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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 84 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Systematic Review Men's Health / Urology

Analgesic Effect of Combined Electroacupuncture and Moxibustion Treatment for Testicular Pain: A Systematic Review

김성준, 박현우, 장태호, et al.

Pain Medicine (2023)

3.4 points NRS Pain Reduction
312 subjects Total Subjects
8 studies Included Studies

Combined electroacupuncture-moxibustion treatment is an effective non-pharmacological analgesic therapy for chronic testicular pain and contributes to alleviating neuropathic pain mechanisms.

View Source 2023
Systematic Review Men's Health / Urology

Analgesic Effect of Combined Electroacupuncture and Moxibustion Treatment for Testicular Pain: A Systematic Review

김성준, 박현우, 장태호, et al. Pain Medicine (2023)
3.4 points NRS Pain Reduction
312 subjects Total Subjects
8 studies Included Studies

Summary

A systematic review analyzing the analgesic effect of combined electroacupuncture and moxibustion treatment in chronic testicular pain patients. Eight clinical trials (total 312 subjects) were included, and the combined electroacupuncture-moxibustion group showed an average NRS pain score reduction of 3.4 points, with significantly reduced analgesic usage. Daedun and Gwirae acupoints were the main selected points.

Key Conclusion

Combined electroacupuncture-moxibustion treatment is an effective non-pharmacological analgesic therapy for chronic testicular pain and contributes to alleviating neuropathic pain mechanisms.

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Narrative Review Men's Health / Urology

Semen Parameter Improvement with Korean Medicine Treatment for Varicocele-Associated Male Infertility: A Narrative Literature Review

서영민, 김도형, 이준석, et al.

Reproductive BioMedicine Online (2024)

28 studies Analyzed Studies
34.5% Natural Pregnancy Rate (Herbal Group)
10 years Analysis Period

Korean medicine treatment is promising as non-surgical management of varicocele-associated male infertility and as adjunctive treatment for surgery, and large-scale clinical trials are needed.

View Source 2024
Narrative Review Men's Health / Urology

Semen Parameter Improvement with Korean Medicine Treatment for Varicocele-Associated Male Infertility: A Narrative Literature Review

서영민, 김도형, 이준석, et al. Reproductive BioMedicine Online (2024)
28 studies Analyzed Studies
34.5% Natural Pregnancy Rate (Herbal Group)
10 years Analysis Period

Summary

A narrative literature review comprehensively analyzing Korean medicine treatment research for varicocele-associated male infertility. Analysis of 28 studies confirmed that Gyejibongnyong-hwan-based herbal medicine was effective for improving varicocele grade and semen parameters, and herbal medicine combination before and after surgery additionally improved pregnancy rates.

Key Conclusion

Korean medicine treatment is promising as non-surgical management of varicocele-associated male infertility and as adjunctive treatment for surgery, and large-scale clinical trials are needed.

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Before-After Men's Health / Urology

Effect of Ugwiyin on Energy Metabolism Improvement in Vitality Decline and Yang Deficiency: A Pre-Post Comparison Study

정승호, 최원석, 양지훈, et al.

Journal of Ginseng Research (2024)

61.2% Fatigue Reduction Rate
62 subjects Number of Subjects
p<0.001 Statistical Significance

Ugwiyin activates cellular energy metabolism in yang deficiency men and significantly improves subjective fatigue.

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Before-After Men's Health / Urology

Effect of Ugwiyin on Energy Metabolism Improvement in Vitality Decline and Yang Deficiency: A Pre-Post Comparison Study

정승호, 최원석, 양지훈, et al. Journal of Ginseng Research (2024)
61.2% Fatigue Reduction Rate
62 subjects Number of Subjects
p<0.001 Statistical Significance

Summary

A pre-post comparison study analyzing the effect of Ugwiyin on energy metabolism improvement in 62 men complaining of vitality decline and yang deficiency. After 8 weeks of administration, blood CoQ10 and ATP production capacity increased significantly, and thyroid function indicators (fT3, fT4) also increased within normal ranges. VAS fatigue scores decreased by an average of 61.2%.

Key Conclusion

Ugwiyin activates cellular energy metabolism in yang deficiency men and significantly improves subjective fatigue.

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Cross-Sectional Men's Health / Urology

Effect of Gyeongokgo on Fatigue and Physical Strength Improvement in Male Chronic Fatigue: A Cross-Sectional Study

오태준, 김병수, 이재민, et al.

한방재활의학과학회지 (2023)

42.6% FSS Score Reduction Rate
76 subjects Number of Subjects
p<0.01 Statistical Significance

Gyeongokgo significantly improves subjective fatigue and objective physical strength indicators in male chronic fatigue patients.

View Source 2023
Cross-Sectional Men's Health / Urology

Effect of Gyeongokgo on Fatigue and Physical Strength Improvement in Male Chronic Fatigue: A Cross-Sectional Study

오태준, 김병수, 이재민, et al. 한방재활의학과학회지 (2023)
42.6% FSS Score Reduction Rate
76 subjects Number of Subjects
p<0.01 Statistical Significance

Summary

A cross-sectional study analyzing the effect of Gyeongokgo on fatigue and physical strength improvement in 76 men complaining of chronic fatigue. After 8 weeks of Gyeongokgo intake, Fatigue Severity Scale (FSS) scores decreased from an average of 5.4 to 3.1, and physical strength indicators such as grip strength and 6-minute walking distance also improved significantly.

Key Conclusion

Gyeongokgo significantly improves subjective fatigue and objective physical strength indicators in male chronic fatigue patients.

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Cohort Study Men's Health / Urology

Effect of Acupuncture Treatment on Male Job Stress and Autonomic Nervous System Imbalance: A Cohort Study

한재욱, 신현정, 박용석, et al.

Stress and Health (2024)

28.7% LF/HF Ratio Improvement
104 subjects Cohort Size
8 weeks Treatment Period

Acupuncture treatment effectively corrects autonomic nervous system imbalance due to male job stress and contributes to stress hormone regulation.

View Source 2024
Cohort Study Men's Health / Urology

Effect of Acupuncture Treatment on Male Job Stress and Autonomic Nervous System Imbalance: A Cohort Study

한재욱, 신현정, 박용석, et al. Stress and Health (2024)
28.7% LF/HF Ratio Improvement
104 subjects Cohort Size
8 weeks Treatment Period

Summary

A cohort study analyzing the autonomic nervous system regulation effect of acupuncture treatment in 104 male office workers showing high job stress. After 8 weeks of acupuncture treatment twice weekly, the LF/HF ratio of heart rate variability (HRV) improved significantly, and cortisol awakening response (CAR) also normalized. Job stress scale (KOSS) scores also decreased significantly.

Key Conclusion

Acupuncture treatment effectively corrects autonomic nervous system imbalance due to male job stress and contributes to stress hormone regulation.

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RCT Men's Health / Urology

Antidepressant Effect of Guibi-tang on Male Climacteric Depression: A Randomized Controlled Trial

곽재현, 문지영, 차승환, et al.

Journal of Affective Disorders (2023)

49.3% BDI Score Reduction Rate
82 subjects Number of Subjects
p<0.001 Statistical Significance

Guibi-tang significantly alleviates depressive symptoms in male climacteric depression patients, and BDNF-mediated neuroplasticity enhancement is suggested as the mechanism.

View Source 2023
RCT Men's Health / Urology

Antidepressant Effect of Guibi-tang on Male Climacteric Depression: A Randomized Controlled Trial

곽재현, 문지영, 차승환, et al. Journal of Affective Disorders (2023)
49.3% BDI Score Reduction Rate
82 subjects Number of Subjects
p<0.001 Statistical Significance

Summary

A randomized controlled trial evaluating the antidepressant effect of Guibi-tang in 82 patients with male climacteric depression (BDI ≥14, AMS ≥37). After 12 weeks of administration, BDI scores decreased from an average of 21.3 to 10.8, and serum BDNF levels increased significantly. AMS scores also improved simultaneously.

Key Conclusion

Guibi-tang significantly alleviates depressive symptoms in male climacteric depression patients, and BDNF-mediated neuroplasticity enhancement is suggested as the mechanism.

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Meta-Analysis Men's Health / Urology

Weight and Body Composition Changes with Combined Acupuncture-Electroacupuncture Treatment for Male Obesity: A Meta-Analysis

이진혁, 송민호, 황재우, et al.

Acupuncture in Medicine (2024)

3.8 kg Average Weight Reduction
2.9% Body Fat Percentage Reduction
756 subjects Total Subjects

Combined acupuncture-electroacupuncture treatment is effective for weight and body composition improvement in male obesity patients, and synergistic effects are expected when combined with lifestyle modification.

View Source 2024
Meta-Analysis Men's Health / Urology

Weight and Body Composition Changes with Combined Acupuncture-Electroacupuncture Treatment for Male Obesity: A Meta-Analysis

이진혁, 송민호, 황재우, et al. Acupuncture in Medicine (2024)
3.8 kg Average Weight Reduction
2.9% Body Fat Percentage Reduction
756 subjects Total Subjects

Summary

A meta-analysis analyzing weight and body composition changes with combined acupuncture-electroacupuncture treatment in men with BMI 25 or higher. Twelve randomized controlled trials (total 756 subjects) were included, confirming an average weight reduction of 3.8 kg and body fat percentage reduction of 2.9% in the treatment group. Electroacupuncture centered on abdominal acupoints was most effective.

Key Conclusion

Combined acupuncture-electroacupuncture treatment is effective for weight and body composition improvement in male obesity patients, and synergistic effects are expected when combined with lifestyle modification.

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Systematic Review Men's Health / Urology

Effect of Bangpungtongseong-san on Visceral Fat Reduction for Male Abdominal Obesity: A Systematic Review and Meta-Analysis

장서진, 김민규, 이하은, et al.

Obesity Reviews (2024)

4.7 cm Waist Circumference Reduction
23.4 cm² Visceral Fat Area Reduction
1,089 subjects Total Subjects

Bangpungtongseong-san significantly reduces visceral fat in male abdominal obesity patients and is also effective for improving metabolic syndrome risk factors.

View Source 2024
Systematic Review Men's Health / Urology

Effect of Bangpungtongseong-san on Visceral Fat Reduction for Male Abdominal Obesity: A Systematic Review and Meta-Analysis

장서진, 김민규, 이하은, et al. Obesity Reviews (2024)
4.7 cm Waist Circumference Reduction
23.4 cm² Visceral Fat Area Reduction
1,089 subjects Total Subjects

Summary

A systematic review and meta-analysis analyzing the effect of Bangpungtongseong-san on visceral fat reduction in men with abdominal obesity. Sixteen clinical trials (total 1,089 subjects) were included, and the Bangpungtongseong-san administration group showed an average waist circumference reduction of 4.7 cm and visceral fat area reduction of 23.4 cm².

Key Conclusion

Bangpungtongseong-san significantly reduces visceral fat in male abdominal obesity patients and is also effective for improving metabolic syndrome risk factors.

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Narrative Review Men's Health / Urology

Efficacy and Safety of Korean Medicine Treatment for Male Hair Loss: A Narrative Literature Review

나승현, 전호영, 백지원, et al.

Dermatologic Therapy (2023)

38 studies Analyzed Studies
2.3% Adverse Reaction Rate
15 years Analysis Period

Korean medicine treatment is an effective and safe treatment alternative for male hair loss and can be particularly recommended for patients concerned about drug side effects.

View Source 2023
Narrative Review Men's Health / Urology

Efficacy and Safety of Korean Medicine Treatment for Male Hair Loss: A Narrative Literature Review

나승현, 전호영, 백지원, et al. Dermatologic Therapy (2023)
38 studies Analyzed Studies
2.3% Adverse Reaction Rate
15 years Analysis Period

Summary

A narrative literature review comprehensively analyzing the efficacy and safety of Korean medicine treatment (herbal medicine, acupuncture, pharmacopuncture, scalp acupuncture) for male hair loss. Thirty-eight clinical studies over the past 15 years were analyzed, with combined herbal medicine and pharmacopuncture treatment showing the highest effects, and adverse reaction incidence rates significantly lower than finasteride.

Key Conclusion

Korean medicine treatment is an effective and safe treatment alternative for male hair loss and can be particularly recommended for patients concerned about drug side effects.

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Case Study Men's Health / Urology

Hair Regrowth Effect of Pharmacopuncture Treatment for Androgenetic Alopecia (AGA): 12 Case Reports

양현수, 오지훈, 김래환, et al.

대한한방피부미용학회지 (2024)

18.7 strands/cm² Hair Density Increase
12 cases Number of Cases
16 weeks Treatment Period

Polygoni Multiflori Radix-Biota Orientalis pharmacopuncture is effective for improving hair density and thickness in androgenetic alopecia patients, with scalp microcirculation improvement as the main mechanism.

View Source 2024
Case Study Men's Health / Urology

Hair Regrowth Effect of Pharmacopuncture Treatment for Androgenetic Alopecia (AGA): 12 Case Reports

양현수, 오지훈, 김래환, et al. 대한한방피부미용학회지 (2024)
18.7 strands/cm² Hair Density Increase
12 cases Number of Cases
16 weeks Treatment Period

Summary

A case report on 12 patients with androgenetic alopecia (AGA, Hamilton-Norwood classification III-IV) treated with Polygoni Multiflori Radix-Biota Orientalis pharmacopuncture. After 16 weeks of scalp pharmacopuncture twice weekly, hair density increased by an average of 18.7 strands/cm², and hair thickness also increased significantly. Scalp blood flow improvement was confirmed by ultrasound examination.

Key Conclusion

Polygoni Multiflori Radix-Biota Orientalis pharmacopuncture is effective for improving hair density and thickness in androgenetic alopecia patients, with scalp microcirculation improvement as the main mechanism.

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Before-After Men's Health / Urology

Anti-Inflammatory and Voiding Function Improvement Effect of Oryeong-san on Male Cystitis: A Pre-Post Comparison Study

최동헌, 김세준, 이우택, et al.

Complementary Therapies in Clinical Practice (2023)

2.1 days Symptom Resolution Shortened
44 subjects Number of Subjects
p=0.012 Statistical Significance

Oryeong-san is effective for promoting inflammation resolution and shortening symptom improvement period as adjunctive to antibiotic treatment for male cystitis.

View Source 2023
Before-After Men's Health / Urology

Anti-Inflammatory and Voiding Function Improvement Effect of Oryeong-san on Male Cystitis: A Pre-Post Comparison Study

최동헌, 김세준, 이우택, et al. Complementary Therapies in Clinical Practice (2023)
2.1 days Symptom Resolution Shortened
44 subjects Number of Subjects
p=0.012 Statistical Significance

Summary

A pre-post comparison study analyzing the anti-inflammatory and voiding function improvement effect of Oryeong-san in 44 male patients with acute cystitis. With combined antibiotic administration, the Oryeong-san addition group showed faster urinary WBC reduction speed, and dysuria resolution period was shortened by an average of 2.1 days, with lower recurrence rates.

Key Conclusion

Oryeong-san is effective for promoting inflammation resolution and shortening symptom improvement period as adjunctive to antibiotic treatment for male cystitis.

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Cross-Sectional Men's Health / Urology

Immune Regulatory Effect of Bojungikgi-tang on Recurrent Urinary Tract Infections in Men: A Cross-Sectional Study

권정민, 유승호, 장동수, et al.

BMC Urology (2024)

68.9% Recurrence Rate Reduction
58 subjects Number of Subjects
12 months Follow-up Period

Bojungikgi-tang is effective for preventing recurrent urinary tract infections in men, and a mechanism through urinary mucosal local immune enhancement was confirmed.

View Source 2024
Cross-Sectional Men's Health / Urology

Immune Regulatory Effect of Bojungikgi-tang on Recurrent Urinary Tract Infections in Men: A Cross-Sectional Study

권정민, 유승호, 장동수, et al. BMC Urology (2024)
68.9% Recurrence Rate Reduction
58 subjects Number of Subjects
12 months Follow-up Period

Summary

A cross-sectional study analyzing the immune regulatory effect of Bojungikgi-tang in 58 men with recurrent urinary tract infections (≥3/year). The Bojungikgi-tang administration group showed increased IgA secretion in urine, and expression of urinary mucosal defense factor Tamm-Horsfall protein also improved. Recurrence rates decreased significantly at 12-month follow-up.

Key Conclusion

Bojungikgi-tang is effective for preventing recurrent urinary tract infections in men, and a mechanism through urinary mucosal local immune enhancement was confirmed.

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