금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
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Total 93 papers

RCT ENT Disorders

Therapeutic Effect of Modified Okbyeongpung-san for Allergic Rhinitis: A Multicenter Randomized Controlled Trial

Kim HJ, Cho JH, Nam DH, et al.

Allergy, Asthma & Immunology Research (2024)

58% TNSS Reduction Rate
156 subjects Participants
p=0.042 Recurrence Significance

Modified Okbyeongpung-san demonstrates equivalent efficacy to conventional medication in allergic rhinitis symptom control and is superior in long-term recurrence prevention.

RCT ENT Disorders

Therapeutic Effect of Modified Okbyeongpung-san for Allergic Rhinitis: A Multicenter Randomized Controlled Trial

Kim HJ, Cho JH, Nam DH, et al. Allergy, Asthma & Immunology Research (2024)
58% TNSS Reduction Rate
156 subjects Participants
p=0.042 Recurrence Significance

Summary

One hundred fifty-six patients with perennial allergic rhinitis were randomized to modified Okbyeongpung-san or loratadine groups for 8 weeks of treatment. The herbal group's TNSS (Total Nasal Symptom Score) reduction rate was 58%, non-inferior to loratadine (49%), with significantly lower recurrence rates 4 weeks after treatment completion.

Key Conclusion

Modified Okbyeongpung-san demonstrates equivalent efficacy to conventional medication in allergic rhinitis symptom control and is superior in long-term recurrence prevention.

Before-After ENT Disorders

Nasal Airway Patency Improvement Effect of Moxibustion for Allergic Rhinitis Patients with Nasal Obstruction as Chief Complaint

정현석, 박미래, 김우진, et al.

Moxibustion Research (2024)

38% Nasal resistance reduction
68 patients Study population
8 weeks Treatment duration

Moxibustion objectively improves nasal airway patency in allergic rhinitis patients and has high utility as a non-pharmacological adjunctive treatment.

Before-After ENT Disorders

Nasal Airway Patency Improvement Effect of Moxibustion for Allergic Rhinitis Patients with Nasal Obstruction as Chief Complaint

정현석, 박미래, 김우진, et al. Moxibustion Research (2024)
38% Nasal resistance reduction
68 patients Study population
8 weeks Treatment duration

Summary

A pre-post comparison study performing indirect moxibustion for 8 weeks at ST36 and LI4 in 68 allergic rhinitis patients with chief complaint of nasal obstruction. Total nasal airway resistance on rhinomanometry decreased by 38% compared to before treatment, with significantly improved subjective nasal obstruction VAS.

Key Conclusion

Moxibustion objectively improves nasal airway patency in allergic rhinitis patients and has high utility as a non-pharmacological adjunctive treatment.

RCT ENT Disorders

Anti-Inflammatory Effect of Hyeonggaeyeongyo-tang for Acute Sinusitis: A Randomized Controlled Trial

김태완, 이서연, 박준혁, et al.

Evidence-Based Complementary and Alternative Medicine (2024)

78% Symptom improvement rate
92 patients Study population
2 weeks Treatment duration

Hyeonggaeyeongyo-tang shows efficacy equivalent to antibiotics for anti-inflammatory treatment of acute sinusitis and can be safely used without resistance concerns.

RCT ENT Disorders

Anti-Inflammatory Effect of Hyeonggaeyeongyo-tang for Acute Sinusitis: A Randomized Controlled Trial

김태완, 이서연, 박준혁, et al. Evidence-Based Complementary and Alternative Medicine (2024)
78% Symptom improvement rate
92 patients Study population
2 weeks Treatment duration

Summary

A randomized controlled trial comparing Hyeonggaeyeongyo-tang treatment versus antibiotic alone groups in 92 patients with acute sinusitis. After 2 weeks of treatment, the Hyeonggaeyeongyo-tang group showed significant improvements in sinus tenderness and purulent rhinorrhea, with decreased sinus opacity scores on CT.

Key Conclusion

Hyeonggaeyeongyo-tang shows efficacy equivalent to antibiotics for anti-inflammatory treatment of acute sinusitis and can be safely used without resistance concerns.

Cross-Sectional ENT Disorders

Effect of Combined Acupuncture and Moxibustion for Eustachian Tube Dysfunction: A Cross-Sectional Study

Lee YK, Song JH, Park KM, et al.

Acupuncture in Medicine (2023)

44% ETDQ-7 Improvement Rate
57% Eustachian Function Normalization
76 subjects Participants

Combined acupuncture and moxibustion is an effective treatment method for symptom improvement and Eustachian tube function recovery in Eustachian tube dysfunction.

Cross-Sectional ENT Disorders

Effect of Combined Acupuncture and Moxibustion for Eustachian Tube Dysfunction: A Cross-Sectional Study

Lee YK, Song JH, Park KM, et al. Acupuncture in Medicine (2023)
44% ETDQ-7 Improvement Rate
57% Eustachian Function Normalization
76 subjects Participants

Summary

Seventy-six patients with Eustachian tube dysfunction received combined acupuncture (Xiaguan, Ermen, Tinggong) and mastoid moxibustion, with ETDQ-7 questionnaire and tympanometry assessment. ETDQ-7 scores improved by an average of 44% after treatment, with a 57% Eustachian tube opening function normalization rate.

Key Conclusion

Combined acupuncture and moxibustion is an effective treatment method for symptom improvement and Eustachian tube function recovery in Eustachian tube dysfunction.

Narrative Review ENT Disorders

Korean Medicine Treatment Experience for Tinnitus as a Sequela of Chronic Otitis Media: A Narrative Review

Baek SH, Oh MS, Kwon OS, et al.

Journal of Traditional Chinese Medicine (2024)

22 papers Reviewed Papers
78% Average Efficacy Rate
3 methods Major Treatments

Korean medicine treatment for tinnitus after chronic otitis media has diverse evidence, but large-scale clinical trials are needed in the future.

Narrative Review ENT Disorders

Korean Medicine Treatment Experience for Tinnitus as a Sequela of Chronic Otitis Media: A Narrative Review

Baek SH, Oh MS, Kwon OS, et al. Journal of Traditional Chinese Medicine (2024)
22 papers Reviewed Papers
78% Average Efficacy Rate
3 methods Major Treatments

Summary

Twenty-two articles on Korean medicine treatment (acupuncture, herbal medicine, auricular acupuncture) for persistent tinnitus after chronic otitis media were narratively reviewed. In most studies, acupuncture utilizing peri-aural acupoints (Ermen, Tinggong, Tinghui) and herbal medicines such as Ironggojadan-tang were effective for tinnitus alleviation.

Key Conclusion

Korean medicine treatment for tinnitus after chronic otitis media has diverse evidence, but large-scale clinical trials are needed in the future.

Before-After ENT Disorders

Therapeutic Effect of Socheongryong-tang for Chronic Otitis Media with Effusion in Pediatric Patients: A Pre-Post Comparison Study

Jung WS, Kim MJ, Yoo JH, et al.

International Journal of Pediatric Otorhinolaryngology (2023)

64% Tympanic Normalization Rate
15 dB Hearing Improvement
45 subjects Participants

Socheongryong-tang is an effective herbal treatment that promotes effusion absorption and hearing recovery in pediatric otitis media with effusion.

Before-After ENT Disorders

Therapeutic Effect of Socheongryong-tang for Chronic Otitis Media with Effusion in Pediatric Patients: A Pre-Post Comparison Study

Jung WS, Kim MJ, Yoo JH, et al. International Journal of Pediatric Otorhinolaryngology (2023)
64% Tympanic Normalization Rate
15 dB Hearing Improvement
45 subjects Participants

Summary

Forty-five pediatric patients diagnosed with otitis media with effusion received Socheongryong-tang for 8 weeks, resulting in a 64% normalization rate (Type B to Type A) on tympanometry. Hearing improvement averaged 15 dB.

Key Conclusion

Socheongryong-tang is an effective herbal treatment that promotes effusion absorption and hearing recovery in pediatric otitis media with effusion.

RCT ENT Disorders

Therapeutic Effect of Modified Banhabaekchulcheonma-tang for Meniere's Disease: A Multicenter Randomized Controlled Trial

Yoon SJ, Lee KH, Hwang DS, et al.

European Archives of Oto-Rhino-Laryngology (2024)

68% Attack Frequency Reduction
112 subjects Participants
8 weeks Treatment Period

Modified Banhabaekchulcheonma-tang demonstrates superior efficacy to betahistine in vertigo attack control and hearing stabilization in Meniere's disease.

RCT ENT Disorders

Therapeutic Effect of Modified Banhabaekchulcheonma-tang for Meniere's Disease: A Multicenter Randomized Controlled Trial

Yoon SJ, Lee KH, Hwang DS, et al. European Archives of Oto-Rhino-Laryngology (2024)
68% Attack Frequency Reduction
112 subjects Participants
8 weeks Treatment Period

Summary

One hundred twelve patients with Meniere's disease were compared over 8 weeks between modified Banhabaekchulcheonma-tang and betahistine groups. The herbal group demonstrated a 68% reduction in vertigo attack frequency, significantly superior to the betahistine group (52%). Hearing fluctuation amplitude was also more stable in the herbal group.

Key Conclusion

Modified Banhabaekchulcheonma-tang demonstrates superior efficacy to betahistine in vertigo attack control and hearing stabilization in Meniere's disease.

Systematic Review ENT Disorders

Effect of Korean Medicine Combined Treatment on Cognitive Decline in Presbycusis Patients: A Systematic Review

Choi YS, Park JH, Kim EJ, et al.

Journal of Aging and Health (2023)

14 studies Analyzed Studies
2.8 points MMSE Improvement
p<0.01 Statistical Significance

Korean medicine combined treatment has the potential to simultaneously improve hearing and cognitive function in presbycusis patients.

Systematic Review ENT Disorders

Effect of Korean Medicine Combined Treatment on Cognitive Decline in Presbycusis Patients: A Systematic Review

Choi YS, Park JH, Kim EJ, et al. Journal of Aging and Health (2023)
14 studies Analyzed Studies
2.8 points MMSE Improvement
p<0.01 Statistical Significance

Summary

Fourteen studies on Korean medicine intervention for the association between presbycusis and cognitive decline were systematically reviewed. The combined acupuncture and herbal medicine group demonstrated an average 2.8-point improvement in MMSE scores, with positive correlation confirmed between hearing improvement and cognitive function improvement.

Key Conclusion

Korean medicine combined treatment has the potential to simultaneously improve hearing and cognitive function in presbycusis patients.

RCT ENT Disorders

Synergistic Effect of Combined Acupuncture and Hearing Aid Use for Sensorineural Hearing Loss: A Randomized Controlled Trial

Lee DH, Seo JW, Han KS, et al.

Audiology and Speech Research (2023)

18% Additional SRS Improvement
86 subjects Participants
12 weeks Follow-up Period

Adjunctive acupuncture enhances hearing aid rehabilitation effects in sensorineural hearing loss patients and contributes to improved speech recognition ability.

RCT ENT Disorders

Synergistic Effect of Combined Acupuncture and Hearing Aid Use for Sensorineural Hearing Loss: A Randomized Controlled Trial

Lee DH, Seo JW, Han KS, et al. Audiology and Speech Research (2023)
18% Additional SRS Improvement
86 subjects Participants
12 weeks Follow-up Period

Summary

Eighty-six patients with sensorineural hearing loss were randomized to hearing aid monotherapy or hearing aid plus acupuncture combination groups and followed for 12 weeks. The combination group demonstrated an average 18% greater improvement in speech recognition score (SRS), with significantly higher hearing aid adaptation satisfaction.

Key Conclusion

Adjunctive acupuncture enhances hearing aid rehabilitation effects in sensorineural hearing loss patients and contributes to improved speech recognition ability.

Cohort Study ENT Disorders

Effect of Auricular Acupuncture on Tinnitus Patients: A Prospective Cohort Study

Park SH, Kim YJ, Choi MK, et al.

Journal of Korean Medicine Otolaryngology (2024)

41% THI Reduction Rate
124 subjects Participants
8 weeks Treatment Period

Auricular acupuncture is an effective non-invasive treatment for symptom alleviation and sleep quality improvement in tinnitus patients.

Cohort Study ENT Disorders

Effect of Auricular Acupuncture on Tinnitus Patients: A Prospective Cohort Study

Park SH, Kim YJ, Choi MK, et al. Journal of Korean Medicine Otolaryngology (2024)
41% THI Reduction Rate
124 subjects Participants
8 weeks Treatment Period

Summary

One hundred twenty-four patients with tinnitus received auricular acupuncture for 8 weeks, with THI and VAS changes tracked. The auricular acupuncture group demonstrated an average 41% reduction in THI scores, with significant improvement in sleep quality (PSQI). Stimulation at the Shenmen and Inner Ear acupoints was particularly effective.

Key Conclusion

Auricular acupuncture is an effective non-invasive treatment for symptom alleviation and sleep quality improvement in tinnitus patients.

Narrative Review ENT Disorders

Narrative Review of Acupuncture Effects for Nasal Obstruction Related to Deviated Nasal Septum

정해인, 이광수, 김나연, et al.

Korean Journal of Acupuncture (2023)

8 studies Reviewed papers
6 acupoints Major acupoints used
73% Mean symptom improvement rate

Acupuncture can be utilized as a conservative treatment for nasal obstruction symptoms in patients with deviated nasal septum, and well-designed clinical trials are needed in the future.

Narrative Review ENT Disorders

Narrative Review of Acupuncture Effects for Nasal Obstruction Related to Deviated Nasal Septum

정해인, 이광수, 김나연, et al. Korean Journal of Acupuncture (2023)
8 studies Reviewed papers
6 acupoints Major acupoints used
73% Mean symptom improvement rate

Summary

A comprehensive review of treatment mechanisms and clinical evidence of acupuncture for nasal obstruction symptoms due to deviated nasal septum. Mechanisms of nasal mucosal blood flow modulation at acupoints such as LI20, LI4, and GV23, and nasal airway patency improvement effects were analyzed, with potential as conservative treatment before and after surgery discussed.

Key Conclusion

Acupuncture can be utilized as a conservative treatment for nasal obstruction symptoms in patients with deviated nasal septum, and well-designed clinical trials are needed in the future.

Case Study ENT Disorders

Effects of Nasal Irrigation and Herbal Medicine Combined Treatment for Chronic Rhinitis: A Case Report of 7 Cases

오승현, 김진아, 박동우, et al.

한방안이비인후피부과학회지 (2024)

61% TNSS reduction rate
7 patients Number of cases
8 weeks Treatment duration

Combined nasal irrigation and herbal medicine treatment shows synergistic effects in symptom relief of chronic rhinitis patients, and large-scale studies are warranted.

Case Study ENT Disorders

Effects of Nasal Irrigation and Herbal Medicine Combined Treatment for Chronic Rhinitis: A Case Report of 7 Cases

오승현, 김진아, 박동우, et al. 한방안이비인후피부과학회지 (2024)
61% TNSS reduction rate
7 patients Number of cases
8 weeks Treatment duration

Summary

A case report on 7 patients with chronic rhinitis of 6 months or more duration who received combined saline nasal irrigation and modified Changi-san for 8 weeks. All patients showed average 61% reduction in Total Nasal Symptom Score (TNSS), with particularly notable improvements in nasal obstruction and postnasal drip symptoms.

Key Conclusion

Combined nasal irrigation and herbal medicine treatment shows synergistic effects in symptom relief of chronic rhinitis patients, and large-scale studies are warranted.