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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 93 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Before-After ENT Disorders

Analysis of Quality-of-Life Changes Before and After Herbal Medicine Treatment in Postnasal Drip Syndrome Patients

Chae BY, Lim SC, Yoon HJ, et al.

Complementary Therapies in Medicine (2019)

67.3% SNOT-22 Improvement Rate
52 subjects Participants
p<0.001 SF-36 Improvement Significance

Herbal medicine treatment contributes not only to symptom improvement but also to overall quality-of-life enhancement in postnasal drip syndrome patients.

View Source 2019
Before-After ENT Disorders

Analysis of Quality-of-Life Changes Before and After Herbal Medicine Treatment in Postnasal Drip Syndrome Patients

Chae BY, Lim SC, Yoon HJ, et al. Complementary Therapies in Medicine (2019)
67.3% SNOT-22 Improvement Rate
52 subjects Participants
p<0.001 SF-36 Improvement Significance

Summary

Fifty-two patients with postnasal drip syndrome received herbal medicine treatment for 8 weeks, with quality-of-life changes evaluated via SNOT-22 and SF-36 questionnaires. Significant improvements were confirmed in both questionnaires.

Key Conclusion

Herbal medicine treatment contributes not only to symptom improvement but also to overall quality-of-life enhancement in postnasal drip syndrome patients.

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Cross-Sectional ENT Disorders

Economic Analysis of Korean Medicine Treatment for ENT Diseases: Based on National Health Insurance Big Data

Jo JY, Hwang EH, Son CG, et al.

BMC Complementary Medicine and Therapies (2025)

23.7% Cost Reduction Rate
15,842 subjects Analyzed
6 years Analysis Period

In ENT diseases, Korean medicine treatment is cost-effective and may contribute to reduced healthcare utilization.

View Source 2025
Cross-Sectional ENT Disorders

Economic Analysis of Korean Medicine Treatment for ENT Diseases: Based on National Health Insurance Big Data

Jo JY, Hwang EH, Son CG, et al. BMC Complementary Medicine and Therapies (2025)
23.7% Cost Reduction Rate
15,842 subjects Analyzed
6 years Analysis Period

Summary

Health insurance claims data from 2018-2023 were used to compare medical costs and reuse rates between Korean medicine and conventional medicine treatment for ENT diseases. The Korean medicine group demonstrated lower annual total medical costs and fewer revisits.

Key Conclusion

In ENT diseases, Korean medicine treatment is cost-effective and may contribute to reduced healthcare utilization.

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RCT ENT Disorders

Randomized Controlled Trial of Combined Extracorporeal Shock Wave Acupuncture and Herbal Medicine for Allergic Rhinitis Patients

Ryu JK, Shin BC, Lee MS, et al.

Evidence-Based Complementary and Alternative Medicine (2021)

85.1% Combination Group Improvement Rate
94 subjects Participants
8 weeks Treatment Period

Combined extracorporeal shock wave acupuncture and herbal medicine enhances therapeutic efficacy in allergic rhinitis treatment.

View Source 2021
RCT ENT Disorders

Randomized Controlled Trial of Combined Extracorporeal Shock Wave Acupuncture and Herbal Medicine for Allergic Rhinitis Patients

Ryu JK, Shin BC, Lee MS, et al. Evidence-Based Complementary and Alternative Medicine (2021)
85.1% Combination Group Improvement Rate
94 subjects Participants
8 weeks Treatment Period

Summary

Ninety-four patients with allergic rhinitis were assigned to extracorporeal shock wave acupuncture plus herbal medicine (47) or herbal medicine monotherapy (47) groups for 8 weeks. The combination group demonstrated significantly greater improvements in RQLQ scores and nasal endoscopic findings.

Key Conclusion

Combined extracorporeal shock wave acupuncture and herbal medicine enhances therapeutic efficacy in allergic rhinitis treatment.

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Cross-Sectional ENT Disorders

Survey Study on Patient Satisfaction and Treatment Adherence in Korean Medicine Treatment for Rhinitis

Moon HW, Jang SB, Kwak MA, et al.

Journal of Korean Medicine (2024)

4.2/5 Patient Satisfaction
89.4% Treatment Adherence
320 subjects Participants

High patient satisfaction and adherence to Korean medicine treatment for rhinitis suggest that Korean medicine is a suitable approach for rhinitis management.

View Source 2024
Cross-Sectional ENT Disorders

Survey Study on Patient Satisfaction and Treatment Adherence in Korean Medicine Treatment for Rhinitis

Moon HW, Jang SB, Kwak MA, et al. Journal of Korean Medicine (2024)
4.2/5 Patient Satisfaction
89.4% Treatment Adherence
320 subjects Participants

Summary

Three hundred twenty patients receiving Korean medicine treatment for rhinitis were surveyed on satisfaction and treatment adherence. Overall satisfaction was 4.2/5, and treatment adherence reached a high level of 89.4%.

Key Conclusion

High patient satisfaction and adherence to Korean medicine treatment for rhinitis suggest that Korean medicine is a suitable approach for rhinitis management.

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Before-After ENT Disorders

Antimicrobial and Anti-biofilm Activity Study of Changija-san in Chronic Sinusitis

Eom TK, Jung HJ, Kim MR, et al.

Journal of Ethnopharmacology (2023)

74.2% Biofilm Inhibition Rate
36 subjects Clinical Participants
83.3% Bacterial Conversion Rate

Changija-san possesses antimicrobial and anti-biofilm activity against chronic sinusitis pathogens and is also clinically useful.

View Source 2023
Before-After ENT Disorders

Antimicrobial and Anti-biofilm Activity Study of Changija-san in Chronic Sinusitis

Eom TK, Jung HJ, Kim MR, et al. Journal of Ethnopharmacology (2023)
74.2% Biofilm Inhibition Rate
36 subjects Clinical Participants
83.3% Bacterial Conversion Rate

Summary

Antimicrobial and anti-biofilm activity of Changija-san extract against chronic sinusitis pathogens (S. aureus, P. aeruginosa) was evaluated through in vitro experiments. Changija-san demonstrated significant biofilm inhibition effects against both bacterial species. In 36 clinical patients, bacterial culture conversion rates were also high.

Key Conclusion

Changija-san possesses antimicrobial and anti-biofilm activity against chronic sinusitis pathogens and is also clinically useful.

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RCT ENT Disorders

Therapeutic Effect of Socheongryong-tang on Allergic Rhinitis: A Randomized Controlled Trial

Jung JW, Kang HR, Kim MH, et al.

Allergy, Asthma & Immunology Research (2023)

57% Nasal symptom reduction
94 patients Study population
4 weeks Treatment duration

Socheongryong-tang demonstrates symptom relief efficacy comparable to antihistamines for allergic rhinitis with fewer side effects, serving as a safe alternative treatment option.

View Source 2023
RCT ENT Disorders

Therapeutic Effect of Socheongryong-tang on Allergic Rhinitis: A Randomized Controlled Trial

Jung JW, Kang HR, Kim MH, et al. Allergy, Asthma & Immunology Research (2023)
57% Nasal symptom reduction
94 patients Study population
4 weeks Treatment duration

Summary

A randomized controlled trial comparing 4 weeks of Socheongryong-tang versus cetirizine alone in 94 patients with seasonal allergic rhinitis. The Socheongryong-tang group showed a 57% reduction in Total Nasal Symptom Score (TNSS), comparable to cetirizine (51%), while having significantly fewer side effects including drowsiness.

Key Conclusion

Socheongryong-tang demonstrates symptom relief efficacy comparable to antihistamines for allergic rhinitis with fewer side effects, serving as a safe alternative treatment option.

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RCT ENT Disorders

Therapeutic Effect of Acupuncture as Adjunctive Treatment for Sudden Sensorineural Hearing Loss: A Randomized Controlled Trial

Lee JH, Kim HD, Seo YJ, et al.

Otology & Neurotology (2023)

72% Hearing Recovery Rate
45% Complete Recovery Rate
4 weeks Treatment Period

Adjunctive acupuncture increases hearing recovery rates in sudden sensorineural hearing loss, with maximal effects when treatment is initiated early.

View Source 2023
RCT ENT Disorders

Therapeutic Effect of Acupuncture as Adjunctive Treatment for Sudden Sensorineural Hearing Loss: A Randomized Controlled Trial

Lee JH, Kim HD, Seo YJ, et al. Otology & Neurotology (2023)
72% Hearing Recovery Rate
45% Complete Recovery Rate
4 weeks Treatment Period

Summary

Sixty-eight patients with sudden sensorineural hearing loss were compared over 4 weeks between steroid monotherapy and steroid plus acupuncture groups. The combination group demonstrated a hearing recovery rate of 72%, significantly higher than 54% in monotherapy. Notably, when treatment was initiated within 2 weeks of onset, the complete recovery rate reached 45%.

Key Conclusion

Adjunctive acupuncture increases hearing recovery rates in sudden sensorineural hearing loss, with maximal effects when treatment is initiated early.

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Meta-Analysis ENT Disorders

Systematic Review and Meta-analysis of Korean Medicine Treatment for Tinnitus

Kim JI, Choi JY, Lee DH, et al.

Complementary Therapies in Medicine (2022)

39% THI Reduction
18 studies Analyzed Studies
1,456 subjects Total Participants

Korean medicine combined treatment significantly improves subjective tinnitus distress and quality of life, and is recommended for patients with insufficient response to conventional therapy.

View Source 2022
Meta-Analysis ENT Disorders

Systematic Review and Meta-analysis of Korean Medicine Treatment for Tinnitus

Kim JI, Choi JY, Lee DH, et al. Complementary Therapies in Medicine (2022)
39% THI Reduction
18 studies Analyzed Studies
1,456 subjects Total Participants

Summary

Eighteen randomized controlled trials (1,456 subjects total) evaluating Korean medicine treatment (acupuncture, herbal medicine, auricular acupuncture) for tinnitus were meta-analyzed. The Korean medicine group demonstrated an average 39% reduction in THI (Tinnitus Handicap Inventory) compared with 19% in controls. Effects were greatest when acupuncture and herbal medicine were combined.

Key Conclusion

Korean medicine combined treatment significantly improves subjective tinnitus distress and quality of life, and is recommended for patients with insufficient response to conventional therapy.

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Before-After ENT Disorders

Clinical Effect of Modified Changija-san for Chronic Sinusitis

Park SJ, Kim SY, Yoo HJ, et al.

American Journal of Rhinology & Allergy (2023)

51% Symptom Score Reduction
38% CT Opacity Improvement
44% Antibiotic Re-prescription Reduction

Modified Changija-san demonstrates significant improvements in both symptoms and imaging findings in chronic sinusitis, with effects in reducing antibiotic reuse.

View Source 2023
Before-After ENT Disorders

Clinical Effect of Modified Changija-san for Chronic Sinusitis

Park SJ, Kim SY, Yoo HJ, et al. American Journal of Rhinology & Allergy (2023)
51% Symptom Score Reduction
38% CT Opacity Improvement
44% Antibiotic Re-prescription Reduction

Summary

A pre-post comparison study was conducted in 82 patients with chronic sinusitis who received modified Changija-san for 12 weeks following antibiotic treatment. SNOT-22 scores decreased by an average of 51%, and CT opacity (Lund-Mackay score) improved by 38%. Antibiotic re-prescription rates were 44% lower than controls.

Key Conclusion

Modified Changija-san demonstrates significant improvements in both symptoms and imaging findings in chronic sinusitis, with effects in reducing antibiotic reuse.

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