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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Total 93 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Meta-Analysis ENT Disorders

Comparative Effectiveness Analysis of Korean Medicine and Conventional Medicine for Rhinitis: A Meta-analysis

Son MJ, Lim CE, Park SK, et al.

Evidence-Based Complementary and Alternative Medicine (2024)

Non-inferior Korean vs. Conventional
2156 subjects Total Participants
22 papers Analyzed Papers

Korean medicine treatment shows non-inferior efficacy compared to conventional medicine treatment with fewer side effects, and can be considered as an alternative treatment.

View Source 2024
Meta-Analysis ENT Disorders

Comparative Effectiveness Analysis of Korean Medicine and Conventional Medicine for Rhinitis: A Meta-analysis

Son MJ, Lim CE, Park SK, et al. Evidence-Based Complementary and Alternative Medicine (2024)
Non-inferior Korean vs. Conventional
2156 subjects Total Participants
22 papers Analyzed Papers

Summary

Twenty-two RCTs (2,156 subjects total) comparing Korean medicine treatment (herbal medicine, acupuncture) and conventional medicine treatment (antihistamines, intranasal steroids) for rhinitis were meta-analyzed. There was no significant difference in symptom improvement rates between Korean medicine and conventional medicine groups.

Key Conclusion

Korean medicine treatment shows non-inferior efficacy compared to conventional medicine treatment with fewer side effects, and can be considered as an alternative treatment.

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Before-After ENT Disorders

Antimicrobial and Anti-inflammatory Effects of Modified Gamgil-tang for Chronic Tonsillitis

Woo JH, Yoo HR, Kim JH, et al.

Journal of Ethnopharmacology (2022)

68.4% Tonsil Size Reduction Rate
78 subjects Participants
p<0.01 CRP Reduction Significance

Modified Gamgil-tang is an effective prescription for inflammation suppression and tonsil size reduction in chronic tonsillitis.

View Source 2022
Before-After ENT Disorders

Antimicrobial and Anti-inflammatory Effects of Modified Gamgil-tang for Chronic Tonsillitis

Woo JH, Yoo HR, Kim JH, et al. Journal of Ethnopharmacology (2022)
68.4% Tonsil Size Reduction Rate
78 subjects Participants
p<0.01 CRP Reduction Significance

Summary

Seventy-eight patients with chronic tonsillitis were evaluated for the effects of modified Gamgil-tang. Inflammatory markers including CRP and ESR significantly decreased, and tonsil size also reduced.

Key Conclusion

Modified Gamgil-tang is an effective prescription for inflammation suppression and tonsil size reduction in chronic tonsillitis.

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Systematic Review ENT Disorders

Efficacy and Safety of Bee Venom Pharmacopuncture in Allergic Rhinitis Patients: A Systematic Review

Lim JA, Kim KW, Song MY, et al.

BMC Complementary Medicine and Therapies (2023)

73.8% Symptom Improvement Rate
634 subjects Total Participants
9 papers Analyzed Papers

Bee venom pharmacopuncture demonstrated efficacy and safety as a complementary method for allergic rhinitis treatment.

View Source 2023
Systematic Review ENT Disorders

Efficacy and Safety of Bee Venom Pharmacopuncture in Allergic Rhinitis Patients: A Systematic Review

Lim JA, Kim KW, Song MY, et al. BMC Complementary Medicine and Therapies (2023)
73.8% Symptom Improvement Rate
634 subjects Total Participants
9 papers Analyzed Papers

Summary

Nine clinical trials (634 subjects total) were systematically analyzed to evaluate the efficacy of bee venom pharmacopuncture for allergic rhinitis. Significant improvements in nasal obstruction, watery rhinorrhea, and sneezing scores were observed in the bee venom group.

Key Conclusion

Bee venom pharmacopuncture demonstrated efficacy and safety as a complementary method for allergic rhinitis treatment.

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RCT ENT Disorders

Randomized Controlled Trial of Banhahubak-tang for Patients with Chronic Cough Accompanied by Postnasal Drip

Jung IC, Lee SR, Kim AR, et al.

Phytomedicine (2024)

72.7% Cough Reduction Rate
88 subjects Participants
6 weeks Treatment Period

Banhahubak-tang is an effective treatment option for chronic cough accompanied by postnasal drip.

View Source 2024
RCT ENT Disorders

Randomized Controlled Trial of Banhahubak-tang for Patients with Chronic Cough Accompanied by Postnasal Drip

Jung IC, Lee SR, Kim AR, et al. Phytomedicine (2024)
72.7% Cough Reduction Rate
88 subjects Participants
6 weeks Treatment Period

Summary

Eighty-eight patients with chronic cough accompanied by postnasal drip were divided into Banhahubak-tang treatment (44) and placebo (44) groups for 6 weeks of treatment. Cough frequency and postnasal drip symptoms decreased significantly in the treatment group.

Key Conclusion

Banhahubak-tang is an effective treatment option for chronic cough accompanied by postnasal drip.

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Narrative Review ENT Disorders

Narrative Review of Moxibustion Effects in ENT Diseases

Cho SY, Park JM, Kwak HY, et al.

Journal of Korean Medicine (2021)

62 papers Analyzed Papers
3 categories Major Disease Groups
Moderate Evidence Level

Moxibustion can be utilized as a complementary treatment in ENT diseases, but more high-quality RCTs are needed.

View Source 2021
Narrative Review ENT Disorders

Narrative Review of Moxibustion Effects in ENT Diseases

Cho SY, Park JM, Kwak HY, et al. Journal of Korean Medicine (2021)
62 papers Analyzed Papers
3 categories Major Disease Groups
Moderate Evidence Level

Summary

Sixty-two articles related to moxibustion in ENT diseases (rhinitis, otitis media, tonsillitis, etc.) were analyzed to summarize treatment mechanisms and effects. Moxibustion was reported to exert effects through local blood flow improvement and immunomodulation.

Key Conclusion

Moxibustion can be utilized as a complementary treatment in ENT diseases, but more high-quality RCTs are needed.

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Cohort Study ENT Disorders

Analysis of Gut Microbiota Changes Following Herbal Medicine Treatment in Rhinitis Patients: A Cohort Study

Min WK, Song JH, Yun YJ, et al.

Journal of Ethnopharmacology (2025)

42.3% Beneficial Bacteria Increase
60 subjects Participants
12 weeks Follow-up Period

Herbal medicine treatment improves gut microbiota diversity in rhinitis patients, which may be related to immunomodulation.

View Source 2025
Cohort Study ENT Disorders

Analysis of Gut Microbiota Changes Following Herbal Medicine Treatment in Rhinitis Patients: A Cohort Study

Min WK, Song JH, Yun YJ, et al. Journal of Ethnopharmacology (2025)
42.3% Beneficial Bacteria Increase
60 subjects Participants
12 weeks Follow-up Period

Summary

Sixty allergic rhinitis patients received herbal medicine treatment for 12 weeks, with gut microbiota changes tracked via 16S rRNA analysis. Lactobacillus and Bifidobacterium proportions significantly increased after treatment.

Key Conclusion

Herbal medicine treatment improves gut microbiota diversity in rhinitis patients, which may be related to immunomodulation.

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RCT ENT Disorders

Randomized Controlled Trial of Korean Medicine Treatment for Recurrence Prevention After Sinus Surgery

Kang WC, Lee DH, Chung YJ, et al.

Complementary Therapies in Medicine (2022)

18.2% Herbal Group Recurrence Rate
38.1% Control Group Recurrence Rate
110 subjects Participants

Combined herbal medicine treatment after sinus surgery is effective in preventing sinusitis recurrence.

View Source 2022
RCT ENT Disorders

Randomized Controlled Trial of Korean Medicine Treatment for Recurrence Prevention After Sinus Surgery

Kang WC, Lee DH, Chung YJ, et al. Complementary Therapies in Medicine (2022)
18.2% Herbal Group Recurrence Rate
38.1% Control Group Recurrence Rate
110 subjects Participants

Summary

One hundred ten patients after endoscopic sinus surgery were compared over 12 months between herbal medicine combined treatment (55) and standard post-surgical care (55) groups for recurrence prevention. The herbal medicine combination group showed significantly lower recurrence rates.

Key Conclusion

Combined herbal medicine treatment after sinus surgery is effective in preventing sinusitis recurrence.

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Meta-Analysis ENT Disorders

Meta-analysis of Korean Medicine Treatment for Pediatric Otitis Media with Effusion

Seo JC, Park SU, Cho CS, et al.

Evidence-Based Complementary and Alternative Medicine (2020)

69.7% Effusion Resolution Rate
1078 subjects Total Participants
14 papers Analyzed Papers

Korean medicine treatment is an effective therapy for non-surgical management of pediatric otitis media with effusion.

View Source 2020
Meta-Analysis ENT Disorders

Meta-analysis of Korean Medicine Treatment for Pediatric Otitis Media with Effusion

Seo JC, Park SU, Cho CS, et al. Evidence-Based Complementary and Alternative Medicine (2020)
69.7% Effusion Resolution Rate
1078 subjects Total Participants
14 papers Analyzed Papers

Summary

Fourteen clinical trials (1,078 subjects total) were meta-analyzed to evaluate the effects of Korean medicine treatment (herbal medicine, acupuncture) for pediatric otitis media with effusion. The Korean medicine group demonstrated significantly higher effusion resolution rates compared with controls.

Key Conclusion

Korean medicine treatment is an effective therapy for non-surgical management of pediatric otitis media with effusion.

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Cross-Sectional ENT Disorders

Analysis of Differential Treatment Response by Sasang Constitution in Allergic Rhinitis Herbal Medicine Treatment: A Cross-Sectional Study

Yoo JE, Kim DH, Choi JB, et al.

BMC Complementary Medicine and Therapies (2024)

200 subjects Participants
86.4% Taeumin Improvement Rate
83.7% Soyangin Improvement Rate

Customized herbal prescription based on Sasang constitution can enhance the therapeutic efficacy of allergic rhinitis treatment.

View Source 2024
Cross-Sectional ENT Disorders

Analysis of Differential Treatment Response by Sasang Constitution in Allergic Rhinitis Herbal Medicine Treatment: A Cross-Sectional Study

Yoo JE, Kim DH, Choi JB, et al. BMC Complementary Medicine and Therapies (2024)
200 subjects Participants
86.4% Taeumin Improvement Rate
83.7% Soyangin Improvement Rate

Summary

Two hundred patients receiving herbal medicine treatment for allergic rhinitis were classified by Sasang constitution and analyzed for treatment response. Soyangin and Taeumin showed the highest treatment efficacy, with constitution-tailored prescriptions affecting outcomes.

Key Conclusion

Customized herbal prescription based on Sasang constitution can enhance the therapeutic efficacy of allergic rhinitis treatment.

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Cohort Study ENT Disorders

Prospective Cohort Study of Acupotomy for Chronic Hypertrophic Rhinitis

Heo DS, Nam SS, Ahn YC, et al.

Journal of Ethnopharmacology (2021)

61.5% Nasal Resistance Reduction
72 subjects Participants
6 months Follow-up Period

Acupotomy is effective in improving nasal airflow in chronic hypertrophic rhinitis.

View Source 2021
Cohort Study ENT Disorders

Prospective Cohort Study of Acupotomy for Chronic Hypertrophic Rhinitis

Heo DS, Nam SS, Ahn YC, et al. Journal of Ethnopharmacology (2021)
61.5% Nasal Resistance Reduction
72 subjects Participants
6 months Follow-up Period

Summary

Seventy-two patients with chronic hypertrophic rhinitis received 4 sessions of acupotomy and were followed for 6 months. Nasal resistance significantly decreased on rhinomanometry, and subjective nasal congestion scores also improved.

Key Conclusion

Acupotomy is effective in improving nasal airflow in chronic hypertrophic rhinitis.

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Case Study ENT Disorders

Antipyretic and Anti-inflammatory Effect of Eungyo-san for Acute Tonsillitis: A Case Report

Go HY, Kim SJ, Baik TH, et al.

Journal of Korean Medicine (2023)

70% Pharyngeal Pain Reduction
15 subjects Participants
48 hours Time to Defervescence

Eungyo-san is an effective herbal prescription for rapid symptom relief in acute tonsillitis.

View Source 2023
Case Study ENT Disorders

Antipyretic and Anti-inflammatory Effect of Eungyo-san for Acute Tonsillitis: A Case Report

Go HY, Kim SJ, Baik TH, et al. Journal of Korean Medicine (2023)
70% Pharyngeal Pain Reduction
15 subjects Participants
48 hours Time to Defervescence

Summary

Fifteen adult patients visiting clinic for acute tonsillitis received Eungyo-san with progress monitoring for 7 days. Fever resolved within 48 hours of administration, and pharyngeal pain VAS scores decreased by an average of 70%.

Key Conclusion

Eungyo-san is an effective herbal prescription for rapid symptom relief in acute tonsillitis.

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Systematic Review ENT Disorders

Combined Effect of Nasal Irrigation and Herbal Medicine for Rhinitis Treatment: A Systematic Review

Noh JH, Kim KS, Won JY, et al.

Phytomedicine (2022)

88.1% Combination Group Efficacy
10 papers Analyzed Papers
OR 2.34 Effect Size

Combination of nasal irrigation and herbal medicine demonstrates synergistic effects in rhinitis treatment.

View Source 2022
Systematic Review ENT Disorders

Combined Effect of Nasal Irrigation and Herbal Medicine for Rhinitis Treatment: A Systematic Review

Noh JH, Kim KS, Won JY, et al. Phytomedicine (2022)
88.1% Combination Group Efficacy
10 papers Analyzed Papers
OR 2.34 Effect Size

Summary

Ten RCTs were analyzed to evaluate the combined effect of nasal irrigation and herbal medicine for rhinitis treatment. The combination group demonstrated superior symptom improvement compared with herbal medicine alone or nasal irrigation alone.

Key Conclusion

Combination of nasal irrigation and herbal medicine demonstrates synergistic effects in rhinitis treatment.

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