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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Total 93 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Meta-Analysis ENT Disorders

Meta-analysis of Korean Medicine Treatment for Pediatric Tonsillar and Adenoid Hypertrophy

Won JY, Choi SM, Lee MS, et al.

Pediatric Allergy and Immunology (2023)

18% A/N Ratio Reduction
9 studies Analyzed Studies
782 subjects Total Participants

Korean medicine treatment is an effective alternative for non-surgical management of pediatric tonsillar and adenoid hypertrophy.

View Source 2023
Meta-Analysis ENT Disorders

Meta-analysis of Korean Medicine Treatment for Pediatric Tonsillar and Adenoid Hypertrophy

Won JY, Choi SM, Lee MS, et al. Pediatric Allergy and Immunology (2023)
18% A/N Ratio Reduction
9 studies Analyzed Studies
782 subjects Total Participants

Summary

Nine RCTs (782 subjects total) on Korean medicine treatment for pediatric tonsillar and adenoid hypertrophy were meta-analyzed. The herbal medicine (Hyungaeyongyo-tang, Bojungikgi-tang, etc.) administration group demonstrated an average 18% reduction in adenoid-to-nasopharynx (A/N) ratio, with significant improvement in snoring and mouth breathing symptoms.

Key Conclusion

Korean medicine treatment is an effective alternative for non-surgical management of pediatric tonsillar and adenoid hypertrophy.

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Narrative Review ENT Disorders

Recent Trends in Korean Medicine Treatment for Postnasal Drip Syndrome: A Narrative Review

이다현, 김상우, 박혜린, et al.

대한한의학회지 (2024)

18 studies Reviewed papers
8 prescriptions Major herbal prescriptions
5 years Review period

Korean medicine treatment for postnasal drip syndrome focuses on nasal secretion regulation and mucosal function recovery, with effective integrative approach.

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Narrative Review ENT Disorders

Recent Trends in Korean Medicine Treatment for Postnasal Drip Syndrome: A Narrative Review

이다현, 김상우, 박혜린, et al. 대한한의학회지 (2024)
18 studies Reviewed papers
8 prescriptions Major herbal prescriptions
5 years Review period

Summary

A narrative review comprehensively analyzing Korean medicine pathophysiological interpretation and treatment of postnasal drip syndrome. Clinical evidence for nasal prescriptions including Magnoliae flos and Xanthii fructus was analyzed, along with adjunctive effects of nasal irrigation and fumigation. A total of 18 related studies were reviewed.

Key Conclusion

Korean medicine treatment for postnasal drip syndrome focuses on nasal secretion regulation and mucosal function recovery, with effective integrative approach.

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Case Study ENT Disorders

Recurrence Prevention Effect of Korean Medicine Combination Treatment for Recurrent Tonsillitis: A Case Report

한서윤, 정우진, 김태리, et al.

한방안이비인후피부과학회지 (2023)

73% Recurrence reduction rate
9 patients Number of cases
6 months Treatment duration

Korean medicine combination treatment markedly reduces recurrence rate in recurrent tonsillitis patients and may serve as an alternative to surgical treatment.

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Case Study ENT Disorders

Recurrence Prevention Effect of Korean Medicine Combination Treatment for Recurrent Tonsillitis: A Case Report

한서윤, 정우진, 김태리, et al. 한방안이비인후피부과학회지 (2023)
73% Recurrence reduction rate
9 patients Number of cases
6 months Treatment duration

Summary

A case report performing herbal medicine (modified Bangpungtongseong-san), acupuncture, and pharmacopuncture for 6 months in 9 patients with recurrent tonsillitis (4 or more times annually). Tonsillitis recurrence decreased by an average of 73% during treatment period, with improvements in tonsillar hypertrophy grade.

Key Conclusion

Korean medicine combination treatment markedly reduces recurrence rate in recurrent tonsillitis patients and may serve as an alternative to surgical treatment.

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Cross-Sectional ENT Disorders

Anti-inflammatory Effect of Modified Eungyo-san for Acute Laryngitis: A Cross-Sectional Study

Lim SH, Kang BK, You SS, et al.

동의생리병리학회지 (2023)

67% Pharyngeal Pain Reduction
79% Laryngeal Finding Improvement
82 subjects Participants

Modified Eungyo-san is effective for rapid symptom relief and laryngeal inflammatory finding improvement in acute laryngitis.

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Cross-Sectional ENT Disorders

Anti-inflammatory Effect of Modified Eungyo-san for Acute Laryngitis: A Cross-Sectional Study

Lim SH, Kang BK, You SS, et al. 동의생리병리학회지 (2023)
67% Pharyngeal Pain Reduction
79% Laryngeal Finding Improvement
82 subjects Participants

Summary

Eighty-two patients with acute laryngitis were compared for pharyngeal pain VAS, laryngoscopic findings, and serum inflammatory markers before and after modified Eungyo-san administration. After 5 days of treatment, pharyngeal pain decreased by an average of 67%, with marked improvement in laryngeal erythema and edema findings in 79%.

Key Conclusion

Modified Eungyo-san is effective for rapid symptom relief and laryngeal inflammatory finding improvement in acute laryngitis.

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Narrative Review ENT Disorders

Narrative Review of Korean Medicine Treatment for Functional Voice Disorders

Park DI, Kim AR, Leem JT, et al.

Integrative Medicine Research (2024)

19 papers Reviewed Papers
85% Average Efficacy Rate
3.2 sec Average MPT Improvement

Korean medicine treatment has potential for improving various voice parameters in functional voice disorders, with standardized clinical trials required.

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Narrative Review ENT Disorders

Narrative Review of Korean Medicine Treatment for Functional Voice Disorders

Park DI, Kim AR, Leem JT, et al. Integrative Medicine Research (2024)
19 papers Reviewed Papers
85% Average Efficacy Rate
3.2 sec Average MPT Improvement

Summary

Nineteen articles on Korean medicine treatment for functional voice disorders were reviewed, with acupuncture (Renying, Tiantu, Hegu) and herbal medicines such as Hyangsayangwi-tang predominantly utilized. In multiple studies, maximum phonation time (MPT) and fundamental frequency stability improved, with significant reduction in vocal fatigue.

Key Conclusion

Korean medicine treatment has potential for improving various voice parameters in functional voice disorders, with standardized clinical trials required.

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RCT ENT Disorders

Effect of Combined Acupuncture and Voice Therapy for Vocal Cord Nodules: A Randomized Controlled Trial

Song MY, Choi TY, Shin BC, et al.

Journal of Voice (2023)

47% VHI Reduction Rate
74 subjects Participants
8 weeks Treatment Period

Adjunctive acupuncture promotes voice function recovery and nodule size reduction in vocal cord nodules.

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RCT ENT Disorders

Effect of Combined Acupuncture and Voice Therapy for Vocal Cord Nodules: A Randomized Controlled Trial

Song MY, Choi TY, Shin BC, et al. Journal of Voice (2023)
47% VHI Reduction Rate
74 subjects Participants
8 weeks Treatment Period

Summary

Seventy-four patients with vocal cord nodules were assigned to voice therapy monotherapy or voice therapy plus acupuncture combination groups for 8 weeks of treatment. The combination group demonstrated a 47% reduction in VHI (Voice Handicap Index), significantly superior to monotherapy (31%), with greater nodule size reduction also observed on laryngeal stroboscopy.

Key Conclusion

Adjunctive acupuncture promotes voice function recovery and nodule size reduction in vocal cord nodules.

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Case Study ENT Disorders

Effect of Bee Venom Pharmacopuncture for Chronic Pharyngeal Pain: A Case Series of 15

Ahn YC, Son CG, Lee HJ, et al.

Journal of Pharmacopuncture (2024)

61% Pain Reduction Rate
73% Globus Sensation Improvement
15 cases Case Number

Bee venom pharmacopuncture is effective for pain and globus sensation relief in chronic pharyngeal pain, with favorable safety.

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Case Study ENT Disorders

Effect of Bee Venom Pharmacopuncture for Chronic Pharyngeal Pain: A Case Series of 15

Ahn YC, Son CG, Lee HJ, et al. Journal of Pharmacopuncture (2024)
61% Pain Reduction Rate
73% Globus Sensation Improvement
15 cases Case Number

Summary

Fifteen patients with chronic pharyngeal pain persisting more than 3 months received bee venom pharmacopuncture at Tiantu (CV22) and Lianquan (CV23) twice weekly for 6 weeks. VAS pain scores decreased by an average of 61%, and pharyngeal globus sensation (GIS) improved by 73%. Adverse effects were limited to 2 cases of mild local erythema.

Key Conclusion

Bee venom pharmacopuncture is effective for pain and globus sensation relief in chronic pharyngeal pain, with favorable safety.

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Systematic Review ENT Disorders

Therapeutic Effect of Banhasasim-tang for Laryngopharyngeal Reflux Disease: A Systematic Review

Kwon CY, Lee BH, Kim JH, et al.

Journal of Gastroenterology and Hepatology (2023)

11 studies Reviewed Studies
82% Average RSI Improvement
4 weeks Average Onset of Effect

Banhasasim-tang is effective for symptom and laryngeal finding improvement in laryngopharyngeal reflux disease, and combination with PPI is recommended.

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Systematic Review ENT Disorders

Therapeutic Effect of Banhasasim-tang for Laryngopharyngeal Reflux Disease: A Systematic Review

Kwon CY, Lee BH, Kim JH, et al. Journal of Gastroenterology and Hepatology (2023)
11 studies Reviewed Studies
82% Average RSI Improvement
4 weeks Average Onset of Effect

Summary

Eleven clinical studies evaluating the effects of Banhasasim-tang and modified prescriptions for laryngopharyngeal reflux disease (LPR) were systematically reviewed. In most studies, RSI (Reflux Symptom Index) and RFS (Reflux Finding Score) significantly improved, with faster symptom alleviation when combined with PPI compared to PPI monotherapy.

Key Conclusion

Banhasasim-tang is effective for symptom and laryngeal finding improvement in laryngopharyngeal reflux disease, and combination with PPI is recommended.

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RCT ENT Disorders

Effect of Combined Acupuncture and Nasal Irrigation for Chronic Sinusitis: A Randomized Controlled Trial

Jeon YJ, Kim SW, Park YJ, et al.

American Journal of Rhinology & Allergy (2024)

52% SNOT-22 Reduction
98 subjects Participants
10 weeks Treatment Period

Adjunctive acupuncture enhances treatment efficacy in both subjective symptoms and objective findings of chronic sinusitis.

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RCT ENT Disorders

Effect of Combined Acupuncture and Nasal Irrigation for Chronic Sinusitis: A Randomized Controlled Trial

Jeon YJ, Kim SW, Park YJ, et al. American Journal of Rhinology & Allergy (2024)
52% SNOT-22 Reduction
98 subjects Participants
10 weeks Treatment Period

Summary

Ninety-eight patients with chronic sinusitis were assigned to nasal irrigation monotherapy or nasal irrigation plus acupuncture combination groups for 10 weeks of treatment. The combination group demonstrated a 52% reduction in SNOT-22 scores, significantly superior to monotherapy (34%), with higher endoscopic improvement rates also observed in the combination group.

Key Conclusion

Adjunctive acupuncture enhances treatment efficacy in both subjective symptoms and objective findings of chronic sinusitis.

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Before-After ENT Disorders

Anti-inflammatory Effect of Hyungaeyongyo-tang for Acute Sinusitis: A Pre-Post Comparison Study

Cho SI, Lim JH, Kang WC, et al.

대한한방이비인후피부과학회지 (2023)

45% CT Score Reduction
81% CRP Normalization Rate
63 subjects Participants

Hyungaeyongyo-tang is an effective herbal prescription for inflammatory marker improvement and radiological resolution in acute sinusitis.

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Before-After ENT Disorders

Anti-inflammatory Effect of Hyungaeyongyo-tang for Acute Sinusitis: A Pre-Post Comparison Study

Cho SI, Lim JH, Kang WC, et al. 대한한방이비인후피부과학회지 (2023)
45% CT Score Reduction
81% CRP Normalization Rate
63 subjects Participants

Summary

Sixty-three patients with acute sinusitis received Hyungaeyongyo-tang for 2 weeks, with pre- and post-treatment CT findings, CRP, and nasal symptom scores compared. Lund-Mackay CT scores decreased by an average of 45%, and the rate of CRP recovery to normal range reached 81%.

Key Conclusion

Hyungaeyongyo-tang is an effective herbal prescription for inflammatory marker improvement and radiological resolution in acute sinusitis.

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Meta-Analysis ENT Disorders

Systematic Review and Meta-analysis of Korean Medicine Treatment for Nasal Polyps

Moon SK, Jang JY, Woo CH, et al.

Rhinology (2024)

32% Polyp Size Reduction
11% Recurrence Rate (Treatment)
16 studies Analyzed Studies

Korean medicine treatment is an effective complementary strategy for nasal polyp size reduction and postoperative recurrence prevention.

View Source 2024
Meta-Analysis ENT Disorders

Systematic Review and Meta-analysis of Korean Medicine Treatment for Nasal Polyps

Moon SK, Jang JY, Woo CH, et al. Rhinology (2024)
32% Polyp Size Reduction
11% Recurrence Rate (Treatment)
16 studies Analyzed Studies

Summary

Sixteen clinical studies (1,234 subjects total) evaluating Korean medicine treatment (herbal medicine, acupuncture, pharmacopuncture) for nasal polyps were meta-analyzed. The Korean medicine group demonstrated an average 32% reduction in polyp size, with herbal medicine administration for postoperative recurrence prevention showing significantly lower recurrence rates (11%) compared with controls (28%).

Key Conclusion

Korean medicine treatment is an effective complementary strategy for nasal polyp size reduction and postoperative recurrence prevention.

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Cohort Study ENT Disorders

Symptom Alleviation Effect of Acupuncture for Nasal Obstruction Accompanying Septal Deviation: A Cohort Study

Yoo DG, Shin SH, Lee JY, et al.

Clinical Otolaryngology (2023)

38% NOSE Score Improvement
22% Nasal Cross-Section Increase
92 subjects Participants

Acupuncture significantly alleviates nasal obstruction symptoms as a conservative pre-surgical treatment for septal deviation.

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Cohort Study ENT Disorders

Symptom Alleviation Effect of Acupuncture for Nasal Obstruction Accompanying Septal Deviation: A Cohort Study

Yoo DG, Shin SH, Lee JY, et al. Clinical Otolaryngology (2023)
38% NOSE Score Improvement
22% Nasal Cross-Section Increase
92 subjects Participants

Summary

Ninety-two patients with septal deviation complaining of nasal obstruction received acupuncture at Yingxiang (LI20), Bitong (EX-HN8), and Yintang (EX-HN3) for 6 weeks. NOSE questionnaire scores improved by an average of 38%, and minimum cross-sectional area on acoustic rhinometry (AR) increased by 22%.

Key Conclusion

Acupuncture significantly alleviates nasal obstruction symptoms as a conservative pre-surgical treatment for septal deviation.

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