-Stroke Depression

Shin SM, Bae GE, Kim KW, et al. Journal of Stroke and Cerebrovascular Diseases (2023)
20 sources Reviewed Literature
HAM-D↓ Depression Reduction
Antidepressants↓ Dose Reduction Effect

Summary

Twenty articles on the effect of acupuncture treatment for post-stroke depression were reviewed. Acupuncture treatment showed effects on HAM-D reduction and antidepressant dose reduction.

Key Conclusion

Acupuncture treatment is useful as an adjunctive treatment for post-stroke depression.

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Before-After Mental Health

Pre-Post Comparison Study of Auricular Acupuncture for Nocturnal Anxiety Attacks

Moon SJ, Park JY, Han SH, et al.

Journal of Anxiety Disorders (2024)

71% Attack frequency reduction
45 patients Participants
Sleep improved Additional benefit

Auricular acupuncture effectively reduces the frequency and intensity of nocturnal anxiety attacks.

View Source 2024
Before-After Mental Health

Pre-Post Comparison Study of Auricular Acupuncture for Nocturnal Anxiety Attacks

Moon SJ, Park JY, Han SH, et al. Journal of Anxiety Disorders (2024)
71% Attack frequency reduction
45 patients Participants
Sleep improved Additional benefit

Summary

Auricular acupuncture (Shenmen, Heart point, Sympathetic point) was applied to 45 patients with nocturnal anxiety attacks for 6 weeks. Nocturnal attack frequency decreased from 4.1 to 1.2 per week and sleep efficiency improved.

Key Conclusion

Auricular acupuncture effectively reduces the frequency and intensity of nocturnal anxiety attacks.

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Cohort Study Mental Health

Korean Medicine Health Management Utilization and Mental Health in Academically Stressed College Students: A Cohort Study

Yang SB, Kim SH, Lee JA, et al.

BMC Psychiatry (2024)

400 patients Participants
33% Depression reduction
1 year Follow-up period

Korean medicine health management is effective for maintaining mental health and managing academic stress in college students.

View Source 2024
Cohort Study Mental Health

Korean Medicine Health Management Utilization and Mental Health in Academically Stressed College Students: A Cohort Study

Yang SB, Kim SH, Lee JA, et al. BMC Psychiatry (2024)
400 patients Participants
33% Depression reduction
1 year Follow-up period

Summary

Four hundred college students were followed for one year, divided into Korean medicine health management users and non-users. Users showed significantly lower PHQ-9 (-33%), GAD-7 (-29%), and academic stress (-25%).

Key Conclusion

Korean medicine health management is effective for maintaining mental health and managing academic stress in college students.

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Narrative Review Mental Health

Narrative Review of Korean Medicine for Adjustment Disorder Following Divorce or Bereavement

Kang YH, Kim DH, Lim BV, et al.

Bereavement Care (2024)

12 studies Reviewed papers
Grief reduced Emotional recovery
Gamisoyo-san Representative formula

Korean medicine is a complementary approach supporting emotional recovery from adjustment disorder after loss.

View Source 2024
Narrative Review Mental Health

Narrative Review of Korean Medicine for Adjustment Disorder Following Divorce or Bereavement

Kang YH, Kim DH, Lim BV, et al. Bereavement Care (2024)
12 studies Reviewed papers
Grief reduced Emotional recovery
Gamisoyo-san Representative formula

Summary

Twelve papers on Korean medicine for adjustment disorder following divorce or bereavement were reviewed. Combination of herbal medicine (Gamisoyo-san, Gwibi-tang) with acupuncture showed efficacy in alleviating grief reactions and depressive symptoms.

Key Conclusion

Korean medicine is a complementary approach supporting emotional recovery from adjustment disorder after loss.

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