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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 93 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Cohort Study ENT Disorders

Cohort Study of Eungyo-san Combined with Gamgil-tang in Recurrent Tonsillitis Patients

Yoon SJ, Kang BM, Cho NR, et al.

BMC Complementary Medicine and Therapies (2021)

63.2% Recurrence Reduction Rate
180 subjects Participants
6 months Follow-up Period

Eungyo-san combined with Gamgil-tang is effective in preventing tonsillitis recurrence and may serve as an alternative treatment to reduce antibiotic use frequency.

View Source 2021
Cohort Study ENT Disorders

Cohort Study of Eungyo-san Combined with Gamgil-tang in Recurrent Tonsillitis Patients

Yoon SJ, Kang BM, Cho NR, et al. BMC Complementary Medicine and Therapies (2021)
63.2% Recurrence Reduction Rate
180 subjects Participants
6 months Follow-up Period

Summary

One hundred eighty patients with recurrent tonsillitis were divided into Eungyo-san plus Gamgil-tang treatment (90 patients) and conventional treatment (90 patients) groups, followed for 6 months. The herbal treatment group showed significantly fewer tonsillitis recurrences.

Key Conclusion

Eungyo-san combined with Gamgil-tang is effective in preventing tonsillitis recurrence and may serve as an alternative treatment to reduce antibiotic use frequency.

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RCT ENT Disorders

Immunomodulatory Effect of Okbyeongpung-san in Allergic Rhinitis Patients: A Randomized Double-Blind Placebo-Controlled Trial

Park MJ, Shin HK, Lim BS, et al.

Phytomedicine (2023)

78.9% TNSS Improvement Rate
128 subjects Participants
p<0.001 Statistical Significance

Okbyeongpung-san demonstrated significant effects on immunomodulation and symptom alleviation in allergic rhinitis patients.

View Source 2023
RCT ENT Disorders

Immunomodulatory Effect of Okbyeongpung-san in Allergic Rhinitis Patients: A Randomized Double-Blind Placebo-Controlled Trial

Park MJ, Shin HK, Lim BS, et al. Phytomedicine (2023)
78.9% TNSS Improvement Rate
128 subjects Participants
p<0.001 Statistical Significance

Summary

One hundred twenty-eight patients with allergic rhinitis were compared over 12 weeks between Okbyeongpung-san and placebo groups. Serum IgE and eosinophil counts decreased significantly in the treatment group, with marked improvement in Total Nasal Symptom Score (TNSS).

Key Conclusion

Okbyeongpung-san demonstrated significant effects on immunomodulation and symptom alleviation in allergic rhinitis patients.

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Before-After ENT Disorders

Pre-Post Comparison Study of Korean Medicine Combined Treatment for Pediatric Otitis Media

Lee JH, Kim YS, Hwang DS, et al.

Journal of Korean Medicine (2022)

71.1% Tympanic Membrane Improvement Rate
45 subjects Participants
12 weeks Treatment Period

Korean medicine combined treatment can reduce recurrence frequency and contribute to hearing improvement in pediatric recurrent otitis media.

View Source 2022
Before-After ENT Disorders

Pre-Post Comparison Study of Korean Medicine Combined Treatment for Pediatric Otitis Media

Lee JH, Kim YS, Hwang DS, et al. Journal of Korean Medicine (2022)
71.1% Tympanic Membrane Improvement Rate
45 subjects Participants
12 weeks Treatment Period

Summary

Forty-five pediatric patients with recurrent otitis media received combined acupuncture and herbal medicine treatment for 12 weeks. Significant improvements were observed in tympanic membrane findings and audiometric tests after treatment.

Key Conclusion

Korean medicine combined treatment can reduce recurrence frequency and contribute to hearing improvement in pediatric recurrent otitis media.

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RCT ENT Disorders

Randomized Controlled Clinical Trial of Modified Changija-san for Sinusitis Patients

Choi YJ, Seo BK, Han CH, et al.

Complementary Therapies in Medicine (2024)

76.5% Symptom Improvement Rate
96 subjects Participants
8 weeks Treatment Period

Modified Changija-san is an effective Korean medicine treatment for symptom and quality-of-life improvement in chronic sinusitis patients.

View Source 2024
RCT ENT Disorders

Randomized Controlled Clinical Trial of Modified Changija-san for Sinusitis Patients

Choi YJ, Seo BK, Han CH, et al. Complementary Therapies in Medicine (2024)
76.5% Symptom Improvement Rate
96 subjects Participants
8 weeks Treatment Period

Summary

Ninety-six patients with chronic sinusitis were compared over 8 weeks between modified Changija-san and placebo groups. Nasal endoscopic findings and SNOT-22 scores significantly improved in the treatment group. Side effects were limited to 3 cases of mild gastrointestinal disturbance.

Key Conclusion

Modified Changija-san is an effective Korean medicine treatment for symptom and quality-of-life improvement in chronic sinusitis patients.

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Meta-Analysis ENT Disorders

Systematic Review and Meta-analysis of Korean Medicine Rhinitis Treatment Focused on Socheongryong-tang

Kim SH, Park JW, Lee MK, et al.

Evidence-Based Complementary and Alternative Medicine (2023)

82.3% Symptom Improvement Rate
1420 subjects Participants
18 papers Analyzed Papers

Socheongryong-tang is effective in improving major symptoms of allergic rhinitis and can be utilized as a safe treatment with low adverse event rates.

View Source 2023
Meta-Analysis ENT Disorders

Systematic Review and Meta-analysis of Korean Medicine Rhinitis Treatment Focused on Socheongryong-tang

Kim SH, Park JW, Lee MK, et al. Evidence-Based Complementary and Alternative Medicine (2023)
82.3% Symptom Improvement Rate
1420 subjects Participants
18 papers Analyzed Papers

Summary

A systematic review including 18 RCTs was conducted to evaluate the efficacy of Socheongryong-tang for allergic rhinitis. Analysis of 1,420 patients showed significant improvements in major symptoms including nasal congestion, sneezing, and rhinorrhea in the Socheongryong-tang group.

Key Conclusion

Socheongryong-tang is effective in improving major symptoms of allergic rhinitis and can be utilized as a safe treatment with low adverse event rates.

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Before-After ENT Disorders

Clinical Effect of Modified Changija-san for Chronic Sinusitis

Park SJ, Kim SY, Yoo HJ, et al.

American Journal of Rhinology & Allergy (2023)

51% Symptom Score Reduction
38% CT Opacity Improvement
44% Antibiotic Re-prescription Reduction

Modified Changija-san demonstrates significant improvements in both symptoms and imaging findings in chronic sinusitis, with effects in reducing antibiotic reuse.

View Source 2023
Before-After ENT Disorders

Clinical Effect of Modified Changija-san for Chronic Sinusitis

Park SJ, Kim SY, Yoo HJ, et al. American Journal of Rhinology & Allergy (2023)
51% Symptom Score Reduction
38% CT Opacity Improvement
44% Antibiotic Re-prescription Reduction

Summary

A pre-post comparison study was conducted in 82 patients with chronic sinusitis who received modified Changija-san for 12 weeks following antibiotic treatment. SNOT-22 scores decreased by an average of 51%, and CT opacity (Lund-Mackay score) improved by 38%. Antibiotic re-prescription rates were 44% lower than controls.

Key Conclusion

Modified Changija-san demonstrates significant improvements in both symptoms and imaging findings in chronic sinusitis, with effects in reducing antibiotic reuse.

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Meta-Analysis ENT Disorders

Systematic Review and Meta-analysis of Korean Medicine Treatment for Tinnitus

Kim JI, Choi JY, Lee DH, et al.

Complementary Therapies in Medicine (2022)

39% THI Reduction
18 studies Analyzed Studies
1,456 subjects Total Participants

Korean medicine combined treatment significantly improves subjective tinnitus distress and quality of life, and is recommended for patients with insufficient response to conventional therapy.

View Source 2022
Meta-Analysis ENT Disorders

Systematic Review and Meta-analysis of Korean Medicine Treatment for Tinnitus

Kim JI, Choi JY, Lee DH, et al. Complementary Therapies in Medicine (2022)
39% THI Reduction
18 studies Analyzed Studies
1,456 subjects Total Participants

Summary

Eighteen randomized controlled trials (1,456 subjects total) evaluating Korean medicine treatment (acupuncture, herbal medicine, auricular acupuncture) for tinnitus were meta-analyzed. The Korean medicine group demonstrated an average 39% reduction in THI (Tinnitus Handicap Inventory) compared with 19% in controls. Effects were greatest when acupuncture and herbal medicine were combined.

Key Conclusion

Korean medicine combined treatment significantly improves subjective tinnitus distress and quality of life, and is recommended for patients with insufficient response to conventional therapy.

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RCT ENT Disorders

Therapeutic Effect of Acupuncture as Adjunctive Treatment for Sudden Sensorineural Hearing Loss: A Randomized Controlled Trial

Lee JH, Kim HD, Seo YJ, et al.

Otology & Neurotology (2023)

72% Hearing Recovery Rate
45% Complete Recovery Rate
4 weeks Treatment Period

Adjunctive acupuncture increases hearing recovery rates in sudden sensorineural hearing loss, with maximal effects when treatment is initiated early.

View Source 2023
RCT ENT Disorders

Therapeutic Effect of Acupuncture as Adjunctive Treatment for Sudden Sensorineural Hearing Loss: A Randomized Controlled Trial

Lee JH, Kim HD, Seo YJ, et al. Otology & Neurotology (2023)
72% Hearing Recovery Rate
45% Complete Recovery Rate
4 weeks Treatment Period

Summary

Sixty-eight patients with sudden sensorineural hearing loss were compared over 4 weeks between steroid monotherapy and steroid plus acupuncture groups. The combination group demonstrated a hearing recovery rate of 72%, significantly higher than 54% in monotherapy. Notably, when treatment was initiated within 2 weeks of onset, the complete recovery rate reached 45%.

Key Conclusion

Adjunctive acupuncture increases hearing recovery rates in sudden sensorineural hearing loss, with maximal effects when treatment is initiated early.

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RCT ENT Disorders

Therapeutic Effect of Socheongryong-tang on Allergic Rhinitis: A Randomized Controlled Trial

Jung JW, Kang HR, Kim MH, et al.

Allergy, Asthma & Immunology Research (2023)

57% Nasal symptom reduction
94 patients Study population
4 weeks Treatment duration

Socheongryong-tang demonstrates symptom relief efficacy comparable to antihistamines for allergic rhinitis with fewer side effects, serving as a safe alternative treatment option.

View Source 2023
RCT ENT Disorders

Therapeutic Effect of Socheongryong-tang on Allergic Rhinitis: A Randomized Controlled Trial

Jung JW, Kang HR, Kim MH, et al. Allergy, Asthma & Immunology Research (2023)
57% Nasal symptom reduction
94 patients Study population
4 weeks Treatment duration

Summary

A randomized controlled trial comparing 4 weeks of Socheongryong-tang versus cetirizine alone in 94 patients with seasonal allergic rhinitis. The Socheongryong-tang group showed a 57% reduction in Total Nasal Symptom Score (TNSS), comparable to cetirizine (51%), while having significantly fewer side effects including drowsiness.

Key Conclusion

Socheongryong-tang demonstrates symptom relief efficacy comparable to antihistamines for allergic rhinitis with fewer side effects, serving as a safe alternative treatment option.

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