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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 84 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Narrative Review Men's Health / Urology

Korean Medicine Integrated Treatment for Quality of Life Improvement in Prostatitis Patients: A Narrative Literature Review

류동우, 전승범, 김한솔, et al.

Quality of Life Research (2024)

32 studies Analyzed Studies
67.8% QoL Improvement Rate
p<0.05 Statistical Significance

Korean medicine integrated treatment enables a multidimensional approach to quality of life improvement in prostatitis patients and is an effective complementary therapy to drug treatment.

View Source 2024
Narrative Review Men's Health / Urology

Korean Medicine Integrated Treatment for Quality of Life Improvement in Prostatitis Patients: A Narrative Literature Review

류동우, 전승범, 김한솔, et al. Quality of Life Research (2024)
32 studies Analyzed Studies
67.8% QoL Improvement Rate
p<0.05 Statistical Significance

Summary

A narrative literature review analyzing the Korean medicine integrated treatment approach for quality of life improvement in prostatitis patients. Analysis of 32 studies showed that combined herbal medicine-acupuncture-moxibustion treatment showed superior improvement in NIH-CPSI QoL domain compared with drug alone, with significant effects also confirmed in psychological stress reduction.

Key Conclusion

Korean medicine integrated treatment enables a multidimensional approach to quality of life improvement in prostatitis patients and is an effective complementary therapy to drug treatment.

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RCT Men's Health / Urology

Effect of Yang-Tonifying Prescriptions on Erectile Dysfunction with Testosterone Deficiency: A Randomized Controlled Trial

한동혁, 오승진, 김민태, et al.

Asian Journal of Andrology (2023)

1.9 ng/mL Testosterone Increase
6.4 points IIEF-5 Improvement
68 subjects Number of Subjects

Yang-tonifying prescriptions are an effective treatment that simultaneously improves both hormone and sexual function aspects of erectile dysfunction with testosterone deficiency.

View Source 2023
RCT Men's Health / Urology

Effect of Yang-Tonifying Prescriptions on Erectile Dysfunction with Testosterone Deficiency: A Randomized Controlled Trial

한동혁, 오승진, 김민태, et al. Asian Journal of Andrology (2023)
1.9 ng/mL Testosterone Increase
6.4 points IIEF-5 Improvement
68 subjects Number of Subjects

Summary

A randomized controlled trial evaluating the effect of yang-tonifying prescriptions (combined deer antler, Epimedium, Cuscuta) in 68 patients with erectile dysfunction with testosterone deficiency. After 16 weeks of administration, total testosterone increased by an average of 1.9 ng/mL, and IIEF-5 scores also improved by an average of 6.4 points. A significant positive correlation between both indicators was confirmed.

Key Conclusion

Yang-tonifying prescriptions are an effective treatment that simultaneously improves both hormone and sexual function aspects of erectile dysfunction with testosterone deficiency.

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Cross-Sectional Men's Health / Urology

Bladder Function Improvement with Moxibustion Treatment in Overactive Bladder Men: A Cross-Sectional Analysis

문재호, 김지현, 이승환, et al.

대한침구의학회지 (2023)

31.6% Urination Frequency Reduction Rate
54 subjects Number of Subjects
8 weeks Treatment Period

Moxibustion treatment effectively reduces urinary frequency and urgency in overactive bladder male patients and improves bladder storage function.

View Source 2023
Cross-Sectional Men's Health / Urology

Bladder Function Improvement with Moxibustion Treatment in Overactive Bladder Men: A Cross-Sectional Analysis

문재호, 김지현, 이승환, et al. 대한침구의학회지 (2023)
31.6% Urination Frequency Reduction Rate
54 subjects Number of Subjects
8 weeks Treatment Period

Summary

A cross-sectional study analyzing the bladder function improvement effect of moxibustion treatment at Gwanwon, Junggeuk, and Gihae acupoints in 54 men with overactive bladder symptoms. After 8 weeks of moxibustion treatment 3 times weekly, daily urination frequency on voiding diary decreased from an average of 11.4 to 7.8 times, and urgency frequency also decreased significantly. Functional bladder capacity on bladder ultrasound increased.

Key Conclusion

Moxibustion treatment effectively reduces urinary frequency and urgency in overactive bladder male patients and improves bladder storage function.

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Before-After Men's Health / Urology

Combined Electroacupuncture-Exercise Treatment for Male Pelvic Floor Muscle Function Enhancement: A Pre-Post Comparison Study

구현우, 손태영, 장성민, et al.

Neurourology and Urodynamics (2024)

38.4% Pelvic Floor Muscle Contractility Increase
42 subjects Number of Subjects
10 weeks Treatment Period

Combined electroacupuncture-pelvic floor muscle exercise treatment is effective for strengthening muscle strength and improving urinary control in male pelvic floor dysfunction patients.

View Source 2024
Before-After Men's Health / Urology

Combined Electroacupuncture-Exercise Treatment for Male Pelvic Floor Muscle Function Enhancement: A Pre-Post Comparison Study

구현우, 손태영, 장성민, et al. Neurourology and Urodynamics (2024)
38.4% Pelvic Floor Muscle Contractility Increase
42 subjects Number of Subjects
10 weeks Treatment Period

Summary

A pre-post comparison study analyzing the effect of combined electroacupuncture-pelvic floor muscle exercise treatment in 42 men complaining of post-void dribbling and stress urinary incontinence. After 10 weeks of treatment, pelvic floor muscle contractility (EMG) increased by an average of 38.4%, and dribbling frequency decreased significantly. Perineal electroacupuncture stimulation promoted muscle re-education.

Key Conclusion

Combined electroacupuncture-pelvic floor muscle exercise treatment is effective for strengthening muscle strength and improving urinary control in male pelvic floor dysfunction patients.

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Case Study Men's Health / Urology

Case Report of 8 Successful Natural Pregnancies After Korean Medicine Treatment in Male Infertility Couples

황준석, 나경희, 정이현, et al.

Journal of Alternative and Complementary Medicine (2023)

75.0% Natural Pregnancy Success Rate
8 couples Number of Cases
6-9 months Treatment Period

Korean medicine treatment can contribute to natural pregnancy achievement in male infertility couples after assisted reproductive technology failure, and personalized pattern-based treatment is key.

View Source 2023
Case Study Men's Health / Urology

Case Report of 8 Successful Natural Pregnancies After Korean Medicine Treatment in Male Infertility Couples

황준석, 나경희, 정이현, et al. Journal of Alternative and Complementary Medicine (2023)
75.0% Natural Pregnancy Success Rate
8 couples Number of Cases
6-9 months Treatment Period

Summary

A case report on 8 male infertility couples who switched to Korean medicine treatment after assisted reproductive technology failure. After 6-9 months of administering pattern-based herbal medicine (Ojayeonjong-hwan, Gwirokbocheon-tang) and acupuncture treatment to men, 6 out of 8 couples (75%) successfully achieved natural pregnancy. Semen parameter improvements were significantly associated with pregnancy success.

Key Conclusion

Korean medicine treatment can contribute to natural pregnancy achievement in male infertility couples after assisted reproductive technology failure, and personalized pattern-based treatment is key.

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Narrative Review Men's Health / Urology

Evidence for Korean Medicine Tonifying Therapy for Male Health Enhancement: A Narrative Literature Review

이용석, 김현준, 박소연, et al.

Nutrients (2024)

45 studies Analyzed Studies
4 domains Health Indicator Categories
15 years Analysis Period

Korean medicine tonifying therapy exerts multidimensional effects on overall health enhancement in middle-aged and older men and has high utility value in preventive medicine.

View Source 2024
Narrative Review Men's Health / Urology

Evidence for Korean Medicine Tonifying Therapy for Male Health Enhancement: A Narrative Literature Review

이용석, 김현준, 박소연, et al. Nutrients (2024)
45 studies Analyzed Studies
4 domains Health Indicator Categories
15 years Analysis Period

Summary

A narrative literature review comprehensively analyzing the clinical evidence for Korean medicine tonifying therapy (Bojungikgi-tang, Sipjeondaebo-tang, Gyeongokgo, deer antler combined formula, etc.) for middle-aged and older male health enhancement. Forty-five studies were analyzed, confirming evidence that tonifying herbal medicine improves multidimensional health indicators including fatigue, sexual function, immunity, and musculoskeletal function.

Key Conclusion

Korean medicine tonifying therapy exerts multidimensional effects on overall health enhancement in middle-aged and older men and has high utility value in preventive medicine.

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Systematic Review Men's Health / Urology

Effect and Safety of Pharmacopuncture Treatment for Male Lower Urinary Tract Symptoms: A Systematic Review and Meta-Analysis

백승호, 전민석, 김도연, et al.

Frontiers in Pharmacology (2024)

5.1 points IPSS Reduction
847 subjects Total Subjects
4.7% Adverse Reaction Rate

Pharmacopuncture treatment is an effective and safe treatment for male LUTS, and additional improvement effects can be expected when combined with existing treatments.

View Source 2024
Systematic Review Men's Health / Urology

Effect and Safety of Pharmacopuncture Treatment for Male Lower Urinary Tract Symptoms: A Systematic Review and Meta-Analysis

백승호, 전민석, 김도연, et al. Frontiers in Pharmacology (2024)
5.1 points IPSS Reduction
847 subjects Total Subjects
4.7% Adverse Reaction Rate

Summary

A systematic review and meta-analysis analyzing the effect and safety of pharmacopuncture treatment for male lower urinary tract symptoms (LUTS). Thirteen clinical trials (total 847 subjects) were included, and the bee venom and wild ginseng pharmacopuncture administration group showed an average IPSS reduction of 5.1 points, with significant prostate volume reduction also confirmed. Adverse reaction incidence was mild at 4.7%.

Key Conclusion

Pharmacopuncture treatment is an effective and safe treatment for male LUTS, and additional improvement effects can be expected when combined with existing treatments.

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Before-After Men's Health / Urology

Effect of Ugwiyin on Energy Metabolism Improvement in Vitality Decline and Yang Deficiency: A Pre-Post Comparison Study

정승호, 최원석, 양지훈, et al.

Journal of Ginseng Research (2024)

61.2% Fatigue Reduction Rate
62 subjects Number of Subjects
p<0.001 Statistical Significance

Ugwiyin activates cellular energy metabolism in yang deficiency men and significantly improves subjective fatigue.

View Source 2024
Before-After Men's Health / Urology

Effect of Ugwiyin on Energy Metabolism Improvement in Vitality Decline and Yang Deficiency: A Pre-Post Comparison Study

정승호, 최원석, 양지훈, et al. Journal of Ginseng Research (2024)
61.2% Fatigue Reduction Rate
62 subjects Number of Subjects
p<0.001 Statistical Significance

Summary

A pre-post comparison study analyzing the effect of Ugwiyin on energy metabolism improvement in 62 men complaining of vitality decline and yang deficiency. After 8 weeks of administration, blood CoQ10 and ATP production capacity increased significantly, and thyroid function indicators (fT3, fT4) also increased within normal ranges. VAS fatigue scores decreased by an average of 61.2%.

Key Conclusion

Ugwiyin activates cellular energy metabolism in yang deficiency men and significantly improves subjective fatigue.

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Narrative Review Men's Health / Urology

Semen Parameter Improvement with Korean Medicine Treatment for Varicocele-Associated Male Infertility: A Narrative Literature Review

서영민, 김도형, 이준석, et al.

Reproductive BioMedicine Online (2024)

28 studies Analyzed Studies
34.5% Natural Pregnancy Rate (Herbal Group)
10 years Analysis Period

Korean medicine treatment is promising as non-surgical management of varicocele-associated male infertility and as adjunctive treatment for surgery, and large-scale clinical trials are needed.

View Source 2024
Narrative Review Men's Health / Urology

Semen Parameter Improvement with Korean Medicine Treatment for Varicocele-Associated Male Infertility: A Narrative Literature Review

서영민, 김도형, 이준석, et al. Reproductive BioMedicine Online (2024)
28 studies Analyzed Studies
34.5% Natural Pregnancy Rate (Herbal Group)
10 years Analysis Period

Summary

A narrative literature review comprehensively analyzing Korean medicine treatment research for varicocele-associated male infertility. Analysis of 28 studies confirmed that Gyejibongnyong-hwan-based herbal medicine was effective for improving varicocele grade and semen parameters, and herbal medicine combination before and after surgery additionally improved pregnancy rates.

Key Conclusion

Korean medicine treatment is promising as non-surgical management of varicocele-associated male infertility and as adjunctive treatment for surgery, and large-scale clinical trials are needed.

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Systematic Review Men's Health / Urology

Analgesic Effect of Combined Electroacupuncture and Moxibustion Treatment for Testicular Pain: A Systematic Review

김성준, 박현우, 장태호, et al.

Pain Medicine (2023)

3.4 points NRS Pain Reduction
312 subjects Total Subjects
8 studies Included Studies

Combined electroacupuncture-moxibustion treatment is an effective non-pharmacological analgesic therapy for chronic testicular pain and contributes to alleviating neuropathic pain mechanisms.

View Source 2023
Systematic Review Men's Health / Urology

Analgesic Effect of Combined Electroacupuncture and Moxibustion Treatment for Testicular Pain: A Systematic Review

김성준, 박현우, 장태호, et al. Pain Medicine (2023)
3.4 points NRS Pain Reduction
312 subjects Total Subjects
8 studies Included Studies

Summary

A systematic review analyzing the analgesic effect of combined electroacupuncture and moxibustion treatment in chronic testicular pain patients. Eight clinical trials (total 312 subjects) were included, and the combined electroacupuncture-moxibustion group showed an average NRS pain score reduction of 3.4 points, with significantly reduced analgesic usage. Daedun and Gwirae acupoints were the main selected points.

Key Conclusion

Combined electroacupuncture-moxibustion treatment is an effective non-pharmacological analgesic therapy for chronic testicular pain and contributes to alleviating neuropathic pain mechanisms.

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RCT Men's Health / Urology

Effect of Jwagwiyin on Bone Mineral Density Improvement for Male Osteoporosis: A Randomized Controlled Trial

박성현, 노영진, 최준영, et al.

Osteoporosis International (2023)

3.2% Lumbar BMD Increase
74 subjects Number of Subjects
24 weeks Treatment Period

Jwagwiyin significantly improves bone mineral density in male osteoporosis patients, with dual action of promoting bone formation and inhibiting bone resorption confirmed.

View Source 2023
RCT Men's Health / Urology

Effect of Jwagwiyin on Bone Mineral Density Improvement for Male Osteoporosis: A Randomized Controlled Trial

박성현, 노영진, 최준영, et al. Osteoporosis International (2023)
3.2% Lumbar BMD Increase
74 subjects Number of Subjects
24 weeks Treatment Period

Summary

A randomized controlled trial evaluating the effect of Jwagwiyin on bone mineral density improvement in 74 male osteoporosis patients (T-score ≤-2.5). After 24 weeks of Jwagwiyin administration with calcium/vitamin D combination, lumbar BMD increased by an average of 3.2%, and bone metabolism markers (P1NP, CTx) also improved significantly.

Key Conclusion

Jwagwiyin significantly improves bone mineral density in male osteoporosis patients, with dual action of promoting bone formation and inhibiting bone resorption confirmed.

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Cohort Study Men's Health / Urology

Effect of Deer Antler-Red Ginseng Combined Formula on Muscle Strength and Muscle Mass Improvement for Male Sarcopenia: A Cohort Study

강태민, 서재환, 이상혁, et al.

Journal of Cachexia, Sarcopenia and Muscle (2024)

0.38 kg/m² ASMI Increase
88 subjects Cohort Size
16 weeks Treatment Period

Deer antler-red ginseng combined formula significantly improves muscle mass and muscle function in male sarcopenia patients, with IGF-1 pathway activation as the main mechanism.

View Source 2024
Cohort Study Men's Health / Urology

Effect of Deer Antler-Red Ginseng Combined Formula on Muscle Strength and Muscle Mass Improvement for Male Sarcopenia: A Cohort Study

강태민, 서재환, 이상혁, et al. Journal of Cachexia, Sarcopenia and Muscle (2024)
0.38 kg/m² ASMI Increase
88 subjects Cohort Size
16 weeks Treatment Period

Summary

A cohort study analyzing the effect of deer antler-red ginseng combined formula on muscle strength and muscle mass improvement in 88 men diagnosed with sarcopenia (EWGSOP2 criteria). After 16 weeks of administration, appendicular skeletal muscle index (ASMI) increased by an average of 0.38 kg/m², and grip strength and chair-rise speed also improved significantly. IGF-1 levels also increased.

Key Conclusion

Deer antler-red ginseng combined formula significantly improves muscle mass and muscle function in male sarcopenia patients, with IGF-1 pathway activation as the main mechanism.

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